-
1
-
-
84964335825
-
AAV Insertions in hepatocellular carcinoma do not inform debate over genotoxicity risk of vectorized AAV
-
Nault, J-C, Mami, I, La Bella, T, Datta, S, Imbeaud, S, Franconi, A, et al. (2016). AAV Insertions in hepatocellular carcinoma do not inform debate over genotoxicity risk of vectorized AAV. Mol Ther 24: 660-661
-
(2016)
Mol Ther
, vol.24
, pp. 660-661
-
-
Nault, J.-C.1
Mami, I.2
La Bella, T.3
Datta, S.4
Imbeaud, S.5
Franconi, A.6
-
2
-
-
84948649974
-
Adeno-Associated vector toxicity-To be or not to be?
-
Büning, H, and Schmidt, M. (2015). Adeno-Associated vector toxicity-To be or not to be?. Mol Ther 23: 1673-1675
-
(2015)
Mol Ther
, vol.23
, pp. 1673-1675
-
-
Büning, H.1
Schmidt, M.2
-
3
-
-
84942905508
-
Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
-
Nault, J-C, Datta, S, Imbeaud, S, Franconi, A, Mallet, M, Couchy, G, et al. (2015). Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas. Nat Genet 47: 1187-1193
-
(2015)
Nat Genet
, vol.47
, pp. 1187-1193
-
-
Nault, J.-C.1
Datta, S.2
Imbeaud, S.3
Franconi, A.4
Mallet, M.5
Couchy, G.6
-
4
-
-
84881436148
-
High frequency of telomerase reverse-Transcriptase promoter somatic mutations in hepatocellular carcinoma, and preneoplastic lesions
-
Nault, JC, Mallet, M, Pilati, C, Calderaro, J, Bioulac-Sage, P, Laurent, C, et al. (2013). High frequency of telomerase reverse-Transcriptase promoter somatic mutations in hepatocellular carcinoma, and preneoplastic lesions. Nat Commun 4: 2218
-
(2013)
Nat Commun
, vol.4
, pp. 2218
-
-
Nault, J.C.1
Mallet, M.2
Pilati, C.3
Calderaro, J.4
Bioulac-Sage, P.5
Laurent, C.6
-
5
-
-
84867210498
-
Targeted integration of a rAAV vector into the AAVS1 region
-
Ward, P, and Walsh, CE. (2012). Targeted integration of a rAAV vector into the AAVS1 region. Virology 433: 356-366
-
(2012)
Virology
, vol.433
, pp. 356-366
-
-
Ward, P.1
Walsh, C.E.2
-
6
-
-
84946923297
-
Structural insights into the assembly of the adeno-Associated virus type 2 Rep68 protein on the integration site AAVS1
-
Musayev, FN, Zarate-Perez, F, Bishop, C, Burgner, JW, and Escalante, CR. (2015). Structural insights into the assembly of the adeno-Associated virus type 2 Rep68 protein on the integration site AAVS1. J Biol Chem 290: 27487-27499
-
(2015)
J Biol Chem
, vol.290
, pp. 27487-27499
-
-
Musayev, F.N.1
Zarate-Perez, F.2
Bishop, C.3
Burgner, J.W.4
Escalante, C.R.5
-
7
-
-
0034084825
-
DNA sequence motifs which direct adeno-Associated virus site-specific integration in a model system
-
Meneses, P, Berns, KI, and Winocour, E. (2000). DNA sequence motifs which direct adeno-Associated virus site-specific integration in a model system. J Virol 74: 6213-6216
-
(2000)
J Virol
, vol.74
, pp. 6213-6216
-
-
Meneses, P.1
Berns, K.I.2
Winocour, E.3
-
8
-
-
0032978609
-
Development of animal models for adeno-Associated virus site-specific integration
-
Rizzuto, G, Gorgoni, B, Cappelletti, M, Lazzaro, D, Gloaguen, I, Poli, V, et al. (1999). Development of animal models for adeno-Associated virus site-specific integration. J Virol 73: 2517-2526
-
(1999)
J Virol
, vol.73
, pp. 2517-2526
-
-
Rizzuto, G.1
Gorgoni, B.2
Cappelletti, M.3
Lazzaro, D.4
Gloaguen, I.5
Poli, V.6
-
9
-
-
84855781461
-
Adeno-Associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19
-
Huang, S, Kawabe, Y, Ito, A, and Kamihira, M. (2012). Adeno-Associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19. Biochem Biophys Res Commun 417: 78-83
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 78-83
-
-
Huang, S.1
Kawabe, Y.2
Ito, A.3
Kamihira, M.4
-
10
-
-
53649109805
-
Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562
-
Howden, SE, Voullaire, L, Wardan, H, Williamson, R, and Vadolas, J. (2008). Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562. Gene Ther 15: 1372-1383
-
(2008)
Gene Ther
, vol.15
, pp. 1372-1383
-
-
Howden, S.E.1
Voullaire, L.2
Wardan, H.3
Williamson, R.4
Vadolas, J.5
-
11
-
-
37549059146
-
Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector
-
Cortés, ML, Oehmig, A, Saydam, O, Sanford, JD, Perry, KF, Fraefel, C, et al. (2008). Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector. Mol Ther 16: 81-88
-
(2008)
Mol Ther
, vol.16
, pp. 81-88
-
-
Cortés, M.L.1
Oehmig, A.2
Saydam, O.3
Sanford, J.D.4
Perry, K.F.5
Fraefel, C.6
-
12
-
-
67349204467
-
A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1transgenic mice for expression of hFIX
-
Xu, ZX, Chen, JZ, Yue, YB, Zhang, JQ, Li, ZH, Feng, DM, et al. (2009). A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1transgenic mice for expression of hFIX. Gene Ther 16: 589-595
-
(2009)
Gene Ther
, vol.16
, pp. 589-595
-
-
Xu, Z.X.1
Chen, J.Z.2
Yue, Y.B.3
Zhang, J.Q.4
Li, Z.H.5
Feng, D.M.6
-
13
-
-
84906975820
-
Adeno-Associated virus type 2 wild-Type, and vector-mediated genomic integration profiles of human diploid fibroblasts analyzed by thirdgeneration PacBio DNA sequencing
-
Hüser, D, Gogol-Döring, A, Chen, W, and Heilbronn, R. (2014). Adeno-Associated virus type 2 wild-Type, and vector-mediated genomic integration profiles of human diploid fibroblasts analyzed by thirdgeneration PacBio DNA sequencing. J Virol 88: 11253-11263
-
(2014)
J Virol
, vol.88
, pp. 11253-11263
-
-
Hüser, D.1
Gogol-Döring, A.2
Chen, W.3
Heilbronn, R.4
-
14
-
-
84931092873
-
Presence of a trs-like motif promotes Rep-mediated wild-Type adeno-Associated virus type 2 integration
-
Petri, K, Gabriel, R, Agundez, L, Fronza, R, Afzal, S, Kaeppel, C, et al. (2015). Presence of a trs-like motif promotes Rep-mediated wild-Type adeno-Associated virus type 2 integration. J Virol 89: 7428-7432
-
(2015)
J Virol
, vol.89
, pp. 7428-7432
-
-
Petri, K.1
Gabriel, R.2
Agundez, L.3
Fronza, R.4
Afzal, S.5
Kaeppel, C.6
-
15
-
-
84922152390
-
Vector design influences hepatic genotoxicity after adeno-Associated virus gene therapy
-
Chandler, RJ, LaFave, MC, Varshney, GK, Trivedi, NS, Carrillo-Carrasco, N, et al. (2015). Vector design influences hepatic genotoxicity after adeno-Associated virus gene therapy. J Clin Invest. 125: 870-880
-
(2015)
J Clin Invest
, vol.125
, pp. 870-880
-
-
Chandler, R.J.1
LaFave, M.C.2
Varshney, G.K.3
Trivedi, N.S.4
Carrillo-Carrasco, N.5
-
16
-
-
84952067002
-
Adeno-Associated virus type 2, and hepatocellular carcinoma?
-
Berns, KI, Byrne, BJ, Flotte, TR, Gao, G, Hauswirth, WW, Herzog, RW, et al. (2015). Adeno-Associated virus type 2, and hepatocellular carcinoma?. Hum Gene Ther 26: 779-781
-
(2015)
Hum Gene Ther
, vol.26
, pp. 779-781
-
-
Berns, K.I.1
Byrne, B.J.2
Flotte, T.R.3
Gao, G.4
Hauswirth, W.W.5
Herzog, R.W.6
|