메뉴 건너뛰기




Volumn 11, Issue 4, 2016, Pages

Mutational profiles reveal an aberrant TGF-β-CEA regulated pathway in colon adenomas

(32)  Chen, Jian a   Raju, Gottumukkala S a   Jogunoori, Wilma b   Menon, Vipin a   Majumdar, Avijit a   Chen, Jiun Sheng a   Gi, Young Jin a   Jeong, Yun Seong a   Phan, Liem a   Belkin, Mitchell b   Gu, Shoujun c   Kundra, Suchin a   Mistry, Nipun A a   Zhang, Jianping a   Su, Xiaoping a   Li, Shulin a   Lin, Sue Hwa a   Javle, Milind a   McMurray, John S a   Rahlfs, Thomas F a   more..


Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TUMOR MARKER;

EID: 84964669930     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0153933     Document Type: Article
Times cited : (18)

References (39)
  • 2
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • PMID: 21685461
    • Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011; 61(4):212-36. doi: 10.3322/caac.20121 PMID: 21685461
    • (2011) CA Cancer J Clin , vol.61 , Issue.4 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 8
    • 84921288028 scopus 로고    scopus 로고
    • Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions
    • PMID: 25554788
    • Tomasetti C, Vogelstein B. Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science. 2015; 347(6217):78-81. doi: 10.1126/science.1260825 PMID: 25554788
    • (2015) Science , vol.347 , Issue.6217 , pp. 78-81
    • Tomasetti, C.1    Vogelstein, B.2
  • 9
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • PMID: 2188735
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990; 61(5):759-67. PMID: 2188735
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 10
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • PMID: 23540688
    • Garraway LA, Lander ES. Lessons from the cancer genome. Cell. 2013; 153(1):17-37. doi: 10.1016/j. cell.2013.03.002 PMID: 23540688
    • (2013) Cell , vol.153 , Issue.1 , pp. 17-37
    • Garraway, L.A.1    Lander, E.S.2
  • 11
    • 64749094310 scopus 로고    scopus 로고
    • The cancer genome
    • PMID: 19360079
    • Stratton MR, Campbell PJ, Futreal PA. The cancer genome. Nature. 2009; 458(7239):719-24. doi: 10.1038/nature07943 PMID: 19360079
    • (2009) Nature , vol.458 , Issue.7239 , pp. 719-724
    • Stratton, M.R.1    Campbell, P.J.2    Futreal, P.A.3
  • 12
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • PMID: 22810696
    • Cancer Genome Atlas N. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012; 487(7407):330-7. doi: 10.1038/nature11252 PMID: 22810696
    • (2012) Nature , vol.487 , Issue.7407 , pp. 330-337
    • Cancer Genome Atlas N.1
  • 13
    • 84877600884 scopus 로고    scopus 로고
    • Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
    • PMID: 23584090
    • De Sousa EMF, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, et al. Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nature medicine. 2013; 19(5):614-8. doi: 10.1038/nm.3174 PMID: 23584090
    • (2013) Nature Medicine , vol.19 , Issue.5 , pp. 614-618
    • De Sousa, E.M.F.1    Wang, X.2    Jansen, M.3    Fessler, E.4    Trinh, A.5    De Rooij, L.P.6
  • 14
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • PMID: 23584089
    • Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nature medicine. 2013; 19(5):619-25. doi: 10.1038/nm.3175 PMID: 23584089
    • (2013) Nature Medicine , vol.19 , Issue.5 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, K.3    Collisson, E.A.4    Gibb, W.J.5    Wullschleger, S.6
  • 15
    • 84895768701 scopus 로고    scopus 로고
    • RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers
    • PMID: 24533081
    • Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, et al. RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers. PloS one. 2014; 9(2):e88367. doi: 10.1371/journal.pone.0088367 PMID: 24533081
    • (2014) PloS One , vol.9 , Issue.2 , pp. e88367
    • Delker, D.A.1    McGettigan, B.M.2    Kanth, P.3    Pop, S.4    Neklason, D.W.5    Bronner, M.P.6
  • 16
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • PMID: 17932254
    • Wood LD, Parsons DW, Jones S, Lin J, Sjoblom T, Leary RJ, et al. The genomic landscapes of human breast and colorectal cancers. Science. 2007; 318(5853):1108-13. PMID: 17932254
    • (2007) Science , vol.318 , Issue.5853 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3    Lin, J.4    Sjoblom, T.5    Leary, R.J.6
  • 18
    • 84944040819 scopus 로고    scopus 로고
    • Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors
    • PMID: 26440895
    • Paz-Yaacov N, Bazak L, Buchumenski I, Porath HT, Danan-Gotthold M, Knisbacher BA, et al. Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors. Cell Rep. 2015; 13 (2):267-76. doi: 10.1016/j.celrep.2015.08.080 PMID: 26440895
    • (2015) Cell Rep , vol.13 , Issue.2 , pp. 267-276
    • Paz-Yaacov, N.1    Bazak, L.2    Buchumenski, I.3    Porath, H.T.4    Danan-Gotthold, M.5    Knisbacher, B.A.6
  • 19
    • 77449130761 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer
    • e3. PMID: 20420947
    • Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology. 2010; 138 (6):2073-87 e3. doi: 10.1053/j.gastro.2009.12.064 PMID: 20420947
    • (2010) Gastroenterology , vol.138 , Issue.6 , pp. 2073-2087
    • Boland, C.R.1    Goel, A.2
  • 20
    • 84891852738 scopus 로고    scopus 로고
    • Self-renewal as a therapeutic target in human colorectal cancer
    • PMID: 24292392
    • Kreso A, van Galen P, Pedley NM, Lima-Fernandes E, Frelin C, Davis T, et al. Self-renewal as a therapeutic target in human colorectal cancer. Nature medicine. 2014; 20(1):29-36. doi: 10.1038/nm.3418 PMID: 24292392
    • (2014) Nature Medicine , vol.20 , Issue.1 , pp. 29-36
    • Kreso, A.1    Van Galen, P.2    Pedley, N.M.3    Lima-Fernandes, E.4    Frelin, C.5    Davis, T.6
  • 21
    • 0023177138 scopus 로고
    • Isolation and characterization of fulllength functional cDNA clones for human carcinoembryonic antigen
    • PMID: 3670312
    • Beauchemin N, Benchimol S, Cournoyer D, Fuks A, Stanners CP. Isolation and characterization of fulllength functional cDNA clones for human carcinoembryonic antigen. Mol Cell Biol. 1987; 7(9):3221-30. PMID: 3670312
    • (1987) Mol Cell Biol , vol.7 , Issue.9 , pp. 3221-3230
    • Beauchemin, N.1    Benchimol, S.2    Cournoyer, D.3    Fuks, A.4    Stanners, C.P.5
  • 22
    • 0024558306 scopus 로고
    • Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
    • PMID: 2702691
    • Benchimol S, Fuks A, Jothy S, Beauchemin N, Shirota K, Stanners CP. Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell. 1989; 57(2):327-34. PMID: 2702691
    • (1989) Cell , vol.57 , Issue.2 , pp. 327-334
    • Benchimol, S.1    Fuks, A.2    Jothy, S.3    Beauchemin, N.4    Shirota, K.5    Stanners, C.P.6
  • 23
    • 84890442740 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis
    • PMID: 23903773
    • Beauchemin N, Arabzadeh A. Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis. Cancer metastasis reviews. 2013; 32(3-4):643-71. doi: 10.1007/s10555-013-9444-6 PMID: 23903773
    • (2013) Cancer Metastasis Reviews , vol.32 , Issue.3-4 , pp. 643-671
    • Beauchemin, N.1    Arabzadeh, A.2
  • 24
    • 78049300012 scopus 로고    scopus 로고
    • Carcinoembryonic antigen interacts with TGF-β receptor and inhibits TGF-β signaling in colorectal cancers
    • PMID: 20889724
    • Li Y, Cao H, Jiao Z, Pakala SB, Sirigiri DN, Li W, et al. Carcinoembryonic antigen interacts with TGF-β receptor and inhibits TGF-β signaling in colorectal cancers. Cancer Res. 2010; 70(20):8159-68. doi: 10.1158/0008-5472.CAN-10-1073 PMID: 20889724
    • (2010) Cancer Res , vol.70 , Issue.20 , pp. 8159-8168
    • Li, Y.1    Cao, H.2    Jiao, Z.3    Pakala, S.B.4    Sirigiri, D.N.5    Li, W.6
  • 25
    • 34250353411 scopus 로고    scopus 로고
    • Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling
    • PMID: 17510406
    • Samara RN, Laguinge LM, Jessup JM. Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling. Cancer Res. 2007; 67(10):4774-82. PMID: 17510406
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4774-4782
    • Samara, R.N.1    Laguinge, L.M.2    Jessup, J.M.3
  • 27
    • 0034644472 scopus 로고    scopus 로고
    • TGF-β signaling in growth control, cancer, and heritable disorders
    • PMID: 11057902
    • Massague J, Blain SW, Lo RS. TGF-β signaling in growth control, cancer, and heritable disorders. Cell. 2000; 103(2):295-309. PMID: 11057902
    • (2000) Cell , vol.103 , Issue.2 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 28
    • 84865778024 scopus 로고    scopus 로고
    • Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma
    • PMID: 22710573
    • Majumdar A, Curley SA, Wu X, Brown P, Hwang JP, Shetty K, et al. Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2012; 9(9):530-8. doi: 10.1038/nrgastro.2012.114 PMID: 22710573
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , Issue.9 , pp. 530-538
    • Majumdar, A.1    Curley, S.A.2    Wu, X.3    Brown, P.4    Hwang, J.P.5    Shetty, K.6
  • 30
    • 20144378766 scopus 로고    scopus 로고
    • Transforming growth factor-β suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis
    • PMID: 15899814
    • Tang Y, Katuri V, Srinivasan R, Fogt F, Redman R, Anand G, et al. Transforming growth factor-β suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis. Cancer Res. 2005; 65(10):4228-37. PMID: 15899814
    • (2005) Cancer Res , vol.65 , Issue.10 , pp. 4228-4237
    • Tang, Y.1    Katuri, V.2    Srinivasan, R.3    Fogt, F.4    Redman, R.5    Anand, G.6
  • 31
    • 24644458638 scopus 로고    scopus 로고
    • The role of TGF-β and Wnt signaling in gastrointestinal stem cells and cancer
    • PMID: 16123810
    • Mishra L, Shetty K, Tang Y, Stuart A, Byers SW. The role of TGF-β and Wnt signaling in gastrointestinal stem cells and cancer. Oncogene. 2005; 24(37):5775-89. PMID: 16123810
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5775-5789
    • Mishra, L.1    Shetty, K.2    Tang, Y.3    Stuart, A.4    Byers, S.W.5
  • 32
    • 77953631564 scopus 로고    scopus 로고
    • Mutations in TGF-β-RII and BAX mediate tumor progression in the later stages of colorectal cancer with microsatellite instability
    • PMID: 20565851
    • Yashiro M, Hirakawa K, Boland CR. Mutations in TGF-β-RII and BAX mediate tumor progression in the later stages of colorectal cancer with microsatellite instability. BMC Cancer. 2010; 10:303. doi: 10.1186/1471-2407-10-303 PMID: 20565851
    • (2010) BMC Cancer , vol.10 , pp. 303
    • Yashiro, M.1    Hirakawa, K.2    Boland, C.R.3
  • 33
    • 84890442740 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis
    • Beauchemin N, Arabzadeh A. Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis. Cancer Metastasis Rev. 2013.
    • (2013) Cancer Metastasis Rev
    • Beauchemin, N.1    Arabzadeh, A.2
  • 34
    • 84899559485 scopus 로고    scopus 로고
    • Characterizing CEACAM5 interaction with CD8alpha and CD1d in intestinal homeostasis
    • PMID: 24104458
    • Roda G, Jianyu X, Park MS, DeMarte L, Hovhannisyan Z, Couri R, et al. Characterizing CEACAM5 interaction with CD8alpha and CD1d in intestinal homeostasis. Mucosal Immunol. 2014; 7(3):615-24. doi: 10.1038/mi.2013.80 PMID: 24104458
    • (2014) Mucosal Immunol , vol.7 , Issue.3 , pp. 615-624
    • Roda, G.1    Jianyu, X.2    Park, M.S.3    DeMarte, L.4    Hovhannisyan, Z.5    Couri, R.6
  • 35
    • 84869187290 scopus 로고    scopus 로고
    • The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction
    • PMID: 23123061
    • Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, et al. The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction. Immunity. 2012; 37(5):930-46. doi: 10.1016/j.immuni.2012.07.016 PMID: 23123061
    • (2012) Immunity , vol.37 , Issue.5 , pp. 930-946
    • Chen, L.1    Chen, Z.2    Baker, K.3    Halvorsen, E.M.4    Da Cunha, A.P.5    Flak, M.B.6
  • 36
    • 84916230879 scopus 로고    scopus 로고
    • Tumor and endothelial cellderived microvesicles carry distinct CEACAMs and influence T-cell behavior
    • PMID: 24040308
    • Muturi HT, Dreesen JD, Nilewski E, Jastrow H, Giebel B, Ergun S, et al. Tumor and endothelial cellderived microvesicles carry distinct CEACAMs and influence T-cell behavior. PloS one. 2013; 8(9): e74654. doi: 10.1371/journal.pone.0074654 PMID: 24040308
    • (2013) PloS One , vol.8 , Issue.9 , pp. e74654
    • Muturi, H.T.1    Dreesen, J.D.2    Nilewski, E.3    Jastrow, H.4    Giebel, B.5    Ergun, S.6
  • 37
    • 24144490843 scopus 로고    scopus 로고
    • CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells
    • PMID: 16115956
    • Muenzner P, Rohde M, Kneitz S, Hauck CR. CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol. 2005; 170 (5):825-36. PMID: 16115956
    • (2005) J Cell Biol , vol.170 , Issue.5 , pp. 825-836
    • Muenzner, P.1    Rohde, M.2    Kneitz, S.3    Hauck, C.R.4
  • 38
    • 33748310638 scopus 로고    scopus 로고
    • CEACAMs: Their role in physiology and pathophysiology
    • PMID: 16919437
    • Kuespert K, Pils S, Hauck CR. CEACAMs: their role in physiology and pathophysiology. Curr Opin Cell Biol. 2006; 18(5):565-71. PMID: 16919437
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.5 , pp. 565-571
    • Kuespert, K.1    Pils, S.2    Hauck, C.R.3
  • 39
    • 84875228644 scopus 로고    scopus 로고
    • Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting
    • PMID: 23322207
    • Tiernan JP, Perry SL, Verghese ET, West NP, Yeluri S, Jayne DG, et al. Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting. Br J Cancer. 2013; 108(3):662-7. doi: 10.1038/bjc.2012.605 PMID: 23322207
    • (2013) Br J Cancer , vol.108 , Issue.3 , pp. 662-667
    • Tiernan, J.P.1    Perry, S.L.2    Verghese, E.T.3    West, N.P.4    Yeluri, S.5    Jayne, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.