-
1
-
-
0142106807
-
Role of polycystins in renal tubulogenesis
-
Boletta A, Germino GG. Role of polycystins in renal tubulogenesis. Trends Cell Biol. 2003;13:484-92.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 484-492
-
-
Boletta, A.1
Germino, G.G.2
-
2
-
-
33748748479
-
The polycystin 1-Cterminal fragment stimulates ERK-dependent spreading of renal epithelial cells
-
Joly D, Ishibe S, Nickel C, Yu Z, Somlo S, Cantley LG. The polycystin 1-Cterminal fragment stimulates ERK-dependent spreading of renal epithelial cells. J Biol Chem. 2006;281:26329-39.
-
(2006)
J Biol Chem
, vol.281
, pp. 26329-26339
-
-
Joly, D.1
Ishibe, S.2
Nickel, C.3
Yu, Z.4
Somlo, S.5
Cantley, L.G.6
-
3
-
-
77954510897
-
Emerging evidence of a link between the polycystins and the mTOR pathways
-
Boletta A. Emerging evidence of a link between the polycystins and the mTOR pathways. Pathogenetics. 2009;2:6.
-
(2009)
Pathogenetics
, vol.2
, pp. 6
-
-
Boletta, A.1
-
4
-
-
28844435249
-
The nanomechanics of polycystin-1 extracellular region
-
Qian F, Wei W, Germino G, Oberhauser A. The nanomechanics of polycystin-1 extracellular region. J Biol Chem. 2005;280:40723-30.
-
(2005)
J Biol Chem
, vol.280
, pp. 40723-40730
-
-
Qian, F.1
Wei, W.2
Germino, G.3
Oberhauser, A.4
-
5
-
-
19444372522
-
The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction
-
Forman JR, Qamar S, Paci E, Sandford RN, Clarke J. The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction. J Mol Biol. 2005;349:861-71.
-
(2005)
J Mol Biol
, vol.349
, pp. 861-871
-
-
Forman, J.R.1
Qamar, S.2
Paci, E.3
Sandford, R.N.4
Clarke, J.5
-
6
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet. 2003;33:129-37.
-
(2003)
Nat Genet
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
-
7
-
-
84890352250
-
Direct recording and molecular identification of the calcium channel of primary cilia
-
DeCaen PG, Delling M, Vien TN, Clapham DE. Direct recording and molecular identification of the calcium channel of primary cilia. Nature. 2013;504:315-8.
-
(2013)
Nature
, vol.504
, pp. 315-318
-
-
DeCaen, P.G.1
Delling, M.2
Vien, T.N.3
Clapham, D.E.4
-
8
-
-
67650544382
-
Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells
-
Streets AJ, Wagner BE, Harris PC, Ward CJ, Ong AC. Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells. J Cell Sci. 2009;122:1410-7.
-
(2009)
J Cell Sci
, vol.122
, pp. 1410-1417
-
-
Streets, A.J.1
Wagner, B.E.2
Harris, P.C.3
Ward, C.J.4
Ong, A.C.5
-
9
-
-
34948834648
-
Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion
-
Boca M, D'Amato L, Distefano G, Polishchuk RS, Germino GG, Boletta A. Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion. Mol Biol Cell. 2007;18:4050-61.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 4050-4061
-
-
Boca, M.1
D'Amato, L.2
Distefano, G.3
Polishchuk, R.S.4
Germino, G.G.5
Boletta, A.6
-
10
-
-
0032831465
-
The PKD1 gene product, "polycystin-1, " is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia
-
Wilson PD, Geng L, Li X, Burrow CR. The PKD1 gene product, "polycystin-1, " is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia. Lab Invest. 1999;79:1311-23.
-
(1999)
Lab Invest
, vol.79
, pp. 1311-1323
-
-
Wilson, P.D.1
Geng, L.2
Li, X.3
Burrow, C.R.4
-
11
-
-
79960972769
-
c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation
-
Elliott J, Zheleznova NN, Wilson PD. c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation. Am J Physiol Cell Physiol. 2011;301:C522-9.
-
(2011)
Am J Physiol Cell Physiol
, vol.301
, pp. C522-C529
-
-
Elliott, J.1
Zheleznova, N.N.2
Wilson, P.D.3
-
14
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 1995;377:539-44.
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
-
15
-
-
0032820782
-
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
-
Sieg DJ, Hauck CR, Schlaepfer DD. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci. 1999;112(Pt 16):2677-91.
-
(1999)
J Cell Sci
, vol.112
, pp. 2677-2691
-
-
Sieg, D.J.1
Hauck, C.R.2
Schlaepfer, D.D.3
-
16
-
-
0033666291
-
Paxillin and focal adhesion signalling
-
Turner CE. Paxillin and focal adhesion signalling. Nat Cell Biol. 2000;2:E231-6.
-
(2000)
Nat Cell Biol
, vol.2
, pp. E231-E236
-
-
Turner, C.E.1
-
17
-
-
2442606429
-
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility
-
Subauste MC, Pertz O, Adamson ED, Turner CE, Junger S, Hahn KM. Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J Cell Biol. 2004;165:371-81.
-
(2004)
J Cell Biol
, vol.165
, pp. 371-381
-
-
Subauste, M.C.1
Pertz, O.2
Adamson, E.D.3
Turner, C.E.4
Junger, S.5
Hahn, K.M.6
-
18
-
-
84886654516
-
Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis
-
Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, et al. Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis. Nat Commun. 2013;4:2658.
-
(2013)
Nat Commun
, vol.4
, pp. 2658
-
-
Castelli, M.1
Boca, M.2
Chiaravalli, M.3
Ramalingam, H.4
Rowe, I.5
Distefano, G.6
-
19
-
-
84899956827
-
Polycystin signaling is required for directed endothelial cell migration and lymphatic development
-
Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, et al. Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Rep. 2014;7:634-44.
-
(2014)
Cell Rep
, vol.7
, pp. 634-644
-
-
Outeda, P.1
Huso, D.L.2
Fisher, S.A.3
Halushka, M.K.4
Kim, H.5
Qian, F.6
-
20
-
-
84898815152
-
Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex
-
Yao G, Su X, Nguyen V, Roberts K, Li X, Takakura A, et al. Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex. Hum Mol Genet. 2014;23:2769-79.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 2769-2779
-
-
Yao, G.1
Su, X.2
Nguyen, V.3
Roberts, K.4
Li, X.5
Takakura, A.6
-
21
-
-
0036175934
-
The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells
-
Nickel C, Benzing T, Sellin L, Gerke P, Karihaloo A, Liu ZX, et al. The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells. J Clin Invest. 2002;109:481-9.
-
(2002)
J Clin Invest
, vol.109
, pp. 481-489
-
-
Nickel, C.1
Benzing, T.2
Sellin, L.3
Gerke, P.4
Karihaloo, A.5
Liu, Z.X.6
-
22
-
-
0033635231
-
Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells
-
Boletta A, Qian F, Onuchic LF, Bhunia AK, Phakdeekitcharoen B, Hanaoka K, et al. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Mol Cell. 2000;6:1267-73.
-
(2000)
Mol Cell
, vol.6
, pp. 1267-1273
-
-
Boletta, A.1
Qian, F.2
Onuchic, L.F.3
Bhunia, A.K.4
Phakdeekitcharoen, B.5
Hanaoka, K.6
-
23
-
-
20444370219
-
Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
-
Ezratty EJ, Partridge MA, Gundersen GG. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat Cell Biol. 2005;7:581-90.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 581-590
-
-
Ezratty, E.J.1
Partridge, M.A.2
Gundersen, G.G.3
-
24
-
-
84889587778
-
The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration
-
Palamidessi A, Frittoli E, Ducano N, Offenhauser N, Sigismund S, Kajiho H, et al. The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration. Curr Biol. 2013;23:2355-64.
-
(2013)
Curr Biol
, vol.23
, pp. 2355-2364
-
-
Palamidessi, A.1
Frittoli, E.2
Ducano, N.3
Offenhauser, N.4
Sigismund, S.5
Kajiho, H.6
-
25
-
-
84869137612
-
Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration
-
Rosse C, Boeckeler K, Linch M, Radtke S, Frith D, Barnouin K, et al. Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration. J Cell Sci. 2012;125:3733-8.
-
(2012)
J Cell Sci
, vol.125
, pp. 3733-3738
-
-
Rosse, C.1
Boeckeler, K.2
Linch, M.3
Radtke, S.4
Frith, D.5
Barnouin, K.6
-
26
-
-
34447538483
-
Cellular characterization of a novel focal adhesion kinase inhibitor
-
Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, et al. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem. 2007;282:14845-52.
-
(2007)
J Biol Chem
, vol.282
, pp. 14845-14852
-
-
Slack-Davis, J.K.1
Martin, K.H.2
Tilghman, R.W.3
Iwanicki, M.4
Ung, E.J.5
Autry, C.6
-
27
-
-
3142763039
-
Actin and microtubules in cell motility: which one is in control?
-
Etienne-Manneville S. Actin and microtubules in cell motility: which one is in control? Traffic. 2004;5:470-7.
-
(2004)
Traffic
, vol.5
, pp. 470-477
-
-
Etienne-Manneville, S.1
-
28
-
-
58249086114
-
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
-
Gardel ML, Sabass B, Ji L, Danuser G, Schwarz US, Waterman CM. Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed. J Cell Biol. 2008;183:999-1005.
-
(2008)
J Cell Biol
, vol.183
, pp. 999-1005
-
-
Gardel, M.L.1
Sabass, B.2
Ji, L.3
Danuser, G.4
Schwarz, U.S.5
Waterman, C.M.6
-
29
-
-
33645458872
-
Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway
-
Boca M, Distefano G, Qian F, Bhunia AK, Germino GG, Boletta A. Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway. J Am Soc Nephrol. 2006;17:637-47.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 637-647
-
-
Boca, M.1
Distefano, G.2
Qian, F.3
Bhunia, A.K.4
Germino, G.G.5
Boletta, A.6
-
30
-
-
67649878597
-
Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis
-
Karner CM, Chirumamilla R, Aoki S, Igarashi P, Wallingford JB, Carroll TJ. Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat Genet. 2009;41:793-9.
-
(2009)
Nat Genet
, vol.41
, pp. 793-799
-
-
Karner, C.M.1
Chirumamilla, R.2
Aoki, S.3
Igarashi, P.4
Wallingford, J.B.5
Carroll, T.J.6
-
31
-
-
84870478180
-
Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension
-
Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, et al. Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Nat Genet. 2012;44:1382-7.
-
(2012)
Nat Genet
, vol.44
, pp. 1382-1387
-
-
Lienkamp, S.S.1
Liu, K.2
Karner, C.M.3
Carroll, T.J.4
Ronneberger, O.5
Wallingford, J.B.6
-
32
-
-
70349612312
-
A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus
-
Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A. A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS One. 2009;4:e7137.
-
(2009)
PLoS One
, vol.4
-
-
Wodarczyk, C.1
Rowe, I.2
Chiaravalli, M.3
Pema, M.4
Qian, F.5
Boletta, A.6
-
33
-
-
65449176538
-
Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1
-
Distefano G, Boca M, Rowe I, Wodarczyk C, Ma L, Piontek KB, et al. Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1. Mol Cell Biol. 2009;29:2359-71.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2359-2371
-
-
Distefano, G.1
Boca, M.2
Rowe, I.3
Wodarczyk, C.4
Ma, L.5
Piontek, K.B.6
|