Wide bandwidth nanomechanical assessment of murine cartilage reveals protection of aggrecan knock-in mice from joint-overuse

Journal of Biomechanics

Volumn 49, Issue 9, 2016, Pages 1634-1640

  Azadi, Mojtaba ^a,b   Nia, Hadi Tavakoli ^c   Gauci, Stephanie J ^d   Ortiz, Christine ^b   Fosang, Amanda J ^d   Grodzinsky, Alan J ^b,e  

^a SAN FRANCISCO STATE UNIVERSITY   (United States)

^b Massachusetts Institute of Technology   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e Department of Electrical Engineering and Computer Science   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ATOMIC FORCE MICROSCOPY; BANDWIDTH; CARTILAGE; GLYCOPROTEINS; MAMMALS; STIFFNESS; TISSUE;

CARTILAGE PATHOLOGY; FLUID SOLID INTERACTION; FORCE DISPLACEMENT; HYDRAULIC PERMEABILITY; POROELASTIC BEHAVIOR; QUASI EQUILIBRIUM; STIFFNESS MAGNITUDE; WILD-TYPE CONTROLS;

JOINTS (ANATOMY);

AGGRECAN; AGGRECANASE; PROTEINASE;

AGING; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOMECHANICS; CARTILAGE; CARTILAGE DEGENERATION; CONTROLLED STUDY; DISTAL FEMUR CARTILAGE; DNA MODIFICATION; DYNAMICS; ELASTIC CARTILAGE; FEMUR; FLUID SOLID INTERACTION; HISTOLOGY; HYDRAULIC PERMEABILITY; JOINT; JOINT OVERUSE; LOSS OF FUNCTION MUTATION; MICROMECHANICS; MICROSCALE; MOUSE; NANODYNAMIC; NANOELECTROMECHANICAL SYSTEM; NANOSCALE; NONHUMAN; PRIORITY JOURNAL; QUASI EQUILIBRIUM STRUCTURAL ELASTIC CARTILAGE; RIGIDITY; RUNNING; STATISTICAL SIGNIFICANCE; WIDE BANDWIDTH NANOMECHANICAL ASSESSMENT; ANIMAL; BOVINE; GENE TARGETING; GENETICS; HUMAN; MECHANICS; METABOLISM; NANOTECHNOLOGY; OSTEOARTHRITIS; PERMEABILITY;

AGGRECANS; AGING; ANIMALS; BIOMECHANICAL PHENOMENA; CARTILAGE; CATTLE; ENDOPEPTIDASES; FEMUR; GENE KNOCK-IN TECHNIQUES; HUMANS; MECHANICAL PHENOMENA; MICE; MICROSCOPY, ATOMIC FORCE; NANOTECHNOLOGY; OSTEOARTHRITIS; PERMEABILITY;

EID: 84964389424     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2016.03.055     Document Type: Article

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