Effects of dabigatran on the cellular and protein phase of coagulation in patients with coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel: Results from a prospective, randomised, double-blind, placebo-controlled study

Thrombosis and Haemostasis

Volumn 115, Issue 3, 2016, Pages 622-631

  Franchi, Francesco ^a   Rollini, Fabiana ^a   Cho, Jung Rae ^a   King, Rhodri ^b   Phoenix, Fladia ^b   Bhatti, Mona ^a   DeGroat, Christopher ^a   Tello Montoliu, Antonio ^a   Zenni, Martin M ^a   Guzman, Luis A ^a   Bass, Theodore A ^a   Ajjan, Ramzi A ^b   Angiolillo, Dominick J ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Antithrombin; Pharmacodynamics; Platelet pharmacology; Thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; DABIGATRAN; PLACEBO; PROSTAGLANDIN E1; THROMBIN RECEPTOR ACTIVATING PEPTIDE; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CYTOCHROME P450; TICLOPIDINE; VITAMIN K GROUP;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLEEDING; BLOOD CLOTTING; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; FIBRINOLYSIS; HEMODYNAMICS; HUMAN; KINETICS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PHARMACODYNAMIC PARAMETERS; PRIORITY JOURNAL; REVASCULARIZATION; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOELASTOGRAPHY; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BLOOD; BLOOD CLOTTING PARAMETERS; CHEMISTRY; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; ELECTRODE; LIGHT; METABOLISM; ORAL DRUG ADMINISTRATION; PHOTOMETRY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE; THROMBOSIS;

ADMINISTRATION, ORAL; AGED; ANTICOAGULANTS; ASPIRIN; BLOOD COAGULATION; BLOOD PLATELETS; CORONARY ARTERY DISEASE; CYTOCHROME P-450 ENZYME SYSTEM; DABIGATRAN; DOUBLE-BLIND METHOD; ELECTRODES; FEMALE; HUMANS; LIGHT; MALE; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; PROSPECTIVE STUDIES; THROMBELASTOGRAPHY; THROMBOSIS; TICLOPIDINE; VITAMIN K;

EID: 84964699823     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH15-06-0467     Document Type: Article

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