Association between VNTR polymorphism in promoter region of prodynorphin (PDYN) gene and heroin dependence

Psychiatry Research

Volumn 219, Issue 3, 2014, Pages 690-692

  Saify, Khyber ^a   Saadat, Iraj ^a   Saadat, Mostafa ^a  

^a SHIRAZ UNIVERSITY   (Iran)

Author keywords

Heroin dependence; PDYN; VNTR

Indexed keywords

DIAMORPHINE; GENOMIC DNA; PRODYNORPHIN; ENKEPHALIN; LEUCINE ENKEPHALIN; PREPROENKEPHALIN; PRO-ENKEPHALIN-LEU; PROTEIN PRECURSOR;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DNA ISOLATION; FEMALE; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HEROIN DEPENDENCE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEIC ACID STRUCTURE; PDYN GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEX DIFFERENCE; VNTR POLYMORPHISM; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; PSYCHOLOGY; VARIABLE NUMBER OF TANDEM REPEAT;

ALLELES; CASE-CONTROL STUDIES; ENKEPHALIN, LEUCINE; ENKEPHALINS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEROIN DEPENDENCE; HUMANS; MALE; MINISATELLITE REPEATS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEIN PRECURSORS;

EID: 84907597924     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2014.06.048     Document Type: Article

References (8)

1. Limosin F, Gorwood P, Loze JY, et al. Male limited association of the dopamine receptor D2 gene TaqI A polymorphism and alcohol dependence. American Journal of Medical Genetics 2002, 112:343-346.
2. Rafiee L, Saadat I, Saadat M Glutathione S-transferase genetic polymorphisms (GSTM1, GSTT1 and GSTO2) in three Iranian populations. Molecular Biology Reports 2010, 37:155-158.
3. Rockman MV, Hahn MW, Soranzo N, et al. Ancient and recent positive selection transformed opioid cis-regulation in humans. PLoS Biology 2005, 3:e387.
4. Rouault M, Nielsen DA, Ho A, et al. Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity. Addiction Biology 2011, 16:334-346.
5. Saadat M, Ansari-Lari M Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures. Breast Cancer Research Treatment 2009, 115:137-144.
6. Schwarzer C 30 years of dynorphins - new insights on their functions in neuropsychiatric diseases. Pharmacology & Therapeutics 2009, 123:353-370.
7. Wei SG, Zhu YS, Lai JH, et al. Association between heroin dependence and prodynorphin gene polymorphisms. Brain Research Bulletin 2011, 85:238-242.
8. Zimprich A, Kraus J, Woltje M, et al. Allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression. Journal of Neurochemistry 2000, 74:472-477.