A randomized trial of mexiletine in ALS

Neurology

Volumn 86, Issue 16, 2016, Pages 1474-1481

  Weiss, Michael D ^a   Macklin, Eric A ^b   Simmons, Zachary ^c   Knox, Angela S ^b   Greenblatt, David J ^d   Atassi, Nazem ^b   Graves, Michael ^e   Parziale, Nicholas ^e   Salameh, Johnny S ^f   Quinn, Colin ^f   Brown, Robert H ^f   Distad, Jane B ^a   Trivedi, Jaya ^g   Shefner, Jeremy M ^h   Barohn, Richard J ⁱ   Pestronk, Alan ^j   Swenson, Andrea ^k   Cudkowicz, Merit E ^b  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UCLA MEDICAL CENTER   (United States)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF TEXAS AT DALLAS   (United States)

^h BARROW NEUROLOGICAL INSTITUTE   (United States)

ⁱ UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^j WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MEXILETINE; PLACEBO; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; AMYOTROPHIC LATERAL SCLEROSIS FUNCTIONAL RATING SCALE REVISED; ARTICLE; BLOOD SAMPLING; CEREBROSPINAL FLUID; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FALLING; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE CRAMP; MUSCLE CRAMP FREQUENCY; MUSCULOSKELETAL SYSTEM PARAMETERS; NAUSEA; NEUROLOGIC DISEASE ASSESSMENT; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY DISTRESS; SIDE EFFECT; SLOW VITAL CAPACITY; SPORADIC AMYOTROPHIC LATERAL SCLEROSIS; TREMOR; BODY EQUILIBRIUM; CLINICAL TRIAL; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECTS; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; TREATMENT OUTCOME;

AMYOTROPHIC LATERAL SCLEROSIS; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MEXILETINE; MIDDLE AGED; MUSCLE CRAMP; POSTURAL BALANCE; TREATMENT OUTCOME; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84964335739     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002507     Document Type: Article

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