메뉴 건너뛰기




Volumn 41, Issue 3, 2016, Pages E46-E55

Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; NEUROLEPTIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TOLL LIKE RECEPTOR 4; MYD88 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

EID: 84964761434     PISSN: 11804882     EISSN: 14882434     Source Type: Journal    
DOI: 10.1503/jpn.150195     Document Type: Article
Times cited : (69)

References (63)
  • 2
    • 84923302342 scopus 로고    scopus 로고
    • Inflammation and immunity in schizophrenia: Implications for pathophysiology and treatment
    • Khandaker GM, Cousins L, Deakin J, et al. Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment. Lancet Psychiatry 2015;2:258-70.
    • (2015) Lancet Psychiatry , vol.2 , pp. 258-270
    • Khandaker, G.M.1    Cousins, L.2    Deakin, J.3
  • 3
    • 84876784407 scopus 로고    scopus 로고
    • Innate immunity in the CNS: Redefining the relationship between the CNS and Its environment
    • Lampron A, Elali A, Rivest S. Innate immunity in the CNS: redefining the relationship between the CNS and Its environment. Neuron 2013;78:214-32.
    • (2013) Neuron , vol.78 , pp. 214-232
    • Lampron, A.1    Elali, A.2    Rivest, S.3
  • 4
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1:135-45.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 5
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 6
    • 80052315340 scopus 로고    scopus 로고
    • Toll-like receptors in health and disease in the brain: Mechanisms and therapeutic potential
    • Hanke ML, Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin Sci (Lond) 2011;121:367-87.
    • (2011) Clin Sci (Lond) , vol.121 , pp. 367-387
    • Hanke, M.L.1    Kielian, T.2
  • 7
    • 77955383770 scopus 로고    scopus 로고
    • DAMPening inflammation by modulating TLR signalling
    • Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010;pii:672395.
    • (2010) Mediators Inflamm
    • Piccinini, A.M.1    Midwood, K.S.2
  • 8
    • 0035104961 scopus 로고    scopus 로고
    • Toll-like receptors: Their physiological role and signal transduction system
    • Takeuchi O, Akira S. Toll-like receptors: their physiological role and signal transduction system. Int Immunopharmacol 2001;1:625-35.
    • (2001) Int Immunopharmacol , vol.1 , pp. 625-635
    • Takeuchi, O.1    Akira, S.2
  • 9
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • Shimazu R, Akashi S, Ogata H, et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999;189:1777-82.
    • (1999) J Exp Med , vol.189 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3
  • 11
    • 45849103124 scopus 로고    scopus 로고
    • Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms
    • García-Bueno B, Caso JR, Leza JC. Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neurosci Biobehav Rev 2008;32:1136-51.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 1136-1151
    • García-Bueno, B.1    Caso, J.R.2    Leza, J.C.3
  • 12
    • 84870668351 scopus 로고    scopus 로고
    • Stress-induced neuroinflammation: Role of the Toll-like receptor-4 pathway
    • Gárate I, Garcia-Bueno B, Madrigal JL, et al. Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway. Biol Psychiatry 2013;73:32-43.
    • (2013) Biol Psychiatry , vol.73 , pp. 32-43
    • Gárate, I.1    Garcia-Bueno, B.2    Madrigal, J.L.3
  • 13
    • 84895756733 scopus 로고    scopus 로고
    • Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: Toward an integrative inflammatory hypothesis of schizophrenia
    • García-Bueno B, Bioque M, Mac-Dowell KS, et al. Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. Schizophr Bull 2014a;40:376-87.
    • (2014) Schizophr Bull , vol.40 , pp. 376-387
    • García-Bueno, B.1    Bioque, M.2    Mac-Dowell, K.S.3
  • 14
    • 84935829325 scopus 로고    scopus 로고
    • Pro-/antiinflammatory dysregulation in early psychosis: Results from a 1-year follow-up study
    • García-Bueno B, Bioque M, MacDowell KS, et al. Pro-/antiinflammatory dysregulation in early psychosis: results from a 1-year follow-up study. Int J Neuropsychopharmacol 2014;18:pii: pyu037.
    • (2014) Int J Neuropsychopharmacol , vol.18
    • García-Bueno, B.1    Bioque, M.2    MacDowell, K.S.3
  • 15
    • 79955469799 scopus 로고    scopus 로고
    • The antiinflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia
    • Martínez-Gras I, Pérez-Nievas BG, García-Bueno B, et al. The antiinflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. Schizophr Res 2011;128:15-22.
    • (2011) Schizophr Res , vol.128 , pp. 15-22
    • Martínez-Gras, I.1    Pérez-Nievas, B.G.2    García-Bueno, B.3
  • 16
    • 80052334860 scopus 로고    scopus 로고
    • Enhanced peripheral toll-like receptor responses in psychosis: Further evidence of a pro-inflammatory phenotype
    • McKernan DP, Dennison U, Gaszner G et al. Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype. Transl Psychiatry 2011;1:e36.
    • (2011) Transl Psychiatry , vol.1
    • McKernan, D.P.1    Dennison, U.2    Gaszner, G.3
  • 17
    • 84868661601 scopus 로고    scopus 로고
    • Impaired monocyte activation in schizophrenia
    • Müller N, Wagner JK, Krause D, et al. Impaired monocyte activation in schizophrenia. Psychiatry Res 2012;198:341-6.
    • (2012) Psychiatry Res , vol.198 , pp. 341-346
    • Müller, N.1    Wagner, J.K.2    Krause, D.3
  • 18
    • 84892647238 scopus 로고    scopus 로고
    • Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: An update
    • Sommer IE, van Westrhenen R, Begemann MJ, et al. Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update. Schizophr Bull 2014;40:181-91.
    • (2014) Schizophr Bull , vol.40 , pp. 181-191
    • Sommer, I.E.1    van Westrhenen, R.2    Begemann, M.J.3
  • 19
    • 84924975884 scopus 로고    scopus 로고
    • Infection and inflammation in schizophrenia and bipolar disorder: A genome wide study for interactions with genetic variation
    • Avramopoulos D, Pearce BD, McGrath J, et al. Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation. PLoS One 2015;10:e0116696.
    • (2015) PLoS One , vol.10
    • Avramopoulos, D.1    Pearce, B.D.2    McGrath, J.3
  • 20
    • 77956192274 scopus 로고    scopus 로고
    • Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data
    • Jia P, Wang L, Meltzer HY, et al. Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophr Res 2010;122:38-42.
    • (2010) Schizophr Res , vol.122 , pp. 38-42
    • Jia, P.1    Wang, L.2    Meltzer, H.Y.3
  • 21
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009;460:748-52.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3
  • 22
    • 84878220679 scopus 로고    scopus 로고
    • Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
    • Hamshere ML, Walters JT, Smith R, et al. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry 2013;18:708-12.
    • (2013) Mol Psychiatry , vol.18 , pp. 708-712
    • Hamshere, M.L.1    Walters, J.T.2    Smith, R.3
  • 23
    • 84889086473 scopus 로고    scopus 로고
    • Polymorphism of Toll-like receptor 4 gene in bipolar disorder
    • Oliveira J, Busson M, Etain B, et al. Polymorphism of Toll-like receptor 4 gene in bipolar disorder. J Affect Disord 2014;152-154:395-402.
    • (2014) J Affect Disord , vol.152-154 , pp. 395-402
    • Oliveira, J.1    Busson, M.2    Etain, B.3
  • 24
    • 79955745301 scopus 로고    scopus 로고
    • Toll-like receptor signaling in neural plasticity and disease
    • Okun E, Griffioen KJ, Mattson MP. Toll-like receptor signaling in neural plasticity and disease. Trends Neurosci 2011;34:269-81.
    • (2011) Trends Neurosci , vol.34 , pp. 269-281
    • Okun, E.1    Griffioen, K.J.2    Mattson, M.P.3
  • 25
    • 84877325936 scopus 로고    scopus 로고
    • The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) hypothesis: A novel postulate to understand schizophrenia
    • Venkatasubramanian G, Debnath M. The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) hypothesis: a novel postulate to understand schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2013;44:301-11.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.44 , pp. 301-311
    • Venkatasubramanian, G.1    Debnath, M.2
  • 26
    • 84881023923 scopus 로고    scopus 로고
    • Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia
    • Severance EG, Gressitt KL, Stallings CR, et al. Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia. Schizophr Res 2013;148:130-7.
    • (2013) Schizophr Res , vol.148 , pp. 130-137
    • Severance, E.G.1    Gressitt, K.L.2    Stallings, C.R.3
  • 27
    • 85005808068 scopus 로고    scopus 로고
    • Paliperidone prevents brain Toll-like receptor 4 pathway activation and neuroinflammation in rat models of acute and chronic restraint stress
    • MacDowell KS, Caso J, Martin-Hernandez D, et al. Paliperidone prevents brain Toll-like receptor 4 pathway activation and neuroinflammation in rat models of acute and chronic restraint stress. Int J Neuropsychopharmacol 2014;18:pii:pyu070.
    • (2014) Int J Neuropsychopharmacol , vol.18
    • MacDowell, K.S.1    Caso, J.2    Martin-Hernandez, D.3
  • 28
    • 0029126129 scopus 로고
    • Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I. Remapping of areas 9 and 46 using quantitative criteria
    • Rajkowska G, Goldman-Rakic PS. Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I. Remapping of areas 9 and 46 using quantitative criteria. Cereb Cortex 1995;5:307-22.
    • (1995) Cereb Cortex , vol.5 , pp. 307-322
    • Rajkowska, G.1    Goldman-Rakic, P.S.2
  • 29
    • 77956177387 scopus 로고    scopus 로고
    • Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: Antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients
    • García-Sevilla JA, Alvaro-Bartolome M, Diez-Alarcia R, et al. Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients. Eur Neuropsychopharmacol 2010;20:721-30.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 721-730
    • García-Sevilla, J.A.1    Alvaro-Bartolome, M.2    Diez-Alarcia, R.3
  • 30
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Müller MM, et al. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989;17:6419.
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Müller, M.M.3
  • 31
    • 0023183219 scopus 로고
    • Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria
    • Das NP, Ratty AK. Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria. Biochem Med Metab Biol 1987;37:258-64.
    • (1987) Biochem Med Metab Biol , vol.37 , pp. 258-264
    • Das, N.P.1    Ratty, A.K.2
  • 32
    • 0027969436 scopus 로고
    • DSM-IV in progress. Changes in substance-related, schizophrenic, and other primarily adult disorders
    • First MB, Frances AJ, Pincus HA, et al. DSM-IV in progress. Changes in substance-related, schizophrenic, and other primarily adult disorders. Hosp Community Psychiatry 1994;45:18-20.
    • (1994) Hosp Community Psychiatry , vol.45 , pp. 18-20
    • First, M.B.1    Frances, A.J.2    Pincus, H.A.3
  • 33
    • 49049086157 scopus 로고    scopus 로고
    • 141C Ins/ Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population
    • Lafuente A, Bernardo M, Mas S, et al. 141C Ins/Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population. Psychiatr Genet 2008;18:122-7.
    • (2008) Psychiatr Genet , vol.18 , pp. 122-127
    • Lafuente, A.1    Bernardo, M.2    Mas, S.3
  • 34
    • 34047179603 scopus 로고    scopus 로고
    • SNPassoc: An R package to perform whole genome association studies
    • González JR, Armengol L, Sole X, et al. SNPassoc: an R package to perform whole genome association studies. Bioinformatics 2007; 23:644-5.
    • (2007) Bioinformatics , vol.23 , pp. 644-645
    • González, J.R.1    Armengol, L.2    Sole, X.3
  • 35
    • 33745599582 scopus 로고    scopus 로고
    • A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility
    • Moore JH, Gilbert JC, Tsai CT, et al. A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. J Theor Biol 2006;241:252-61.
    • (2006) J Theor Biol , vol.241 , pp. 252-261
    • Moore, J.H.1    Gilbert, J.C.2    Tsai, C.T.3
  • 36
    • 84862170482 scopus 로고    scopus 로고
    • Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking
    • Young AM, Vetreno RP, Qin L, et al. Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking. Front Psychiatry 2011;2:27.
    • (2011) Front Psychiatry , vol.2 , pp. 27
    • Young, A.M.1    Vetreno, R.P.2    Qin, L.3
  • 37
    • 84877123887 scopus 로고    scopus 로고
    • Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients
    • Rao JS, Kim HW, Harry GJ, et al. Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients. Schizophr Res 2013;147:24-31.
    • (2013) Schizophr Res , vol.147 , pp. 24-31
    • Rao, J.S.1    Kim, H.W.2    Harry, G.J.3
  • 38
    • 85000416237 scopus 로고    scopus 로고
    • Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes
    • Malki K, Pain O, Tosto MG, et al. Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes. Transl Psychiatry 2015;5:e519.
    • (2015) Transl Psychiatry , vol.5
    • Malki, K.1    Pain, O.2    Tosto, M.G.3
  • 39
    • 84862170482 scopus 로고    scopus 로고
    • Aberrant NF-kappaB expression in autism spectrum condition: A mechanism for neuroinflammation
    • Young AM, Campbell E, Lynch S, et al. Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation. Front Psychiatry 2011;2:27.
    • (2011) Front Psychiatry , vol.2 , pp. 27
    • Young, A.M.1    Campbell, E.2    Lynch, S.3
  • 40
    • 84884556157 scopus 로고    scopus 로고
    • Meta-analysis of gene coexpression networks in the post-mortem prefrontal cortex of patients with schizophrenia and unaffected controls
    • Mistry M, Gillis J, Pavlidis P. Meta-analysis of gene coexpression networks in the post-mortem prefrontal cortex of patients with schizophrenia and unaffected controls. BMC Neurosci 2013;14:105.
    • (2013) BMC Neurosci , vol.14 , pp. 105
    • Mistry, M.1    Gillis, J.2    Pavlidis, P.3
  • 41
    • 65549097353 scopus 로고    scopus 로고
    • The impact of heat shock protein 70 gene variations on clinical presentation and outcome in schizophrenic inpatients
    • Pae CU, Drago A, Kim JJ, et al. The impact of heat shock protein 70 gene variations on clinical presentation and outcome in schizophrenic inpatients. Neuropsychobiology 2009;59:135-41.
    • (2009) Neuropsychobiology , vol.59 , pp. 135-141
    • Pae, C.U.1    Drago, A.2    Kim, J.J.3
  • 43
    • 84925452526 scopus 로고    scopus 로고
    • The poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery
    • Reisinger S, Khan D, Kong E, et al. The poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery. Pharmacol Ther 2015;149:213-26.
    • (2015) Pharmacol Ther , vol.149 , pp. 213-226
    • Reisinger, S.1    Khan, D.2    Kong, E.3
  • 44
    • 4644340557 scopus 로고    scopus 로고
    • Divergent trophoblast responses to bacterial products mediated by TLRs
    • Abrahams VM, Bole-Aldo P, Kim YM, et al. Divergent trophoblast responses to bacterial products mediated by TLRs. J Immunol 2004;173:4286-96.
    • (2004) J Immunol , vol.173 , pp. 4286-4296
    • Abrahams, V.M.1    Bole-Aldo, P.2    Kim, Y.M.3
  • 45
    • 79551520132 scopus 로고    scopus 로고
    • Induction of Toll-like receptor 3-mediated immunity during gestation inhibits cortical neurogenesis and causes behavioral disturbances
    • De MJ, Yaddanapudi K, Hornig M, et al. Induction of Toll-like receptor 3-mediated immunity during gestation inhibits cortical neurogenesis and causes behavioral disturbances. MBio 2010;1:pii: e00176-10.
    • (2010) MBio , vol.1
    • De, M.J.1    Yaddanapudi, K.2    Hornig, M.3
  • 46
    • 84884354746 scopus 로고    scopus 로고
    • So depression is an inflammatory disease, but where does the inflammation come from?
    • Berk M, Williams LJ, Jacka FN, et al. So depression is an inflammatory disease, but where does the inflammation come from? BMC Med 2013;11:200.
    • (2013) BMC Med , vol.11 , pp. 200
    • Berk, M.1    Williams, L.J.2    Jacka, F.N.3
  • 47
    • 84907756116 scopus 로고    scopus 로고
    • The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration
    • Rosenberger K, Derkow K, Dembny P, et al. The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration. J Neuroinflammation 2014;11:166.
    • (2014) J Neuroinflammation , vol.11 , pp. 166
    • Rosenberger, K.1    Derkow, K.2    Dembny, P.3
  • 48
    • 80052853015 scopus 로고    scopus 로고
    • Meta-analysis of cytokine alterations in schizophrenia: Clinical status and antipsychotic effects
    • Miller BJ, Buckley P, Seabolt W, et al. Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects. Biol Psychiatry 2011;70:663-71.
    • (2011) Biol Psychiatry , vol.70 , pp. 663-671
    • Miller, B.J.1    Buckley, P.2    Seabolt, W.3
  • 49
    • 84871518090 scopus 로고    scopus 로고
    • Risperidone normalizes increased inflammatory parameters and restores antiinflammatory pathways in a model of neuroinflammation
    • MacDowell KS, Garcia-Bueno B, Madrigal JL, et al. Risperidone normalizes increased inflammatory parameters and restores antiinflammatory pathways in a model of neuroinflammation. Int J Neuropsychopharmacol 2013;16:121-35.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 121-135
    • MacDowell, K.S.1    Garcia-Bueno, B.2    Madrigal, J.L.3
  • 50
    • 84922635801 scopus 로고    scopus 로고
    • Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier
    • Elmorsy E, Elzalabany LM, Elsheikha HM, et al. Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier. Brain Res 2014;1583:255-68.
    • (2014) Brain Res , vol.1583 , pp. 255-268
    • Elmorsy, E.1    Elzalabany, L.M.2    Elsheikha, H.M.3
  • 51
    • 33846847640 scopus 로고    scopus 로고
    • Long-term antipsychotic treatments and crossover studies in rats: Differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain
    • Pillai A, Parikh V, Terry AV Jr, et al. Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J Psychiatr Res 2007;41:372-86.
    • (2007) J Psychiatr Res , vol.41 , pp. 372-386
    • Pillai, A.1    Parikh, V.2    Terry, A.V.3
  • 52
    • 79960778969 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the 3'-untranslated region of MyD88 gene is associated with Buerger disease but not with Takayasu arteritis in Japanese
    • Chen Z, Nakajima T, Inoue Y, et al. A single nucleotide polymorphism in the 3'-untranslated region of MyD88 gene is associated with Buerger disease but not with Takayasu arteritis in Japanese. J Hum Genet 2011;56:545-7.
    • (2011) J Hum Genet , vol.56 , pp. 545-547
    • Chen, Z.1    Nakajima, T.2    Inoue, Y.3
  • 53
    • 84893851711 scopus 로고    scopus 로고
    • The *1244 A>G polymorphism of MyD88 (rs7744) is closely associated with susceptibility to ulcerative colitis
    • Matsunaga K, Tahara T, Shiroeda H, et al. The *1244 A>G polymorphism of MyD88 (rs7744) is closely associated with susceptibility to ulcerative colitis. Mol Med Rep 2014;9:28-32.
    • (2014) Mol Med Rep , vol.9 , pp. 28-32
    • Matsunaga, K.1    Tahara, T.2    Shiroeda, H.3
  • 54
    • 77955022748 scopus 로고    scopus 로고
    • Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways
    • Potter C, Cordell HJ, Barton A, et al. Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways. Ann Rheum Dis 2010;69:1315-20.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1315-1320
    • Potter, C.1    Cordell, H.J.2    Barton, A.3
  • 55
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/ Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns K, Janssens S, Brissoni B, et al. Inhibition of interleukin 1 receptor/ Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med 2003;197:263-8.
    • (2003) J Exp Med , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3
  • 56
    • 0038003196 scopus 로고    scopus 로고
    • Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia
    • Lewis CM, Levinson DF, Wise LH, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia. Am J Hum Genet 2003;73:34-48.
    • (2003) Am J Hum Genet , vol.73 , pp. 34-48
    • Lewis, C.M.1    Levinson, D.F.2    Wise, L.H.3
  • 57
    • 84893379680 scopus 로고    scopus 로고
    • ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population
    • He K, Wang Q, Chen J, et al. ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population. Prog Neuropsychopharmacol Biol Psychiatry 2014;51:34-8.
    • (2014) Prog Neuropsychopharmacol Biol Psychiatry , vol.51 , pp. 34-38
    • He, K.1    Wang, Q.2    Chen, J.3
  • 58
    • 84885020424 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 13 new risk loci for schizophrenia
    • Ripke S, O'Dushlaine C, Chambert K, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 2013;45:1150-9.
    • (2013) Nat Genet , vol.45 , pp. 1150-1159
    • Ripke, S.1    O'Dushlaine, C.2    Chambert, K.3
  • 59
    • 33846439768 scopus 로고    scopus 로고
    • Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: A potential clinical marker and mediator of severe sepsis
    • Opal SM, Lim YP, Siryaporn E, et al. Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis. Crit Care Med 2007; 35:387-92.
    • (2007) Crit Care Med , vol.35 , pp. 387-392
    • Opal, S.M.1    Lim, Y.P.2    Siryaporn, E.3
  • 60
    • 77955176723 scopus 로고    scopus 로고
    • Functional polymorphism in the interleukin-6 and interleukin-10 genes in patients with paranoid schizophrenia-a case-control study
    • Paul-Samojedny M, Kowalczyk M, Suchanek R, et al. Functional polymorphism in the interleukin-6 and interleukin-10 genes in patients with paranoid schizophrenia-a case-control study. J Mol Neurosci 2010;42:112-9.
    • (2010) J Mol Neurosci , vol.42 , pp. 112-119
    • Paul-Samojedny, M.1    Kowalczyk, M.2    Suchanek, R.3
  • 61
    • 77954144181 scopus 로고    scopus 로고
    • Convergent evidence shows a positive association of interleukin-1 gene complex locus with susceptibility to schizophrenia in the Caucasian population
    • Xu M, He L. Convergent evidence shows a positive association of interleukin-1 gene complex locus with susceptibility to schizophrenia in the Caucasian population. Schizophr Res 2010;120:131-42.
    • (2010) Schizophr Res , vol.120 , pp. 131-142
    • Xu, M.1    He, L.2
  • 62
    • 84864334611 scopus 로고    scopus 로고
    • Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia
    • Zakharyan R, Petrek M, Arakelyan A, et al. Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia. Tissue Antigens 2012;80:136-42.
    • (2012) Tissue Antigens , vol.80 , pp. 136-142
    • Zakharyan, R.1    Petrek, M.2    Arakelyan, A.3
  • 63
    • 84900386452 scopus 로고    scopus 로고
    • Relationship between interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naive schizophrenia: Evidence for differential susceptibility?
    • Kalmady SV, Venkatasubramanian G, Shivakumar V, et al. Relationship between interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naive schizophrenia: Evidence for differential susceptibility? PLoS One 2014;9:e96021.
    • (2014) PLoS One , vol.9
    • Kalmady, S.V.1    Venkatasubramanian, G.2    Shivakumar, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.