Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

Cell Reports

Volumn 15, Issue 6, 2016, Pages 1175-1189

  Lau, Eunice Yuen Ting ^a,b,e   Lo, Jessica ^a,b,e   Cheng, Bowie Yik Ling ^a,b   Ma, Mark Kin Fai ^a,b   Lee, Joyce Man Fong ^a,b   Ng, Johnson Kai Yu ^a,b   Chai, Stella ^a,b   Lin, Chi Ho ^c   Tsang, Suk Ying ^d   Ma, Stephanie ^a,b   Ng, Irene Oi Lin ^a,b   Lee, Terence Kin Wah ^a,b,e  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^e HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Cancer associated fibroblasts (CAFs); FRA1; Hepatocyte growth factor (HGF); HEY1; Tumor initiating cells (T ICs)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN HEY1; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FRA 1; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CELL CYCLE PROTEIN; CONDITIONED MEDIUM; HEY1 PROTEIN, HUMAN; MESSENGER RNA; PROTEIN C FOS; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER CELL; CANCER PROGNOSIS; CANCER STEM CELL; CELL PLASTICITY; CONTROLLED STUDY; DRUG TARGETING; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER FIBROSIS; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT; ANIMAL; CARCINOGENESIS; CELL SEPARATION; CONDITIONED MEDIUM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; PHARMACOLOGY; SCID MOUSE; TUMOR CELL LINE; UPREGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOMARKERS, TUMOR; CANCER-ASSOCIATED FIBROBLASTS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SEPARATION; CULTURE MEDIA, CONDITIONED; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE GROWTH FACTOR; HUMANS; LIVER NEOPLASMS; MICE, SCID; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-MET; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84964595266     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.04.019     Document Type: Article

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