A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits

Neuropsychopharmacology

Volumn 41, Issue 10, 2016, Pages 2512-2520

  Egervari, Gabor ^a   Jutras Aswad, Didier ^a   Landry, Joseph ^a   Miller, Michael L ^a   Anderson, Sarah Ann ^a   Michaelides, Michael ^a   Jacobs, Michelle M ^a   Peter, Cyril ^a   Yiannoulos, Georgia ^a   Liu, Xun ^a   Hurd, Yasmin L ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; MICRORNA; PRODYNORPHIN; 3' UNTRANSLATED REGION; ENKEPHALIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; MIRN365 MICRORNA, MOUSE; PREPROENKEPHALIN; PROTEIN PRECURSOR;

3' UNTRANSLATED REGION; ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; COMPUTER MODEL; CONTROLLED STUDY; DECISION MAKING; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; IN VITRO STUDY; MALE; MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW; NEGATIVE FEEDBACK; NERVE CELL; NERVE CELL CULTURE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NORMAL HUMAN; NUCLEUS ACCUMBENS SHELL; PERSONALITY; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD; RNA BINDING; SINGLE NUCLEOTIDE POLYMORPHISM; STEREOTAXIC SURGERY; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; VENTRAL STRIATONIGRAL NEURON; ANIMAL; CORPUS STRIATUM; CYTOLOGY; EXPLORATORY BEHAVIOR; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; INSTRUMENTAL CONDITIONING; LONG EVANS RAT; METABOLISM; PHYSIOLOGY; SUBSTANTIA NIGRA;

3' UNTRANSLATED REGIONS; ANIMALS; CONDITIONING, OPERANT; CORPUS STRIATUM; DECISION MAKING; ENKEPHALINS; EXPLORATORY BEHAVIOR; GENOTYPE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MALE; MICRORNAS; NEURONS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN PRECURSORS; RATS; RATS, LONG-EVANS; REINFORCEMENT (PSYCHOLOGY); RNA, MESSENGER; SUBSTANTIA NIGRA; TRANSDUCTION, GENETIC; TRANSFECTION;

EID: 84965037288     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2016.53     Document Type: Article

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