메뉴 건너뛰기




Volumn 173, Issue 12, 2016, Pages 1911-1924

Present and future pharmacotherapeutic agents in heart failure: An evolving paradigm

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CANDESARTAN; CAPTOPRIL; CARDIAC GLYCOSIDE; CARVEDILOL; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENALAPRIL; ENKEPHALINASE INHIBITOR; EPLERENONE; ETOMOXIR; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; IVABRADINE; LOOP DIURETIC AGENT; METOPROLOL; MINERALOCORTICOID ANTAGONIST; NEBIVOLOL; NITRITE; OMAPATRILAT; PERHEXILINE; RAMIPRIL; RANOLAZINE; SACUBITRIL PLUS VALSARTAN; SPIRONOLACTONE; TRIMETAZIDINE; UNINDEXED DRUG; VALSARTAN; CARDIOVASCULAR AGENT;

EID: 84965162741     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13480     Document Type: Review
Times cited : (13)

References (120)
  • 1
    • 78049509377 scopus 로고    scopus 로고
    • Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy
    • Abozguia K, Elliott P, Mckenna W, Phan TT, Nallur-Shivu G, Ahmed I, et al., (2010). Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy. Circulation 122: 1562-1569.
    • (2010) Circulation , vol.122 , pp. 1562-1569
    • Abozguia, K.1    Elliott, P.2    McKenna, W.3    Phan, T.T.4    Nallur-Shivu, G.5    Ahmed, I.6
  • 2
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators
    • AIRE Study Group
    • AIRE Study Group (1993). Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Lancet 342: 821-828.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 8
    • 84908703190 scopus 로고    scopus 로고
    • Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation
    • Bailey JC, Feelisch M, Horowitz JD, Frenneaux MP, Madhani M, (2014). Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation. Pharmacol Ther 144: 303-320.
    • (2014) Pharmacol Ther , vol.144 , pp. 303-320
    • Bailey, J.C.1    Feelisch, M.2    Horowitz, J.D.3    Frenneaux, M.P.4    Madhani, M.5
  • 9
    • 70350094707 scopus 로고    scopus 로고
    • Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans
    • Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, et al., (2009). Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol 107: 1144-1155.
    • (2009) J Appl Physiol , vol.107 , pp. 1144-1155
    • Bailey, S.J.1    Winyard, P.2    Vanhatalo, A.3    Blackwell, J.R.4    Dimenna, F.J.5    Wilkerson, D.P.6
  • 11
    • 77951909696 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy in myocardial disease
    • Beadle R, Frenneaux M, (2010). Magnetic resonance spectroscopy in myocardial disease. Expert Rev Cardiovasc Ther 8: 269-277.
    • (2010) Expert Rev Cardiovasc Ther , vol.8 , pp. 269-277
    • Beadle, R.1    Frenneaux, M.2
  • 12
    • 0034649248 scopus 로고    scopus 로고
    • Congestive heart failure: Fifty years of progress
    • Braunwald E, Bristow MR, (2000). Congestive heart failure: fifty years of progress. Circulation 102: IV14-IV23.
    • (2000) Circulation , vol.102 , pp. IV14-IV23
    • Braunwald, E.1    Bristow, M.R.2
  • 13
    • 0032515917 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors
    • Brown NJ, Vaughan DE, (1998). Angiotensin-converting enzyme inhibitors. Circulation 97: 1411-1420.
    • (1998) Circulation , vol.97 , pp. 1411-1420
    • Brown, N.J.1    Vaughan, D.E.2
  • 14
    • 84866929338 scopus 로고    scopus 로고
    • Redox signaling in cardiac physiology and pathology
    • Burgoyne JR, Mongue-Din H, Eaton P, Shah AM, (2012). Redox signaling in cardiac physiology and pathology. Circ Res 111: 1091-1106.
    • (2012) Circ Res , vol.111 , pp. 1091-1106
    • Burgoyne, J.R.1    Mongue-Din, H.2    Eaton, P.3    Shah, A.M.4
  • 15
    • 0348129532 scopus 로고    scopus 로고
    • Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: A randomized controlled trial
    • Chaitman BR, Pepine CJ, Parker JO, Skopal J, Chumakova G, Kuch J, et al., (2004). Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA 291: 309-316.
    • (2004) JAMA , vol.291 , pp. 309-316
    • Chaitman, B.R.1    Pepine, C.J.2    Parker, J.O.3    Skopal, J.4    Chumakova, G.5    Kuch, J.6
  • 16
    • 84873350548 scopus 로고    scopus 로고
    • Benefits of beta blockers in patients with heart failure and reduced ejection fraction: Network meta-analysis
    • Chatterjee S, Biondi-Zoccai G, Abbate A, D'ascenzo F, Castagno D, Van Tassell B, et al., (2013). Benefits of beta blockers in patients with heart failure and reduced ejection fraction: network meta-analysis. BMJ 346: f55.
    • (2013) BMJ , vol.346 , pp. f55
    • Chatterjee, S.1    Biondi-Zoccai, G.2    Abbate, A.3    D'Ascenzo, F.4    Castagno, D.5    Van Tassell, B.6
  • 17
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: Results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
    • Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT, (2003). Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation 107: 3133-3140.
    • (2003) Circulation , vol.107 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 18
    • 0033514046 scopus 로고    scopus 로고
    • The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial
    • CIBIS-II Study Group
    • CIBIS-II Study Group (1999). The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet 353: 9-13.
    • (1999) Lancet , vol.353 , pp. 9-13
  • 20
  • 21
    • 0022623381 scopus 로고
    • Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study
    • Cohn JN, Archibald DG, Ziesche S, Franciosa JA, Harston WE, Tristani FE, et al., (1986). Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study. N Engl J Med 314: 1547-1552.
    • (1986) N Engl J Med , vol.314 , pp. 1547-1552
    • Cohn, J.N.1    Archibald, D.G.2    Ziesche, S.3    Franciosa, J.A.4    Harston, W.E.5    Tristani, F.E.6
  • 22
    • 0025770138 scopus 로고
    • A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • Cohn JN, Johnson G, Ziesche S, Cobb F, Francis G, Tristani F, et al., (1991). A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325: 303-310.
    • (1991) N Engl J Med , vol.325 , pp. 303-310
    • Cohn, J.N.1    Johnson, G.2    Ziesche, S.3    Cobb, F.4    Francis, G.5    Tristani, F.6
  • 23
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • Cohn JN, Tognoni G, (2001). A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345: 1667-1675.
    • (2001) N Engl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 24
    • 85019316271 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • CONSENSUS Trial Study Group
    • CONSENSUS Trial Study Group (1987). Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 316: 1429-1435.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435
  • 25
    • 0026000171 scopus 로고
    • Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy
    • Conway MA, Allis J, Ouwerkerk R, Niioka T, Rajagopalan B, Radda GK, (1991). Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy. Lancet 338: 973-976.
    • (1991) Lancet , vol.338 , pp. 973-976
    • Conway, M.A.1    Allis, J.2    Ouwerkerk, R.3    Niioka, T.4    Rajagopalan, B.5    Radda, G.K.6
  • 26
    • 0024039574 scopus 로고
    • Pathophysiologic and pharmacotherapy considerations in the management of the black hypertensive patient
    • Cook CA, (1988). Pathophysiologic and pharmacotherapy considerations in the management of the black hypertensive patient. Am Heart J 116: 288-295.
    • (1988) Am Heart J , vol.116 , pp. 288-295
    • Cook, C.A.1
  • 27
    • 84887454400 scopus 로고    scopus 로고
    • Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides
    • Dai DF, Hsieh EJ, Chen T, Menendez LG, Basisty NB, Tsai L, et al., (2013). Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides. Circ Heart Fail 6: 1067-1076.
    • (2013) Circ Heart Fail , vol.6 , pp. 1067-1076
    • Dai, D.F.1    Hsieh, E.J.2    Chen, T.3    Menendez, L.G.4    Basisty, N.B.5    Tsai, L.6
  • 28
    • 0031051347 scopus 로고    scopus 로고
    • The effect of digoxin on mortality and morbidity in patients with heart failure
    • Digitalis Investigation Group
    • Digitalis Investigation Group (1997). The effect of digoxin on mortality and morbidity in patients with heart failure. N Engl J Med 336: 525-533.
    • (1997) N Engl J Med , vol.336 , pp. 525-533
  • 29
    • 84883562084 scopus 로고    scopus 로고
    • Cardiac metabolism in heart failure: Implications beyond ATP production
    • Doenst T, Nguyen TD, Abel ED, (2013). Cardiac metabolism in heart failure: implications beyond ATP production. Circ Res 113: 709-724.
    • (2013) Circ Res , vol.113 , pp. 709-724
    • Doenst, T.1    Nguyen, T.D.2    Abel, E.D.3
  • 30
    • 0025296503 scopus 로고
    • Emerging role of the tissue renin-angiotensin systems in congestive heart failure
    • Dzau VJ, Hirsch AT, (1990). Emerging role of the tissue renin-angiotensin systems in congestive heart failure. Eur Heart J 11 (Suppl B): 65-71.
    • (1990) Eur Heart J , vol.11 , pp. 65-71
    • Dzau, V.J.1    Hirsch, A.T.2
  • 31
    • 0028010788 scopus 로고
    • Tissue angiotensin system in cardiovascular medicine. A paradigm shift?
    • Dzau VJ, Re R, (1994). Tissue angiotensin system in cardiovascular medicine. A paradigm shift? Circulation 89: 493-498.
    • (1994) Circulation , vol.89 , pp. 493-498
    • Dzau, V.J.1    Re, R.2
  • 32
    • 0036174131 scopus 로고    scopus 로고
    • Current evidence supporting the role of diuretics in heart failure: A meta analysis of randomised controlled trials
    • Faris R, Flather M, Purcell H, Henein M, Poole-Wilson P, Coats A, (2002). Current evidence supporting the role of diuretics in heart failure: a meta analysis of randomised controlled trials. Int J Cardiol 82: 149-158.
    • (2002) Int J Cardiol , vol.82 , pp. 149-158
    • Faris, R.1    Flather, M.2    Purcell, H.3    Henein, M.4    Poole-Wilson, P.5    Coats, A.6
  • 33
    • 13544258730 scopus 로고    scopus 로고
    • Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS)
    • Flather MD, Shibata MC, Coats AJ, Van Veldhuisen DJ, Parkhomenko A, Borbola J, et al., (2005). Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS). Eur Heart J 26: 215-225.
    • (2005) Eur Heart J , vol.26 , pp. 215-225
    • Flather, M.D.1    Shibata, M.C.2    Coats, A.J.3    Van Veldhuisen, D.J.4    Parkhomenko, A.5    Borbola, J.6
  • 34
    • 0032212274 scopus 로고    scopus 로고
    • Etiology and response to drug treatment in heart failure
    • Follath F, Cleland JG, Klein W, Murphy R, (1998). Etiology and response to drug treatment in heart failure. J Am Coll Cardiol 32: 1167-1172.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1167-1172
    • Follath, F.1    Cleland, J.G.2    Klein, W.3    Murphy, R.4
  • 36
    • 84907424112 scopus 로고    scopus 로고
    • Ivabradine in stable coronary artery disease without clinical heart failure
    • Fox K, Ford I, Steg PG, Tardif JC, Tendera M, Ferrari R, (2014). Ivabradine in stable coronary artery disease without clinical heart failure. N Engl J Med 371: 1091-1099.
    • (2014) N Engl J Med , vol.371 , pp. 1091-1099
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tardif, J.C.4    Tendera, M.5    Ferrari, R.6
  • 37
    • 50649109186 scopus 로고    scopus 로고
    • Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): A randomised, double-blind, placebo-controlled trial
    • Fox K, Ford I, Steg PG, Tendera M, Ferrari R, (2008). Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet 372: 807-816.
    • (2008) Lancet , vol.372 , pp. 807-816
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tendera, M.4    Ferrari, R.5
  • 38
    • 33747887613 scopus 로고    scopus 로고
    • A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure
    • Fragasso G, Palloshi A, Puccetti P, Silipigni C, Rossodivita A, Pala M, et al., (2006). A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure. J Am Coll Cardiol 48: 992-998.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 992-998
    • Fragasso, G.1    Palloshi, A.2    Puccetti, P.3    Silipigni, C.4    Rossodivita, A.5    Pala, M.6
  • 39
    • 0021829069 scopus 로고
    • Effect of vasodilators on survival in chronic congestive heart failure
    • Furberg CD, Yusuf S, (1985). Effect of vasodilators on survival in chronic congestive heart failure. Am J Cardiol 55: 1110-1113.
    • (1985) Am J Cardiol , vol.55 , pp. 1110-1113
    • Furberg, C.D.1    Yusuf, S.2
  • 40
    • 84949489402 scopus 로고    scopus 로고
    • Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients with Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial
    • Gheorghiade M, Greene SJ, Butler J, Filippatos G, Lam CS, Maggioni AP, et al., (2015). Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial. JAMA 314: 2251-2262.
    • (2015) JAMA , vol.314 , pp. 2251-2262
    • Gheorghiade, M.1    Greene, S.J.2    Butler, J.3    Filippatos, G.4    Lam, C.S.5    Maggioni, A.P.6
  • 41
    • 53449085187 scopus 로고    scopus 로고
    • The functional nitrite reductase activity of the heme-globins
    • Gladwin MT, Kim-Shapiro DB, (2008). The functional nitrite reductase activity of the heme-globins. Blood 112: 2636-2647.
    • (2008) Blood , vol.112 , pp. 2636-2647
    • Gladwin, M.T.1    Kim-Shapiro, D.B.2
  • 42
    • 5444228319 scopus 로고    scopus 로고
    • Regulation of mitochondrial proliferation in the heart: Power-plant failure contributes to cardiac failure in hypertrophy
    • Goffart S, Von Kleist-Retzow JC, Wiesner RJ, (2004). Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy. Cardiovasc Res 64: 198-207.
    • (2004) Cardiovasc Res , vol.64 , pp. 198-207
    • Goffart, S.1    Von Kleist-Retzow, J.C.2    Wiesner, R.J.3
  • 43
    • 0041909380 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARM-Alternative trial
    • Granger CB, Mcmurray JJ, Yusuf S, Held P, Michelson EL, Olofsson B, et al., (2003). Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet 362: 772-776.
    • (2003) Lancet , vol.362 , pp. 772-776
    • Granger, C.B.1    McMurray, J.J.2    Yusuf, S.3    Held, P.4    Michelson, E.L.5    Olofsson, B.6
  • 44
    • 84920265115 scopus 로고    scopus 로고
    • Safety and tolerability of omecamtiv mecarbil during exercise in patients with ischemic cardiomyopathy and angina
    • Greenberg BH, Chou W, Saikali KG, Escandon R, Lee JH, Chen MM, et al., (2015). Safety and tolerability of omecamtiv mecarbil during exercise in patients with ischemic cardiomyopathy and angina. JACC Heart Fail 3: 22-29.
    • (2015) JACC Heart Fail , vol.3 , pp. 22-29
    • Greenberg, B.H.1    Chou, W.2    Saikali, K.G.3    Escandon, R.4    Lee, J.H.5    Chen, M.M.6
  • 45
    • 78049236623 scopus 로고    scopus 로고
    • Clinical use of phosphodiesterase-5 inhibitors in chronic heart failure
    • Guazzi M, (2008). Clinical use of phosphodiesterase-5 inhibitors in chronic heart failure. Circ Heart Fail 1: 272-280.
    • (2008) Circ Heart Fail , vol.1 , pp. 272-280
    • Guazzi, M.1
  • 46
    • 36148948551 scopus 로고    scopus 로고
    • Long-term use of sildenafil in the therapeutic management of heart failure
    • Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD, (2007). Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol 50: 2136-2144.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 2136-2144
    • Guazzi, M.1    Samaja, M.2    Arena, R.3    Vicenzi, M.4    Guazzi, M.D.5
  • 47
    • 64549091508 scopus 로고    scopus 로고
    • Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
    • Heymans S, Hirsch E, Anker SD, Aukrust P, Balligand JL, Cohen-Tervaert JW, et al., (2009). Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 11: 119-129.
    • (2009) Eur J Heart Fail , vol.11 , pp. 119-129
    • Heymans, S.1    Hirsch, E.2    Anker, S.D.3    Aukrust, P.4    Balligand, J.L.5    Cohen-Tervaert, J.W.6
  • 48
    • 34548154261 scopus 로고    scopus 로고
    • Prognosis of all-cause heart failure and borderline left ventricular systolic dysfunction: 5 year mortality follow-up of the Echocardiographic Heart of England Screening Study (ECHOES)
    • Hobbs FD, Roalfe AK, Davis RC, Davies MK, Hare R, (2007). Prognosis of all-cause heart failure and borderline left ventricular systolic dysfunction: 5 year mortality follow-up of the Echocardiographic Heart of England Screening Study (ECHOES). Eur Heart J 28: 1128-1134.
    • (2007) Eur Heart J , vol.28 , pp. 1128-1134
    • Hobbs, F.D.1    Roalfe, A.K.2    Davis, R.C.3    Davies, M.K.4    Hare, R.5
  • 49
    • 34547800233 scopus 로고    scopus 로고
    • A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: The ERGO (etomoxir for the recovery of glucose oxidation) study
    • Holubarsch CJ, Rohrbach M, Karrasch M, Boehm E, Polonski L, Ponikowski P, et al., (2007). A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: the ERGO (etomoxir for the recovery of glucose oxidation) study. Clin Sci (Lond) 113: 205-212.
    • (2007) Clin Sci (Lond) , vol.113 , pp. 205-212
    • Holubarsch, C.J.1    Rohrbach, M.2    Karrasch, M.3    Boehm, E.4    Polonski, L.5    Ponikowski, P.6
  • 50
    • 78049523015 scopus 로고    scopus 로고
    • Perhexiline and hypertrophic cardiomyopathy: A new horizon for metabolic modulation
    • Horowitz JD, Chirkov YY, (2010). Perhexiline and hypertrophic cardiomyopathy: a new horizon for metabolic modulation. Circulation 122: 1547-1549.
    • (2010) Circulation , vol.122 , pp. 1547-1549
    • Horowitz, J.D.1    Chirkov, Y.Y.2
  • 51
    • 0022451358 scopus 로고
    • Perhexiline maleate treatment for severe angina pectoris-correlations with pharmacokinetics
    • Horowitz JD, Sia ST, Macdonald PS, Goble AJ, Louis WJ, (1986). Perhexiline maleate treatment for severe angina pectoris-correlations with pharmacokinetics. Int J Cardiol 13: 219-229.
    • (1986) Int J Cardiol , vol.13 , pp. 219-229
    • Horowitz, J.D.1    Sia, S.T.2    Macdonald, P.S.3    Goble, A.J.4    Louis, W.J.5
  • 52
    • 0034678082 scopus 로고    scopus 로고
    • The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
    • Kantor PF, Lucien A, Kozak R, Lopaschuk GD, (2000). The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 86: 580-588.
    • (2000) Circ Res , vol.86 , pp. 580-588
    • Kantor, P.F.1    Lucien, A.2    Kozak, R.3    Lopaschuk, G.D.4
  • 53
    • 84899424432 scopus 로고    scopus 로고
    • Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health
    • Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A, (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide 38: 45-57.
    • (2014) Nitric Oxide , vol.38 , pp. 45-57
    • Kapil, V.1    Weitzberg, E.2    Lundberg, J.O.3    Ahluwalia, A.4
  • 54
    • 77954743140 scopus 로고    scopus 로고
    • Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure
    • Kato T, Niizuma S, Inuzuka Y, Kawashima T, Okuda J, Tamaki Y, et al., (2010). Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure. Circ Heart Fail 3: 420-430.
    • (2010) Circ Heart Fail , vol.3 , pp. 420-430
    • Kato, T.1    Niizuma, S.2    Inuzuka, Y.3    Kawashima, T.4    Okuda, J.5    Tamaki, Y.6
  • 55
    • 0031756448 scopus 로고    scopus 로고
    • Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart
    • Kennedy JA, Horowitz JD, (1998). Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart. Cardiovasc Drugs Ther 12: 359-363.
    • (1998) Cardiovasc Drugs Ther , vol.12 , pp. 359-363
    • Kennedy, J.A.1    Horowitz, J.D.2
  • 56
    • 0030602865 scopus 로고    scopus 로고
    • Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone
    • Kennedy JA, Unger SA, Horowitz JD, (1996). Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone. Biochem Pharmacol 52: 273-280.
    • (1996) Biochem Pharmacol , vol.52 , pp. 273-280
    • Kennedy, J.A.1    Unger, S.A.2    Horowitz, J.D.3
  • 57
    • 1642452758 scopus 로고    scopus 로고
    • Omapatrilat and enalapril in patients with hypertension: The Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial
    • Kostis JB, Packer M, Black HR, Schmieder R, Henry D, Levy E, (2004). Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial. Am J Hypertens 17: 103-111.
    • (2004) Am J Hypertens , vol.17 , pp. 103-111
    • Kostis, J.B.1    Packer, M.2    Black, H.R.3    Schmieder, R.4    Henry, D.5    Levy, E.6
  • 59
    • 33644875657 scopus 로고    scopus 로고
    • Metabolic modulation with perhexiline in chronic heart failure: A randomized, controlled trial of short-term use of a novel treatment
    • Lee L, Campbell R, Scheuermann-Freestone M, Taylor R, Gunaruwan P, Williams L, et al., (2005). Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment. Circulation 112: 3280-3288.
    • (2005) Circulation , vol.112 , pp. 3280-3288
    • Lee, L.1    Campbell, R.2    Scheuermann-Freestone, M.3    Taylor, R.4    Gunaruwan, P.5    Williams, L.6
  • 60
    • 0037080923 scopus 로고    scopus 로고
    • Metabolic modulation: A means to mend a broken heart
    • Lopaschuk GD, Rebeyka IM, Allard MF, (2002). Metabolic modulation: a means to mend a broken heart. Circulation 105: 140-142.
    • (2002) Circulation , vol.105 , pp. 140-142
    • Lopaschuk, G.D.1    Rebeyka, I.M.2    Allard, M.F.3
  • 61
    • 64249101080 scopus 로고    scopus 로고
    • Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates
    • Luiken JJ, Niessen HE, Coort SL, Hoebers N, Coumans WA, Schwenk RW, et al., (2009). Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates. Biochem J 419: 447-455.
    • (2009) Biochem J , vol.419 , pp. 447-455
    • Luiken, J.J.1    Niessen, H.E.2    Coort, S.L.3    Hoebers, N.4    Coumans, W.A.5    Schwenk, R.W.6
  • 62
    • 38849162730 scopus 로고    scopus 로고
    • The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
    • Lundberg JO, Weitzberg E, Gladwin MT, (2008). The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 7: 156-167.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 156-167
    • Lundberg, J.O.1    Weitzberg, E.2    Gladwin, M.T.3
  • 64
    • 84876400116 scopus 로고    scopus 로고
    • RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: The RALI-DHF proof-of-concept study
    • Maier LS, Layug B, Karwatowska-Prokopczuk E, Belardinelli L, Lee S, Sander J, et al., (2013). RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study. JACC Heart Fail 1: 115-122.
    • (2013) JACC Heart Fail , vol.1 , pp. 115-122
    • Maier, L.S.1    Layug, B.2    Karwatowska-Prokopczuk, E.3    Belardinelli, L.4    Lee, S.5    Sander, J.6
  • 65
    • 84930694859 scopus 로고    scopus 로고
    • Left ventricular assist devices: A rapidly evolving alternative to transplant
    • Mancini D, Colombo PC, (2015). Left ventricular assist devices: a rapidly evolving alternative to transplant. J Am Coll Cardiol 65: 2542-2555.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 2542-2555
    • Mancini, D.1    Colombo, P.C.2
  • 66
    • 0026558346 scopus 로고
    • Adrenergic effects on the biology of the adult mammalian cardiocyte
    • Mann DL, Kent RL, Parsons B, Cooper GT, (1992). Adrenergic effects on the biology of the adult mammalian cardiocyte. Circulation 85: 790-804.
    • (1992) Circulation , vol.85 , pp. 790-804
    • Mann, D.L.1    Kent, R.L.2    Parsons, B.3    Cooper, G.T.4
  • 67
    • 11144355760 scopus 로고    scopus 로고
    • Targeted anticytokine therapy in patients with chronic heart failure: Results of the Randomized Etanercept Worldwide Evaluation (RENEWAL)
    • Mann DL, Mcmurray JJ, Packer M, Swedberg K, Borer JS, Colucci WS, et al., (2004). Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL). Circulation 109: 1594-1602.
    • (2004) Circulation , vol.109 , pp. 1594-1602
    • Mann, D.L.1    McMurray, J.J.2    Packer, M.3    Swedberg, K.4    Borer, J.S.5    Colucci, W.S.6
  • 69
    • 0030032681 scopus 로고    scopus 로고
    • Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts
    • Mccormack JG, Barr RL, Wolff AA, Lopaschuk GD, (1996). Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts. Circulation 93: 135-142.
    • (1996) Circulation , vol.93 , pp. 135-142
    • McCormack, J.G.1    Barr, R.L.2    Wolff, A.A.3    Lopaschuk, G.D.4
  • 70
    • 0032948546 scopus 로고    scopus 로고
    • The endopeptidase inhibitor, candoxatril, and its therapeutic potential in the treatment of chronic cardiac failure in man
    • Mcdowell G, Nicholls DP, (1999). The endopeptidase inhibitor, candoxatril, and its therapeutic potential in the treatment of chronic cardiac failure in man. Expert Opin Investig Drugs 8: 79-84.
    • (1999) Expert Opin Investig Drugs , vol.8 , pp. 79-84
    • McDowell, G.1    Nicholls, D.P.2
  • 71
    • 84864493727 scopus 로고    scopus 로고
    • ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC
    • Mcmurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, et al., (2012). ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 33: 1787-1847.
    • (2012) Eur Heart J , vol.33 , pp. 1787-1847
    • McMurray, J.J.1    Adamopoulos, S.2    Anker, S.D.3    Auricchio, A.4    Bohm, M.5    Dickstein, K.6
  • 72
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • Mcmurray JJ, Ostergren J, Swedberg K, Granger CB, Held P, Michelson EL, et al., (2003). Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 362: 767-771.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    Michelson, E.L.6
  • 73
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • Merit-Hf Study Group
    • Merit-Hf Study Group (1999). Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 353: 2001-2007.
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 74
    • 26244465889 scopus 로고    scopus 로고
    • Explaining the phenomenon of nitrate tolerance
    • Munzel T, Daiber A, Mulsch A, (2005). Explaining the phenomenon of nitrate tolerance. Circ Res 97: 618-628.
    • (2005) Circ Res , vol.97 , pp. 618-628
    • Munzel, T.1    Daiber, A.2    Mulsch, A.3
  • 75
    • 0029780286 scopus 로고    scopus 로고
    • Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug
    • Munzel T, Kurz S, Rajagopalan S, Thoenes M, Berrington WR, Thompson JA, et al., (1996). Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug. J Clin Invest 98: 1465-1470.
    • (1996) J Clin Invest , vol.98 , pp. 1465-1470
    • Munzel, T.1    Kurz, S.2    Rajagopalan, S.3    Thoenes, M.4    Berrington, W.R.5    Thompson, J.A.6
  • 76
    • 36849040149 scopus 로고    scopus 로고
    • Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy
    • Neglia D, De Caterina A, Marraccini P, Natali A, Ciardetti M, Vecoli C, et al., (2007). Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 293: H3270-H3278.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H3270-H3278
    • Neglia, D.1    De Caterina, A.2    Marraccini, P.3    Natali, A.4    Ciardetti, M.5    Vecoli, C.6
  • 77
    • 33947239659 scopus 로고    scopus 로고
    • The failing heart-an engine out of fuel
    • Neubauer S, (2007). The failing heart-an engine out of fuel. N Engl J Med 356: 1140-1151.
    • (2007) N Engl J Med , vol.356 , pp. 1140-1151
    • Neubauer, S.1
  • 78
    • 84942861931 scopus 로고    scopus 로고
    • Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients
    • Ormerod JO, Arif S, Mukadam M, Evans JD, Beadle R, Fernandez BO, et al., (2015). Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients. Circ Heart Fail 8: 565-571.
    • (2015) Circ Heart Fail , vol.8 , pp. 565-571
    • Ormerod, J.O.1    Arif, S.2    Mukadam, M.3    Evans, J.D.4    Beadle, R.5    Fernandez, B.O.6
  • 79
    • 0037159310 scopus 로고    scopus 로고
    • Effect of carvedilol on the morbidity of patients with severe chronic heart failure: Results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study
    • Packer M, Fowler MB, Roecker EB, Coats AJ, Katus HA, Krum H, et al., (2002). Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation 106: 2194-2199.
    • (2002) Circulation , vol.106 , pp. 2194-2199
    • Packer, M.1    Fowler, M.B.2    Roecker, E.B.3    Coats, A.J.4    Katus, H.A.5    Krum, H.6
  • 80
    • 84924243546 scopus 로고    scopus 로고
    • Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure
    • Packer M, Mcmurray JJ, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, et al., (2015). Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation 131: 54-61.
    • (2015) Circulation , vol.131 , pp. 54-61
    • Packer, M.1    McMurray, J.J.2    Desai, A.S.3    Gong, J.4    Lefkowitz, M.P.5    Rizkala, A.R.6
  • 81
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • Paul M, Poyan Mehr A, Kreutz R, (2006). Physiology of local renin-angiotensin systems. Physiol Rev 86: 747-803.
    • (2006) Physiol Rev , vol.86 , pp. 747-803
    • Paul, M.1    Poyan Mehr, A.2    Kreutz, R.3
  • 82
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS guide to PHARMACOLOGY: An expert-driven knowledge base of drug targets and their ligands
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al., (2014). The IUPHAR/BPS guide to PHARMACOLOGY: an expert-driven knowledge base of drug targets and their ligands. Nucleic Acids Res 42: D1098-D1106.
    • (2014) Nucleic Acids Res , vol.42 , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 83
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators
    • Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ Jr, Cuddy TE, et al., (1992). Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 327: 669-677.
    • (1992) N Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3    Basta, L.4    Brown, E.J.5    Cuddy, T.E.6
  • 84
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Pfeffer MA, Mcmurray JJ, Velazquez EJ, Rouleau JL, Kober L, Maggioni AP, et al., (2003). Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 349: 1893-1906.
    • (2003) N Engl J Med , vol.349 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.2    Velazquez, E.J.3    Rouleau, J.L.4    Kober, L.5    Maggioni, A.P.6
  • 86
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, et al., (1999). The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341: 709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 87
    • 0037453950 scopus 로고    scopus 로고
    • Association of serum digoxin concentration and outcomes in patients with heart failure
    • Rathore SS, Curtis JP, Wang Y, Bristow MR, Krumholz HM, (2003). Association of serum digoxin concentration and outcomes in patients with heart failure. JAMA 289: 871-878.
    • (2003) JAMA , vol.289 , pp. 871-878
    • Rathore, S.S.1    Curtis, J.P.2    Wang, Y.3    Bristow, M.R.4    Krumholz, H.M.5
  • 88
    • 0034687595 scopus 로고    scopus 로고
    • Plasma cytokine parameters and mortality in patients with chronic heart failure
    • Rauchhaus M, Doehner W, Francis DP, Davos C, Kemp M, Liebenthal C, et al., (2000). Plasma cytokine parameters and mortality in patients with chronic heart failure. Circulation 102: 3060-3067.
    • (2000) Circulation , vol.102 , pp. 3060-3067
    • Rauchhaus, M.1    Doehner, W.2    Francis, D.P.3    Davos, C.4    Kemp, M.5    Liebenthal, C.6
  • 90
    • 0021858357 scopus 로고
    • Catecholamine cardiotoxicity
    • Rona G, (1985). Catecholamine cardiotoxicity. J Mol Cell Cardiol 17: 291-306.
    • (1985) J Mol Cell Cardiol , vol.17 , pp. 291-306
    • Rona, G.1
  • 91
    • 0029800177 scopus 로고    scopus 로고
    • Fatty acid oxidation enzyme gene expression is downregulated in the failing heart
    • Sack MN, Rader TA, Park S, Bastin J, Mccune SA, Kelly DP, (1996). Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation 94: 2837-2842.
    • (1996) Circulation , vol.94 , pp. 2837-2842
    • Sack, M.N.1    Rader, T.A.2    Park, S.3    Bastin, J.4    McCune, S.A.5    Kelly, D.P.6
  • 92
    • 73849141245 scopus 로고    scopus 로고
    • Cardiorenal syndrome in acute decompensated heart failure
    • Sarraf M, Masoumi A, Schrier RW, (2009). Cardiorenal syndrome in acute decompensated heart failure. Clin J Am Soc Nephrol 4: 2013-2026.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 2013-2026
    • Sarraf, M.1    Masoumi, A.2    Schrier, R.W.3
  • 93
    • 0033910352 scopus 로고    scopus 로고
    • First clinical trial with etomoxir in patients with chronic congestive heart failure
    • Schmidt-Schweda S, Holubarsch C, (2000). First clinical trial with etomoxir in patients with chronic congestive heart failure. Clin Sci (Lond) 99: 27-35.
    • (2000) Clin Sci (Lond) , vol.99 , pp. 27-35
    • Schmidt-Schweda, S.1    Holubarsch, C.2
  • 94
    • 2942737365 scopus 로고    scopus 로고
    • The role of uncoupling protein 3 in fatty acid metabolism: Protection against lipotoxicity?
    • Schrauwen P, Hesselink MK, (2004). The role of uncoupling protein 3 in fatty acid metabolism: protection against lipotoxicity? Proc Nutr Soc 63: 287-292.
    • (2004) Proc Nutr Soc , vol.63 , pp. 287-292
    • Schrauwen, P.1    Hesselink, M.K.2
  • 96
    • 80051968584 scopus 로고    scopus 로고
    • In search of new therapeutic targets and strategies for heart failure: Recent advances in basic science
    • Shah AM, Mann DL, (2011). In search of new therapeutic targets and strategies for heart failure: recent advances in basic science. Lancet 378: 704-712.
    • (2011) Lancet , vol.378 , pp. 704-712
    • Shah, A.M.1    Mann, D.L.2
  • 98
    • 84885310573 scopus 로고    scopus 로고
    • Cardiac metabolism in hypertrophy and heart failure: Implications for therapy
    • Siddiqi N, Singh S, Beadle R, Dawson D, Frenneaux M, (2013). Cardiac metabolism in hypertrophy and heart failure: implications for therapy. Heart Fail Rev 18: 595-606.
    • (2013) Heart Fail Rev , vol.18 , pp. 595-606
    • Siddiqi, N.1    Singh, S.2    Beadle, R.3    Dawson, D.4    Frenneaux, M.5
  • 99
    • 84925858793 scopus 로고    scopus 로고
    • Cardiac energetic impairment in heart disease and the potential role of metabolic modulators: A review for clinicians
    • Singh S, Schwarz K, Horowitz J, Frenneaux M, (2014). Cardiac energetic impairment in heart disease and the potential role of metabolic modulators: a review for clinicians. Circ Cardiovasc Genet 7: 720-728.
    • (2014) Circ Cardiovasc Genet , vol.7 , pp. 720-728
    • Singh, S.1    Schwarz, K.2    Horowitz, J.3    Frenneaux, M.4
  • 100
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • SOLVD Investigators
    • SOLVD Investigators (1992). Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 327: 685-691.
    • (1992) N Engl J Med , vol.327 , pp. 685-691
  • 101
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • Stanley WC, Recchia FA, Lopaschuk GD, (2005). Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85: 1093-1129.
    • (2005) Physiol Rev , vol.85 , pp. 1093-1129
    • Stanley, W.C.1    Recchia, F.A.2    Lopaschuk, G.D.3
  • 102
    • 77956612624 scopus 로고    scopus 로고
    • Ivabradine and outcomes in chronic heart failure (SHIFT): A randomised placebo-controlled study
    • Swedberg K, Komajda M, Bohm M, Borer JS, Ford I, Dubost-Brama A, et al., (2010). Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study. Lancet 376: 875-885.
    • (2010) Lancet , vol.376 , pp. 875-885
    • Swedberg, K.1    Komajda, M.2    Bohm, M.3    Borer, J.S.4    Ford, I.5    Dubost-Brama, A.6
  • 103
    • 18244401979 scopus 로고    scopus 로고
    • Combination treatment in stable effort angina using trimetazidine and metoprolol: Results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in Poland
    • Szwed H, Sadowski Z, Elikowski W, Koronkiewicz A, Mamcarz A, Orszulak W, et al., (2001). Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand. Eur Heart J 22: 2267-2274.
    • (2001) Eur Heart J , vol.22 , pp. 2267-2274
    • Szwed, H.1    Sadowski, Z.2    Elikowski, W.3    Koronkiewicz, A.4    Mamcarz, A.5    Orszulak, W.6
  • 104
    • 19644400578 scopus 로고    scopus 로고
    • Combination of isosorbide dinitrate and hydralazine in blacks with heart failure
    • Taylor AL, Ziesche S, Yancy C, Carson P, D'agostino R Jr, Ferdinand K, et al., (2004). Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N Engl J Med 351: 2049-2057.
    • (2004) N Engl J Med , vol.351 , pp. 2049-2057
    • Taylor, A.L.1    Ziesche, S.2    Yancy, C.3    Carson, P.4    D'Agostino, R.5    Ferdinand, K.6
  • 105
    • 77956617171 scopus 로고    scopus 로고
    • Ivabradine in heart failure-no paradigm SHIFT...yet
    • Teerlink JR, (2010). Ivabradine in heart failure-no paradigm SHIFT...yet. Lancet 376: 847-849.
    • (2010) Lancet , vol.376 , pp. 847-849
    • Teerlink, J.R.1
  • 107
    • 38149087638 scopus 로고    scopus 로고
    • Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): A placebo-controlled randomised trial
    • Torre-Amione G, Anker SD, Bourge RC, Colucci WS, Greenberg BH, Hildebrandt P, et al., (2008). Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a placebo-controlled randomised trial. Lancet 371: 228-236.
    • (2008) Lancet , vol.371 , pp. 228-236
    • Torre-Amione, G.1    Anker, S.D.2    Bourge, R.C.3    Colucci, W.S.4    Greenberg, B.H.5    Hildebrandt, P.6
  • 109
    • 0030778603 scopus 로고    scopus 로고
    • Etomoxir improves left ventricular performance of pressure-overloaded rat heart
    • Turcani M, Rupp H, (1997). Etomoxir improves left ventricular performance of pressure-overloaded rat heart. Circulation 96: 3681-3686.
    • (1997) Circulation , vol.96 , pp. 3681-3686
    • Turcani, M.1    Rupp, H.2
  • 110
    • 0030891048 scopus 로고    scopus 로고
    • Perhexiline improves symptomatic status in elderly patients with severe aortic stenosis
    • Unger SA, Robinson MA, Horowitz JD, (1997). Perhexiline improves symptomatic status in elderly patients with severe aortic stenosis. Aust N Z J Med 27: 24-28.
    • (1997) Aust N Z J Med , vol.27 , pp. 24-28
    • Unger, S.A.1    Robinson, M.A.2    Horowitz, J.D.3
  • 111
    • 0033959905 scopus 로고    scopus 로고
    • Cardiac fatty acid uptake and transport in health and disease
    • Van Der Vusse GJ, Van Bilsen M, Glatz JF, (2000). Cardiac fatty acid uptake and transport in health and disease. Cardiovasc Res 45: 279-293.
    • (2000) Cardiovasc Res , vol.45 , pp. 279-293
    • Van Der Vusse, G.J.1    Van Bilsen, M.2    Glatz, J.F.3
  • 113
    • 84926135895 scopus 로고    scopus 로고
    • Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure
    • Vardeny O, Miller R, Solomon SD, (2014). Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure. JACC Heart Fail 2: 663-670.
    • (2014) JACC Heart Fail , vol.2 , pp. 663-670
    • Vardeny, O.1    Miller, R.2    Solomon, S.D.3
  • 114
    • 55449121681 scopus 로고    scopus 로고
    • Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: Role for xanthine oxidoreductase and endothelial nitric oxide synthase
    • Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, et al., (2008). Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase. Circ Res 103: 957-964.
    • (2008) Circ Res , vol.103 , pp. 957-964
    • Webb, A.J.1    Milsom, A.B.2    Rathod, K.S.3    Chu, W.L.4    Qureshi, S.5    Lovell, M.J.6
  • 115
    • 84872680154 scopus 로고    scopus 로고
    • Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome
    • Yin X, Dwyer J, Langley SR, Mayr U, Xing Q, Drozdov I, et al., (2013). Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. J Mol Cell Cardiol 55: 27-30.
    • (2013) J Mol Cell Cardiol , vol.55 , pp. 27-30
    • Yin, X.1    Dwyer, J.2    Langley, S.R.3    Mayr, U.4    Xing, Q.5    Drozdov, I.6
  • 116
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM-preserved trial
    • Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, Mcmurray JJ, et al., (2003). Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-preserved trial. Lancet 362: 777-781.
    • (2003) Lancet , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    McMurray, J.J.6
  • 117
    • 84922367928 scopus 로고    scopus 로고
    • Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction
    • discussion 380
    • Zamani P, Rawat D, Shiva-Kumar P, Geraci S, Bhuva R, Konda P, et al., (2015). Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction. Circulation 131: 371-380; discussion 380.
    • (2015) Circulation , vol.131 , pp. 371-380
    • Zamani, P.1    Rawat, D.2    Shiva-Kumar, P.3    Geraci, S.4    Bhuva, R.5    Konda, P.6
  • 118
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES)
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B, (2000). Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Rales Investig Circ 102: 2700-2706.
    • (2000) Rales Investig Circ , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 120
    • 84863243325 scopus 로고    scopus 로고
    • Additional use of trimetazidine in patients with chronic heart failure: A meta-analysis
    • Zhang L, Lu Y, Jiang H, Zhang L, Sun A, Zou Y, et al., (2012). Additional use of trimetazidine in patients with chronic heart failure: a meta-analysis. J Am Coll Cardiol 59: 913-922.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 913-922
    • Zhang, L.1    Lu, Y.2    Jiang, H.3    Zhang, L.4    Sun, A.5    Zou, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.