-
1
-
-
84884368877
-
Influence of tumour micro-environment heterogeneity on therapeutic response
-
Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013;501:346-54.
-
(2013)
Nature
, vol.501
, pp. 346-354
-
-
Junttila, M.R.1
De Sauvage, F.J.2
-
2
-
-
84867121875
-
Intratumor heterogeneity: Evolution through space and time
-
Swanton C. Intratumor heterogeneity: evolution through space and time. Cancer Res 2012;72:4875-82.
-
(2012)
Cancer Res
, vol.72
, pp. 4875-4882
-
-
Swanton, C.1
-
4
-
-
77956491337
-
Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors
-
Hamm CA, Stevens JW, Xie H, Vanin EF, Morcuende JA, Abdulkawy H, et al. Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors. BMC Cancer 2010;10:471.
-
(2010)
BMC Cancer
, vol.10
, pp. 471
-
-
Hamm, C.A.1
Stevens, J.W.2
Xie, H.3
Vanin, E.F.4
Morcuende, J.A.5
Abdulkawy, H.6
-
5
-
-
84901473312
-
Imaging hallmarks of cancer in living mice
-
Ellenbroek SI, van Rheenen J. Imaging hallmarks of cancer in living mice. Nat Rev Cancer 2014;14:406-18.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 406-418
-
-
Ellenbroek, S.I.1
Van Rheenen, J.2
-
6
-
-
84897482887
-
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
-
Cleary AS, Leonard TL, Gestl SA, Gunther EJ. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature 2014;508:113-7.
-
(2014)
Nature
, vol.508
, pp. 113-117
-
-
Cleary, A.S.1
Leonard, T.L.2
Gestl, S.A.3
Gunther, E.J.4
-
7
-
-
77955911497
-
Tumor heterogeneity is an active process maintained by a mutant EGFRinduced cytokine circuit in glioblastoma
-
Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, et al. Tumor heterogeneity is an active process maintained by a mutant EGFRinduced cytokine circuit in glioblastoma. Genes Dev 2010;24:1731-45.
-
(2010)
Genes Dev
, vol.24
, pp. 1731-1745
-
-
Inda, M.M.1
Bonavia, R.2
Mukasa, A.3
Narita, Y.4
Sah, D.W.5
Vandenberg, S.6
-
8
-
-
79751511326
-
A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer
-
Calbo J, van Montfort E, Proost N, van Drunen E, Beverloo HB, Meuwissen R, et al. A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer. Cancer Cell 2011;19:244-56.
-
(2011)
Cancer Cell
, vol.19
, pp. 244-256
-
-
Calbo, J.1
Van Montfort, E.2
Proost, N.3
Van Drunen, E.4
Beverloo, H.B.5
Meuwissen, R.6
-
10
-
-
0141426742
-
Transfer of biologically important molecules between cells through gap junction channels
-
Alexander DB, Goldberg GS. Transfer of biologically important molecules between cells through gap junction channels. Curr Med Chem 2003;10: 2045-58.
-
(2003)
Curr Med Chem
, vol.10
, pp. 2045-2058
-
-
Alexander, D.B.1
Goldberg, G.S.2
-
11
-
-
1142286348
-
Nanotubular highways for intercellular organelle transport
-
Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH. Nanotubular highways for intercellular organelle transport. Science 2004;303:1007-10.
-
(2004)
Science
, vol.303
, pp. 1007-1010
-
-
Rustom, A.1
Saffrich, R.2
Markovic, I.3
Walther, P.4
Gerdes, H.H.5
-
12
-
-
84874377202
-
Extracellular vesicles: Exosomes, microvesicles, and friends
-
Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol 2013;200:373-83.
-
(2013)
J Cell Biol
, vol.200
, pp. 373-383
-
-
Raposo, G.1
Stoorvogel, W.2
-
13
-
-
84936980504
-
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
-
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 2015;523:177-82.
-
(2015)
Nature
, vol.523
, pp. 177-182
-
-
Melo, S.A.1
Luecke, L.B.2
Kahlert, C.3
Fernandez, A.F.4
Gammon, S.T.5
Kaye, J.6
-
14
-
-
0037183242
-
Malignant effusions and immunogenic tumour-derived exosomes
-
Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, et al. Malignant effusions and immunogenic tumour-derived exosomes. Lancet 2002;360:295-305.
-
(2002)
Lancet
, vol.360
, pp. 295-305
-
-
Andre, F.1
Schartz, N.E.2
Movassagh, M.3
Flament, C.4
Pautier, P.5
Morice, P.6
-
15
-
-
34249302620
-
Exosomemediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosomemediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007;9:654-9.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
16
-
-
84860218631
-
Intercellular communication: Diverse structures for exchange of genetic information
-
Mittelbrunn M, Sanchez-Madrid F. Intercellular communication: diverse structures for exchange of genetic information. Nat Rev Mol Cell Biol 2012; 13:328-35.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 328-335
-
-
Mittelbrunn, M.1
Sanchez-Madrid, F.2
-
17
-
-
84903289462
-
Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation
-
Ridder K, Keller S, Dams M, Rupp AK, Schlaudraff J, Del Turco D, et al. Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. PLoS Biol 2014;12:e1001874.
-
(2014)
PLoS Biol
, vol.12
, pp. e1001874
-
-
Ridder, K.1
Keller, S.2
Dams, M.3
Rupp, A.K.4
Schlaudraff, J.5
Del Turco, D.6
-
18
-
-
84944463735
-
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
-
Ridder K, Sevko A, Heide J, Dams M, Rupp AK, Macas J, et al. Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology 2015;4:e1008371.
-
(2015)
Oncoimmunology
, vol.4
, pp. e1008371
-
-
Ridder, K.1
Sevko, A.2
Heide, J.3
Dams, M.4
Rupp, A.K.5
Macas, J.6
-
19
-
-
84930225521
-
Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
-
Zomer A, Maynard C, Verweij FJ, Kamermans A, Schafer R, Beerling E, et al. In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell 2015;161:1046-57.
-
(2015)
Cell
, vol.161
, pp. 1046-1057
-
-
Zomer, A.1
Maynard, C.2
Verweij, F.J.3
Kamermans, A.4
Schafer, R.5
Beerling, E.6
-
20
-
-
84929353279
-
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
-
Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, et al. Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nat Commun 2015;6:7029.
-
(2015)
Nat Commun
, vol.6
, pp. 7029
-
-
Lai, C.P.1
Kim, E.Y.2
Badr, C.E.3
Weissleder, R.4
Mempel, T.R.5
Tannous, B.A.6
-
21
-
-
84929324680
-
Directional cell movement through tissues is controlled by exosome secretion
-
Sung BH, Ketova T, Hoshino D, Zijlstra A, Weaver AM. Directional cell movement through tissues is controlled by exosome secretion. Nat Commun 2015;6:7164.
-
(2015)
Nat Commun
, vol.6
, pp. 7164
-
-
Sung, B.H.1
Ketova, T.2
Hoshino, D.3
Zijlstra, A.4
Weaver, A.M.5
-
22
-
-
0018141482
-
Tumor heterogeneity and the biology of cancer invasion and metastasis
-
Fidler IJ. Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 1978;38:2651-60.
-
(1978)
Cancer Res
, vol.38
, pp. 2651-2660
-
-
Fidler, I.J.1
-
23
-
-
43049139913
-
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
-
Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, et al. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol 2008;10:619-24.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 619-624
-
-
Al-Nedawi, K.1
Meehan, B.2
Micallef, J.3
Lhotak, V.4
May, L.5
Guha, A.6
-
24
-
-
79955652381
-
Amphiregulin exosomes increase cancer cell invasion
-
Higginbotham JN, Demory Beckler M, Gephart JD, Franklin JL, Bogatcheva G, Kremers GJ, et al. Amphiregulin exosomes increase cancer cell invasion. Curr Biol 2011;21:779-86.
-
(2011)
Curr Biol
, vol.21
, pp. 779-786
-
-
Higginbotham, J.N.1
Demory Beckler, M.2
Gephart, J.D.3
Franklin, J.L.4
Bogatcheva, G.5
Kremers, G.J.6
-
25
-
-
84911966357
-
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
-
Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell 2014;26:707-21.
-
(2014)
Cancer Cell
, vol.26
, pp. 707-721
-
-
Melo, S.A.1
Sugimoto, H.2
O'Connell, J.T.3
Kato, N.4
Villanueva, A.5
Vidal, A.6
-
26
-
-
57049103401
-
Glioblastoma microvesicles transport RNA andproteinsthat promote tumour growth and provide diagnostic biomarkers
-
Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA andproteinsthat promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008;10:1470-6.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
Van Rijn, S.3
Meijer, D.H.4
Gainche, L.5
Sena-Esteves, M.6
-
27
-
-
62649095692
-
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
-
Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J. Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci U S A 2009;106:3794-9.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3794-3799
-
-
Al-Nedawi, K.1
Meehan, B.2
Kerbel, R.S.3
Allison, A.C.4
Rak, J.5
-
28
-
-
84896818399
-
Regulation of immune responses by extracellular vesicles
-
Robbins PD, Morelli AE. Regulation of immune responses by extracellular vesicles. Nat Rev Immunol 2014;14:195-208.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 195-208
-
-
Robbins, P.D.1
Morelli, A.E.2
-
29
-
-
84862620981
-
Activated T cell exosomes promote tumor invasion via Fas signaling pathway
-
Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang Q, et al. Activated T cell exosomes promote tumor invasion via Fas signaling pathway. J Immunol 2012;188: 5954-61.
-
(2012)
J Immunol
, vol.188
, pp. 5954-5961
-
-
Cai, Z.1
Yang, F.2
Yu, L.3
Yu, Z.4
Jiang, L.5
Wang, Q.6
-
30
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 2012;151:1542-56.
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
Zhang, L.2
Viloria-Petit, A.M.3
Ogunjimi, A.A.4
Inanlou, M.R.5
Chiu, E.6
-
31
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 2012;18:883-91.
-
(2012)
Nat Med
, vol.18
, pp. 883-891
-
-
Peinado, H.1
Aleckovic, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
Moreno-Bueno, G.6
-
32
-
-
84930170395
-
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
-
Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nat Cell Biol 2015;17:816-26.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 816-826
-
-
Costa-Silva, B.1
Aiello, N.M.2
Ocean, A.J.3
Singh, S.4
Zhang, H.5
Thakur, B.K.6
-
33
-
-
84904630086
-
Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-kappaB
-
Chow A,Zhou W,Liu L, FongMY, Champer J,Van Haute D, etal. Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-kappaB. Sci Rep 2014;4:5750.
-
(2014)
Sci Rep
, vol.4
, pp. 5750
-
-
Chow, A.1
Zhou, W.2
Liu, L.3
Fong, M.Y.4
Champer, J.5
Van Haute, D.6
-
34
-
-
84923194150
-
Breastcancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
-
Fong MY, Zhou W, Liu L, Alontaga AY, Chandra M, Ashby J, et al. Breastcancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol 2015;17:183-94.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 183-194
-
-
Fong, M.Y.1
Zhou, W.2
Liu, L.3
Alontaga, A.Y.4
Chandra, M.5
Ashby, J.6
-
35
-
-
84898476721
-
Cancersecreted miR-105 destroys vascular endothelial barriers to promote metastasis
-
Zhou W, Fong MY, Min Y, Somlo G, Liu L, Palomares MR, et al. Cancersecreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 2014;25:501-15.
-
(2014)
Cancer Cell
, vol.25
, pp. 501-515
-
-
Zhou, W.1
Fong, M.Y.2
Min, Y.3
Somlo, G.4
Liu, L.5
Palomares, M.R.6
-
36
-
-
84926298898
-
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier
-
Tominaga N, Kosaka N, Ono M, Katsuda T, Yoshioka Y, Tamura K, et al. Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat Commun 2015;6:6716.
-
(2015)
Nat Commun
, vol.6
, pp. 6716
-
-
Tominaga, N.1
Kosaka, N.2
Ono, M.3
Katsuda, T.4
Yoshioka, Y.5
Tamura, K.6
-
37
-
-
54949117615
-
The effects of surgery on tumor growth: A century of investigations
-
Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID. The effects of surgery on tumor growth: a century of investigations. Ann Oncol 2008;19: 1821-8.
-
(2008)
Ann Oncol
, vol.19
, pp. 1821-1828
-
-
Demicheli, R.1
Retsky, M.W.2
Hrushesky, W.J.3
Baum, M.4
Gukas, I.D.5
-
38
-
-
0002215449
-
Inhibitory effect of a primary tumor on metastasis
-
Day SB, Myers WPL, Stansly P New York, NY: Raven Press
-
Sugarbaker EV, Thornthwaite J, Ketcham AS. Inhibitory effect of a primary tumor on metastasis. In: Day SB, Myers WPL, Stansly P, editors. Progress in cancer research and therapy . New York, NY: Raven Press; 1977. 227-40.
-
(1977)
Progress in Cancer Research and Therapy
, pp. 227-240
-
-
Sugarbaker, E.V.1
Thornthwaite, J.2
Ketcham, A.S.3
-
39
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
40
-
-
0024556568
-
Presence of a growthstimulating factor in serum following primary tumor removal in mice
-
Fisher B, Gunduz N, Coyle J, Rudock C, Saffer E. Presence of a growthstimulating factor in serum following primary tumor removal in mice. Cancer Res 1989;49:1996-2001.
-
(1989)
Cancer Res
, vol.49
, pp. 1996-2001
-
-
Fisher, B.1
Gunduz, N.2
Coyle, J.3
Rudock, C.4
Saffer, E.5
-
41
-
-
84915755909
-
miR-200-containing extracellular vesicles promote breast cancer cell metastasis
-
Le MT, Hamar P, Guo C, Basar E, Perdigao-Henriques R, Balaj L, et al. miR-200-containing extracellular vesicles promote breast cancer cell metastasis. J Clin Invest 2014;124:5109-28.
-
(2014)
J Clin Invest
, vol.124
, pp. 5109-5128
-
-
Le, M.T.1
Hamar, P.2
Guo, C.3
Basar, E.4
Perdigao-Henriques, R.5
Balaj, L.6
-
42
-
-
84895552868
-
Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin
-
Federici C, Petrucci F, Caimi S, Cesolini A, Logozzi M, Borghi M, et al. Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin. PLoS ONE 2014;9:e88193.
-
(2014)
PLoS ONE
, vol.9
, pp. e88193
-
-
Federici, C.1
Petrucci, F.2
Caimi, S.3
Cesolini, A.4
Logozzi, M.5
Borghi, M.6
-
43
-
-
84928588794
-
Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein
-
Lv MM, Zhu XY, Chen WX, Zhong SL, Hu Q, Ma TF, et al. Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein. Tumour Biol 2014;35:10773-9.
-
(2014)
Tumour Biol
, vol.35
, pp. 10773-10779
-
-
Lv, M.M.1
Zhu, X.Y.2
Chen, W.X.3
Zhong, S.L.4
Hu, Q.5
Ma, T.F.6
-
44
-
-
84899626532
-
Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance
-
Ma X, Chen Z, Hua D, He D, Wang L, Zhang P, et al. Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance. Proc Natl Acad Sci U S A 2014;111:6389-94.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 6389-6394
-
-
Ma, X.1
Chen, Z.2
Hua, D.3
He, D.4
Wang, L.5
Zhang, P.6
-
45
-
-
84905705777
-
Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment
-
Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, et al. Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics 2014;14:1845-56.
-
(2014)
Proteomics
, vol.14
, pp. 1845-1856
-
-
Choi, D.Y.1
You, S.2
Jung, J.H.3
Lee, J.C.4
Rho, J.K.5
Lee, K.Y.6
-
46
-
-
84908275360
-
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
-
Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 2014;159:499-513.
-
(2014)
Cell
, vol.159
, pp. 499-513
-
-
Boelens, M.C.1
Wu, T.J.2
Nabet, B.Y.3
Xu, B.4
Qiu, Y.5
Yoon, T.6
-
47
-
-
0035933154
-
Horizontal transfer of oncogenes by uptake of apoptotic bodies
-
Bergsmedh A, Szeles A, Henriksson M, Bratt A, Folkman MJ, Spetz AL, et al. Horizontal transfer of oncogenes by uptake of apoptotic bodies. Proc Natl Acad Sci U S A 2001;98:6407-11.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6407-6411
-
-
Bergsmedh, A.1
Szeles, A.2
Henriksson, M.3
Bratt, A.4
Folkman, M.J.5
Spetz, A.L.6
-
48
-
-
67349258571
-
Horizontal transfer of tumor DNA to endothelial cells in vivo
-
Ehnfors J, Kost-Alimova M, Persson NL, Bergsmedh A, Castro J, Levchenko-Tegnebratt T, et al. Horizontal transfer of tumor DNA to endothelial cells in vivo. Cell Death Differ 2009;16:749-57.
-
(2009)
Cell Death Differ
, vol.16
, pp. 749-757
-
-
Ehnfors, J.1
Kost-Alimova, M.2
Persson, N.L.3
Bergsmedh, A.4
Castro, J.5
Levchenko-Tegnebratt, T.6
|