Cinnamic acid amides from Tribulus terrestris displaying uncompetitive α-glucosidase inhibition

European Journal of Medicinal Chemistry

Volumn 114, Issue , 2016, Pages 201-208

  Song, Yeong Hun ^a   Kim, Dae Wook ^a   Curtis Long, Marcus J ^b   Park, Chanin ^a   Son, Minky ^a   Kim, Jeong Yoon ^a   Yuk, Heung Joo ^a   Lee, Keun Woo ^a   Park, Ki Hun ^a  

^a Gyeongsang National University   (South Korea)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

Cinnamic acid amide; Molecular docking; Tribulus terrestris; Uncompetitive inhibition; Glucosidase

Indexed keywords

3 (4 HYDROXYPHENYL) N PHENYLETHYL ACRYLAMIDE; ALPHA GLUCOSIDASE; AMIDE; CARBONYL DERIVATIVE; CINNAMIC ACID; ENZYME INHIBITOR; GLUCOSIDASE; HYDROXYL GROUP; N (3,4 DIHYDROXYPHENETHYL) 3 (4 HYDROXYPHENYL) ACRYLAMIDE; N (4 FLUOROPHENETHYL) 3 (4 HYDROXYPHENYL) ACRYLAMIDE; N (4 HYDROXYPHENETHYL) CINNAMAMIDE; N CAFFEOYLTYRAMINE; N COUMAROYLTYRAMINE; N FERULOYLOCTOPAMINE; TERRESTRIAMIDE; TERRESTRIMINE; TRIBULUS TERRESTRIS EXTRACT; UNCLASSIFIED DRUG; CINNAMIC ACID DERIVATIVE; GLYCOSIDASE INHIBITOR;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG ISOLATION; ENZYME INHIBITION; HYDROGEN BOND; IC50; METABOLITE; MOLECULAR MODEL; NONHUMAN; TRIBULUS TERRESTRIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION; TRIBULUS;

ALPHA-GLUCOSIDASES; AMIDES; CINNAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOSIDE HYDROLASE INHIBITORS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TRIBULUS;

EID: 84964287485     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2016.02.044     Document Type: Article

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