Toll-like Receptor 4 Signaling on Dendritic Cells Suppresses Polymorphonuclear Leukocyte CXCR2 Expression and Trafficking via Interleukin 10 during Intra-abdominal Sepsis

Journal of Infectious Diseases

Volumn 213, Issue 8, 2016, Pages 1280-1288

  Deng, Meihong ^a   Ma, Tao ^c   Yan, Zhengzheng ^d   Zettel, Kent R ^a   Scott, Melanie J ^a   Liao, Hong ^a   Frank, Alicia ^a   Morelli, Adrian E ^a   Sodhi, Chhinder P ^b   Hackam, David J ^b   Billiar, Timothy R ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b JOHNS HOPKINS CHILDREN S CENTER   (United States)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

CLP; CXCR2; dendritic cell; IL 10; PMN recruitment; sepsis; TLR4

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL LOAD; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE SEVERITY; ESCHERICHIA COLI; IN VITRO STUDY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SEPSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; ABDOMINAL INFECTION; ANIMAL; C57BL MOUSE; DISEASE MODEL; IMMUNOLOGY; METABOLISM;

ANIMALS; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; INTERLEUKIN-10; INTRAABDOMINAL INFECTIONS; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, INTERLEUKIN-8B; SEPSIS; TOLL-LIKE RECEPTOR 4;

EID: 84965179453     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv562     Document Type: Article

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