Squaraines bearing halogenated moieties as anticancer photosensitizers: Synthesis, characterization and biological evaluation

European Journal of Medicinal Chemistry

Volumn 113, Issue , 2016, Pages 187-197

  Serpe, Loredana ^a   Ellena, Silvano ^a   Barbero, Nadia ^a   Foglietta, Federica ^a   Prandini, Federica ^a   Gallo, Maria Pia ^a   Levi, Renzo ^a   Barolo, Claudia ^a   Canaparo, Roberto ^a   Visentin, Sonja ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Cancer; Photodynamic therapy; Photosensitizers; Singlet oxygen; Squaraines

Indexed keywords

ANTINEOPLASTIC AGENT; CARBON; CYTOCHROME C; DYE; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PHOTOSENSITIZING AGENT; PROTEIN; PROTEIN NQO1; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; SQUARAINE DERIVATIVE; UNCLASSIFIED DRUG; CYCLOBUTANE DERIVATIVE; HALOGEN; PHENOL DERIVATIVE; SQUARAINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DESTRUCTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; ENERGY TRANSFER; ENZYME RELEASE; HUMAN; HUMAN CELL; PHOTOACTIVATION; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; CELL DEATH; CELL PROLIFERATION; CYCLOBUTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HALOGENS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHENOLS; PHOTOSENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84964240822     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2016.02.035     Document Type: Article

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