Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial

Retrovirology

Volumn 13, Issue 1, 2016, Pages

  Loret, Erwann P ^a   Darque, Albert ^a,b   Jouve, Elisabeth ^c   Loret, Elvenn A ^a   Nicolino Brunet, Corinne ^a   Morange, Sophie ^b   Castanier, Elisabeth ^b   Casanova, Josiane ^b   Caloustian, Christine ^b   Bornet, Charléric ^b   Coussirou, Julie ^b   Boussetta, Jihen ^b   Couallier, Vincent ^d   Blin, Olivier ^c   Dussol, Bertrand ^b   Ravaux, Isabelle ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^c TIMONE HOSPITAL   (France)

^d UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

ART interruption; Clinical trial; HIV; Tat; Vaccine

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN G; TRANSACTIVATOR PROTEIN; VIRUS DNA; VIRUS RNA; ANTIRETROVIRUS AGENT;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FACE PAIN; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; INFECTION CONTROL; MALE; OUTCOME ASSESSMENT; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; TUBERCULOSIS; BLOOD; CLINICAL TRIAL; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; INTRADERMAL DRUG ADMINISTRATION; MIDDLE AGED; TREATMENT OUTCOME; VIRUS LOAD;

ADULT; AIDS VACCINES; ANTI-RETROVIRAL AGENTS; DNA, VIRAL; DOUBLE-BLIND METHOD; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; INJECTIONS, INTRADERMAL; MALE; MIDDLE AGED; RNA, VIRAL; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OUTCOME; VIRAL LOAD;

EID: 84964330163     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/s12977-016-0251-3     Document Type: Article

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