Mucociliary function deteriorates in the clinical range of inspired air temperature and humidity

Intensive Care Medicine

Volumn 30, Issue 7, 2004, Pages 1491-1494

  Kilgour, Emma ^a   Rankin, Nigel ^b   Ryan, Stuart ^c   Pack, Rodger ^a  

^a MASSEY UNIVERSITY   (New Zealand)

^b MIDDLEMORE HOSPITAL   (New Zealand)

^c Fisher and Paykel Healthcare Limited   (New Zealand)

Author keywords

Epithelium; Humidification; Mucosa; Sheep; Trachea

Indexed keywords

AIR TEMPERATURE; ANIMAL TISSUE; ARTICLE; CILIARY MOTILITY; CONTROLLED STUDY; HISTOLOGY; HUMIDITY; MEMBRANE DAMAGE; MUCUS SECRETION; NONHUMAN; TRACHEA; TRACHEA MUCOSA;

EID: 3242690415     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-004-2235-3     Document Type: Article

References (13)

1. Williams R, Rankin N, Smith T, Galler D, Seakins P (1996) Relationship between the humidity and temperature of inspired gas and the function of the airway mucosa. Crit Care Med 24:1920-1929
2. Wills PJ, Pritchard K, Cole PJ (1998) Mucus transportability: the bovine trachea and frog palate models compared. Eur Respir J 12:837-841
3. Horstmann G, Iravani J, Norris MG, Richter H (1977) Influence of temperature and decreased water content of inspired air on the ciliated bronchial epithelium. A physiological and electron microscopical study. Acta Otolaryngol 84:124-131
4. Mercke U (1975) The influence of varying air humidity on mucociliary activity. Acta Otolaryngol 79:133-139
5. Stanek A, Brambrink A, Latorre F, Bender B, Kleemann P (1998) Effects of normobaric oxygen on ciliary beat frequency of human respiratory epithelium. Br J Anaesth 80:660-664
6. Seybold Z, Mariassy A, Stroh D, Kim C, Gazeroglu H, Wanner A (1990) Mucociliary interaction in vitro: effects of physiological and inflammatory stimuli. J Appl Physiol 68:1421-1426
7. Asmundsson T, Kilburn K (1970) Mucociliary clearance rates at various levels in dog lungs. Am Rev Respir Dis 102:388-397
8. Hirsch J, Tokayer J, Robinson M, Sackner M (1975) Effects of dry air and subsequent humidification on tracheal mucous velocity in dogs. J Appl Physiol 39:242-246
9. AARC Clinical Practice Guideline (1992) Humidification during mechanical ventilation. Respir Care 37:887-890
10. ISO 8185:1997 (1997) Humidifiers for medical use - General requirements for humidification systems. International Organisation for Standardisation
11. Ryan SN, Rankin N, Meyer E, Williams R (2002) Energy balance in the intubated human airway is an indicator of optimal gas conditioning. Crit Care Med 30:355-361
12. Alagar R, Garuccio J, Kudlak J, Nolder K (2000) Heated humidification reduces saline instillations, nebulized therapy, and cost in long-term ventilated patients. Am J Respir Crit Care Med 161:A552
13. Konrad F, Schiener R, Marx T, Georgieff M (1995) Ultrastructure and mucociliary transport of bronchial respiratory epithelium in intubated patients. Intensive Care Med 21:482-489