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Volumn 14, Issue 1, 2014, Pages

Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat

Author keywords

Acute myocardial infarction; PCSK9; Rat

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 1ALPHA; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PROTEIN PCSK9; SERINE PROTEINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; PCSK9 PROTEIN, RAT;

EID: 84964695749     PISSN: None     EISSN: 14712261     Source Type: Journal    
DOI: 10.1186/1471-2261-14-192     Document Type: Article
Times cited : (46)

References (38)
  • 3
    • 84883245777 scopus 로고    scopus 로고
    • Acute myocardial infarction in an 8-year old male child with homozygous familiar hypercholesterolemia: laboratory findings and response to lipidlowering drugs
    • Wu NQ, Guo YL, Xu RX, Liu J, Zhu CG, Jiang LX, Li JJ: Acute myocardial infarction in an 8-year old male child with homozygous familiar hypercholesterolemia: laboratory findings and response to lipidlowering drugs. Clin Lab 2013, 59:901-907.
    • (2013) Clin Lab , vol.59 , pp. 901-907
    • Wu, N.Q.1    Guo, Y.L.2    Xu, R.X.3    Liu, J.4    Zhu, C.G.5    Jiang, L.X.6    Li, J.J.7
  • 4
    • 84868628467 scopus 로고    scopus 로고
    • Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication
    • Benn M, Watts GF, Tybjaerg-Hansen A, Nordestgaard BG: Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication. J Clin Endocrinol Metab 2012, 97:3956-3964.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 3956-3964
    • Benn, M.1    Watts, G.F.2    Tybjaerg-Hansen, A.3    Nordestgaard, B.G.4
  • 6
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH: Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006, 354:1264-1272.
    • (2006) N Engl J Med , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley, T.H.3    Hobbs, H.H.4
  • 8
    • 84885447918 scopus 로고    scopus 로고
    • Targeting the Proprotein Convertase Subtilisin/Kexin Type 9 for the Treatment of Dyslipidemia and Atherosclerosis
    • Urban D, Pöss J, Böhm M, Laufs U: Targeting the Proprotein Convertase Subtilisin/Kexin Type 9 for the Treatment of Dyslipidemia and Atherosclerosis. J Am Coll Cardiol 2013, 62:1401-1408.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1401-1408
    • Urban, D.1    Pöss, J.2    Böhm, M.3    Laufs, U.4
  • 9
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
    • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L, INTERHEART Study Investigators: Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004, 364:937-952.
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5    Lanas, F.6    McQueen, M.7    Budaj, A.8    Pais, P.9    Varigos, J.10    Lisheng, L.11
  • 10
    • 84861319096 scopus 로고    scopus 로고
    • The modification of serum lipids after acute coronary syndrome and importance in clinical practice
    • Balci B: The modification of serum lipids after acute coronary syndrome and importance in clinical practice. Curr Cardiol Rev 2011, 7:272-276.
    • (2011) Curr Cardiol Rev , vol.7 , pp. 272-276
    • Balci, B.1
  • 11
    • 84884566227 scopus 로고    scopus 로고
    • Rapid effects of different lipid-lowering drugs on PCSK9 in humans
    • Liu J, Guo YL, Xu RX, Li JJ: Rapid effects of different lipid-lowering drugs on PCSK9 in humans. Clin Lipidol 2013, 8:519-524.
    • (2013) Clin Lipidol , vol.8 , pp. 519-524
    • Liu, J.1    Guo, Y.L.2    Xu, R.X.3    Li, J.J.4
  • 12
    • 77949525476 scopus 로고    scopus 로고
    • Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels
    • Troutt JS, Alborn WE, Cao G, Konrad RJ: Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels. J Lipid Res 2010, 51:345-351.
    • (2010) J Lipid Res , vol.51 , pp. 345-351
    • Troutt, J.S.1    Alborn, W.E.2    Cao, G.3    Konrad, R.J.4
  • 13
    • 78149300891 scopus 로고    scopus 로고
    • Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans
    • Browning JD, Horton JD: Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans. J Lipid Res 2010, 51:3359-3363.
    • (2010) J Lipid Res , vol.51 , pp. 3359-3363
    • Browning, J.D.1    Horton, J.D.2
  • 15
    • 82955232910 scopus 로고    scopus 로고
    • Increased serum PCSK9 concentrations are associated with periodontal infection but do not correlate with LDL cholesterol concentration
    • Miyazawa H, Honda T, Miyauchi S, Domon H, Okui T, Nakajima T, Tabeta K, Yamazaki K: Increased serum PCSK9 concentrations are associated with periodontal infection but do not correlate with LDL cholesterol concentration. Clin Chim Acta 2012, 413:154-159.
    • (2012) Clin Chim Acta , vol.413 , pp. 154-159
    • Miyazawa, H.1    Honda, T.2    Miyauchi, S.3    Domon, H.4    Okui, T.5    Nakajima, T.6    Tabeta, K.7    Yamazaki, K.8
  • 18
    • 18944392912 scopus 로고    scopus 로고
    • A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis
    • Chen SN, Ballantyne CM, Gotto AM Jr, Tan Y, Willerson JT, Marian AJ: A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol 2005, 45:1611-1619.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1611-1619
    • Chen, S.N.1    Ballantyne, C.M.2    Gotto, A.M.3    Tan, Y.4    Willerson, J.T.5    Marian, A.J.6
  • 19
    • 36148954322 scopus 로고    scopus 로고
    • Adenoviral gene transfer of sphingosine kinase 1 protects heart against ischemia/reperfusion-induced injury and attenuates its postischemic failure
    • Duan HF, Wang H, Yi J, Liu HJ, Zhang QW, Li LB, Zhang T, Lu Y, Wu CT, Wang LS: Adenoviral gene transfer of sphingosine kinase 1 protects heart against ischemia/reperfusion-induced injury and attenuates its postischemic failure. Hum Gene Ther 2007, 18:1119-1128.
    • (2007) Hum Gene Ther , vol.18 , pp. 1119-1128
    • Duan, H.F.1    Wang, H.2    Yi, J.3    Liu, H.J.4    Zhang, Q.W.5    Li, L.B.6    Zhang, T.7    Lu, Y.8    Wu, C.T.9    Wang, L.S.10
  • 20
    • 84890264853 scopus 로고    scopus 로고
    • Short-Term Impact of Low-Dose Atorvastatin on Serum Proprotein Convertase Subtilisin/Kexin Type 9
    • Guo YL, Liu J, Xu RX, Zhu CG, Wu NQ, Jiang LX, Li JJ: Short-Term Impact of Low-Dose Atorvastatin on Serum Proprotein Convertase Subtilisin/Kexin Type 9. Clin Drug Investig 2013, 33:877-883.
    • (2013) Clin Drug Investig , vol.33 , pp. 877-883
    • Guo, Y.L.1    Liu, J.2    Xu, R.X.3    Zhu, C.G.4    Wu, N.Q.5    Jiang, L.X.6    Li, J.J.7
  • 21
    • 38949137409 scopus 로고    scopus 로고
    • Sterol dependent regulation of proprotein convertase subtilisin/kexin type 9 by sterol regulatory element binding-protein 2
    • Jeong HJ, Lee HS, Kim KS, Kim YK, Yoon D, Park SW: Sterol dependent regulation of proprotein convertase subtilisin/kexin type 9 by sterol regulatory element binding-protein 2. J Lipid Res 2008, 49:399-409.
    • (2008) J Lipid Res , vol.49 , pp. 399-409
    • Jeong, H.J.1    Lee, H.S.2    Kim, K.S.3    Kim, Y.K.4    Yoon, D.5    Park, S.W.6
  • 22
    • 70350389729 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine
    • Li H, Dong B, Park SW, Lee HS, Chen W, Liu J: Hepatocyte nuclear factor 1 alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. J Biol Chem 2009, 284:28885-28895.
    • (2009) J Biol Chem , vol.284 , pp. 28885-28895
    • Li, H.1    Dong, B.2    Park, S.W.3    Lee, H.S.4    Chen, W.5    Liu, J.6
  • 23
    • 82255173973 scopus 로고    scopus 로고
    • Inflammation in coronary artery diseases
    • Li JJ: Inflammation in coronary artery diseases. Chin Med J (Engl) 2011, 124:3568-3575.
    • (2011) Chin Med J (Engl) , vol.124 , pp. 3568-3575
    • Li, J.J.1
  • 24
    • 84866405805 scopus 로고    scopus 로고
    • Inflammation in coronary artery disease and acute myocardial infarction-is the stage set for novel therapies?
    • Klingenberg R, Luscher TF: Inflammation in coronary artery disease and acute myocardial infarction-is the stage set for novel therapies? Curr Pharm Des 2012, 18:4358-4369.
    • (2012) Curr Pharm Des , vol.18 , pp. 4358-4369
    • Klingenberg, R.1    Luscher, T.F.2
  • 26
    • 33749022762 scopus 로고    scopus 로고
    • Interaction between Chlamydia pneumoniae seropositivity, inflammation and risk factors for atherosclerosis inpatients with severe coronary stenosis
    • Yavuz MT, Yavuz O, Yazici M, Guler S, Ozhan H, Albayrak S, Coskun A: Interaction between Chlamydia pneumoniae seropositivity, inflammation and risk factors for atherosclerosis inpatients with severe coronary stenosis. Scand J Clin Lab Invest 2006, 66:523-534.
    • (2006) Scand J Clin Lab Invest , vol.66 , pp. 523-534
    • Yavuz, M.T.1    Yavuz, O.2    Yazici, M.3    Guler, S.4    Ozhan, H.5    Albayrak, S.6    Coskun, A.7
  • 27
    • 11844252543 scopus 로고    scopus 로고
    • Enhanced response of blood monocytes to C-reactive protein in patients with unstable angina
    • Li JJ, Wang HR, Huang CX, Xue JL, Li GS: Enhanced response of blood monocytes to C-reactive protein in patients with unstable angina. Clin Chim Acta 2004, 352:127-133.
    • (2004) Clin Chim Acta , vol.352 , pp. 127-133
    • Li, J.J.1    Wang, H.R.2    Huang, C.X.3    Xue, J.L.4    Li, G.S.5
  • 28
    • 3042730793 scopus 로고    scopus 로고
    • Activation of nuclear factor-?B and correlation with elevated plasma C-reactive protein in patients with unstable angina
    • Li JJ, Fang CH, Cheng MZ, Chen X, Lee SW: Activation of nuclear factor-?B and correlation with elevated plasma C-reactive protein in patients with unstable angina. Heart Lung Circ 2004, 13:173-178.
    • (2004) Heart Lung Circ , vol.13 , pp. 173-178
    • Li, J.J.1    Fang, C.H.2    Cheng, M.Z.3    Chen, X.4    Lee, S.W.5
  • 31
    • 84887417117 scopus 로고    scopus 로고
    • Shenyuan, an extract of American Ginseng and Corydalis Tuber formula, attenuates cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and oxidative stress in a porcine model of acute myocardial infarction
    • Zhu XY, Zhang ZL, Li P, Liang WY, Feng XR, Liu ML: Shenyuan, an extract of American Ginseng and Corydalis Tuber formula, attenuates cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and oxidative stress in a porcine model of acute myocardial infarction. J Ethnopharmacol 2013, 150:672-681.
    • (2013) J Ethnopharmacol , vol.150 , pp. 672-681
    • Zhu, X.Y.1    Zhang, Z.L.2    Li, P.3    Liang, W.Y.4    Feng, X.R.5    Liu, M.L.6
  • 32
    • 79959268253 scopus 로고    scopus 로고
    • PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke
    • Rousselet E, Marcinkiewicz J, Kriz J, Zhou A, Hatten ME, Prat A, Seidah NG: PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res 2011, 52:1383-1391.
    • (2011) J Lipid Res , vol.52 , pp. 1383-1391
    • Rousselet, E.1    Marcinkiewicz, J.2    Kriz, J.3    Zhou, A.4    Hatten, M.E.5    Prat, A.6    Seidah, N.G.7
  • 33
    • 83555173282 scopus 로고    scopus 로고
    • PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway
    • Wu CY, Tang ZH, Jiang L, Li XF, Jiang ZS, Liu LS: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. Mol Cell Biochem 2012, 359:347-358.
    • (2012) Mol Cell Biochem , vol.359 , pp. 347-358
    • Wu, C.Y.1    Tang, Z.H.2    Jiang, L.3    Li, X.F.4    Jiang, Z.S.5    Liu, L.S.6
  • 34
    • 3042606551 scopus 로고    scopus 로고
    • Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host
    • Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C: Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res 2004, 45:1169-1196.
    • (2004) J Lipid Res , vol.45 , pp. 1169-1196
    • Khovidhunkit, W.1    Kim, M.S.2    Memon, R.A.3    Shigenaga, J.K.4    Moser, A.H.5    Feingold, K.R.6    Grunfeld, C.7
  • 35
    • 84855964405 scopus 로고    scopus 로고
    • Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels
    • Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S, Corsini A, Catapano AL: Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels. Atherosclerosis 2012, 220:381-386.
    • (2012) Atherosclerosis , vol.220 , pp. 381-386
    • Ferri, N.1    Tibolla, G.2    Pirillo, A.3    Cipollone, F.4    Mezzetti, A.5    Pacia, S.6    Corsini, A.7    Catapano, A.L.8
  • 36
    • 79958048849 scopus 로고    scopus 로고
    • Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction
    • Berti V, Sciagrà R, Acampa W, Ricci F, Cerisano G, Gallicchio R, Vigorito C, Pupi A, Cuocolo A: Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction. Eur J Nucl Med Mol Imaging 2011, 38:1124-1131.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 1124-1131
    • Berti, V.1    Sciagrà, R.2    Acampa, W.3    Ricci, F.4    Cerisano, G.5    Gallicchio, R.6    Vigorito, C.7    Pupi, A.8    Cuocolo, A.9
  • 37
    • 84873315682 scopus 로고    scopus 로고
    • Alteration of relation of atherogenic lipoprotein cholesterol to apolipoprotein B by intensive statin therapy in patients with acute coronary syndrome (from the Limiting UNdertreatment of lipids in ACS With Rosuvastatin [LUNAR] Trial)
    • Ballantyne CM, Pitt B, Loscalzo J, Cain VA, Raichlen JS: Alteration of relation of atherogenic lipoprotein cholesterol to apolipoprotein B by intensive statin therapy in patients with acute coronary syndrome (from the Limiting UNdertreatment of lipids in ACS With Rosuvastatin [LUNAR] Trial). Am J Cardiol 2013, 111:506-509.
    • (2013) Am J Cardiol , vol.111 , pp. 506-509
    • Ballantyne, C.M.1    Pitt, B.2    Loscalzo, J.3    Cain, V.A.4    Raichlen, J.S.5


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