Neurotoxic effects of gestational exposure of methyl mercury on different brain regions of F1 generation; neurobehavioural, biochemical and histological study during weaning period of rat

International Journal of Toxicological and Pharmacological Research

Volumn 8, Issue 2, 2016, Pages 83-93

  Sherin, J ^a   Sumathi, T ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Cerebellum; Cerebral cortex; Gestational; Hippocampus; Methyl mercury; Oxidative stress response

Indexed keywords

CATALASE; DRINKING WATER; GLUTATHIONE; GLUTATHIONE PEROXIDASE; METHYLMERCURY; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BIRTH; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; FEMALE; FORCED SWIM TEST; GESTATION PERIOD; GLIOSIS; HIPPOCAMPUS; MORRIS WATER MAZE TEST; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; OPEN FIELD TEST; OXIDATIVE STRESS; RAT; ROTAROD TEST;

EID: 84965010244     PISSN: None     EISSN: 09755160     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Jiang GB, Shi JB, Feng XB (2006) Mercury pollution in China. Environmental science and technology 2006; 40: 3672-3678.
2. Mergler D, Anderson HA, Chan LHM et al. Methylmercury exposure and health effects in humans: a worldwide concern. Ambio 2007; 36: 3-11.
3. Kocman, D, Horvat, M, Kotnik, J. Mercury fractionation in contaminated soils from the Idrija mercury mine region. Journal of Environmental Monitoring. 2004; 6: 696-703.
4. Heileen Hsu-Kim, Katarzyna H. Kucharzyk, Tong Zhang, Marc A. Deshusses. Mechanisms regulating mercury bioavailability for methylating microorganisms in the aquatic environment: A critical review. Environ. Sci. Technol. 2013; 47: 2441-2456.
5. Madenjian C. P, O'Connor D. V. Trophic transfer efficiency of mercury to lake whitefish coregonus clupeaformis from its prey. Bull Environ Contam Toxicol. 2008; 81: 566-570.
6. Daniel Cossa, Lars-Eric Heimbürger, Delphine Lannuzel. Mercury in the Southern Ocean. Geochimica et Cosmochimica Acta. 2011; 75: 4037-4052.
7. Kimio Maruyama, Takashi Yorifuji, Toshihide Tsuda, Tomoko Sekikawa, Hiroto Nakadaira, Hisashi Saito. Methyl Mercury Exposure at Niigata, Japan: Results of Neurological Examinations of 103 Adults. Journal of Biomedicine and Biotechnology. 2012; doi: 10. 1155/2012/635075.
8. Harada M. Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. Crit Rev Toxicol. 1995; 25: 1-24.
9. Amin-Zaki L, Elhassani S, Majeed MA, Clarkson TW, Doherty RA, Greenwood M. Intra-uterine methylmercury poisoning in Iraq. Pediatrics. 1974; 54: 587-95.
10. Cheng-Kuan Su, Cheng-Hung Yang, Cheng-Hsing Lin, Yuh-Chang Sun. In-vivo evaluation of the permeability of the blood-brain barrier to arsenicals, molybdate, and methylmercury by use of online microdialysis-packed minicolumn-inductively coupled plasma mass spectrometry. Analytical and Bioanalytical Chemistry. 2014; 406: 239-247.
11. Kajiwara Y, Yasutake A, Adachi T, Hirayama K. Methylmercury transport across the placenta via neutral amino acid carrier. Arch Toxicol. 1996; 70: 310-4.
12. Ceccatelli S, Dare E, Moors M. Methylmercury-induced neurotoxicity and apoptosis. Chem Biol Interact. 2010; 188: 301-308.
13. Clarkson TW, Magos L, Myers GJ. The toxicology of mercury-current exposures and clinical manifestations. N Engl J Med. 2001; 349: 1731-1737.
14. Oken E, Radesky JS, Wright RO, Bellinger DC, Amarasiriwardena CJ, Kleinman KP, Hu H, Gillman MW. Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort. Am J Epidemiol. 2008; 167: 1171-1181.
15. Ali SF, LeBel CP, Bondy SC. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology. 1992; 13: 637-648.
16. Yee S, Choi BH. Oxidative stress in neurotoxic effects of methylmercury poisoning. Neurotoxicology. 1996; 17: 17-26.
17. O'Reilly, Randall C, Rudy, Jerry W. Conjunctive representations in learning and memory: Principles of cortical and hippocampal function. Psychological Review. 2001; 108: 311-345.
18. Catherine J. Stoodley, Jeremy D. Schmahmann. Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing. Cortex. 2010; 46: 831-844.
19. W Singer. Synchronization of Cortical Activity and its Putative Role in Information Processing and Learning. Annual Review of Physiology. 1993; 55: 349-374.
20. Tereza Nekovarova, Jan Nedvidek, Daniel Klement, Jan Bures. Spatial decisions and cognitive strategies of monkeys and humans based on abstract spatial stimuli in rotation test. Proc Natl Acad Sci 2009; 106: 15478-15482.
21. Emily B. Bisen-Hersh, Marcelo Farina, Fernando Barbosa et al. Behavioral Effects of Developmental Methylmercury Drinking Water Exposure in Rodents. J Trace Elem Med Biol 2014; 28: 117-124.
22. Zhang Y, Jiang X, Zhao X et al. Time-course effect and region-specificity of endoplasmic reticulum stress in rat brains acutely exposed by methylmercury. Wei Sheng Yan Jiu 2010; 39: 271-4.
23. Rustay NR, Wahlsten D, Crabbe JC. Influence of task parameters on rotarod performance and sensitivity to ethanol in mice. Behav Brain Res. 2003; 141: 237-49.
24. Hamm RJ, Pike BR, O'Dell DM et al. The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injury. J Neurotrauma. 1994; 11: 187-96.
25. Gandhi D. N, Dhull Dinesh K. Postnatal Behavioural Effects on the Progeny of Rat after Prenatal Exposure to Methylmercury. American Journal of Experimental Biology 2014; 1: 31-51.
26. Beyrouty P, Stamler CJ, Liu JN, Loua KM, Kubow S, Chan HM. Effects of prenatal methylmercury exposure on brain monoamine oxidase activity and neurobehaviour of rats. Neurotoxicol Teratol. 2006; 28: 251-9.
27. Falluel-Morel A, Sokolowski K, Sisti HM et al. Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty. J Neurochem. 2007; 103: 1968-81.
28. Porsolt RD, Bertin A, Jalfre, M. Behavioral despair in mice: A primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977; 229: 327-336.
29. Natalia Onishchenko, Christoffer Tamm, Marie Vahter et al. Developmental exposure to methylmercury alters learning and induces depression-like behavior in male mice. Toxicological sciences. 2007; 97: 428-437.
30. Okhawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979; 95: 351-358.
31. Moron M, Depierre J W, Mannervik BT. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta. 1979; 582: 67-78.
32. Rotruck JT et al. Selenium: biochemical role as a component of GPx. Science. 1973; 179: 588-590.
33. Marklund. S, Marklund, G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J Biochem. 1974; 47: 469-474.
34. Gandhi D. N, Panchal G. M, Dinesh K. Dhull. Influence of gestational exposure on the effects of prenatal exposure to methyl mercury on postnatal development in rats. Cent Eur J Public Health. 2013; 21: 239-243.
35. Harada M. Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. Crit Rev Toxicol. 1995; 25: 1-24.
36. Catherine P. Crameredda Thiels Jeffrey R. Alberts. Weaning in Rats: I. Maternal Behavior Developmental Psychobiology. 1990; 23: 479-493.
37. Seongil Jo, Hae Dong Woo, Ho-Jang Kwon. Estimation of the Biological Half-Life of Methylmercury Using a Population Toxicokinetic Model. Int J Environ Res Public Health. 2015; 12: 9054-9067.
38. Amin-Zaki L, Majeed MA, Elhassani SB, Clarkson TW, Greenwood MR, Doherty RA. Prenatal methylmercury poisoning. Clinical observations over five years. Am J Dis Child. 1979; 133: 172-7.
39. Rossi AD, Ahlbom E, Ogren SO, Nicotera P, Ceccatelli S. Prenatal exposure to methylmercury alters locomotor activity of male but not female rats. Exp Brain Res. 1997; 117: 428-36.
40. Nielsen JB, Andersen O. The toxicokinetics of mercury in mice offspring after maternal exposure to methylmercury-effect of selenomethionine. Toxicology. 1992; 74: 233-41.
41. Mineshi Sakamoto, Koichi Wakabayashi, Akiyoshi Kakita. Widespread neuronal degeneration in rats following oral administration of methylmercury during the postnatal developing phase: a model of fetal-type Minamata disease. Brain Research. 1998; 784: 351-354.
42. Akiyoshi Kakita, Koichi Wakabayashi, Mu Su. Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury Brain Research. 2000; 859: 233-239.
43. Kakita, Akiyoshi MD, Wakabayashi, Koichi MD et al. Experimentally Induced Leptomeningeal Glioneuronal Heterotopia and Underlying Cortical Dysplasia of the Lateral Limbic Area in Rats Treated Transplacentally with Methylmercury. Journal of Neuropathology & Experimental Neurology. 2001; 60: 768-777.
44. Sarvajeet Singh Gill, Narendra Tuteja. Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. Plant Physiology and Biochemistry. 2010; 48: 909-930.
45. John Sushma, S. Priyanka, K. Jayantha Rao. Neuroprotective role of Melatonin against aluminum-induced oxidative stress in the hippocampus of mouse brain. Journal of Applied Pharmaceutical Science. 2011; 10: 126-133.