Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis

Cochrane Database of Systematic Reviews

Volumn 2016, Issue 4, 2016, Pages

  Head, Karen ^a   Chong, Lee Yee ^a   Hopkins, Claire ^b   Philpott, Carl ^c   Schilder, Anne G M ^d   Burton, Martin J ^a  

^a UK COCHRANE CENTRE   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; CORTISONE ACETATE; HYDROCORTISONE; METHYLPREDNISOLONE; NITRIC OXIDE; PREDNISOLONE; PREDNISONE; SODIUM CHLORIDE; STEROID;

AGITATION; ALLERGIC REACTION; ASSESSMENT OF HUMANS; BEHAVIOR DISORDER; BODY WEIGHT DISORDER; CHRONIC RHINOSINUSITIS; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; DELIRIUM; DISEASE SEVERITY; EDEMA; EUPHORIA; FACE PAIN; GASTROINTESTINAL SYMPTOM; HALITOSIS; HEADACHE; HUMAN; HYPERPIGMENTATION; HYPERTENSION; INCREASED APPETITE; INSOMNIA; LUND MACKAY SCORE; MOOD DISORDER; MOON FACE; MUSCLE WEAKNESS; NERVOUSNESS; NOSE OBSTRUCTION; NOSE POLYP; OSTEOPOROSIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PSYCHOSIS; PUBLISHING; QUALITY OF LIFE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SENSITIVITY ANALYSIS; SHORT COURSE THERAPY; SIDE EFFECT; SKIN ATROPHY; SKIN BRUISING; SYSTEMATIC REVIEW; VISUAL ANALOG SCALE; WEIGHT GAIN; ADJUVANT CHEMOTHERAPY; ADULT; CHILD; CHRONIC DISEASE; INTRANASAL DRUG ADMINISTRATION; META ANALYSIS; NASAL POLYPS; ORAL DRUG ADMINISTRATION; RHINITIS; SINUSITIS; TIME FACTOR;

ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; ADRENAL CORTEX HORMONES; ADULT; CHEMOTHERAPY, ADJUVANT; CHILD; CHRONIC DISEASE; HUMANS; METHYLPREDNISOLONE; NASAL POLYPS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RHINITIS; SINUSITIS; STEROIDS; TIME FACTORS;

EID: 84964460625     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD011992.pub2     Document Type: Review

References (84)

1. Bülbül T, Bülbül OG, Güçlü O, Bilsel AS, Gürsan SÖ. Effect of glucocorticoids on nasal polyposis, with detection of inflammatory response by measurement of nitric oxide levels in nasal polyp tissue. Journal of Laryngology and Otology 2013;27(6):584-9. [DOI: 10.1017/S002221511300073X]
2. Ozturk F, Bakirtas A, Ileri F, Turktas I. Efficacy and tolerability of systemic methylprednisolone in children and adolescents with chronic rhinosinusitis: a double-blind, placebo-controlled randomized trial. Journal of Allergy and Clinical Immunology 2011;128(2):348-52.
3. Alobid I, Benítez P, Bernal-Sprekelsen M, Roca J, Alonso J, Picado C, et al. Nasal polyposis and its impact on quality of life: comparison between the effects of medical and surgical treatments. Allergy 2005;60(4):452-8.
4. Alobid I, Benitez P, Pujols L, Maldonado M, Bernal-Sprekelsen M, Morello A, et al. Severe nasal polyposis and its impact on quality of life. The effect of a short course of oral steroids followed by long-term intranasal steroid treatment. Rhinology 2006;44(1):8-13.
5. Alobid I, Benitez P, Valero A, Munoz R, Langdon C, Mullol J. Oral and intranasal steroid treatments improve nasal patency and paradoxically increase nasal nitric oxide in patients with severe nasal polyposis. Rhinology 2012;2:171-7.
6. Alobid I, Benítez P, Cardelús S, de Borja Callejas F, Lehrer-Coriat E, Pujols L, et al. Oral plus nasal corticosteroids improve smell, nasal congestion, and inflammation in sino-nasal polyposis. Laryngoscope 2014;124(1):50-6.
7. Benitez P, Alobid I, Haro J, Berenguer J, Bernal-Sprekelsen, Pujols L, et al. A short course of oral prednisone followed by intranasal budesonide is an effective treatment of severe nasal polyps. Laryngoscope 2006;116(5):770-5.
8. Blomqvist EH, Lundblad L, Anggard A, Haraldsson P-O, Stjarne P. A randomized controlled study evaluating medical treatment versus surgical treatment in addition to medical treatment of nasal polyposis. Journal of Allergy and Clinical Immunology 2001;107(2):224-8.
9. Blomqvist EH, Lundblad L, Bergstedt H, Stjarne P. A randomized prospective study comparing medical and medical-surgical treatment of nasal polyposis by CT. Acta Oto-Laryngologica 2009;129(5):545-9.
10. Bonfils P. Medical treatment of paranasal sinus polyposis: a prospective study in 181 patients [Le traitement medical de la polypose naso-sinusienne: etude prospective sur une serie de 181 patients]. Annales d'Oto-Laryngologie et de Chirurgie Cervico Faciale 1998;115(4):202-14.
11. Bonfils P, Nores J-M, Halimi P, Avan P. Medical treatment of stage I nasal polyposis over a 3-year follow-up period. ORL; Journal of Oto-Rhino-Laryngology and Its Related Specialties 2004;66(1):27-34.
12. Bonfils P, Halimi P, Malinvaud D. Adrenal suppression and osteoporosis after treatment of nasal polyposis. Acta Oto-Laryngologica 2006;126(11):1195-200.
13. ChiCTR-TRC-11001323 . Research on clinical efficacy of oral glucocorticoid in the treatment of eosinophilic nasal polyps and non-eosinophilic nasal polyps. http://www.chictr.org.cn/showprojen.aspx?proj=8216. [ChiCTR-TRC-11001323]
14. Chi Chan A, Couto y Arcos F, Martin Biasotti F, Bross Soriano D, Vazquez Valle MDC, Gonzalez Olvera S. Oral steroids as preoperative medication in nasal polyposis [Esteroides orales en la preparacion preoperatoria de poliposis nasal]. Anales de Otorrinolaringologia Mexicana 1996;41(3):155-60.
15. Damm M, Jungehulsing M, Eckel HE, Schmidt M, Theissen P. Effects of systemic steroid treatment in chronic polypoid rhinosinusitis evaluated with magnetic resonance imaging. Otolaryngology - Head and Neck Surgery 1999;120(4):517-23.
16. Ecevit MC, Erdag TK, Dogan E, Sutay S. Effect of steroids for nasal polyposis surgery: a placebo-controlled, randomized, double-blind study. Laryngoscope 2015;125(9):2041-5. [DOI: 10.1002/lary.25352]
17. Grammer LC. Doxycycline or oral corticosteroids for nasal polyps. Journal of Allergy and Clinical Immunology: In Practice 2013;1(5):541-2.
18. Hessler JL, Piccirillo JF, Fang D, Vlahiotis A, Banerji A, Levitt RG, et al. Clinical outcomes of chronic rhinosinusitis in response to medical therapy: results of a prospective study. American Journal of Rhinology 2007;21(1):10-8.
19. Hissaria P, Smith W, Wormald PJ, Taylor J, Vadas M, Gillis D, et al. Short course of systemic corticosteroids in sinonasal polyposis: a double-blind, randomized, placebo-controlled trial with evaluation of outcome measures. Journal of Allergy and Clinical Immunology 2006;118(1):128-33.
20. Jankowski R, Bodino C. Evolution of symptoms associated to nasal polyposis following oral steroid treatment and nasalisation of the ethmoid - radical ethmoidectomy is functional surgery for NPS. Rhinology 2003;41(4):211-9.
21. Jankowski R, Bodino C. Olfaction in patients with nasal polyposis: effects of systemic steroids and radical ethmoidectomy with middle turbinate resection (nasalisation). Rhinology 2003;41(4):220-30.
22. Kapucu B, Cekin E, Erkul BE, Cincik H, Gungor A, Berber U. The effects of systemic, topical, and intralesional steroid treatments on apoptosis level of nasal polyps. Otolaryngology - Head and Neck Surgery 2012;147(3):563-7. [DOI: 10.1177/0194599812446678]
23. Kirtsreesakul V, Wongsritrang K, Ruttanaphol S. Clinical efficacy of a short course of systemic steroids in nasal polyposis. Rhinology 2011;49(5):525-32.
24. Kirtsreesakul V, Wongsritrang K, Ruttanaphol S. Does oral prednisolone increase the efficacy of subsequent nasal steroids in treating nasal polyposis?. American Journal of Rhinology & Allergy 2012;26(6):455-62.
25. Kroflic B, Baudoin T, Kalogjera L. Topical furosemide versus oral steroid in preoperative management of nasal polyposis. European Archives of Oto-Rhino-Laryngology 2006;263(8):767-71.
26. Lildholdt T, Fogstrup J, Gammelgaard N, Kortholm B, Ulsoe C. Surgical versus medical treatment of nasal polyps. Acta Oto-Laryngologica 1988;105(1-2):140-3.
27. Lildholdt T. Surgical versus medical treatment of nasal polyps. Rhinology. Supplement 1989;8:31-3.
28. Martínez-Antón A, de Bolós C, Alobid I, Benítez P, Roca-Ferrer J, Picado C, et al. Corticosteroid therapy increases membrane-tethered while decreases secreted mucin expression in nasal polyps. Allergy: European Journal of Allergy and Clinical Immunology 2008;63(10):1368-76.
29. Chronic rhinosinusitis with or without nasal polyps steroid study. http://clinicaltrials.gov/ct2/show/NCT00841802. [NCT00841802]
30. Prednisone in chronic rhinosinusitis without nasal polyps. http://clinicaltrials.gov/ct2/show/NCT02367118.
31. Nores J-M, Avan P, Bonfils P. Medical management of nasal polyposis: a study in a series of 152 consecutive patients. Rhinology 2003;41(2):97-102.
32. Ragab S, Scadding GK, Lund VJ, Saleh H. Treatment of chronic rhinosinusitis and its effects on asthma. European Respiratory Journal 2006;28(1):68-74.
33. Rasp G, Bujia J. Treatment of nasal polyposis with systemic and local corticoids. Acta Otorrinolaringologica Espanola 1997;48(1):37-40.
34. Rasp G, Kramer MF, Ostertag P, Kastenbauer E. A new system for the classification of ethmoid polyposis. Effect of combined local and systemic steroid therapy. Laryngo-Rhino-Otologie 2000;79(5):266-72.
35. Remer M, Polberg K, Obszańska B, Klatka J. Chronic sinusitis therapy with antibiotics (axetyl cefuroxym, clarithromycin) and steroid (prednisone) [Leczenie zapalenia zatok z zastosowaniem antybiotykow (aksetyl cefuroksymu, klarytromycyna) w polaczeniu ze sterydem stosowanym doustnie (prednison)]. Polski Merkuriusz Lekarski 2005;19(111):343-4.
36. Reychler G, Colbrant C, Huart C, Le Guellec S, Vecellio L, Liistro G, et al. Effect of three-drug delivery modalities on olfactory function in chronic sinusitis. Laryngoscope 2015;125(3):549-55.
37. Rupa V, Jacob M, Mathews MS, Seshadri MS. A prospective, randomised, placebo-controlled trial of postoperative oral steroid in allergic fungal sinusitis. European Archives of Oto-rhino-laryngology 2010;267(2):233-8. [DOI: 10.1007/s00405-009-1075-8]
38. Sieskiewicz A, Olszewska E, Rogowski M, Grycz E. Preoperative corticosteroid oral therapy and intraoperative bleeding during functional endoscopic sinus surgery in patients with severe nasal polyposis: a preliminary investigation. Annals of Otology, Rhinology and Laryngology 2006;115(7):490-4.
39. Sousa MC, Becker HM, Becker CG, Castro MM, Sousa NJ, Guimarães RE. Reproducibility of the three-dimensional endoscopic staging system for nasal polyposis. Brazilian Journal of Otorhinolaryngology 2009;75(6):814-20.
40. Stevens MH. Steroid-dependent anosmia. Laryngoscope 2001;111(2):200-3.
41. Tuncer U, Soylu L, Aydogan B, Karakus F, Akcali C. The effectiveness of steroid treatment in nasal polyposis. Auris Nasus Larynx 2003;30(3):263-8.
42. Vaidyanathan S, Barnes M, Williamson P, Hopkinson P, Donnan PT, Lipworth B. Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial. Annals of Internal Medicine 2011;154:293-302.
43. van Camp C, Clement PA. Results of oral steroid treatment in nasal polyposis. Rhinology 1994;32(1):5-9.
44. Van Zele T, Gevaert P, Holtappels G. Treatment of nasal polyposis with oral methylprednisolone: a double-blind, randomized, placebo-controlled trial with evaluation of clinical and biological activity. Journal of Allergy and Clinical Immunology 2008;121(2 Suppl 1):S265.
45. Van Zele T, Gevaert P, Holtappels G, Beule A, Wormald PJ, Mayr S, et al. Oral steroids and doxycycline: two different approaches to treat nasal polyps. Journal of Allergy and Clinical Immunology 2010;125(5):1069-76.e4.
46. Northwestern University Feinberg School of Medicine. Corticosteroid therapy for chronic rhinosinusitis without nasal polyps (CRSsNP). http://clinicaltrials.gov/ct2/show/NCT01676415. [NCT01676415]
47. Balk EM, Earley A, Patel K, Trikalinos TA, Dahabreh IJ. Empirical assessment of within-arm correlation imputation in trials of continuous outcomes [Internet]. Report No.: 12(13)-EHC141-EF. AHRQ Methods for Effective Health Care. Rockville (MD): Agency for Healthcare Research and Quality, 2012.
48. Burton MJ, Harvey RJ. Idiopathic sudden sensorineural hearing loss. In: Gleeson M, Browning G, Burton MJ, Clarke R, Hibbert J, Jones NS, et al. editor(s). Scott-Brown's Otorhinolaryngology, Head and Neck Surgery. 7th Edition. Vol. 3, London: Hodder Arnold, 2008:3577-93.
49. Cho SH, Hong SJ, Han B, Lee SH, Suh L, Norton J, et al. Age-related differences in the pathogenesis of chronic rhinosinusitis. Journal of Allergy and Clinical Immunology 2012;129(3):858-60.e2.
50. Chong LY, Head K, Hopkins C, Philpott C, Schilder AGM, Burton MJ. Different types of intranasal steroids for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2016, Issue 4. [DOI: 10.1002/14651858.CD011993.pub2]
51. Chong LY, Head K, Hopkins C, Philpott C, Schilder AGM, Burton MJ. Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2016, Issue 4. [DOI: 10.1002/14651858.CD011996.pub2]
52. Chong LY, Head K, Hopkins C, Philpott C, Glew S, Scadding G, et al. Saline irrigation for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2016, Issue 4. [DOI: 10.1002/14651858.CD011995.pub2]
53. Cohen J. Statistical Power Analysis in the Behavioral Sciences. 2nd Edition. Hillsdale (NJ): Lawrence Erlbaum Associates, Inc., 1988.
54. Côté DWJ, Wright ED. Objective Outcomes in Endoscopic Sinus Surgery, Advances in Endoscopic Surgery. InTech, 2011.
55. Da Silva JA, Jacobs JW, Kirwan JR, Boers M, Saag KG, Inês LB, et al. Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data. Annals of the Rheumatic Diseases 2006;65:285-93.
56. DeMarcantonio MA, Han JK. Nasal polyps: pathogenesis and treatment implications. Otolaryngologic Clinics of North America 2011;44(3):685-95, ix.
57. Ebbens FA, Toppila-Salmi SK, Renkonen JA, Renkonen RL, Mullol J, van Drunen CM, et al. Endothelial L-selectin ligand expression in nasal polyps. Allergy 2010;65(1):95-102.
58. Ebbens FA, Toppila-Salmi S, de Groot EJ, Renkonen J, Renkonen R, van Drunen CM, et al. Predictors of post-operative response to treatment: a double blind placebo controlled study in chronic rhinosinusitis patients. Rhinology 2011;49(4):413-9.
59. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ (Clinical research ed.) 1997;315(7109):629-34. [PUBMED: 9310563]
60. Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinology. Supplement 2012;50 Suppl 23:1-298.
61. Fokkens W, Lund V, Mullol J. European position paper on rhinosinusitis and nasal polyps 2007. Rhinology 45;Suppl 20:1-139.
62. Gliklich RE, Metson R. The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngology - Head and Neck Surgery 1995;113(1):104-9.
63. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
64. 2LEN study. Allergy 2011;66(9):1216-23.
65. Head K, Chong LY, Hopkins C, Philpott C, Burton MJ, Schilder AGM. Short-course oral steroids alone for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2016, Issue 4. [DOI: 10.1002/14651858.CD011991.pub2]
66. Head K, Chong LY, Piromchai P, Hopkins C, Philpott C, Schilder AGM, et al. Systemic and topical antibiotics for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2016, Issue 4. [DOI: 10.1002/14651858.CD011994.pub2]
67. Kern RC, Conley DB, Walsh W, Chandra R, Kato A, Tripathi-Peters A, et al. Perspectives on the etiology of chronic rhinosinusitis: an immune barrier hypothesis. American Journal of Rhinology 2008;22(6):549-59.
68. Keswani A, Chustz RT, Suh L, Carter R, Peters AT, Tan BK, et al. Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps. Allergy 2012;67(1):25-32.
69. Larsen P, Tos M. Origin of nasal polyps: an endoscopic autopsy study. Laryngoscope 2004;114(4):710-9.
70. Martinez-Devesa P, Patiar S. Oral steroids for nasal polyps. Cochrane Database of Systematic Reviews 2011, Issue 7. [DOI: 10.1002/14651858.CD005232.pub3]
71. Mygind N, Lildholdt T. Nasal polyps treatment: medical management. Allergy and Asthma Proceedings 1996;17:275-82.
72. Naber D, Sand P, Heigl B. Psychopathological and neuropsychological effects of 8-days' corticosteroid treatment. A prospective study. Psychoneuroendocrinology 1996;21:25-31.
73. Ragab SM, Lund VJ, Scadding G. Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial. Laryngoscope 2004;114(5):923-30.
74. Ragab SM, Lund VJ, Scadding G, Saleh HA, Khalifa MA. Impact of chronic rhinosinusitis therapy on quality of life: a prospective randomized controlled trial. Rhinology 2010;48(3):305-11.
75. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
76. Stanbury RM, Graham EM. Systemic corticosteroid therapy--side effects and their management. British Journal of Ophthalmology 1998;82:704-8.
77. Tan BK, Li QZ, Suh L, Kato A, Conley DB, Chandra RK, et al. Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology 2011;128(6):1198-206.e1.
78. Tomassen P, Van Zele T, Zhang N, Perez-Novo C, Van Bruaene N, Gevaert P, et al. Pathophysiology of chronic rhinosinusitis. Proceedings of the American Thoracic Society 2011;8(1):115-20.
79. van Drunen CM, Reinartz SM, Wigman J, Fokkens W. Inflammation in chronic rhinosinusitis and nasal polyposis. Immunology and Allergy Clinics of North America 2009;29(4):621-9.
80. Venekamp RP, Thompson MJ, Hayward G, Heneghan CJ, Del Mar CB, Perera R, et al. Systemic corticosteroids for acute sinusitis. Cochrane Database of Systematic Reviews 2014, Issue 3. [DOI: 10.1002/14651858.CD008115.pub3]
81. Venekamp RP, Thompson MJ, Rovers MM. Systemic corticosteroid therapy for acute sinusitis. JAMA 2015;313(12):1258-9.
82. Zhang N, Van Zele T, Perez-Novo C, Van Bruaene N, Holtappels G, DeRuyck N, et al. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. Journal of Allergy and Clinical Immunology 2008;122(5):961-8.
83. Zhang XH, Lu X, Long XB, You XJ, Gao QX, Cui YH, et al. Chronic rhinosinusitis with and without nasal polyps is associated with decreased expression of glucocorticoid-induced leucine zipper. Clinical and Experimental Allergy 2009;39(5):647-54.
84. Chong LY, Head K, Hopkins C, Philpott C, Burton MJ. Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis. Cochrane Database of Systematic Reviews 2015, Issue 12. [DOI: 10.1002/14651858.CD011992]