Enterobacter cloacae inhibits human norovirus infectivity in gnotobiotic pigs

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Lei, Shaohua ^a   Samuel, Helen ^a   Twitchell, Erica ^a   Bui, Tammy ^a   Ramesh, Ashwin ^a   Wen, Ke ^a   Weiss, Mariah ^a   Li, Guohua ^a   Yang, Xingdong ^a   Jiang, Xi ^b   Yuan, Lijuan ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; B LYMPHOCYTE; BLOOD; CALICIVIRUS INFECTION; ENTEROBACTER CLOACAE; GASTROENTERITIS; GENETICS; GERMFREE ANIMAL; HUMAN; INTESTINE; MICROBIOLOGY; NOROVIRUS; PATHOGENICITY; PHYSIOLOGY; PIG; VIROLOGY; VIRUS GENOME; VIRUS LOAD; VIRUS SHEDDING;

ANIMALS; B-LYMPHOCYTES; BLOOD; CALICIVIRIDAE INFECTIONS; ENTEROBACTER CLOACAE; GASTROENTERITIS; GENOME, VIRAL; GERM-FREE LIFE; HUMANS; INTESTINES; NOROVIRUS; SUS SCROFA; SWINE; VIRAL LOAD; VIRUS SHEDDING;

EID: 84964594808     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep25017     Document Type: Article

References (42)

1. Ahmed, S. M. et al. Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis. Lancet Infect Dis 14, 725-30 (2014).
2. Karst, S. M. Pathogenesis of noroviruses, emerging RNA viruses. Viruses 2, 748-81 (2010).
3. Zheng, D. P. et al. Norovirus classification and proposed strain nomenclature. Virology 346, 312-23 (2006).
4. Kroneman, A. et al. Proposal for a unified norovirus nomenclature and genotyping. Arch Virol 158, 2059-68 (2013).
5. Bull, R. A., Eden, J. S., Rawlinson, W. D. & White, P. A. Rapid evolution of pandemic noroviruses of the GII.4 lineage. PLoS Pathog 6, e1000831 (2010).
6. White, P. A. Evolution of norovirus. Clin Microbiol Infect 20, 741-5 (2014).
7. Chan, M. C. et al. Rapid emergence and predominance of a broadly recognizing and fast-evolving norovirus GII.17 variant in late 2014. Nat Commun 6, 10061 (2015).
8. Wang, H. B. et al. Complete nucleotide sequence analysis of the norovirus GII.17: A newly emerging and dominant variant in China, 2015. Infect Genet Evol 38, 47-53 (2015).
9. Lee, C. C. et al. Emerging Norovirus GII.17 in Taiwan. Clin Infect Dis 61, 1762-4 (2015).
10. Kocher, J. & Yuan, L. Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives. Future Virol 10, 899-913 (2015).
11. Bok, K. et al. Chimpanzees as an animal model for human norovirus infection and vaccine development. Proc Natl Acad Sci USA 108, 325-30 (2011).
12. Souza, M., Azevedo, M. S., Jung, K., Cheetham, S. & Saif, L. J. Pathogenesis and immune responses in gnotobiotic calves after infection with the genogroup II.4-HS66 strain of human norovirus. J Virol 82, 1777-86 (2008).
13. Cheetham, S. et al. Pathogenesis of a genogroup II human norovirus in gnotobiotic pigs. J Virol 80, 10372-81 (2006).
14. Bui, T. et al. Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age. J Gen Virol 94, 2005-16 (2013).
15. Jung, K. et al. The effects of simvastatin or interferon-alpha on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals. PLoS One 7, e41619 (2012).
16. Taube, S. et al. A mouse model for human norovirus. MBio 4, e00450-13 (2013).
17. Miura, T. et al. Histo-blood group antigen-like substances of human enteric bacteria as specific adsorbents for human noroviruses. J Virol 87, 9441-51 (2013).
18. Jones, M. K. et al. Enteric bacteria promote human and mouse norovirus infection of B cells. Science 346, 755-9 (2014).
19. Jones, M. K. et al. Human norovirus culture in B cells. Nat Protoc 10, 1939-47 (2015).
20. Karst, S. M. & Wobus, C. E. A working model of how noroviruses infect the intestine. PLoS Pathog 11, e1004626 (2015).
21. Saif, L. J., Ward, L. A., Yuan, L., Rosen, B. I. & To, T. L. The gnotobiotic piglet as a model for studies of disease pathogenesis and immunity to human rotaviruses. Arch Virol Suppl 12, 153-61 (1996).
22. Yuan, L., Ward, L. A., Rosen, B. I., To, T. L. & Saif, L. J. Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. J Virol 70, 3075-83 (1996).
23. Kocher, J. et al. Intranasal P particle vaccine provided partial cross-variant protection against human GII.4 norovirus diarrhea in gnotobiotic pigs. J Virol 88, 9728-43 (2014).
24. Karst, S. M., Wobus, C. E., Goodfellow, I. G., Green, K. Y. & Virgin, H. W. Advances in norovirus biology. Cell Host Microbe 15, 668-80 (2014).
25. Zhang, W. et al. Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Vet Immunol Immunopathol 122, 175-81 (2008).
26. Wen, K. et al. Development of gammadelta T cell subset responses in gnotobiotic pigs infected with human rotaviruses and colonized with probiotic lactobacilli. Vet Immunol Immunopathol 141, 267-75 (2011).
27. Wen, K. et al. Lactobacillus rhamnosus GG Dosage Affects the Adjuvanticity and Protection Against Rotavirus Diarrhea in Gnotobiotic Pigs. J Pediatr Gastroenterol Nutr 60, 834-43 (2015).
28. Zhang, H. et al. Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs. Gut Pathog 6, 39 (2014).
29. Wen, K. et al. Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model. PLos One 9, e94504 (2014).
30. Takanashi, S. et al. Detection, genetic characterization, and quantification of norovirus RNA from sera of children with gastroenteritis. J Clin Virol 44, 161-3 (2009).
31. Fumian, T. M. et al. Quantitative and molecular analysis of noroviruses RNA in blood from children hospitalized for acute gastroenteritis in Belem, Brazil. J Clin Virol 58, 31-5 (2013).
32. Potockova, H., Sinkorova, J., Karova, K. & Sinkora, M. The distribution of lymphoid cells in the small intestine of germ-free and conventional piglets. Dev Comp Immunol 51, 99-107 (2015).
33. Wen, K. et al. High dose and low dose Lactobacillus acidophilus exerted differential immune modulating effects on T cell immune responses induced by an oral human rotavirus vaccine in gnotobiotic pigs. Vaccine 30, 1198-207 (2012).
34. Liu, F. et al. Dual functions of Lactobacillus acidophilus NCFM as protection against rotavirus diarrhea. J Pediatr Gastroenterol Nutr 58, 169-76 (2014).
35. Asanaka, M. et al. Replication and packaging of Norwalk virus RNA in cultured mammalian cells. Proc Natl Acad Sci USA 102, 10327-32 (2005).
36. Katayama, K. et al. Plasmid-based human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA. Proc Natl Acad Sci USA 111, E4043-52 (2014).
37. Papafragkou, E., Hewitt, J., Park, G. W., Greening, G. & Vinje, J. Challenges of culturing human norovirus in three-dimensional organoid intestinal cell culture models. PLos One 8, e63485 (2014).
38. Herbst-Kralovetz, M. M. et al. Lack of norovirus replication and histo-blood group antigen expression in 3-dimensional intestinal epithelial cells. Emerg Infect Dis 19, 431-8 (2013).
39. Rubio-del-Campo, A. et al. Noroviral p-particles as an in vitro model to assess the interactions of noroviruses with probiotics. PLos One 9, e89586 (2014).
40. Davin-Regli, A. & Pages, J. M. Enterobacter aerogenes and Enterobacter cloacae; versatile bacterial pathogens confronting antibiotic treatment. Front Microbiol 6, 392 (2015).
41. Bodey, G. P. Managing infections in the immunocompromised patient. Clin Infect Dis 40 Suppl 4, S239 (2005).
42. Meyer, R. C., Bohl, E. H. & Kohler, E. M. Procurement and Maintenance of Germ-Free Seine for Microbiological Investigations. Appl Microbiol 12, 295-300 (1964).