CRISPR-CAS9 D10A nickase target-specific fluorescent labeling of double strand DNA for whole genome mapping and structural variation analysis

Nucleic Acids Research

Volumn 44, Issue 2, 2016, Pages e11-

  McCaffrey, Jennifer ^a   Sibert, Justin ^a   Zhang, Bin ^a   Zhang, Yonggang ^b   Hu, Wenhui ^b   Riethman, Harold ^c   Xiao, Ming ^a  

^a DREXEL UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Wistar Institution   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9 D10A NICKASE; DNA POLYMERASE; DOUBLE STRANDED DNA; NANOCHANNEL; NUCLEOTIDE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; DEOXYRIBONUCLEASE I; DNA; ENDONUCLEASE; FLUORESCENT DYE; GUIDE RNA;

ANALYSIS; ARTICLE; CHEMICAL LABELING; DNA BASE COMPOSITION; DNA STRUCTURE; DUF DOMAIN; GENE MAPPING; HIGH THROUGHPUT SEQUENCING; HUMAN; IN VITRO STUDY; NICK LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; RNA SEQUENCE; SEQUENCE MOTIF LABELING; STRUCTURAL VARIATION ANALYSIS; TELOMERE; AMINO ACID SUBSTITUTION; BACTERIAL ARTIFICIAL CHROMOSOME; CHEMISTRY; CHROMOSOMAL MAPPING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; GENETICS; HUMAN GENOME; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MUTATION; PLASMID; PROCEDURES; PROTEIN TERTIARY STRUCTURE; TUNEL ASSAY;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; DEOXYRIBONUCLEASE I; DNA; ENDONUCLEASES; FLUORESCENT DYES; GENOME, HUMAN; HIV-1; HUMANS; IN SITU NICK-END LABELING; MUTATION; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; RNA, GUIDE;

EID: 84966393368     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv878     Document Type: Article

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