In vivo study of the effects of exogenous hydrogen sulfide on lung mitochondria in acute lung injury in rats

BMC Anesthesiology

Volumn 14, Issue 1, 2014, Pages

  Du, Quansheng ^a,b   Wang, Chao ^b   Zhang, Nan ^c   Li, Guofeng ^d   Zhang, Meng ^a   Li, Liping ^d   Zhang, Qingzeng ^d   Zhang, Jianxin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI GENERAL HOSPITAL   (China)

^c Children's Hospital of Hebei Province   (China)

^d Institute of Viral Disease   (China)

Author keywords

Acute lung injury; Exogenous hydrogen sulfide; Lipopolysaccharide; Mitochondria; Mitochondrial lipid peroxidation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYTOCHROME C; GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; MALONALDEHYDE; PROTECTIVE AGENT; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SODIUM HYDROSULFIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE; SODIUM BISULFIDE; SULFIDE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VIVO STUDY; LIPID PEROXIDATION; LOW DRUG DOSE; LUNG MITOCHONDRION; LUNG WEIGHT; MALE; MITOCHONDRION; MITOCHONDRION SWELLING; NONHUMAN; ORGANELLE SHAPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; WESTERN BLOTTING; ANIMAL; BLOOD; CYTOSOL; DISEASE MODEL; DRUG EFFECTS; LUNG; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACUTE LUNG INJURY; ANIMALS; CYTOCHROMES C; CYTOSOL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-1BETA; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MALONDIALDEHYDE; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; SULFIDES; SUPEROXIDE DISMUTASE;

EID: 84965187859     PISSN: None     EISSN: 14712253     Source Type: Journal    
DOI: 10.1186/1471-2253-14-117     Document Type: Article

References (49)

1. Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med 2000, 342:1334-1349.
2. Faller S, Zimmermann KK, Strosing KM: Inhaled hydrogen sulfide protects against lipopolysaccharide-induced acute lung injury in mice. Med Gas Res 2012, 2:2-6.
3. Fried E, Weissman C, Sprung C: Postoperative sepsis. Curr Opin Crit Care 2011, 17:396-401.
4. Huang XL, Ma HJ, Zhou XH: Effect of exogenous hydrogen sulfide on polymorphonuclear neutrophil accumulation in acute lung injury rat induced by lipopolysaccharides and its mechanism. Chin J Appl Physiol 2010, 26:477-480.
5. Fujita M, Kuwano K, Kunitake R, Haqimoto N, Miyazaki H, Kawasaki M, Kawasaki M, Maeyama T, Hara N: Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice. Int Arch Allergy Immunol 1998, 117:202-208.
6. Liaudet L, Rosenblatt-Velin N, Pacher: Role of peroxynitrite in the cardiovascular dysfunction of septic shock. Curr Vasc Pharmacol 2013, 11:196-207.
7. Fielhaber JA, Carroll SF, Dydensborg AB, Shourian M, Triantafillopoulos A, Harel S, Hussain SN, Bouchard M, Qureshi ST, Kristof AS: Inhibition of Mammalian Target of Rapamycin Augments Lipopolysaccharide-Induced Lung Injury and Apoptosis. J Immunol 2012, 188:4535-4542.
8. Liu G, Cheresh P, Kamp DW: Molecular basis of asbestos-induced lung disease. Annu Rev Patho 2013, 24:161-187.
9. Ufnal M, Zera T: The role of nitric oxide, hydrogen sulfide and carbon monoxide in the regulation of the circulatory system and their pharmacotherapeutic potential. Kardiol Pol 2010, 68(Suppl 5):S436-S440.
10. 2S) -the third gas of interest for pharmacologists. Pharmacol Rep 2007, 59:4-24.
11. Wallace JL, Ferraz JG, Muscara MN: Hydrogen sulfide: an endogenous mediator of resolution of inflammation and injury. Antioxid Redox Signal 2012, 17:58-67.
12. Yu YP, Chin XL, Liu LJ: A Hypothesis: Hydrogen Sulfide Might Be Neuroprotective against Subarachnoid Hemorrhage Induced Brain Injury. Sci World J 2014, 2014:432318.
13. Zivkovic V, Jakovljevic V, Pechanova O, Srejovic I, Joksimovic J, Selakovic D, Barudzic N, Djuric DM: Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters. Biomed Res Int 2013, 2013:318-471.
14. Ang AD, Rivers-Auty J, Hegde A, Ishii I, Bhatia M: The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse. Am J Physiol Gastrointest Liver Physiol 2013, 305:G712-G721.
15. Shanmugam MK, Bhatia M: The role of pro-inflammatory molecules and pharmacological agents in acute pancreatitis and sepsis. Inflamm Allergy Drug Targets 2010, 9:20-31.
16. Biermann J, Lagreze WA, Schallner N, Schwer CI, Goebel U: Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury. Mol Vis 2011, 17:1275-1286.
17. Faller S, Ryter SW, Choi AM, Loop T, Schmidt R, Hoetzel A: Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology 2010, 113:104-115.
18. Wang C, Wang HY, Liu ZW, Fu Y, Zhao B: Effect of endogenous hydrogen sulfide on oxidative stress in oleic acid-induced acute lung injury in rats. Chin Med J (Engl) 2011, 124:3476-3480.
19. Faller S, Spassov SG, Zimmermann KK, Ryter SW, Buerkle H, Loop T, Schmidt R, Strosing KM, Hoetzel A: Hydrogen sulfide prevents hyperoxia-induced lung injury by downregulating reactive oxygen species formation and angiopoietin-2 release. Curr Pharm Des 2013, 19:2715-2721.
20. Otulakowski G, Kavanagh BP: Hydrogen Sulfide in Lung Injury Therapeutic Hope from a Toxic Gas? Anesthesiology 2010, 113:4-6.
21. Bhatia M: Role of hydrogen sulfide in the pathology of inflammation. Scientifica (Cairo) 2012, 2012:159680.
22. Smith Kendra M, Mrozek Jeanne D, Simonton Susan C, Bing Dennis R, Meyers Pat A, Connett John E, Mammel MC: Prolonged partical liquid ventilation using conventional and high frequency ventilatory techniques: gas exchange and lung pathology in an animal model of respiratory distress syndrome. Crit Care Med 1997, 25:1888-1897.
23. Szapiel SV, Elson NA, Fulmer JD, Hunninghake GW, Crystal RG: Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis 1979, 120:893-899.
24. Siriporn C: Chattipakorn, Savitree Thummasorn, Jantira Sanit, Nipon Chattipakorn: Phosphodiesterase-3 inhibitor (cilostazol) attenuates oxidative stress-induced mitochondrial dysfunction in the heart. J Geriatr Cardiol 2014, 11:151-157.
25. 2+ uptake during simulated ischemia does not affect permeability transition pore opening upon simulated reperfusion. Cardiovasc Res 2006, 71:715-724.
26. The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000, 342:1301-1308.
27. Wheeler AP, Bernard GR: Acute lung injury and acute respiratory distress syndrome: a clinical review. Lancet 2007, 369:1553-1564.
28. Villar J, Blanco J, Añón JM, Santos-Bouza A, Blanch L, Ambrós A, Mosteiro F, Basaldúa S, Fernández RL, Kacmarek RM, ALIEN Network: The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med 2011, 37:1932-1941.
29. Zhang H, Slutsky AS, Vincent JL: Oxygen free radicals in ARDS, septic shock and organ dysfunction. Intensive Care Med 2000, 26:474-476.
30. Choi JS, Lee HS, Seo KH, Na JO, Kim YH, Uh ST, Park CS, Oh MH, Lee SH, Kim YT: The effect of post-treatment N-acetylcysteine in LPS-induced acute lung injury of rats. Tuberc Respir Dis (Seoul) 2012, 73:22-31.
31. Calfee CS, Matthay MA: Nonventilatory treatments for acute lung injury and ARDS. Chest 2007, 131:913-920.
32. O'Grady NP, Preas HL, Pugin J, Fiuza C, Tropea M, Reda D, Banks SM, Suffredini AF: Local inflammatory responses following bronchial endotoxin instillation in humans. Am J Respir Crit Care Med 2001, 163:1591-1598.
33. Ruchko MV, Gorodnya OM, Zuleta A, Pastukh VM, Gillespie MN: The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells. Free Radic Biol Med 2011, 50:1107-1113.
34. Galluzzi L, Kepp O, Kroemer G: Mitochondria: master regulators of danger signaling. Nat Rev Mol Cell Biol 2012, 13:780-788.
35. Osellame LD, Blacker TS, Duchen MR: Cellular and molecular mechanisms of mitochondrial function. Best Pract Res Clin Endocrinol Metab 2012, 26:711-723.
36. Singer M: The role of mitochondrial dysfunction in sepsis-induced multi-organ failure. Virulence 2014, 5:66-72.
37. Dogan SA, Trifunovic A: Modelling mitochondrial dysfunction in mice. Physiol Res 2011, 60:S61-70.
38. Trentadue R, Fiore F, Massaro F, Papa F, Iuso A, Scacco S, Santacroce L, Brienza N: Induction of mitochondrial dysfunction and oxidative stress in human fibroblast cultures exposed to serum from septic patients. Life Sci 2012, 91:237-243.
39. Chouteau JM, Obiako B, Gorodnya OM, Pastukh VM, Ruchko MV, Wright AJ, Wilson GL, Gillespie MN: Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs. Am J Physiol Lung Cell Mol Physiol 2011, 301:L892-898.
40. Lundy CT, Shield JP, Kivvitingen EA, Vinorum OJ, Trimble ER, Morris AA: Acute respiratory distress syndrome in long-chain 3-hydroxyacyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies. J Inherit Metab Dis 2003, 26:537-541.
41. Yin F, Sancheti H, Cadenas E: Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal 2012, 17:1714-1727.
42. Gu ZY, Ling YL, Xu XH, Meng AH, Li SJ: Effect of peroxynitrite on the reactivity of rabbit pulmonary arteriesin vitro. Acta PhysiolSc 2003, 55:469-474.
43. Liu S, Chen JF: Strategies for therapeutic hypometabothermia. J Exp Stroke Transl Med 2012, 5:31-42.
44. +ATP channel activation. Am J Respir Crit Care Med 2010, 182:360-368.
45. Tokuda K, Kida K, Marutani E, Crimi E, Bougaki M, Khatri A, Kimura H, Ichinose F: Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice. Antioxid Redox Signal 2012, 17:11-21.
46. Aslami H, Pulskens WP, Kuipers MT, Bos AP, van Kuilenburg ABP, Wanders RJ, Roelofsen J, Roelofs JJ, Kerindongo RP, Beurskens CJ, Schultz MJ, Kulik W, Weber NC, Juffermans NP: Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status. PLoS One 2013, 8:e63497.
47. Zhang H, Zhi L, Moore PK, Bhatia M: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol 2006, 290:L1193-L1201.
48. Zhang H, Hegde A, Ng SW, Adhikari S, Moochhala SM, Bhatia M: Hydrogen sulfide up-regulates substance P in polymicrobial sepsis-associated lung injury. J Immunol 2007, 179:4153-4160.
49. Madurga A, Mižíková I, Ruiz-Camp J, Vadász I, Herold S, Mayer K, Fehrenbach H, Seeger W, Morty RE: Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2014, 306:L684-97.