Development of a SPE-HPLC-MS/MS method for the determination of most prescribed pharmaceuticals and related metabolites in urban sewage samples

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 990, Issue , 2015, Pages 23-30

  Gurke, Robert ^a   Rossmann, Julia ^a   Schubert, Sara ^a   Sandmann, Tobias ^a   Rößler, Martin ^a   Oertel, Reinhard ^a   Fauler, Joachim ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Metabolites; Multi target; Pharmaceutical; Regional prescription data; Sewage; SPE HPLC MS MS

Indexed keywords

ANTIBIOTICS; BIOMOLECULES; CALIBRATION; CHROMATOGRAPHY; DRUG PRODUCTS; EFFLUENT TREATMENT; EFFLUENTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; METABOLITES; PHASE SEPARATION; SEWAGE; SEWAGE TREATMENT PLANTS;

ANGIOTENSIN CONVERTING ENZYME INHIBITORS; CHROMATOGRAPHIC SEPARATIONS; CORRELATION COEFFICIENT; LIMIT OF QUANTIFICATIONS; MULTI-TARGETS; O-DESMETHYL VENLAFAXINE; REGIONAL PRESCRIPTION DATA; SPE-HPLC-MS;

EXTRACTION;

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIARRHYTHMIC AGENT; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIFUNGAL AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DRUG; DRUG ANALYSIS; DRUG METABOLITE; NARCOTIC ANALGESIC AGENT; NEUROLEPTIC AGENT; SEWAGE; VASODILATOR AGENT; WATER POLLUTANT;

ANALYSIS; ARTICLE; CALIBRATION; CHEMISTRY; CHROMATOGRAPHY; CITY; CONTROLLED STUDY; DILUTION; DRUG DETERMINATION; EFFLUENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; MEASUREMENT ACCURACY; METABOLITE; PRESCRIPTION; PRIORITY JOURNAL; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SEWAGE; SOLID PHASE EXTRACTION; STANDARD; STATISTICAL MODEL; TANDEM MASS SPECTROMETRY; URBAN AREA; URINE; WASTE WATER; WATER POLLUTANT; WATER SAMPLING;

ANALYSIS; CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITIES; LINEAR MODELS; METHODS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEWAGE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; WATER POLLUTANTS, CHEMICAL;

EID: 84964211600     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2015.03.008     Document Type: Article

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