Distinct endothelial cell responses in the heart and kidney microvasculature characterize the progression of heart failure with preserved ejection fraction in the obese ZSF1 rat with cardiorenal metabolic syndrome

Circulation: Heart Failure

Volumn 9, Issue 4, 2016, Pages

  Van Dijk, Christian G M ^a   Oosterhuis, Nynke R ^a   Xu, Yan Juan ^a   Brandt, Maarten ^c   Paulus, Walter J ^b   Van Heerebeek, Loek ^b   Duncker, Dirk J ^c   Verhaar, Marianne C ^a   Fontoura, Dulce ^d   Lourenço, André P ^d,e   Leite Moreira, Adelino F ^d,e   Falcão Pires, Inês ^d   Joles, Jaap A ^a   Cheng, Caroline ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF PORTO   (Portugal)

^e HOSPITAL DE SÃO JOÃO   (Portugal)

Author keywords

animal model; cardiorenal syndrome; endothelial cell; heart failure; mortality

Indexed keywords

ANGIOTENSIN 1 RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BODY WEIGHT; CARDIORENAL METABOLIC SYNDROME; CARDIORENAL SYNDROME; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DISEASE COURSE; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; ERYTHROCYTE; FIBROSIS; FUNCTIONAL DISEASE; GLOMERULOSCLEROSIS; HEART BLOOD VESSEL; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HEART LEFT VENTRICLE HYPERTROPHY; INFLAMMATION; KIDNEY BLOOD VESSEL; MALE; METABOLIC SYNDROME X; MICROVASCULATURE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT; URINALYSIS; ANIMAL; CARDIO-RENAL SYNDROME; COMPLICATION; CORONARY BLOOD VESSEL; DISEASE MODEL; GLOMERULONEPHRITIS; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEART VENTRICLE REMODELING; HYPERTROPHY, LEFT VENTRICULAR; KIDNEY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIME FACTOR; VASCULAR REMODELING; VASCULARIZATION; WISTAR KYOTO RAT; ZUCKER RAT;

ANIMALS; CARDIO-RENAL SYNDROME; CELL PROLIFERATION; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOTHELIAL CELLS; FIBROSIS; GLOMERULONEPHRITIS; HEART FAILURE; HYPERTROPHY, LEFT VENTRICULAR; KIDNEY; MALE; METABOLIC SYNDROME X; MICROVESSELS; PROTEINURIA; RATS, INBRED WKY; RATS, ZUCKER; STROKE VOLUME; TIME FACTORS; VASCULAR REMODELING; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84964413063     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.115.002760     Document Type: Article

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