-
1
-
-
44449131447
-
Huntington's disease: from pathology and genetics to potential therapies
-
Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, et al. (2008) Huntington's disease: from pathology and genetics to potential therapies. Biochem J 412: 191-209.
-
(2008)
Biochem J
, vol.412
, pp. 191-209
-
-
Imarisio, S.1
Carmichael, J.2
Korolchuk, V.3
Chen, C.W.4
Saiki, S.5
-
2
-
-
35348877164
-
Transcriptional signatures in Huntington's disease
-
Cha JH, (2007) Transcriptional signatures in Huntington's disease. Prog Neurobiol 83: 228-48.
-
(2007)
Prog Neurobiol
, vol.83
, pp. 228-248
-
-
Cha, J.H.1
-
3
-
-
0037408279
-
Transcriptional abnormalities in Huntington disease
-
Sugars KL, Rubinsztein DC, (2003) Transcriptional abnormalities in Huntington disease. Trends Genet 19: 233-238.
-
(2003)
Trends Genet
, vol.19
, pp. 233-238
-
-
Sugars, K.L.1
Rubinsztein, D.C.2
-
4
-
-
21544450545
-
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease
-
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, et al. (2005) p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron 47: 29-41.
-
(2005)
Neuron
, vol.47
, pp. 29-41
-
-
Bae, B.I.1
Xu, H.2
Igarashi, S.3
Fujimuro, M.4
Agrawal, N.5
-
5
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, et al. (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 296: 2238-2243.
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
-
6
-
-
0141742228
-
The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor
-
Takano H, Gusella JF, (2002) The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor. BMC Neuroscience 14: 3-15.
-
(2002)
BMC Neuroscience
, vol.14
, pp. 3-15
-
-
Takano, H.1
Gusella, J.F.2
-
7
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora FC Jr, Sasaki M, Peters MF, Huang H, Cooper JK, et al. (2001) Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 291: 2423-2428.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
-
8
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, et al. (2000) The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc Natl Acad Sci 97: 6763-6768.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
-
9
-
-
0032450856
-
Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins
-
Huang CC, Faber PW, Persichetti F, Mittal V, Vonsattel JP, et al. (1998) Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins. Somat Cell Mol Genet 24: 217-233.
-
(1998)
Somat Cell Mol Genet
, vol.24
, pp. 217-233
-
-
Huang, C.C.1
Faber, P.W.2
Persichetti, F.3
Mittal, V.4
Vonsattel, J.P.5
-
10
-
-
30044438329
-
p53 tumor suppressor protein regulates the levels of huntingtin gene expression
-
Feng Z, Jin S, Zupnick A, Hoh J, de Stanchina E, et al. (2006) p53 tumor suppressor protein regulates the levels of huntingtin gene expression. Oncogene 25: 1-7.
-
(2006)
Oncogene
, vol.25
, pp. 1-7
-
-
Feng, Z.1
Jin, S.2
Zupnick, A.3
Hoh, J.4
de Stanchina, E.5
-
11
-
-
33749988461
-
Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis
-
Ryan AB, Zeitlin SO, Scrable H, (2006) Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis. Neurobiol Dis 24: 419-427.
-
(2006)
Neurobiol Dis
, vol.24
, pp. 419-427
-
-
Ryan, A.B.1
Zeitlin, S.O.2
Scrable, H.3
-
12
-
-
4644307407
-
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity
-
Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH, et al. (2004) Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. J Neurosci 24: 7999-8008.
-
(2004)
J Neurosci
, vol.24
, pp. 7999-8008
-
-
Khoshnan, A.1
Ko, J.2
Watkin, E.E.3
Paige, L.A.4
Reinhart, P.H.5
-
13
-
-
32644481227
-
Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction
-
Goswami A, Dikshit P, Mishra A, Mulherkar S, Nukina N, et al. (2006) Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction. Biochem Biophys Res Commun 342: 184-190.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 184-190
-
-
Goswami, A.1
Dikshit, P.2
Mishra, A.3
Mulherkar, S.4
Nukina, N.5
-
14
-
-
58149328522
-
Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction
-
Godavarthi SK, Narender D, Mishra A, Goswami A, Rao SN, et al. (2009) Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction. J Neurochem 108: 787-795.
-
(2009)
J Neurochem
, vol.108
, pp. 787-795
-
-
Godavarthi, S.K.1
Narender, D.2
Mishra, A.3
Goswami, A.4
Rao, S.N.5
-
15
-
-
41549110185
-
Control of protein synthesis and mRNA degradation by microRNAs
-
Liu J, (2008) Control of protein synthesis and mRNA degradation by microRNAs. Curr Opin Cell Biol 20: 214-221.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 214-221
-
-
Liu, J.1
-
16
-
-
43449090367
-
MicroRNA-10a binds the 5′ UTR of ribosomal protein mRNAs and enhances their translation
-
Ørom UA, Nielsen FC, Lund AH, (2008) MicroRNA-10a binds the 5′ UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 30: 460-471.
-
(2008)
Mol Cell
, vol.30
, pp. 460-471
-
-
Ørom, U.A.1
Nielsen, F.C.2
Lund, A.H.3
-
17
-
-
40349094597
-
MicroRNA-373 induces expression of genes with complementary promoter sequences
-
Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R, (2008) MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci 105: 1608-1613.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 1608-1613
-
-
Place, R.F.1
Li, L.C.2
Pookot, D.3
Noonan, E.J.4
Dahiya, R.5
-
18
-
-
54549108798
-
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
-
Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I, (2008) MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455: 1124-1128.
-
(2008)
Nature
, vol.455
, pp. 1124-1128
-
-
Tay, Y.1
Zhang, J.2
Thomson, A.M.3
Lim, B.4
Rigoutsos, I.5
-
19
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
20
-
-
33748587841
-
A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
-
Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, et al. (2006) A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 126: 1203-1217.
-
(2006)
Cell
, vol.126
, pp. 1203-1217
-
-
Miranda, K.C.1
Huynh, T.2
Tay, Y.3
Ang, Y.S.4
Tam, W.L.5
-
21
-
-
28044439909
-
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis
-
Vo N, Klein ME, Varlamova O, Keller DM, Yamamoto T, et al. (2005) A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci 102: 16426-16431.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 16426-16431
-
-
Vo, N.1
Klein, M.E.2
Varlamova, O.3
Keller, D.M.4
Yamamoto, T.5
-
22
-
-
35748961986
-
p53 enters the microRNA world
-
Hermeking H, (2007) p53 enters the microRNA world. Cancer Cell 12: 414-418.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
-
23
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
-
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, et al. (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 26: 745-752.
-
(2007)
Mol Cell
, vol.26
, pp. 745-752
-
-
Chang, T.C.1
Wentzel, E.A.2
Kent, O.A.3
Ramachandran, K.4
Mullendore, M.5
-
24
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, et al. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447: 1130-1134.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
de Stanchina, E.4
Xuan, Z.5
-
25
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, et al. (2009) Modulation of microRNA processing by p53. Nature 460: 529-533.
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
Yamagata, K.2
Sugimoto, K.3
Iwamoto, T.4
Kato, S.5
-
26
-
-
34250868124
-
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
-
Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, et al. (2007) Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6: 1586-1593.
-
(2007)
Cell Cycle
, vol.6
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
Lodygin, D.4
Epanchintsev, A.5
-
27
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, et al. (2007) Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 26: 731-743.
-
(2007)
Mol Cell
, vol.26
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
Spector, Y.4
Rosenfeld, N.5
-
28
-
-
64349101658
-
MicroRNA-125b is a novel negative regulator of p53
-
Le MTN, The C, Shyh-Chang N, Xie H, Zhou B, et al. (2009) MicroRNA-125b is a novel negative regulator of p53. Genes Dev 23: 862-876.
-
(2009)
Genes Dev
, vol.23
, pp. 862-876
-
-
Le, M.T.N.1
The, C.2
Shyh-Chang, N.3
Xie, H.4
Zhou, B.5
-
29
-
-
33747608638
-
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov KD, Boldin MP, Chang KJ, Baltimore D, (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci 103: 12481-12486.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
30
-
-
39649092720
-
A microRNA-based gene dysregulation pathway in Huntington's disease
-
Johnson R, Zuccato C, Belyaev ND, Guest DJ, Cattaneo E, et al. (2008) A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol Dis 29: 438-445.
-
(2008)
Neurobiol Dis
, vol.29
, pp. 438-445
-
-
Johnson, R.1
Zuccato, C.2
Belyaev, N.D.3
Guest, D.J.4
Cattaneo, E.5
-
31
-
-
58149375393
-
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
-
Packer AN, Xing Y, Harper SQ, Jones L, Davidson BL, (2008) The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci 28: 14341-14346.
-
(2008)
J Neurosci
, vol.28
, pp. 14341-14346
-
-
Packer, A.N.1
Xing, Y.2
Harper, S.Q.3
Jones, L.4
Davidson, B.L.5
-
32
-
-
0034703869
-
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
-
Trettel F, Rigamonti D, Hilditch-Maguire P, Wheeler VC, Sharp AH, et al. (2000) Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum Mol Genet 9: 2799-2809.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2799-2809
-
-
Trettel, F.1
Rigamonti, D.2
Hilditch-Maguire, P.3
Wheeler, V.C.4
Sharp, A.H.5
-
33
-
-
77953025795
-
Altered microRNAs in STHdh(Q111)/Hdh(Q111) cells: miR-146a targets TBP
-
Sinha M, Ghose J, Das E, Bhattarcharyya NP, (2010) Altered microRNAs in STHdh(Q111)/Hdh(Q111) cells: miR-146a targets TBP. Biochem Biophys Res Commun 396: 742-747.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 742-747
-
-
Sinha, M.1
Ghose, J.2
Das, E.3
Bhattarcharyya, N.P.4
-
34
-
-
63049086873
-
IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin
-
Chakravorty M, Datta De D, Choudhury A, Roychoudhury S, (2009) IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. Int J Biochem Cell Biol 41: 1502-1510.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1502-1510
-
-
Chakravorty, M.1
de Datta, D.2
Choudhury, A.3
Roychoudhury, S.4
-
35
-
-
0028167846
-
Inhibition of NF-kappa B by sodium salicylate and aspirin
-
Kopp E, Ghosh S, (1994) Inhibition of NF-kappa B by sodium salicylate and aspirin. Science 265: 956-959.
-
(1994)
Science
, vol.265
, pp. 956-959
-
-
Kopp, E.1
Ghosh, S.2
-
36
-
-
0347755643
-
The MicroRNA Registry
-
Griffiths-Jones S, (2004) The MicroRNA Registry. Nucl Acids Res 32 (Database Issue): D109-D11155.
-
(2004)
Nucl Acids Res
, vol.32
, Issue.Database Issue
, pp. 109-11155
-
-
Griffiths-Jones, S.1
-
37
-
-
44649108882
-
Activated p53 induces NFkappaB DNA binding but suppresses its transcriptional activation
-
Kawauchi K, Araki K, Tobiume K, Tanaka N, (2008) Activated p53 induces NFkappaB DNA binding but suppresses its transcriptional activation. Biochem Biophys Res Commun 372: 137-141.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 137-141
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
38
-
-
0033593217
-
CREB-binding protein is a nuclear integrator of nuclear factor-κB and p53 signaling
-
Wadgaonkar R, Phelps KM, Haque Z, Williams AJ, Silverman ES, et al. (1999) CREB-binding protein is a nuclear integrator of nuclear factor-κB and p53 signaling. J Biol Chem 274: 1879-1882.
-
(1999)
J Biol Chem
, vol.274
, pp. 1879-1882
-
-
Wadgaonkar, R.1
Phelps, K.M.2
Haque, Z.3
Williams, A.J.4
Silverman, E.S.5
-
39
-
-
0032954928
-
Transcriptional cross talk between NF-kB and p53
-
Webster GA, Perkins ND, (1999) Transcriptional cross talk between NF-kB and p53. Mol Cell Biol 19: 3485-3495.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
40
-
-
34047248402
-
Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB
-
Huang WC, Ju TK, Hung MC, Chen CC, (2007) Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. Mol Cell 26: 75-87.
-
(2007)
Mol Cell
, vol.26
, pp. 75-87
-
-
Huang, W.C.1
Ju, T.K.2
Hung, M.C.3
Chen, C.C.4
-
41
-
-
2942716907
-
p53 induces NF- kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
-
Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC, (2004) p53 induces NF- kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem 279: 26115-26125.
-
(2004)
J Biol Chem
, vol.279
, pp. 26115-26125
-
-
Bohuslav, J.1
Chen, L.F.2
Kwon, H.3
Mu, Y.4
Greene, W.C.5
-
42
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan KM, Ernst MK, Rice NR, Vousden KH, (2000) Role of NF-kappaB in p53-mediated programmed cell death. Nature 404: 892-897.
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
43
-
-
34247204753
-
5-Fluorouracil Activation of p53 Involves an MDM2-Ribosomal Protein Interaction
-
Xiao-Xin S, Mu-Shui D, Hua L, (2007) 5-Fluorouracil Activation of p53 Involves an MDM2-Ribosomal Protein Interaction. J Biol Chem 282: 8052-8059.
-
(2007)
J Biol Chem
, vol.282
, pp. 8052-8059
-
-
Xiao-Xin, S.1
Mu-Shui, D.2
Hua, L.3
-
44
-
-
38649110478
-
Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range
-
Majumder P, Raychaudhuri S, Chattopadhyay B, Bhattacharyya NP, (2007) Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range. Cell Mol Neurobiol 27: 1127-1145.
-
(2007)
Cell Mol Neurobiol
, vol.27
, pp. 1127-1145
-
-
Majumder, P.1
Raychaudhuri, S.2
Chattopadhyay, B.3
Bhattacharyya, N.P.4
-
45
-
-
37849012236
-
HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity
-
Raychaudhuri S, Sinha M, Mukhopadhyay D, Bhattacharyya NP, (2008) HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity. Hum Mol Genet 17: 240-255.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 240-255
-
-
Raychaudhuri, S.1
Sinha, M.2
Mukhopadhyay, D.3
Bhattacharyya, N.P.4
-
46
-
-
80052062718
-
Protective Effect of Hsp70 Molecular Chaperone in Polyglutamine Diseases Is Realized by Sequestering of GAPDH
-
Kaznacheeva AV, Guzhova IV, Margulis BA, (2009) Protective Effect of Hsp70 Molecular Chaperone in Polyglutamine Diseases Is Realized by Sequestering of GAPDH. Biologicheskie Membrany 26: 314.
-
(2009)
Biologicheskie Membrany
, vol.26
, pp. 314
-
-
Kaznacheeva, A.V.1
Guzhova, I.V.2
Margulis, B.A.3
-
47
-
-
16044373842
-
Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice
-
Mangarini L, Sathasivam K, Seller M, Cozens B, Harper A, et al. (1996) Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice. Cell 87: 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
-
48
-
-
78650954319
-
Altered microRNA regulation in Huntington's disease models
-
Lee ST, Chu K, Im WS, Yoon HJ, Im JY, et al. (2010) Altered microRNA regulation in Huntington's disease models. Exp Neurol 227 (1): 172-179.
-
(2010)
Exp Neurol
, vol.227
, Issue.1
, pp. 172-179
-
-
Lee, S.T.1
Chu, K.2
Im, W.S.3
Yoon, H.J.4
Im, J.Y.5
-
49
-
-
57649119790
-
An NF-kB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer's Disease and in Stressed Human Brain Cells
-
Lukiw WJ, Zhao Y, Cui JG, (2008) An NF-kB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer's Disease and in Stressed Human Brain Cells. J of Biol Chem 283: 31315-31322.
-
(2008)
J of Biol Chem
, vol.283
, pp. 31315-31322
-
-
Lukiw, W.J.1
Zhao, Y.2
Cui, J.G.3
-
50
-
-
74049090905
-
HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory Signalling
-
Hill JM, Zhao Y, Clement C, Neumann DM, Lukiw WJ, (2009) HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory Signalling. Neuroreport 20 (16): 1500-1505.
-
(2009)
Neuroreport
, vol.20
, Issue.16
, pp. 1500-1505
-
-
Hill, J.M.1
Zhao, Y.2
Clement, C.3
Neumann, D.M.4
Lukiw, W.J.5
-
51
-
-
77949549835
-
Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy
-
Aronica E, Fluiter K, Iyer A, Zurolo E, Vreijiling J, et al. (2010) Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy. Eur J Neurosci 31 (6): 1100-7.
-
(2010)
Eur J Neurosci
, vol.31
, Issue.6
, pp. 1100-1107
-
-
Aronica, E.1
Fluiter, K.2
Iyer, A.3
Zurolo, E.4
Vreijiling, J.5
-
52
-
-
56649112767
-
A miRNA signature of prion induced neurodegeneration
-
Saba R, Goodman CD, Huzarewich LCH, Robertson C, Booth SA, (2008) A miRNA signature of prion induced neurodegeneration. PLoS One 3 (11): e3652.
-
(2008)
PLoS One
, vol.3
, Issue.11
-
-
Saba, R.1
Goodman, C.D.2
Huzarewich, L.C.H.3
Robertson, C.4
Booth, S.A.5
-
53
-
-
4644237189
-
Fast and effective prediction of microRNA/target duplexes
-
Rehmsmeier M, Steffen P, Höchsmann M, Giegerich R, (2004) Fast and effective prediction of microRNA/target duplexes. RNA 10: 1507-1517.
-
(2004)
RNA
, vol.10
, pp. 1507-1517
-
-
Rehmsmeier, M.1
Steffen, P.2
Höchsmann, M.3
Giegerich, R.4
-
54
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA, Baltimore D, (1996) An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274: 782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
55
-
-
0032579555
-
A role for nuclear factor kappaB in the antiapoptotic function of insulin
-
Bertrand F, Atfi A, Cadoret A, L'Allemain G, Robin H, et al. (1998) A role for nuclear factor kappaB in the antiapoptotic function of insulin. J Biol Chem 273: 2931-2938.
-
(1998)
J Biol Chem
, vol.273
, pp. 2931-2938
-
-
Bertrand, F.1
Atfi, A.2
Cadoret, A.3
L'Allemain, G.4
Robin, H.5
-
56
-
-
0031838786
-
Response of tumour cells to hypoxia: role of p53 and NFkB
-
Royds JA, Dower SK, Qwarnstrom EE, Lewis CE, (1998) Response of tumour cells to hypoxia: role of p53 and NFkB. Mol Pathol 51: 55-61.
-
(1998)
Mol Pathol
, vol.51
, pp. 55-61
-
-
Royds, J.A.1
Dower, S.K.2
Qwarnstrom, E.E.3
Lewis, C.E.4
-
57
-
-
0346749473
-
Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells
-
Gines S, Ivanova E, Seong IS, Saura CA, MacDonald ME, (2003) Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells. J Biol Chem 278: 50514-50522.
-
(2003)
J Biol Chem
, vol.278
, pp. 50514-50522
-
-
Gines, S.1
Ivanova, E.2
Seong, I.S.3
Saura, C.A.4
MacDonald, M.E.5
-
58
-
-
0037335074
-
Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice
-
Gines S, Seong IS, Fossale E, Ivanova E, Trettel F, et al. (2003) Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice. Hum Mol Genet 12: 497-508.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 497-508
-
-
Gines, S.1
Seong, I.S.2
Fossale, E.3
Ivanova, E.4
Trettel, F.5
-
59
-
-
34548399406
-
Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism
-
Lee JM, Ivanova EV, Seong IS, Cashorali T, Kohane I, et al. (2007) Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. PLoS Genet 3 (8): e135.
-
(2007)
PLoS Genet
, vol.3
, Issue.8
-
-
Lee, J.M.1
Ivanova, E.V.2
Seong, I.S.3
Cashorali, T.4
Kohane, I.5
-
60
-
-
54849422301
-
Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner
-
Benn CL, SunT, Sadri-Vakili G, McFarland KN, DiRocco DP, et al. (2008) Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. J Neurosci 28: 10720-10733.
-
(2008)
J Neurosci
, vol.28
, pp. 10720-10733
-
-
Benn, C.L.1
Sun, T.2
Sadri-Vakili, G.3
McFarland, K.N.4
DiRocco, D.P.5
-
61
-
-
54449092109
-
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease
-
Quintanilla RA, Jin YN, Fuenzalida K, Bronfman M, Johnson G, (2008) Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease. J Biol Chem 283: 25628-25637.
-
(2008)
J Biol Chem
, vol.283
, pp. 25628-25637
-
-
Quintanilla, R.A.1
Jin, Y.N.2
Fuenzalida, K.3
Bronfman, M.4
Johnson, G.5
-
62
-
-
43549092044
-
Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells
-
Xifró X, García-Martínez JM, Del Toro D, Alberch J, Pérez-Navarro E, (2008) Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells. J Neurochem 105: 596-612.
-
(2008)
J Neurochem
, vol.105
, pp. 596-612
-
-
Xifró, X.1
García-Martínez, J.M.2
Del Toro, D.3
Alberch, J.4
Pérez-Navarro, E.5
-
63
-
-
60849125108
-
Increased expression of Bim contributes to the potentiation of serum deprivation-induced apoptotic cell death in Huntington's disease knock-in striatal cell line
-
Kong PJ, Kil MO, Lee H, Kim SS, Johnson GV, et al. (2009) Increased expression of Bim contributes to the potentiation of serum deprivation-induced apoptotic cell death in Huntington's disease knock-in striatal cell line. Neurol Res 31: 77-83.
-
(2009)
Neurol Res
, vol.31
, pp. 77-83
-
-
Kong, P.J.1
Kil, M.O.2
Lee, H.3
Kim, S.S.4
Johnson, G.V.5
-
64
-
-
66749167799
-
Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
-
Subramaniam S, Sixt KM, Barrow R, Snyder SH, (2009) Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity. Science 324: 1327-1330.
-
(2009)
Science
, vol.324
, pp. 1327-1330
-
-
Subramaniam, S.1
Sixt, K.M.2
Barrow, R.3
Snyder, S.H.4
-
65
-
-
28844442756
-
Clostridium difficile Toxin A-Induced Colonocyte Apoptosis Involves p53-Dependent p21(WAF1/CIP1) Induction via p38 Mitogen-Activated Protein Kinase
-
Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, et al. (2005) Clostridium difficile Toxin A-Induced Colonocyte Apoptosis Involves p53-Dependent p21(WAF1/CIP1) Induction via p38 Mitogen-Activated Protein Kinase. Gastroenterology 129: 1875-1888.
-
(2005)
Gastroenterology
, vol.129
, pp. 1875-1888
-
-
Kim, H.1
Kokkotou, E.2
Na, X.3
Rhee, S.H.4
Moyer, M.P.5
-
66
-
-
0026076274
-
RNA extracted from paraffin-embedded human tissues is amenable to analysis by PCR amplification
-
Stanta G, Schneider C, (1991) RNA extracted from paraffin-embedded human tissues is amenable to analysis by PCR amplification. Biotechniques 11 (3): 304-308.
-
(1991)
Biotechniques
, vol.11
, Issue.3
, pp. 304-308
-
-
Stanta, G.1
Schneider, C.2
-
67
-
-
0031616454
-
RNA Extraction from Formalin-Fixed and Paraffin-Embedded Tissues
-
Stanta G, Bonin S, Perin R, (1998) RNA Extraction from Formalin-Fixed and Paraffin-Embedded Tissues. Methods in Molecular Biology 86: 23-26.
-
(1998)
Methods in Molecular Biology
, vol.86
, pp. 23-26
-
-
Stanta, G.1
Bonin, S.2
Perin, R.3
-
68
-
-
0038392874
-
A simple method for RNA isolation from formalin-fixed and paraffin-embedded lymphatic tisuues
-
Korbler T, Grskovic M, Dominis M, Antica M, (2003) A simple method for RNA isolation from formalin-fixed and paraffin-embedded lymphatic tisuues. Experimental and Molecular Pathology 74: 336-340.
-
(2003)
Experimental and Molecular Pathology
, vol.74
, pp. 336-340
-
-
Korbler, T.1
Grskovic, M.2
Dominis, M.3
Antica, M.4
-
69
-
-
34447506198
-
Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells
-
Li J, Smyth P, Flavin R, Cahill S, Denning K, et al. (2007) Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol 29: 7-36.
-
(2007)
BMC Biotechnol
, vol.29
, pp. 7-36
-
-
Li, J.1
Smyth, P.2
Flavin, R.3
Cahill, S.4
Denning, K.5
-
70
-
-
42449151984
-
Evaluation and validation of total RNA extraction methods for microRNA expression analyses in formalin-fixed, paraffin-embedded tissues
-
Doleshal M, Magotra AA, Choudhury B, Cannon BD, Labourier E, et al. (2008) Evaluation and validation of total RNA extraction methods for microRNA expression analyses in formalin-fixed, paraffin-embedded tissues. J Mol Diagn 10 (3): 203-211.
-
(2008)
J Mol Diagn
, vol.10
, Issue.3
, pp. 203-211
-
-
Doleshal, M.1
Magotra, A.A.2
Choudhury, B.3
Cannon, B.D.4
Labourier, E.5
-
71
-
-
79958289412
-
MicroRNA Isolation from Formalin-Fixed, Paraffin-Embedded Tissues
-
Liu A, Xu X, (2011) MicroRNA Isolation from Formalin-Fixed, Paraffin-Embedded Tissues. Methods Mol Biol 724: 259-67.
-
(2011)
Methods Mol Biol
, vol.724
, pp. 259-267
-
-
Liu, A.1
Xu, X.2
-
72
-
-
42449098100
-
Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues
-
Peltier HJ, Latham GJ, (2008) Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues. RNA 14: 844-852.
-
(2008)
RNA
, vol.14
, pp. 844-852
-
-
Peltier, H.J.1
Latham, G.J.2
|