Cadaveric cardiosphere-derived cells can maintain regenerative capacity and improve the heart function of cardiomyopathy

Cell Cycle

Volumn 15, Issue 9, 2016, Pages 1248-1256

  Sun, Yong ^a,b   Chi, Di ^a,b   Tan, Miaoxin ^c   Kang, Kai ^b   Zhang, Maomao ^a,b   Jin, Xiangyuan ^a   Leng, Xiaoping ^b   Cao, Rui ^a,b   Liu, Xianglan ^b   Yu, Bo ^a,b   Wu, Jian ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c First Hospital of Fangshan District   (China)

Author keywords

allograft transplantation; cadaver; cardiosphere derived cells; dilated cardiomyopathy

Indexed keywords

DOXORUBICIN; GROWTH FACTOR; VON WILLEBRAND FACTOR; HOMEOBOX PROTEIN NKX-2.5; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR GATA 4;

ADOLESCENT; ADULT; AGED; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CADAVER; CARDIAC MUSCLE CELL; CARDIOMYOPATHY; CARDIOSPHERE DERIVED CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CHILD; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE SIZE; HEART VENTRICLE REMODELING; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NONISCHEMIC CARDIOMYOPATHY; PARACRINE SIGNALING; PROTEIN EXPRESSION; TISSUE REGENERATION; ANIMAL; C57BL MOUSE; CELL SURVIVAL; CYTOLOGY; HEART; METABOLISM; MIDDLE AGED; MULTICELLULAR SPHEROID; PATHOPHYSIOLOGY; PRESCHOOL CHILD; REGENERATION; STEM CELL; STEM CELL TRANSPLANTATION; TIME FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; CADAVER; CARDIOMYOPATHIES; CELL DIFFERENTIATION; CELL SURVIVAL; CHILD; CHILD, PRESCHOOL; GATA4 TRANSCRIPTION FACTOR; HEART; HOMEOBOX PROTEIN NKX-2.5; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE, INBRED C57BL; MIDDLE AGED; MYOCYTES, CARDIAC; REGENERATION; SPHEROIDS, CELLULAR; STEM CELL TRANSPLANTATION; STEM CELLS; TIME FACTORS; YOUNG ADULT;

EID: 84964446490     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2016.1160973     Document Type: Article

References (30)

1. V.Sousonis, J.Nanas, J.Terrovitis. Cardiosphere-derived progenitor cells for myocardial repair following myocardial infarction. Curr Pharm Des 2014; 20:2003-11; PMID:23844734; http://dx.doi.org/10.2174/13816128113199990445
2. S.Valente, F.Alviano, C.Ciavarella, M.Buzzi, F.Ricci, P.L.Tazzari, P.Pagliaro, G.Pasquinelli. Human cadaver multipotent stromal/stem cells isolated from arteries stored in liquid nitrogen for 5 years. Stem Cell Res Ther 2014; 5:8-10; PMID:24429026; http://dx.doi.org/10.1186/scrt397
3. S.Valente, F.Alviano, C.Ciavarella, M.Buzzi, F.Ricci, P.L.Tazzari, P.Pagliaro, G.Pasquinelli. Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity. Nat Commun 2012; 3:903; PMID:22692546; http://dx.doi.org/10.1038/ncomms1890
4. L.Erker, H.Azuma, A.Y.Lee, C.Guo, S.Orloff, L.Eaton, E.Benedetti, B.Jensen, M.Finegold, H.Willenbring, et al. Therapeutic liver reconstitution with murine cells isolated long after death. Gastroenterology 2010; 139:1019-29; PMID:20621682; http://dx.doi.org/10.1053/j.gastro.2010.05.082
5. L.Erker, H.Azuma, A.Y.Lee, C.Guo, S.Orloff, L.Eaton, E.Benedetti, B.Jensen, M.Finegold, H.Willenbring, M.Grompe. et al. Isolation and expansion of adult cardiac stem cells from human and murine heart.Circ Res 2004; 95:911-21; PMID:15472116; http://dx.doi.org/10.1161/01.RES.0000147315.71699.51
6. M.Kreke, R.R.Smith, L.Marbán, E.Marbán. Cardiospheres and cardiosphere-derived cells as therapeutic agents following myocardial infarction. Expert Rev Cardiovasc Ther 2012; 10:1185-94; PMID:23098154; http://dx.doi.org/10.1586/erc.12.102
7. Y.L.Tang, Y.J.Wang, L.J.Chen, Y.H.Pan, L.Zhang, N.L.Weintraub. Cardiac-derived stem cell-based therapy for heart failure: progress and clinical applications. Exp Biol Med (Maywood) 2013; 238:294-300; PMID:23598975; http://dx.doi.org/10.1177/1535370213477982
8. P.V.Johnston, T.Sasano, K.Mills, R.Evers, S.T.Lee, R.R.Smith, A.C.Lardo, S.Lai, C.Steenbergen, G.Gerstenblith, et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009; 120:1075-83; PMID:19738142; http://dx.doi.org/10.1161/CIRCULATIONAHA.108.816058
9. T.S.Li, K.Cheng, K.Malliaras, R.R.Smith, Y.Zhang, B.Sun, N.Matsushita, A.Blusztajn, J.Terrovitis, H.Kusuoka, et al. Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 2012; 59:942-53; PMID:22381431; http://dx.doi.org/10.1016/j.jacc.2011.11.029
10. E.Tseliou, S.Pollan, K.Malliaras, J.Terrovitis, B.Sun, G.Galang, L.Marbán, D.Luthringer, E.Marbán. Allogeneic cardiospheres safely boost cardiac function and attenuate adverse remodeling after myocardial infarction in immunologically mismatched rat strains. J Am Coll Cardiol 2013; 61:1108-19; PMID:23352785; http://dx.doi.org/10.1016/j.jacc.2012.10.052
11. K.Malliaras, T.S.Li, D.Luthringer, J.Terrovitis, K.Cheng, T.Chakravarty, G.Galang, Y.Zhang, F.Schoenhoff, J.Van Eyk, et al. Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells. Circulation 2012; 125:100-12; PMID:22086878; http://dx.doi.org/10.1161/CIRCULATIONAHA.111.042598
12. R.R.Makkar, R.R.Smith, K.Cheng, K.Malliaras, L.E.Thomson, D.Berman, L.S.Czer, L.Marbán, A.Mendizabal, P.V.Johnston, et al. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 2012; 379:895-904; PMID:22336189; http://dx.doi.org/10.1016/S0140-6736(12)60195-0
13. M.A.Aminzadeh, E.Tseliou, B.Sun, K.Cheng, K.Malliaras, R.R.Makkar, E.Marbán. Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy. Eur Heart J 2014; 36:751-62; PMID:24866210; http://dx.doi.org/10.1093/eurheartj/ehu196
14. R.R.Smith, L.Barile, H.C.Cho, M.K.Leppo, J.M.Hare, E.Messina, A.Giacomello, M.R.Abraham, E.Marbán. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 2007; 115:896-908; 17283259; http://dx.doi.org/10.1161/CIRCULATIONAHA.106.655209
15. E.Mansilla, K.Mártire, G.Roque, J.M.Tau, G.H.Marín, M.V.Castuma, G.Orlandi, A.Tarditti. Salvage of Cadaver Stem Cells (CSCs) as a Routine Procedure: History or Future for Regenerative Medicine. J Transplant Technol Res 2013; 3:118
16. W.Marlicz, M.Paczkowski, J.Kijowski, B.Machalinski. Isolation of hematopoietic stem cells from heparinized cadaveric multiple organ donors: potential clinical implications. Transplant Proc 1999; 31:2099-2101; PMID:10455982; http://dx.doi.org/10.1016/S0041-1345(99)00275-4
17. J.Michalova, F.Savvulidi, L.Sefc, K.Forgacova, E.Necas. Cadaveric bone marrow as potential source of hematopoietic stem cells for transplantation. Chimerism 2011; 2:86-87; PMID:22163067; http://dx.doi.org/10.4161/chim.17917
18. C.Raffoux. Collaboration between hematopoietic stem cell donor registry and cord blood banks.Transplant Proc 2010; 42:3258-3259; PMID:20970667; http://dx.doi.org/10.1016/j.transproceed.2010.07.032
19. J.Michalova, F.Savvulidi, L.Sefc, K.Faltusova, K.Forgacova, E.Necas. Hematopoietic stem cells survive circulation arrest and reconstitute hematopoiesis in myeloablated mice. Biol Blood Marrow Transplant 2011; 17:1273-81; PMID:21767513; http://dx.doi.org/10.1016/j.bbmt.2011.07.007
20. B.Machaliński, M.Paczkowski, M.Kawa, E.Paczkowska, M.Ostrowski. An optimization of isolation of early hematopoietic cells from heparinized cadaveric organ donors. Transplant Proc 2003; 35:3096-3100; PMID:14697988; http://dx.doi.org/10.1016/j.transproceed.2003.10.082
21. X.Liu, Y.Zhu, W.Gao. Isolation of neural stem cells from the spinal cords of low temperature preserved abortuses. J Neurosci Methods 2006; 157:64-70; PMID:16682082; http://dx.doi.org/10.1016/j.jneumeth.2006.03.025
22. A.D.Donnenberg, V.S.Gorantla, S.Schneeberger, L.R.Moore, G.Brandacher, H.M.Stanczak, E.K.Koch, W.A.Lee. Clinical implementation of a procedure to prepare bone marrow cells from cadaveric vertebral bodies. Regen Med 2011; 6:701-706; PMID:22050522; http://dx.doi.org/10.2217/rme.11.89
23. V.S.Gorantla, S.Schneeberger, L.R.Moore, V.S.Donnenberg, L.Zimmerlin, W.P.Lee, A.D.Donnenberg Development and validation of a procedure to isolate viable bone marrow cells from the vertebrae of cadaveric organ donors for composite organ grafting. Cytotherapy 2012; 14:104-113; PMID:21905958; http://dx.doi.org/10.3109/14653249.2011.605350
24. B.E.Hjelm, J.B.Rosenberg, S.Szelinger, L.I.Sue, T.G.Beach, M.J.Huentelman, D.W.Craig. Induction of pluripotent stem cells from autopsy donor-derived somatic cells. Neurosci Lett 2011; 502:219-224; PMID:21839145; http://dx.doi.org/10.1016/j.neulet.2011.07.048
25. A.G.Ibrahim, K.Cheng, E.Marbán. Exosomes as critical agents of cardiac regeneration triggered by cell therapy. Stem Cell Reports 2014; 2:606-19; PMID:24936449; http://dx.doi.org/10.1016/j.stemcr.2014.04.006
26. M.Perán, E.López-Ruiz, L.González-Herrera, M.Bustamante, A.Valenzuela, J.A.Marchal. Cellular extracts from post-mortem human cardiac tissue direct cardiomyogenic differentiation of human adipose tissue-derived stem cells. Cytotherapy 2013; 15:1541-8; http://dx.doi.org/10.1016/j.jcyt.2013.06.016
27. Y.L.Tang, W.Zhu, M.Cheng, L.Chen, J.Zhang, T.Sun, R.Kishore, M.I.Phillips, D.W.Losordo, G.Qin. Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Circ Res 2009; 104:1209-16; PMID:19407239; http://dx.doi.org/10.1161/CIRCRESAHA.109.197723
28. A.T.Askari, S.Unzek, Z.B.Popovic, C.K.Goldman, F.Forudi, M.Kiedrowski, A.Rovner, S.G.Ellis, J.D.Thomas, P.E.DiCorleto, et al. Effect of stromal-cell-derived factor 1 on stemcell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 2003; 362:697-703; PMID:12957092; http://dx.doi.org/10.1016/S0140-6736(03)14232-8
29. K.Cheng, K.Malliaras, R.R.Smith, D.Shen, B.Sun, A.Blusztajn, Y.Xie, A.Ibrahim, M.A.Aminzadeh, W.Liu, et al. Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair. JACC Heart Fail 2014; 2:49-61; PMID:24511463; http://dx.doi.org/10.1016/j.jchf.2013.08.008
30. Y.Xie, A.Ibrahim, K.Cheng, Z.Wu, W.Liang, K.Malliaras, B.Sun, W.Liu, D.Shen, H.Cheol Cho, et al. Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. Stem Cells 2014; 32:2397-406; PMID:24802280; http://dx.doi.org/10.1002/stem.1736