Violence-related PTSD and neural activation when seeing emotionally charged male-female interactions

Social Cognitive and Affective Neuroscience

Volumn 10, Issue 5, 2015, Pages 645-653

  Moser, Dominik A ^a,b   Aue, Tatjana ^a   Suardi, Francesca ^a,b   Kutlikova, Hana ^b   Cordero, Maria I ^b,c   Rossignol, Ana Sancho ^b   Favez, Nicolas ^a   Serpa, Sandra Rusconi ^a,b   Schechter, Daniel S ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Emotion regulation; fMRI; Human interaction; Interpersonal violence; Parental PTSD

Indexed keywords

ADULT; DOMESTIC VIOLENCE; EMOTION; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN RELATION; MALE; MOTHER; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; POSTTRAUMATIC STRESS DISORDER; PREFRONTAL CORTEX; PSYCHOLOGY; VIOLENCE; YOUNG ADULT;

ADULT; DOMESTIC VIOLENCE; EMOTIONS; FEMALE; HIPPOCAMPUS; HUMANS; INTERPERSONAL RELATIONS; MAGNETIC RESONANCE IMAGING; MALE; MOTHERS; PHOTIC STIMULATION; PREFRONTAL CORTEX; STRESS DISORDERS, POST-TRAUMATIC; VIOLENCE; YOUNG ADULT;

EID: 84964698951     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nsu099     Document Type: Article

References (60)

1. American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: American Psychiatric Publishing.
2. American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders. Arlington, VA: American Psychiatric Publishing.
3. Blake, D.D., Weathers, F.W., Nagy, L.M., Kaloupek, D.G., Gusman, F.D., Charney, D.S., Keane, T.M. (1995). The development of a Clinician-Administered PTSD Scale. Journal of Traumatic Stress, 8(1), 75-90.
4. Bluhm, R.L., Frewen, P.A., Coupland, N.C., Densmore, M., Schore, A.N., Lanius, R.A. (2012). Neural correlates of self-reflection in post-traumatic stress disorder. Acta Psychiatrica Scandinavica, 125(3), 238-46.
5. Britton, J.C., Phan, K.L., Taylor, S.F., Fig, L.M., Liberzon, I. (2005). Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery. Biological Psychiatry, 57(8), 832-40.
6. Brohawn, K.H., Offringa, R., Pfaff, D.L., Hughes, K.C., Shin, L.M. (2010). The neural correlates of emotional memory in posttraumatic stress disorder. Biological Psychiatry, 68(11), 1023-30.
7. Bryant, R.A., Kemp, A.H., Felmingham, K.L., Liddell, B., Olivieri, G., Peduto, A., Gordon, E., Williams, L.M. (2008). Enhanced amygdala and medial prefrontal activation during nonconscious processing of fear in posttraumatic stress disorder: an fMRI study. Human Brain Mapping, 29(5), 517-23.
8. Buckner, R.L., Andrews-Hanna, J.R., Schacter, D.L. (2008). The brain's default network: anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences, 1124, 1-38.
9. Burgdorf, J., Panksepp, J. (2006). The neurobiology of positive emotions. Neuroscience and Biobehavioral Reviews, 30(2), 173-87.
10. Cannon, E.A., Bonomi, A.E., Anderson, M.L., Rivara, F.P. (2009). The intergenerational transmission of witnessing intimate partner violence. Archives of Pediatrics and Adolescent Medicine, 163(8), 706-8.
11. Chen, A.C., Etkin, A. (2013). Hippocampal network connectivity and activation differentiates post-traumatic stress disorder from generalized anxiety disorder. Neuropsychopharmacology, 38(10), 1889-98.
12. Declercq, F., Vanheule, S., Deheegher, J. (2010). Alexithymia and posttraumatic stress: subscales and symptom clusters. Journal of Clinical Psychology, 66(10), 1076-89.
13. Dickie, E.W., Brunet, A., Akerib, V., Armony, J.L. (2008). An fMRI investigation of memory encoding in PTSD: influence of symptom severity. Neuropsychologia, 46(5), 1522-31.
14. Dickie, E.W., Brunet, A., Akerib, V., Armony, J.L. (2011). Neural correlates of recovery from post-traumatic stress disorder: a longitudinal fMRI investigation of memory encoding. Neuropsychologia, 49(7), 1771-8.
15. Etkin, A., Egner, T., Kalisch, R. (2011). Emotional processing in anterior cingulate and medial prefrontal cortex. Trends in Cognitive Sciences, 15(2), 85-93.
16. Etkin, A., Wager, T.D. (2007). Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. The American Journal of Psychiatry, 164(10), 1476-88.
17. Felmingham, K., Williams, L.M., Kemp, A.H., Liddell, B., Falconer, E., Peduto, A., Bryant, R. (2010). Neural responses to masked fear faces: sex differences and trauma exposure in posttraumatic stress disorder. Journal of Abnormal Psychology, 119(1), 241-7.
18. Felmingham, K.L., Williams, L.M., Kemp, A.H., Rennie, C., Gordon, E., Bryant, R.A. (2009). Anterior cingulate activity to salient stimuli is modulated by autonomic arousal in posttraumatic stress disorder. Psychiatry Research, 173(1), 59-62.
19. Fonzo, G.A., Flagan, T.M., Sullivan, S., Allard, C.B., Grimes, E.M., Simmons, A.N., Paulus, M.P., Stein, M.B. (2013). Neural functional and structural correlates of childhood maltreatment in women with intimate-partner violence-related posttraumatic stress disorder. Psychiatry Research, 211(2), 93-103.
20. Fonzo, G.A., Simmons, A.N., Thorp, S.R., Norman, S.B., Paulus, M.P., Stein, M.B. (2010). Exaggerated and disconnected insular-amygdalar blood oxygenation level-dependent response to threat-related emotional faces in women with intimate-partner violence posttraumatic stress disorder. Biological Psychiatry, 68(5), 433-41.
21. Frewen, P.A., Lanius, R.A., Dozois, D.J., Neufeld, R.W., Pain, C., Hopper, J.W., Densmore, M., Stevens, T.K. (2008). Clinical and neural correlates of alexithymia in posttraumatic stress disorder. Journal of Abnormal Psychology, 117(1), 171-81.
22. Hayes, J.P., Hayes, S.M., Mikedis, A.M. (2012). Quantitative meta-analysis of neural activity in posttraumatic stress disorder. Biology of Mood and Anxiety Disorders, 2(1), 9.
23. Kalisch, R. (2009). The functional neuroanatomy of reappraisal: time matters. Neuroscience and Biobehavioral Reviews, 33(8), 1215-26.
24. Kalisch, R., Wiech, K., Critchley, H.D., Dolan, R.J. (2006). Levels of appraisal: a medial prefrontal role in high-level appraisal of emotional material. Neuroimage, 30(4), 1458-66.
25. Killgore, W.D., Britton, J.C., Schwab, Z.J., Price, L.M., Weiner, M.R., Gold, A.L., Rosso, I.M., Simon, N.M., Pollack, M.H., Rauch, S.L. (2014). Cortico-limbic responses to masked affective faces across ptsd, panic disorder, and specific phobia. Depress Anxiety, 31(2), 150-9.
26. Kim, M.J., Chey, J., Chung, A., Bae, S., Khang, H., Ham, B., Yoon, S.J., Jeong, D.U., Lyoo, I.K. (2008). Diminished rostral anterior cingulate activity in response to threat-related events in posttraumatic stress disorder. Journal of Psychiatric Research, 42(4), 268-77.
27. Lanius, R.A., Williamson, P.C., Densmore, M., Boksman, K., Gupta, M.A., Neufeld, R.W., Gati, J.S., Menon, R.S. (2001). Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation. The American Journal of Psychiatry, 158(11), 1920-2.
28. Lanius, R.A., Williamson, P.C., Hopper, J., Densmore, M., Boksman, K., Gupta, M.A., Neufeld, R.W., Gati, J.S., Menon, R.S. (2003). Recall of emotional states in posttraumatic stress disorder: an fMRI investigation. Biological Psychiatry, 53(3), 204-10.
29. Largo, R.H., Pfister, D., Molinari, L., Kundu, S., Lipp, A., Duc, G. (1989). Significance of prenatal and postnatal factors in the development of AGA-preterm children at 5-7 years. Developmental Medicine and Child Neurology, 31(4), 440-56.
30. Maier, S., Szalkowski, A., Kamphausen, S., Perlov, E., Feige, B., Blechert, J., Philipsen, A., van Elst, L.T., Kalisch, R., Tuscher, O. (2012). Clarifying the role of the rostral dmPFC/ dACC in fear/anxiety: learning, appraisal or expression? PLoS One, 7(11), e50120.
31. Mazza, M., Giusti, L., Albanese, A., Mariano, M., Pino, M.C., Roncone, R. (2012). Social cognition disorders in military police officers affected by posttraumatic stress disorder after the attack of An-Nasiriyah in Iraq 2006. Psychiatry Research, 198(2), 248-52.
32. Mazza, M., Tempesta, D., Pino, M.C., Catalucci, A., Gallucci, M., Ferrara, M. (2013). Regional cerebral changes and functional connectivity during the observation of negative emotional stimuli in subjects with post-traumatic stress disorder. European Archives of Psychiatry and Clinical Neuroscience, 263(7), 575-83.
33. McIntyre, J.K., Widom, C.S. (2011). Childhood victimization and crime victimization. Journal of Interpersonal Violence, 26(4), 640-63.
34. Moser, D.A., Aue, T., Wang, Z., Rusconi Serpa, S., Favez, N., Peterson, B.S., Schechter, D.S. (2013). Limbic brain responses in mothers with post-traumatic stress disorder and comorbid dissociation to video clips of their children. Stress, 16(5), 493-502.
35. Motzkin, J.C., Philippi, C.L., Wolf, R.C., Baskaya, M.K., Koenigs, M. (2015). Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans. Biological Psychiatry, 77(3), 276-84.
36. Nietlisbach, G., Maercker, A., Rossler, W., Haker, H. (2010). Are empathic abilities impaired in posttraumatic stress disorder? Psychological Reports, 106(3), 832-44.
37. Offringa, R., Handwerger Brohawn, K., Staples, L.K., Dubois, S.J., Hughes, K.C., Pfaff, D.L., Vanelzakker, M.B., Davis, F.C., Shin, L.M. (2013). Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD. Biology of Mood and Anxiety Disorders, 3(1), 10.
38. Pico-Alfonso, M.A. (2005). Psychological intimate partner violence: the major predictor of posttraumatic stress disorder in abused women. Neuroscience and Biobehavioral Reviews, 29(1), 181-93.
39. Plana, I., Lavoie, M.A., Battaglia, M., Achim, A.M. (2014). A meta-analysis and scoping review of social cognition performance in social phobia, posttraumatic stress disorder and other anxiety disorders. Journal of Anxiety Disorders, 28(2), 169-77.
40. Poljac, E., Montagne, B., de Haan, E.H. (2011). Reduced recognition of fear and sadness in post-traumatic stress disorder. Cortex, 47(8), 974-80.
41. Sancho Rossignol, A., LuthïFaivre, F., Suardi, F., Moser, D., Cordero, M., Rusconi Serpa, S., Schechter, D. (2010). Geneva Socio-demographic Questionnaire (GSQ). Geneva, Switzerland: Child and Adolescent Psychiatry Service, University of Geneva Hospitals.
42. Schechter, D.S., Coots, T., Zeanah, C.H., Davies, M., Coates, S.W., Trabka, K.A., Marshall, R.D., Liebowitz, M.R., Myers, M.M. (2005). Maternal mental representations of the child in an inner-city clinical sample: violence-related posttraumatic stress and reflective functioning. Attachment and Human Development, 7(3), 313-31.
43. Schechter, D.S., Moser, D.A., McCaw, J.E., Myers, M.M. (2014). Autonomic functioning in mothers with interpersonal violence-related posttraumatic stress disorder in response to separation-reunion. Developmental Psychobiology, 56(4), 748-60.
44. Schechter, D.S., Moser, D.A., Wang, Z., Marsh, R., Hao, X., Duan, Y., Yu, S., Gunter, B., Murphy, D., McCaw, J., Kangarlu, A., Willheim, E., Myers, M.M., Hofer, M.A.
45. Peterson, B.S. (2012). An fMRI study of the brain responses of traumatized mothers to viewing their toddlers during separation and play. Social Cognitive and Affective Neuroscience, 7(8), 969-79.
46. Schechter, D.S., Rusconi, S. (2014). Understanding how traumatised mothers process their toddlers' affective communication under stress: towards preventive intervention for families at high risk for intergenerational violence. In: Emde, R., Leuzinger-Bohleber, M., editors. Early Parenting Research and Prevention of Disorder: Psychoanalytic Research at Interdisciplinary Frontiers. London: Karnac Books.
47. Schechter, D.S., Willheim, E., Hinojosa, C., Scholfield-Kleinman, K., Turner, J.B., McCaw, J., Zeanah, C.H., Myers, M.M. (2010). Subjective and objective measures of parent-child relationship dysfunction, child separation distress, and joint attention. Psychiatry, 73(2), 130-44.
48. Shin, L.M., Orr, S.P., Carson, M.A., Rauch, S.L., Macklin, M.L., Lasko, N.B., Peters, P.M., Metzger, L.J., Dougherty, D.D., Cannistraro, P.A., Alpert, N.M., Fischman, A.J., Pitman, R.K. (2004). Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Archives of General Psychiatry, 61(2), 168-76.
49. Simmons, A.N., Paulus, M.P., Thorp, S.R., Matthews, S.C., Norman, S.B., Stein, M.B. (2008). Functional activation and neural networks in women with posttraumatic stress disorder related to intimate partner violence. Biological Psychiatry, 64(8), 681-90.
50. Sripada, R.K., King, A.P., Welsh, R.C., Garfinkel, S.N., Wang, X., Sripada, C.S., Liberzon, I. (2012). Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosomatic Medicine, 74(9), 904-11.
51. Steuwe, C., Daniels, J.K., Frewen, P.A., Densmore, M., Pannasch, S., Beblo, T., Reiss, J., Lanius, R.A. (2014). Effect of direct eye contact in PTSD related to interpersonal trauma: an fMRI study of activation of an innate alarm system. Social Cognitive and Affective Neuroscience, 9(1), 88-97.
52. Stevens, J.S., Jovanovic, T., Fani, N., Ely, T.D., Glover, E.M., Bradley, B., Ressler, K.J. (2013). Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder. Journal of Psychiatric Research, 47(10), 1469-78.
53. Strigo, I.A., Simmons, A.N., Matthews, S.C., Grimes, E.M., Allard, C.B., Reinhardt, L.E., Paulus, M.P., Stein, M.B. (2010). Neural correlates of altered pain response in women with posttraumatic stress disorder from intimate partner violence. Biological Psychiatry, 68(5), 442-50.
54. Sturge-Apple, M.L., Davies, P.T., Cicchetti, D., Manning, L.G. (2012). Interparental violence, maternal emotional unavailability and children's cortisol functioning in family contexts. Developmental Psychology, 48(1), 237-49.
55. Thomaes, K., Dorrepaal, E., Draijer, N., de Ruiter, M.B., Elzinga, B.M., Sjoerds, Z., van Balkom, A.J., Smit, J.H., Veltman, D.J. (2013). Increased anterior cingulate cortex and hippocampus activation in Complex PTSD during encoding of negative words. Social Cognitive and Affective Neuroscience, 8(2), 190-200.
56. Viinikainen, M., Jaaskelainen, I.P., Alexandrov, Y., Balk, M.H., Autti, T., Sams, M. (2010). Nonlinear relationship between emotional valence and brain activity: evidence of separate negative and positive valence dimensions. Human Brain Mapping, 31(7), 1030-40.
57. Vrticka, P., Bondolfi, G., Sander, D., Vuilleumier, P. (2012). The neural substrates of social emotion perception and regulation are modulated by adult attachment style. Social Neuroscience, 7(5), 473-93.
58. Whalley, M.G., Kroes, M.C., Huntley, Z., Rugg, M.D., Davis, S.W., Brewin, C.R. (2013). An fMRI investigation of posttraumatic flashbacks. Brain and Cognition, 81(1), 151-9.
59. World Medical Association (1999). Proposed revision of the Declaration of Helsinki. BME, 147, 18-22.
60. Zhu, L., Guo, X., Li, J., Zheng, L., Wang, Q., Yang, Z. (2012). Hippocampal activity is associated with self-descriptiveness effect in memory, whereas self-reference effect in memory depends on medial prefrontal activity. Hippocampus, 22(7), 1540-52.