Cell mechanics: The role of simulation

Computational Methods in Applied Sciences

Volumn 20, Issue , 2011, Pages 1-14

  Jacobs, Christopher R ^a   Kelly, Daniel J ^b  

^a Columbia University ^*  (United States)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84964265166     PISSN: 18713033     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-1254-6_1     Document Type: Conference Paper

References (66)

1. Jacobs CR, (2007) What Can We Learn About Biology from Finite Element Analysis. European Society for Biomechanics Summer Workshop. Trinity Collage Dublin.
2. Van der Meulen MC, Huiskes R (2002) Why mechanobiology? A survey article. J Biomech 35:401-14.
3. Huiskes R, Ruimerman R, Van Lenthe GH, Janssen JD, (2000) Effects of mechanical forces on maintenance and adaptation of form in trabecular bone. Nature 405:704-6.
4. Fernandes P, Rodrigues H, Jacobs C, (1999) A Model of Bone Adaptation Using a Global Optimisation Criterion Based on the Trajectorial Theory of Wolff. Comput Methods Biomech Biomed Engin 2:125-138.
5. Anderson AE, Ellis BJ, Weiss J A, (2007) Verification, validation and sensitivity studies in computational biomechanics. Comput Methods Biomech Biomed Engin 10:171-84.
6. Carl P, Schillers H, (2008) Elasticity measurement of living cells with an atomic force microscope: data acquisition and processing. Pflugers Arch 457: 551-9.
7. Cegonino J, Garcia Aznar JM, Doblare M, Palanca D, Seral B, Seral F, (2004) A comparative analysis of different treatments for distal femur fractures using the finite element method. Comput Methods Biomech Biomed Engin 7:245-56.
8. Jacobs CR, (1994) Numerical simulation of bone adaptation to mechanical load. Mechanical Engineering. Stanford, Stanford.
9. Wang Y, McNamara LM, Schaffler MB, Weinbaum S, (2008) Strain amplification and integrin based signaling in osteocytes. J Musculoskelet Neuronal Interact 8:332-4.
10. Lacroix D, Prendergast PJ (2002) A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading. J Biomech 35:1163-71.
11. Kelly DJ, Prendergast PJ, (2005) Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects. J Biomech 38:1413-22.
12. Khayyeri H, Checa S, Tagil M, Prendergast PJ (2009) Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach. J Orthop Res 27:1659-1666.
13. Andreykiv A, Van Keulen F, Prendergast PJ, (2008) Simulation of fracture healing incorporating mechanoregulation of tissue differentiation and dispersal/proliferation of cells. Biomech Model Mechanobiol 7:443-61.
14. Boccaccio A, Prendergast PJ, Pappalettere C, Kelly DJ, (2008) Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period. Med Biol Eng Comput 46:283-98.
15. Huiskes R, Van Driel WD, Prendergast PJ, Soballe K, (1997) A biomechanical regulatory model for periprosthetic fibrous-tissue differentiation. J Mater Sci Mater Med, 8:785-8.
16. Isaksson H, Wilson W, Van Donkelaar CC, Huiskes R, Ito K, (2006) Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing. J Biomech 39:1507-16.
17. Hayward LN, Morgan EF, (2009) Assessment of a mechano-regulation theory of skeletal tissue differentiation in an in vivo model of mechanically induced cartilage formation. Biomech Model Mechanobiol 8:447-455.
18. Checa S, Prendergast PJ, (2009) A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach. Ann Biomed Eng 37:129-45.
19. Nowlan NC, Murphy P, Prendergast PJ, (2007) Mechanobiology of embryonic limb development. Ann N Y Acad Sci 1101:389-411.
20. Nagel T, Kelly DJ, (2010) Mechano-regulation of mesenchymal stem cell differentiation and collagen organisation during skeletal tissue repair. Biomech Model Mechanobiol, 9, 359-72.
21. Khayyeri H, (2010) in Jacobs CR (Ed.). Valencia, Spain.
22. Vaziri A, Gopinath A, (2008) Cell and biomolecular mechanics in silico. Nat Mater 7:15-23.
23. Skalak R, Keller SR, Secomb TW, (1981) Mechanics of blood flow. J Biomech Eng 103:102-15.
24. Skalak R, Dong C, Zhu C, (1990) Passive deformations and active motions of leukocytes. J Biomech Eng 112:295-302.
25. Dong C, Skalak R, (1992) Leukocyte deformability: finite element modeling of large viscoelastic deformation. J Theor Biol 158:173-93.
26. DiMilla PA, Barbee K, Lauffenburger DA, (1991) Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys J 60:15-37.
27. N'Dri NA, Shyy W, Tran-Son-Tay R (2003) Computational modeling of cell adhesion and movement using a continuum-kinetics approach. Biophys J 85:2273-86.
28. Ward MD, Dembo M, Hammer DA, (1994) Kinetics of cell detachment: peeling of discrete receptor clusters. Biophys J 67:2522-34.
29. Dong C, Lei XX, (2000) Biomechanics of cell rolling: shear flow, cell-surface adhesion, and cell deformability. J Biomech 33:35-43.
30. Kan HC, Udaykumar HS, Shyy W, Tran-Son-Tay R, (1999) Numerical analysis of the deformation of an adherent drop under shear flow. J Biomech Eng 121:160-9.
31. Pozrikidis C, (2003) Numerical simulation of the flow-induced deformation of red blood cells. Ann Biomed Eng 31:1194-205.
32. Bursa J, Lebis R, Janicek P, (2006) FE models of stress-strain states in vascular smooth muscle cell. Technol Health Care 14:311-20.
33. Wu JZ, Herzog W, (2000) Finite element simulation of location-and time-dependent mechanical behavior of chondrocytes in unconfined compression tests. Ann Biomed Eng 28:318-30.
34. Ng L, Hung HH, Sprunt A, Chubinskaya S, Ortiz C, Grodzinsky A (2007) Nanomechanical properties of individual chondrocytes and their developing growth factor-stimulated pericellular matrix. J Biomech 40:1011-23.
35. Vaziri A, Mofrad MR, (2007) Mechanics and deformation of the nucleus in micropipette aspiration experiment. J Biomech 40:2053-62.
36. Kwon RY, Lew AJ, Jacobs CR, (2008) A microstructurally informed model for the mechanical response of three-dimensional actin networks. Comput Methods Biomech Biomed Engin 11:407-18.
37. Unnikrishnan GU, Unnikrishnan VU, Reddy JN, (2007) Constitutive material modeling of cell: a micromechanics approach. J Biomech Eng 129:315-23.
38. Kim T, Hwang W, Lee H, Kamm RD, (2009) Computational analysis of viscoelastic properties of crosslinked actin networks. PLoS Comput Biol 5: e1000439.
39. Colombelli J, Besser A, Kress H, Reynaud EG, Girard P, Caussinus E, Haselmann U, Small JV, Schwarz US, Stelzer, EH, (2009) Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization. J Cell Sci 122:1665-79.
40. Jaasma MJ, Jackson WM, Tang RY, Keaveny TM, (2007) Adaptation of cellular mechanical behavior to mechanical loading for osteoblastic cells. J Biomech 40:1938-45.
41. You L, Temiyasathit S, Coyer SR, Garcia AJ, (2008) Bone cells grown on micropatterned surfaces are more sensitive to fluid shear stress. Cell and Molecular Bioengineering 1:182-188.
42. Arnsdorf EJ, Tummala P, Kwon RY, Jacobs CR, (2009) Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics. J Cell Sci 122:546-53.
43. Ingber DE, (1998) The architecture of life. Sci Am, 278:48-57.
44. Sultan C, Stamenovic D, Ingber DE, (2004) A computational tensegrity model predicts dynamic rheological behaviors in living cells. Ann Biomed Eng, 32:520-30.
45. Volokh KY, (2003) Cytoskeletal architecture and mechanical behavior of living cells. Biorheology, 40:213-20.
46. Baker EL, Zaman MH, (2009) The biomechanical integrin. J Biomech 43:38-44.
47. Brown FL, (2008) Elastic modeling of biomembranes and lipid bilayers. Annu Rev Phys Chem, 59:685-712.
48. Allen KB, Sasoglu FM, LAYTON BE, (2009) Cytoskeleton-membrane interactions in neuronal growth cones: a finite analysis study. J Biomech Eng, 131:021006.
49. Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA, (2008) Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane. J Biomech Eng 130:031007.
50. Ananthakrishnan R, Guck J, Wottawah F, Schinkinger S, Lincoln B, Romeyke M, Moon T, Kas J, (2006) Quantifying the contribution of actin networks to the elastic strength of fibroblasts. J Theor Biol 242:502-516.
51. Brodland GW, Viens D, Veldhuis JH, (2007) A new cell-based FE model for the mechanics of embryonic epithelia. Comput Methods Biomech Biomed Engin 10:121-8.
52. Young J, Mitran S, (2010) A numerical model of cellular blebbing: A volume-conserving, fluid-structure interaction model of the entire cell. J Biomech. 42:210:20.
53. Duncan RK, Grant JW, (1997) A finite-element model of inner ear hair bundle micromechanics. Hear Res 104:15-26.
54. Cotton JR, Grant JW, (2000) A finite element method for mechanical response of hair cell ciliary bundles. J Biomech Eng 122:44-50.
55. Hartmann C, Delgado A, (2004) Numerical simulation of the mechanics of a yeast cell under high hydrostatic pressure. J Biomech 37:977-87.
56. McGarry JG, Klein-Nulend J, Mullender MG, Prendergast PJ, (2005) A comparison of strain and fluid shear stress in stimulating bone cell responses - a computational and experimental study. FASEB J 19:482-4.
57. Charras GT, Horton MA, (2002) Determination of cellular strains by combined atomic force microscopy and finite element modeling. Biophys J 83:858-79.
58. Boey SK, Boal DH, Discher DE, (1998) Simulations of the erythrocyte cytoskeleton at large deformation. I. Microscopic models. Biophys J 75:1573-83.
59. Bevill G, Keaveny TM, (2009) Trabecular bone strength predictions using finite element analysis of micro-scale images at limited spatial resolution. Bone 44:579-84.
60. Pahr DH, Zysset PK, (2009) A comparison of enhanced continuum FE with micro FE models of human vertebral bodies. J Biomech 42:455-62.
61. Van Rietbergen B, Muller R, Ulrich D, Ruegsegger P, Huiskes R, (1999) Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions. J Biomech 32:443-51.
62. Hartmann D, (2010) A multiscale model for red blood cell mechanics. Biomech Model Mechanobiol 9:1-17.
63. Dillon RH, Fauci LJ, (2000) An integrative model of internal axoneme mechanics and external fluid dynamics in ciliary beating. J Theor Biol 207:415-30.
64. Malone AM, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, Jacobs CR, (2007) Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci U S A 104:13325-30.
65. Anderson CT, Castillo AB, Brugmann SA, Helms JA, Jacobs CR, Stearns T, (2008) Primary cilia: cellular sensors for the skeleton. Anat Rec (Hoboken) 291:1074-8.
66. Schwartz EA, Leonard ML, Bizios R, Bowser SS, (1997) Analysis and modeling of the primary cilium bending response to fluid shear. Am J Physiol 272: F132-8.