Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure

Critical Care

Volumn 20, Issue 1, 2016, Pages

  Roca, Oriol ^a,b   Hernández, Gonzalo ^c   Díaz Lobato, Salvador ^d   Carratalá, José M ^e   Gutiérrez, Rosa M ^f   Masclans, Joan R ^b,g  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL VIRGEN DE LA SALUD   (Spain)

^d HOSPITAL RAMÓN Y CAJAL   (Spain)

^e Alicante General Hospital   (Spain)

^f HOSPITAL DE CRUCES   (Spain)

^g HOSPITAL DEL MAR   (Spain)

Author keywords

High flow nasal cannula; High flow oxygen therapy; Respiratory failure

Indexed keywords

SALBUTAMOL;

ACUTE RESPIRATORY FAILURE; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ASSISTED VENTILATION; BREATHING; BREATHING RATE; BRONCHIECTASIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; ENDOTRACHEAL INTUBATION; EXTUBATION; GAS DIFFUSION; HEATING; HEMODYNAMICS; HIGH FLOW NASAL CANNULA THERAPY; HUMAN; HUMIDIFIER; HYPOVENTILATION; HYPOXEMIA; INVASIVE PROCEDURE; LUNG DEAD SPACE; MEDICAL NEBULIZER; METABOLISM; MUCOCILIARY CLEARANCE; MULTICENTER STUDY (TOPIC); NASAL CANNULA; NONHUMAN; NONINVASIVE VENTILATION; OXYGEN THERAPY; OXYGENATION; PEAK INSPIRATORY FLOW; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY FAILURE; REVIEW; SLEEP DISORDERED BREATHING; TRACHEOSTOMY; CANNULA; PROCEDURES; RESPIRATORY INSUFFICIENCY;

ADULT; CANNULA; HUMANS; HUMIDIFIERS; OXYGEN INHALATION THERAPY; RESPIRATORY INSUFFICIENCY;

EID: 84964237870     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-016-1263-z     Document Type: Review

References (90)

1. Anderson NJ, Cassidy PE, Janssen LL, Dengel DR. Peak inspiratory flows of adults exercising at light, moderate and heavy workloads. J Int Soc Respir Prot. 2006;23:53-63.
2. Masclans JR, Roca O. High-flow oxygen therapy in acute respiratory failure. Clin Pulm Med. 2012;19(3):127-30. doi: 10.1097/CPM.0b013e3182514f29.
3. Parke RL, McGuinness SP. Pressures delivered by nasal high flow oxygen during all phases of the respiratory cycle. Respir Care. 2013;58(10):1621-4. doi: 10.4187/respcare.02358.
4. Parke R, McGuinness S, Eccleston M. Nasal high-flow therapy delivers low level positive airway pressure. Br J Anaesth. 2009;103(6):886-90. doi: 10.1093/bja/aep280.
5. Parke RL, Bloch A, McGuinness SP. Effect of very-high-flow nasal therapy on airway pressure and end-expiratory lung impedance in healthy volunteers. Respir Care. 2015;60(10):1397-403. doi: 10.4187/respcare.04028.
6. Chatila W, Nugent T, Vance G, et al. The effects of high-flow vs low-flow oxygen on exercise in advanced obstructive airways disease. Chest. 2004;126(4):1108-15. doi: 10.1378/chest.126.4.1108.
7. Groves N, Tobin A. High flow nasal oxygen generates positive airway pressure in adult volunteers. Aust Crit Care. 2007;20(4):126-31. doi: 10.1016/j.aucc.2007.08.001.
8. Chanques G, Riboulet F, Molinari N, et al. Comparison of three high flow oxygen therapy delivery devices: a clinical physiological cross-over study. Minerva Anestesiol. 2013;79(12):1344-55. Available at: http://www.ncbi.nlm.nih.gov/pubmed/23857440. Accessed October 26, 2015.
9. Hinz J, Hahn G, Neumann P, et al. End-expiratory lung impedance change enables bedside monitoring of end-expiratory lung volume change. Intensive Care Med. 2003;29(1):37-43. doi: 10.1007/s00134-002-1555-4.
10. Corley A, Caruana LR, Barnett AG, et al. Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients. Br J Anaesth. 2011;107(6):998-1004. doi: 10.1093/bja/aer265.
11. Riera J, Pérez P, Cortés J, et al. Effect of high-flow nasal cannula and body position on end-expiratory lung volume: a cohort study using electrical impedance tomography. Respir Care. 2013;58(4):589-96. doi: 10.4187/respcare.02086.
12. Dysart K, Miller TL, Wolfson MR, Shaffer TH. Research in high flow therapy: mechanisms of action. Respir Med. 2009;103(10):1400-5. doi: 10.1016/j.rmed.2009.04.007.
13. Spence CJT, Buchmann NA, Jermy MC. Unsteady flow in the nasal cavity with high flow therapy measured by stereoscopic PIV. Exp Fluids. 2012;52(3):569-79. doi: 10.1007/s00348-011-1044-z.
14. Frizzola M, Miller TL, Rodriguez ME, et al. High-flow nasal cannula: impact on oxygenation and ventilation in an acute lung injury model. Pediatr Pulmonol. 2011;46(1):67-74. doi: 10.1002/ppul.21326.
15. Chanques G, Constantin J-M, Sauter M, et al. Discomfort associated with underhumidified high-flow oxygen therapy in critically ill patients. Intensive Care Med. 2009;35(6):996-1003. doi: 10.1007/s00134-009-1456-x.
16. Roca O, Riera J, Torres F, Masclans JR. High-flow oxygen therapy in acute respiratory failure. Respir Care. 2010;55(4):408-13. Available at: http://www.ncbi.nlm.nih.gov/pubmed/20406507. Accessed October 26, 2015.
17. Kilgour E, Rankin N, Ryan S, Pack R. Mucociliary function deteriorates in the clinical range of inspired air temperature and humidity. Intensive Care Med. 2004;30(7):1491-4. doi: 10.1007/s00134-004-2235-3.
18. Chidekel A, Zhu Y, Wang J, et al. The effects of gas humidification with high-flow nasal cannula on cultured human airway epithelial cells. Pulm Med. 2012;2012:380686. doi: 10.1155/2012/380686.
19. Vargas F, Saint-Leger M, Boyer A, et al. Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Respir Care. 2015;60(10):1369-76. doi: 10.4187/respcare.03814.
20. Fontanari P, Burnet H, Zattara-Hartmann MC, Jammes Y. Changes in airway resistance induced by nasal inhalation of cold dry, dry, or moist air in normal individuals. J Appl Physiol. 1996;81(4):1739-43. Available at: http://www.ncbi.nlm.nih.gov/pubmed/8904594. Accessed January 7, 2016.
21. Miller MJ, DiFiore JM, Strohl KP, Martin RJ. Effects of nasal CPAP on supraglottic and total pulmonary resistance in preterm infants. J Appl Physiol. 1990;68(1):141-6. Available at: http://www.ncbi.nlm.nih.gov/pubmed/2179206. Accessed October 26, 2015.
22. Sztrymf B, Messika J, Mayot T, et al. Impact of high-flow nasal cannula oxygen therapy on intensive care unit patients with acute respiratory failure: a prospective observational study. J Crit Care. 2012;27(3):324. e9-13. doi: 10.1016/j.jcrc.2011.07.075.
23. Sztrymf B, Messika J, Bertrand F, et al. Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med. 2011;37(11):1780-6. doi: 10.1007/s00134-011-2354-6.
24. Rello J, Pérez M, Roca O, et al. High-flow nasal therapy in adults with severe acute respiratory infection: a cohort study in patients with 2009 influenza A/H1N1v. J Crit Care. 2012;27(5):434-9. doi: 10.1016/j.jcrc.2012.04.006.
25. Roca O, Pérez-Terán P, Masclans JR, et al. Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy: high flow nasal cannula in heart failure. J Crit Care. 2013;28(5):741-6. doi: 10.1016/j.jcrc.2013.02.007.
26. Moreno FL, Hagan AD, Holmen JR, et al. Evaluation of size and dynamics of the inferior vena cava as an index of right-sided cardiac function. Am J Cardiol. 1984;53(4):579-85. Available at: http://www.ncbi.nlm.nih.gov/pubmed/6695787. Accessed February 15, 2016.
27. Barbier C, Loubières Y, Schmit C, et al. Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Med. 2004;30(9):1740-6. doi: 10.1007/s00134-004-2259-8.
28. Feissel M, Michard F, Faller J-P, Teboul J-L. The respiratory variation in inferior vena cava diameter as a guide to fluid therapy. Intensive Care Med. 2004;30(9):1834-7. doi: 10.1007/s00134-004-2233-5.
29. Carratalá Perales JM, Llorens P, Brouzet B, et al. High-flow therapy via nasal cannula in acute heart failure. Rev Esp Cardiol. 2011;64(8):723-5. doi: 10.1016/j.recesp.2010.10.034.
30. Hyun Cho W, Ju Yeo H, Hoon Yoon S, et al. High-flow nasal cannula therapy for acute hypoxemic respiratory failure in adults: a retrospective analysis. Intern Med. 2015;54(18):2307-13. doi: 10.2169/internalmedicine.54.4266.
31. Frat J-P, Brugiere B, Ragot S, et al. Sequential application of oxygen therapy via high-flow nasal cannula and noninvasive ventilation in acute respiratory failure: an observational pilot study. Respir Care. 2015;60(2):170-8. doi: 10.4187/respcare.03075.
32. Schwabbauer N, Berg B, Blumenstock G, et al. Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol. 2014;14:66. doi: 10.1186/1471-2253-14-66.
33. Roca O, de Acilu MG, Caralt B, et al. Humidified high flow nasal cannula supportive therapy improves outcomes in lung transplant recipients readmitted to the intensive care unit because of acute respiratory failure. Transplantation. 2015;99(5):1092-8. doi: 10.1097/TP.0000000000000460.
34. Frat J-P, Thille AW, Mercat A, et al. High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med. 2015;372(23):2185-96. doi: 10.1056/NEJMoa1503326.
35. Peters SG, Holets SR, Gay PC. High-flow nasal cannula therapy in do-not-intubate patients with hypoxemic respiratory distress. Respir Care. 2013;58(4):597-600. doi: 10.4187/respcare.01887.
36. Lenglet H, Sztrymf B, Leroy C, et al. Humidified high flow nasal oxygen during respiratory failure in the emergency department: feasibility and efficacy. Respir Care. 2012;57(11):1873-8. doi: 10.4187/respcare.01575.
37. Simon M, Braune S, Frings D, et al. High-flow nasal cannula oxygen versus non-invasive ventilation in patients with acute hypoxaemic respiratory failure undergoing flexible bronchoscopy--a prospective randomised trial. Crit Care. 2014;18(6):712. doi: 10.1186/s13054-014-0712-9.
38. Lucangelo U, Vassallo FG, Marras E, et al. High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy. Crit Care Res Pract. 2012;2012:506382. doi: 10.1155/2012/506382.
39. Tiruvoipati R, Lewis D, Haji K, Botha J. High-flow nasal oxygen vs high-flow face mask: a randomized crossover trial in extubated patients. J Crit Care. 2010;25(3):463-8. doi: 10.1016/j.jcrc.2009.06.050.
40. Rittayamai N, Tscheikuna J, Rujiwit P. High-flow nasal cannula versus conventional oxygen therapy after endotracheal extubation: a randomized crossover physiologic study. Respir Care. 2014;59(4):485-90. doi: 10.4187/respcare.02397.
41. Maggiore SM, Idone FA, Vaschetto R, et al. Nasal high-flow vs Venturi mask oxygen therapy after extubation: effects on oxygenation, comfort and clinical outcome. Am J Respir Crit Care Med. 2014;190(3):282-8. doi: 10.1164/rccm.201402-0364OC.
42. Vourc'h M, Asfar P, Volteau C, et al. High-flow nasal cannula oxygen during endotracheal intubation in hypoxemic patients: a randomized controlled clinical trial. Intensive Care Med. 2015;41(9):1538-48. doi: 10.1007/s00134-015-3796-z.
43. Miguel-Montanes R, Hajage D, Messika J, et al. Use of high-flow nasal cannula oxygen therapy to prevent desaturation during tracheal intubation of intensive care patients with mild-to-moderate hypoxemia. Crit Care Med. 2015;43(3):574-83. doi: 10.1097/CCM.0000000000000743.
44. Stéphan F, Barrucand B, Petit P, et al. High-flow nasal oxygen vs noninvasive positive airway pressure in hypoxemic patients after cardiothoracic surgery. JAMA. 2015;313(23):2331-9. doi: 10.1001/jama.2015.5213.
45. Corley A, Bull T, Spooner AJ, et al. Direct extubation onto high-flow nasal cannulae post-cardiac surgery versus standard treatment in patients with a BMI ≥30: a randomised controlled trial. Intensive Care Med. 2015;41(5):887-94. doi: 10.1007/s00134-015-3765-6.
46. Parke RL, McGuinness SP, Eccleston ML. A preliminary randomized controlled trial to assess effectiveness of nasal high-flow oxygen in intensive care patients. Respir Care. 2011;56(3):265-70. doi: 10.4187/respcare.00801.
47. Parke R, McGuinness S, Dixon R, Jull A. Open-label, phase II study of routine high-flow nasal oxygen therapy in cardiac surgical patients. Br J Anaesth. 2013;111(6):925-31. doi: 10.1093/bja/aet262.
48. Jones PG, Kimona S, Doran O, et al. Randomized controlled trial of humidified high-flow nasal oxygen for acute respiratory distress in the emergency department: the HOT-ER study. Respir Care. 2015;61(3):291-9. doi: 10.4187/respcare.04252.
49. Nagata K, Morimoto T, Fujimoto D, et al. Efficacy of high-flow nasal cannula therapy in acute hypoxemic respiratory failure: decreased use of mechanical ventilation. Respir Care. 2015;60(10):1390-6. doi: 10.4187/respcare.04026.
50. Gaunt KA, Spilman SK, Halub ME, et al. High-flow nasal cannula in a mixed adult ICU. Respir Care. 2015;60(10):1383-9. doi: 10.4187/respcare.04016.
51. Lemiale V, Mokart D, Mayaux J, et al. The effects of a 2-h trial of high-flow oxygen by nasal cannula versus Venturi mask in immunocompromised patients with hypoxemic acute respiratory failure: a multicenter randomized trial. Crit Care. 2015;19(1):380. doi: 10.1186/s13054-015-1097-0.
52. Mokart D, Geay C, Chow-Chine L, et al. High-flow oxygen therapy in cancer patients with acute respiratory failure. Intensive Care Med. 2015;41(11):2008-10. doi: 10.1007/s00134-015-3994-8.
53. Kang BJ, Koh Y, Lim C-M, et al. Failure of high-flow nasal cannula therapy may delay intubation and increase mortality. Intensive Care Med. 2015;41(4):623-32. doi: 10.1007/s00134-015-3693-5.
54. Rittayamai N, Tscheikuna J, Praphruetkit N, Kijpinyochai S. Use of high-flow nasal cannula for acute dyspnea and hypoxemia in the emergency department. Respir Care. 2015;60(10):1377-82. doi: 10.4187/respcare.03837.
55. Messika J, Ben Ahmed K, Gaudry S, et al. Use of high-flow nasal cannula oxygen therapy in subjects with ARDS: a 1-year observational study. Respir Care. 2015;60(2):162-9. doi: 10.4187/respcare.03423.
56. Schlapbach LJ, Schaefer J, Brady A-M, et al. High-flow nasal cannula (HFNC) support in interhospital transport of critically ill children. Intensive Care Med. 2014;40(4):592-9. doi: 10.1007/s00134-014-3226-7.
57. Ricard J-D, Messika J, Sztrymf B, Gaudry S. Impact on outcome of delayed intubation with high-flow nasal cannula oxygen: is the device solely responsible? Intensive Care Med. 2015;41(6):1157-8. doi: 10.1007/s00134-015-3766-5.
58. Ranieri VM, Rubenfeld GD, Thompson BT, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526-33. doi: 10.1001/jama.2012.5669.
59. Calfee CS. ARDS in 2015: new clinical directions, new biological insights. Lancet Respir Med. 2015;3(12):912-3. doi: 10.1016/S2213-2600(15)00425-7.
60. Antonelli M, Conti G, Esquinas A, et al. A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome. Crit Care Med. 2007;35(1):18-25. doi: 10.1097/01.CCM.0000251821.44259.F3.
61. Lomas C, Roca O, Álvarez A, Masclans JR. Fibroscopy in patients with hypoxemic respiratory insufficiency: Utility of the high-flow nasal cannula. Respir Med CME. 2009;2(3):121-4.
62. Miyagi K, Haranaga S, Higa F, et al. Implementation of bronchoalveolar lavage using a high-flow nasal cannula in five cases of acute respiratory failure. Respir Investig. 2014;52(5):310-4. doi: 10.1016/j.resinv.2014.06.006.
63. Futier E, Paugam-Burtz C, Constantin J-M, et al. The OPERA trial--comparison of early nasal high flow oxygen therapy with standard care for prevention of postoperative hypoxemia after abdominal surgery: study protocol for a multicenter randomized controlled trial. Trials. 2013;14:341. doi: 10.1186/1745-6215-14-341.
64. Hernandez G, Pedrosa A, Ortiz R, et al. The effects of increasing effective airway diameter on weaning from mechanical ventilation in tracheostomized patients: a randomized controlled trial. Intensive Care Med. 2013;39(6):1063-70. doi: 10.1007/s00134-013-2870-7.
65. Rea H, McAuley S, Jayaram L, et al. The clinical utility of long-term humidification therapy in chronic airway disease. Respir Med. 2010;104(4):525-33. doi: 10.1016/j.rmed.2009.12.016.
66. Donaldson GC, Seemungal TAR, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847-52. Available at: doi: 10.1136/thorax.57.10.847. Accessed October 3, 2015.
67. Bhowmik A, Seemungal TA, Sapsford RJ, et al. Comparison of spontaneous and induced sputum for investigation of airway inflammation in chronic obstructive pulmonary disease. Thorax. 1998;53(11):953-6. Available at: http://www.ncbi.nlm.nih.gov/pubmed/10193394. Accessed October 26, 2015.
68. Fuschillo S, De Felice A, Balzano G. Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms. Eur Respir J. 2008;31(2):396-406. doi: 10.1183/09031936.00069007.
69. Prescott E, Lange P, Vestbo J. Chronic mucus hypersecretion in COPD and death from pulmonary infection. Eur Respir J. 1995;8(8):1333-8. Available at: http://www.ncbi.nlm.nih.gov/pubmed/7489800. Accessed October 26, 2015.
70. Rogers DF. Mucus pathophysiology in COPD: differences to asthma, and pharmacotherapy. Monaldi Arch Chest Dis. 2000;55(4):324-32. Available at: http://www.ncbi.nlm.nih.gov/pubmed/11057087. Accessed October 26, 2015.
71. Hasani A, Chapman TH, McCool D, et al. Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis. Chron Respir Dis. 2008;5(2):81-6. doi: 10.1177/1479972307087190.
72. Storgaard LH, Frystyck M, Hockey H, Weinreich LM. Number of exacerbations in COPD patients on LTOT treated with a nasal high flow system. Eur Respir J. 2014 vol. 44 no. Suppl 58 P4730.
73. Okuda M, Kashio M, Tanaka N, et al. Nasal high-flow oxygen therapy system for improving sleep-related hypoventilation in chronic obstructive pulmonary disease: a case report. J Med Case Rep. 2014;8:341. doi: 10.1186/1752-1947-8-341.
74. Nilius G, Franke K-J, Domanski U, et al. Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure. Adv Exp Med Biol. 2013;755:27-34. doi: 10.1007/978-94-007-4546-9_4.
75. Nilius G, Domansky U, Franke KJ, Rühle KH, Schneider H. Nasal High Flow Oxygen Therapy Attenuates Nocturnal Hypoventilation In COPD Patients With Hypercapnic Respiratory Failure. Am J Respir Crit Care Med. 2013;187:A3102.
76. McGinley BM, Patil SP, Kirkness JP, et al. A nasal cannula can be used to treat obstructive sleep apnea. Am J Respir Crit Care Med. 2007;176(2):194-200. doi: 10.1164/rccm.200609-1336OC.
77. Haba-Rubio J, Andries D, Rey V, et al. Effect of transnasal insufflation on sleep disordered breathing in acute stroke: a preliminary study. Sleep Breath. 2012;16(3):759-64. doi: 10.1007/s11325-011-0572-3.
78. Epstein AS, Hartridge-Lambert SK, Ramaker JS, et al. Humidified high-flow nasal oxygen utilization in patients with cancer at Memorial Sloan-Kettering Cancer Center. J Palliat Med. 2011;14(7):835-9. doi: 10.1089/jpm.2011.0005.
79. Lee HY, Rhee CK, Lee JW. Feasibility of high-flow nasal cannula oxygen therapy for acute respiratory failure in patients with hematologic malignancies: a retrospective single-center study. J Crit Care. 2015;30(4):773-7. doi: 10.1016/j.jcrc.2015.03.014.
80. Sunbul FS, Fink JB, Harwood R, et al. Comparison of HFNC, bubble CPAP and SiPAP on aerosol delivery in neonates: an in-vitro study. Pediatr Pulmonol. 2015;50(11):1099-106. doi: 10.1002/ppul.23123.
81. Perry SA, Kesser KC, Geller DE, et al. Influences of cannula size and flow rate on aerosol drug delivery through the Vapotherm humidified high-flow nasal cannula system. Pediatr Crit Care Med. 2013;14(5):e250-6. doi: 10.1097/PCC.0b013e31828a7f79.
82. MacLoughlin R, Power P, Wolny N, Duffy C. Evaluation of vibrating mesh nebulizer performance during nasal high flow therapy. J Aerosol Med Pulm Drug Deliv. 2013;26(2):A51.
83. Longest PW, Walenga RL, Son Y-J, Hindle M. High-efficiency generation and delivery of aerosols through nasal cannula during noninvasive ventilation. J Aerosol Med Pulm Drug Deliv. 2013;26(5):266-79. doi: 10.1089/jamp.2012.1006.
84. Bhashyam AR, Wolf MT, Marcinkowski AL, et al. Aerosol delivery through nasal cannulas: an in vitro study. J Aerosol Med Pulm Drug Deliv. 2008;21(2):181-8. doi: 10.1089/jamp.2007.0662.
85. Gea J, Orozco-Levi M, Gallart L. Increased inspiratory oxygen fractions (FIO2) using a conventional drug delivery nebuliser. Arch Bronconeumol. 2010;46(5):230-7. doi: 10.1016/j.arbres.2010.02.002.
86. Vincent J-L. High-flow oxygen cannula: a very effective method to correct severe hypoxemia. J Thorac Dis. 2015;7(8):E207-8. doi: 10.3978/j.issn.2072-1439.2015.07.33.
87. Pisani L, Corcione N, Nava S. Management of acute hypercapnic respiratory failure. Curr Opin Crit Care. 2016;22(1):45-52. doi: 10.1097/MCC.0000000000000269.
88. Brochard L, Mancebo J, Wysocki M, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med. 1995;333(13):817-22. doi: 10.1056/NEJM199509283331301.
89. Peter JV, Moran JL, Phillips-Hughes J, et al. Effect of non-invasive positive pressure ventilation (NIPPV) on mortality in patients with acute cardiogenic pulmonary oedema: a meta-analysis. Lancet. 2006;367(9517):1155-63. doi: 10.1016/S0140-6736(06)68506-1.
90. Díaz Lobato S, Mayoralas Alises S. Effectiveness of high-flow oxygen therapy with warm humidification in a COPD patient with chronic cough. Arch Bronconeumol. 2011;47(8):420-1. doi: 10.1016/j.arbres.2011.05.004.