Increased free circulating DNA integrity index as a serum biomarker in patients with colorectal carcinoma

Asian Pacific Journal of Cancer Prevention

Volumn 17, Issue 3, 2016, Pages 939-944

  El Gayar, Dina ^a   El Abd, Nevine ^a   Hassan, Noha ^b   Ali, Reem ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

ALU q PCR; CEA CA19 9; Colorectal carcinoma; DNA integrity index

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; DNA; TUMOR MARKER;

ADULT; BLOOD; COLORECTAL TUMOR; FEMALE; HUMAN; MALE; MIDDLE AGED; PATHOLOGY;

ADULT; BIOMARKERS, TUMOR; CA-19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; DNA; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 84965053885     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2016.17.3.939     Document Type: Article

References (23)

1. Agostini M, Pucciarelli M, Vittoria M (2011). Circulating cell-free DNA: a promising marker of pathologic tumor response in rectal cancer patients receiving preoperative chemoradiotherapy. Ann Surg Oncol, 18, 2461-8
2. Casadio V, Foca F, Zingaretti C, et al (2013). Gene methylation in rectal cancer: predictive marker of response to chemoradiotherapy. J Cell Physiol, 228, 2343-9
3. Chen H, Sun LY, Zheng HQ, et al (2012). Total serum DNA and DNA integrity: diagnostic value in patients with hepatitis B virus-related hepatocellular carcinoma. Pathol, 44, 318-24
4. Cordaux R, Batzer MA (2009). The impact of retrotransposons on human genome evolution. Nature Reviews Genetics, 10, 691-703
5. da Silva Filho BF, Gurgel AP, Neto MA, et al (2013). Circulating cell-free DNA in serum as a biomarker of colorectal cancer. J Clin Pathol, 66, 775-8
6. David A, Lieberman D, Douglas K, et al (2012). Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US multi-society task force on colorectal cancer. Gastroentrol, 143, 844-85
7. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al (2013). Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer. 49, 1374-403
8. Fong SL, Zhang JT, Lim CK, et al (2009). Comparison of 7 methods for extracting cell-free DNA from serum samples of colorectal cancer patients. Clin Chem, 55, 587-9
9. Gao YJ, He YJ, Yang ZL (2010). Increased integrity of circulating cell free DNA in plasma of patients with acute leukemia. Clin Chem Lab Med, 48, 1651-6
10. Hanley R, Christ KM, Canes D (2006). DNA integrity assay: a plasma-based screening tool for the detection of prostate cancer. Clin Cancer Res, 12, 4569-74
11. Hao TB, Shi W, Shen XJ2, et al (2014). Circulating cell-free DNA in serum as a biomarker for diagnosis and prognostic prediction of colorectal cancer. Br J Cancer, 111, 1482-9
12. Labianca R, Nordlinger B, Beretta. G, et al (2013). Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol, 24, 64-72
13. Leszinski G, Lehner J, Gezer U, et al (2013). Increased DNA integrity in colorectal cancer. In Vivo, 3, 299-303
14. Luo L, Ting W, Qian H, et al (2014). Changes of TCR repertoire diversity in colorectal cancer after erbitux (cetuximab) in combination with chemotherapy. Am J Cancer Res. 4, 924-33
15. Maestranzi S, Przemioslo R, Mitchell H, et al (1998). The effect of benign and malignant liver disease on the tumor markers CA 19-9 and CEA. Ann Clin Biochem, 35, 99-103
16. Maio G, Rengucci C, Zoli W, et al (2014). Circulating and stool nucleic acid analysis for colorectal cancer diagnosis. World J Gastroenterol, 20, 957-67
17. Mead R, Duku M, Bhandari P, et al (2011). Circulating tumour markers can define patients with normal colons, benign polyps, and cancers. Br J Cancer, 105, 239-45
18. Otero E, Chiara L, Rodríguez L, et al (2015). Serum sCD26 for colorectal cancer screening in family-risk individuals: comparison with fecal immunochemical test. British. J Cancer, 112, 375-81
19. Pinzani P, Salvianti F, Zaccara S (2011). Circulating cell-free DNA in plasma of melanoma patients: qualitative and quantitative considerations. Clin Chim Acta, 412, 2141-5
20. Umetani N, Kim J, Hiramatsu S, et al (2006). Increased integrity of free circulating DNA in sera of patients with colorectal or periampullary cancer: direct quantitative PCR for ALU repeats. Clinical Chemistry, 52, 61062-9
21. Wang H, Nekrutenko A, Li WH (2000). Densities, length proportions, and other distributional features of repetitive sequences in the human genome estimated from 430 megabases of genomic sequence. Gene, 259, 81-8
22. Wang M, Li Y, Wang Z, et al (2015). The PKA RIa/A-kinase anchoring proteins 10 signaling pathway and the prognosis of colorectal cancer. J Gastroenterol Hepatol, 30, 496-503
23. Zaher MN, Mahpar E, Rafiq S, et al (2014). Clinical features and outcome of sporadic colorectal carcinoma in young patients: a cross-sectional analysis from a Developing Country. ISRN Oncol, 2014, 461570