메뉴 건너뛰기




Volumn 21, Issue 18, 2014, Pages 10830-10839

Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment

Author keywords

Ecotoxicity; Elimination; Mixture toxicity; Monitoring; Pharmaceuticals; Risk assessment

Indexed keywords

ANTHROPOGENIC SOURCE; AQUATIC ENVIRONMENT; BIOMONITORING; DRUG; EFFLUENT; RISK ASSESSMENT; TOXICITY; WASTE TREATMENT; WASTEWATER;

EID: 84907861175     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-014-3060-z     Document Type: Article
Times cited : (98)

References (46)
  • 1
    • 84907860647 scopus 로고    scopus 로고
    • Monthly report of the monitoring station at Weil am Rhein
    • AUE (2011) Monthly report of the monitoring station at Weil am Rhein. Amt für Umwelt und Energie Basel-Stadt, http://www.aue.bs.ch/2011allweil.pdf (in German)
    • (2011) Amt für Umwelt und Energie Basel-Stadt
  • 2
    • 0029911418 scopus 로고    scopus 로고
    • Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucorinide and other related opiates
    • COI: 1:CAS:528:DyaK28XmtVWlur4%3D
    • Avdeef A, Barrett DA, Shaw PN, Knaggs RD, Davis SS (1996) Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucorinide and other related opiates. J Med Chem 39(22):4377–4381
    • (1996) J Med Chem , vol.39 , Issue.22 , pp. 4377-4381
    • Avdeef, A.1    Barrett, D.A.2    Shaw, P.N.3    Knaggs, R.D.4    Davis, S.S.5
  • 3
    • 84907860646 scopus 로고    scopus 로고
    • Set of monitoring data of environmental concentrations of pharmaceuticals. Vol 66/2011
    • Bergmann A, Fohrmann R, Weber F-A (2011) Set of monitoring data of environmental concentrations of pharmaceuticals. Vol 66/2011. Umweltbundesamt (in German)
    • (2011) Umweltbundesamt (in German)
    • Bergmann, A.1    Fohrmann, R.2    Weber, F.-A.3
  • 4
    • 84906095702 scopus 로고    scopus 로고
    • Biodegradability and transformation of human pharmaceutical active ingredients in environmentally relevant test systems
    • Berkner S, Thierbach C (2013) Biodegradability and transformation of human pharmaceutical active ingredients in environmentally relevant test systems. Environ Sci Pollut Res Int. doi:10.1007/s11356-013-1868-6
    • (2013) Environ Sci Pollut Res Int
    • Berkner, S.1    Thierbach, C.2
  • 5
    • 84907860645 scopus 로고    scopus 로고
    • Accessed 20 Dec 2013 (in German)
    • BUND (2012) www.bund-bawue.de. Accessed 20 Dec 2013 (in German)
    • (2012)
  • 6
    • 84907860644 scopus 로고    scopus 로고
    • Accessed 5 Jun 2013
    • ChemAxxon http://www.chemicalize.org/. Accessed 5 Jun 2013
  • 7
    • 0037447779 scopus 로고    scopus 로고
    • Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects
    • COI: 1:CAS:528:DC%2BD3sXis12lsb4%3D
    • Cleuvers M (2003) Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects. Toxicol Lett 142(3):185–194
    • (2003) Toxicol Lett , vol.142 , Issue.3 , pp. 185-194
    • Cleuvers, M.1
  • 8
    • 67349256707 scopus 로고    scopus 로고
    • Discharge of pharmaceutical products (PPs) through a conventional biological sewage treatment plant: MECs vs PECs?
    • COI: 1:CAS:528:DC%2BD1MXlsl2gt7k%3D
    • Coetsier CM, Spinelli S, Lin L, Roig B, Touraud E (2009) Discharge of pharmaceutical products (PPs) through a conventional biological sewage treatment plant: MECs vs PECs? Environ Int 35(5):787–792
    • (2009) Environ Int , vol.35 , Issue.5 , pp. 787-792
    • Coetsier, C.M.1    Spinelli, S.2    Lin, L.3    Roig, B.4    Touraud, E.5
  • 9
    • 84907860643 scopus 로고    scopus 로고
    • Accessed 5 Jun 2013
    • DrugBank http://www.drugbank.ca, DrugBank 3.0. Accessed 5 Jun 2013
    • DrugBank 3.0
  • 12
    • 78649652503 scopus 로고    scopus 로고
    • Environmental toxicology and risk assessment of pharmaceuticals from hospital wastewater
    • COI: 1:CAS:528:DC%2BC3cXhsFSqur3J
    • Escher BI, Baumgartner R, Koller M, Treyer K, Lienert J, McArdell CS (2011) Environmental toxicology and risk assessment of pharmaceuticals from hospital wastewater. Water Res 45(1):75–92
    • (2011) Water Res , vol.45 , Issue.1 , pp. 75-92
    • Escher, B.I.1    Baumgartner, R.2    Koller, M.3    Treyer, K.4    Lienert, J.5    McArdell, C.S.6
  • 13
    • 30644479441 scopus 로고    scopus 로고
    • Ecotoxicology of human pharmaceuticals
    • COI: 1:CAS:528:DC%2BD28Xjsl2qtQ%3D%3D
    • Fent K, Weston AA, Caminada D (2006) Ecotoxicology of human pharmaceuticals. Aquat Toxicol 76:122–159
    • (2006) Aquat Toxicol , vol.76 , pp. 122-159
    • Fent, K.1    Weston, A.A.2    Caminada, D.3
  • 14
    • 84866323362 scopus 로고    scopus 로고
    • Analysis of 100 pharmaceuticals and their degradates in water samples by liquid chromatography/quadrupole time-of-flight mass spectrometry
    • COI: 1:CAS:528:DC%2BC38XhtlKltL3E
    • Ferrer I, Thurman EM (2012) Analysis of 100 pharmaceuticals and their degradates in water samples by liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr A 1259:148–157
    • (2012) J Chromatogr A , vol.1259 , pp. 148-157
    • Ferrer, I.1    Thurman, E.M.2
  • 16
    • 84946031884 scopus 로고
    • Procedures for detecting outlying observations in samples
    • Grubbs FE (1969) Procedures for detecting outlying observations in samples. Technometrics 11(1):1–21
    • (1969) Technometrics , vol.11 , Issue.1 , pp. 1-21
    • Grubbs, F.E.1
  • 17
    • 0037052865 scopus 로고    scopus 로고
    • Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data
    • COI: 1:CAS:528:DC%2BD38Xjt1Wju7s%3D
    • Heberer T (2002) Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol Lett 131:5–17
    • (2002) Toxicol Lett , vol.131 , pp. 5-17
    • Heberer, T.1
  • 18
    • 77956164914 scopus 로고    scopus 로고
    • Structure-based interpretation of biotransformation pathways of amide-contaning compounds in sludge-seeded bioreactors
    • COI: 1:CAS:528:DC%2BC3cXpvVyltrw%3D
    • Helbling DE, Hollender J, Kohler H-PE, Fenner K (2010a) Structure-based interpretation of biotransformation pathways of amide-contaning compounds in sludge-seeded bioreactors. Environ Sci Technol 44:6628–6635
    • (2010) Environ Sci Technol , vol.44 , pp. 6628-6635
    • Helbling, D.E.1    Hollender, J.2    Kohler, H.-P.E.3    Fenner, K.4
  • 19
    • 77956157233 scopus 로고    scopus 로고
    • High-troughput identification of microbial transformation products of organic micropollutants
    • COI: 1:CAS:528:DC%2BC3cXptlygu7s%3D
    • Helbling DE, Hollender J, Kohler H-PE, Singer H, Fenner K (2010b) High-troughput identification of microbial transformation products of organic micropollutants. Environ Sci Technol 44:6621–6627
    • (2010) Environ Sci Technol , vol.44 , pp. 6621-6627
    • Helbling, D.E.1    Hollender, J.2    Kohler, H.-P.E.3    Singer, H.4    Fenner, K.5
  • 20
    • 31944449816 scopus 로고    scopus 로고
    • Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments
    • COI: 1:CAS:528:DC%2BD28Xht1ynsr4%3D
    • Hernando MD, Mezcua M, Fernández-Alba AR, Barceló D (2006) Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta 69:334–342
    • (2006) Talanta , vol.69 , pp. 334-342
    • Hernando, M.D.1    Mezcua, M.2    Fernández-Alba, A.R.3    Barceló, D.4
  • 21
    • 84907860641 scopus 로고    scopus 로고
    • Aliskiren / Valsartan, Global Pharma Environment
    • Hoeger B (2008) Novartis environmental assessment: Aliskiren / Valsartan. Global Pharma Environment. http://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/022217s000ea.pdf
    • (2008) Novartis environmental assessment
    • Hoeger, B.1
  • 22
    • 70450221098 scopus 로고    scopus 로고
    • Elimination of organic micropollutants in a municipal wastewater treatment plant upgraded with a full-scale post-ozonation followed by sand filtration
    • COI: 1:CAS:528:DC%2BD1MXpvV2gtrw%3D
    • Hollender J, Zimmermann SG, Koepke S, Krauss M, McArdell CS, Ort C, Singer H, von Gunten U, Siegrist H (2009) Elimination of organic micropollutants in a municipal wastewater treatment plant upgraded with a full-scale post-ozonation followed by sand filtration. Environ Sci Technol 43:7862–7869
    • (2009) Environ Sci Technol , vol.43 , pp. 7862-7869
    • Hollender, J.1    Zimmermann, S.G.2    Koepke, S.3    Krauss, M.4    McArdell, C.S.5    Ort, C.6    Singer, H.7    von Gunten, U.8    Siegrist, H.9
  • 24
    • 23744512414 scopus 로고    scopus 로고
    • Removal of pharmaceuticals and fragrances in biological wastewater treatment
    • COI: 1:CAS:528:DC%2BD2MXntlShsLc%3D
    • Joss A, Keller E, Alder AC, Gobel A, McArdell CS, Ternes T, Siegrist H (2005) Removal of pharmaceuticals and fragrances in biological wastewater treatment. Water Res 39(14):3139–3152
    • (2005) Water Res , vol.39 , Issue.14 , pp. 3139-3152
    • Joss, A.1    Keller, E.2    Alder, A.C.3    Gobel, A.4    McArdell, C.S.5    Ternes, T.6    Siegrist, H.7
  • 25
    • 53649084556 scopus 로고    scopus 로고
    • The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK
    • COI: 1:CAS:528:DC%2BD1cXnsFagu74%3D
    • Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ (2008) The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water Res 42(13):3498–3518
    • (2008) Water Res , vol.42 , Issue.13 , pp. 3498-3518
    • Kasprzyk-Hordern, B.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 26
    • 64149117531 scopus 로고    scopus 로고
    • Illicit drugs and pharmaceuticals in the environment—forensic applications of environmental data, part 2: pharmaceuticals as chemical markers of faecal water contamination
    • COI: 1:CAS:528:DC%2BD1MXksVCgsb0%3D
    • Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ (2009) Illicit drugs and pharmaceuticals in the environment—forensic applications of environmental data, part 2: pharmaceuticals as chemical markers of faecal water contamination. Environ Pollut 157(6):1778–1786
    • (2009) Environ Pollut , vol.157 , Issue.6 , pp. 1778-1786
    • Kasprzyk-Hordern, B.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 27
    • 78149246639 scopus 로고    scopus 로고
    • A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment
    • COI: 1:CAS:528:DC%2BC3cXhtlKku7nJ
    • Kern S, Baumgartner R, Helbling DE, Hollender J, Singer H, Loos MJ, Schwarzenbach RP, Fenner K (2010) A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment. J Environ Monitor 12:2100–2111
    • (2010) J Environ Monitor , vol.12 , pp. 2100-2111
    • Kern, S.1    Baumgartner, R.2    Helbling, D.E.3    Hollender, J.4    Singer, H.5    Loos, M.J.6    Schwarzenbach, R.P.7    Fenner, K.8
  • 28
    • 84856732714 scopus 로고    scopus 로고
    • Hospital wastewater treatment by membrane bioreactor: performance and efficiency for organic micropollutant elimination
    • COI: 1:CAS:528:DC%2BC38Xht1SntrY%3D
    • Kovalova L, Siegrist H, Singer H, Wittmer A, McArdell CS (2012) Hospital wastewater treatment by membrane bioreactor: performance and efficiency for organic micropollutant elimination. Environ Sci Technol 46:1536–1545
    • (2012) Environ Sci Technol , vol.46 , pp. 1536-1545
    • Kovalova, L.1    Siegrist, H.2    Singer, H.3    Wittmer, A.4    McArdell, C.S.5
  • 30
    • 67349114112 scopus 로고    scopus 로고
    • The presence of pharmaceuticals in the environment due to human use—present knowledge and future challenges
    • Kümmerer K (2009) The presence of pharmaceuticals in the environment due to human use—present knowledge and future challenges. J Environ Manag 90:2354–2366
    • (2009) J Environ Manag , vol.90 , pp. 2354-2366
    • Kümmerer, K.1
  • 31
    • 78049278862 scopus 로고    scopus 로고
    • Pharmaceuticals in the environment
    • Kümmerer K (2010) Pharmaceuticals in the environment. Annu Rev Environ Resour 35:57–75
    • (2010) Annu Rev Environ Resour , vol.35 , pp. 57-75
    • Kümmerer, K.1
  • 32
    • 34548354864 scopus 로고    scopus 로고
    • Effluent from drug manufactures contains extremely high levels of pharmaceuticals
    • COI: 1:CAS:528:DC%2BD2sXpslOqurs%3D
    • Larsson DGJ, de Pedro C, Paxeus N (2007) Effluent from drug manufactures contains extremely high levels of pharmaceuticals. J Hazard Mater 148:751–755
    • (2007) J Hazard Mater , vol.148 , pp. 751-755
    • Larsson, D.G.J.1    de Pedro, C.2    Paxeus, N.3
  • 33
    • 78249286535 scopus 로고    scopus 로고
    • Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system
    • COI: 1:CAS:528:DC%2BC3cXhsVagsbbN
    • Letzel M, Weiss K, Schüssler W, Sengl M (2010) Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system. Chemosphere 81:1416–1422
    • (2010) Chemosphere , vol.81 , pp. 1416-1422
    • Letzel, M.1    Weiss, K.2    Schüssler, W.3    Sengl, M.4
  • 35
    • 84902654530 scopus 로고    scopus 로고
    • Pharmaceuticals in drinking water
    • Jerome ON, (ed), Elsevier, Burlington
    • Maycock DS, Watts CD (2011) Pharmaceuticals in drinking water. In: Jerome ON (ed) Encyclopedia of environmental health. Elsevier, Burlington, pp 472–484
    • (2011) Encyclopedia of environmental health , pp. 472-484
    • Maycock, D.S.1    Watts, C.D.2
  • 36
    • 63449128408 scopus 로고    scopus 로고
    • Fate of pharmaceuticals and personal care products in wastewater treatment plants—conception of a database and first results
    • Miège C, Choubert JM, Ribeiro L, Eusebe M, Coquery M (2009) Fate of pharmaceuticals and personal care products in wastewater treatment plants—conception of a database and first results. Environ Pollut 157(5):1721–1726
    • (2009) Environ Pollut , vol.157 , Issue.5 , pp. 1721-1726
    • Miège, C.1    Choubert, J.M.2    Ribeiro, L.3    Eusebe, M.4    Coquery, M.5
  • 37
    • 67349111417 scopus 로고    scopus 로고
    • Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water
    • COI: 1:CAS:528:DC%2BD1MXlsl2gt7c%3D
    • Mompelat S, Le Bot B, Thomas O (2009) Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environ Int 35:803–814
    • (2009) Environ Int , vol.35 , pp. 803-814
    • Mompelat, S.1    Le Bot, B.2    Thomas, O.3
  • 38
    • 33846889562 scopus 로고    scopus 로고
    • Occurrence patterns of pharmaceuticals in water and wastewater environments
    • COI: 1:CAS:528:DC%2BD2sXhsFWlsbc%3D
    • Nikolaou A, Meric S, Fatta D (2007) Occurrence patterns of pharmaceuticals in water and wastewater environments. Anal Bioanal Chem 387:1225–1234
    • (2007) Anal Bioanal Chem , vol.387 , pp. 1225-1234
    • Nikolaou, A.1    Meric, S.2    Fatta, D.3
  • 39
    • 84886087860 scopus 로고    scopus 로고
    • Occurrence and fate of the angiotensin II receptor antagonist transformation product valsartan acid in the water cycle—a comparative study with selected β-blockers and the persistent anthropogenic wastewater indicators carbamazepine and acesulfame
    • Nödler K, Hillebrand O, Idzik K, Strathmann M, Schiperski F, Zirlewagen J, Licha T (2013) Occurrence and fate of the angiotensin II receptor antagonist transformation product valsartan acid in the water cycle—a comparative study with selected β-blockers and the persistent anthropogenic wastewater indicators carbamazepine and acesulfame. Water Res 47(17):6650–6659
    • (2013) Water Res , vol.47 , Issue.17 , pp. 6650-6659
    • Nödler, K.1    Hillebrand, O.2    Idzik, K.3    Strathmann, M.4    Schiperski, F.5    Zirlewagen, J.6    Licha, T.7
  • 41
    • 33846863180 scopus 로고    scopus 로고
    • Phytotoxicity assessment of diclofenac and its phototransformation products
    • COI: 1:CAS:528:DC%2BD2sXhsFWls7w%3D
    • Schmitt-Jansen M, Bartels P, Adler N, Altenburger R (2007) Phytotoxicity assessment of diclofenac and its phototransformation products. Anal Bioanal Chem 387:1389–1396
    • (2007) Anal Bioanal Chem , vol.387 , pp. 1389-1396
    • Schmitt-Jansen, M.1    Bartels, P.2    Adler, N.3    Altenburger, R.4
  • 44
    • 0142122458 scopus 로고    scopus 로고
    • Assessing the ecotoxicity of pesticide transformation products
    • COI: 1:CAS:528:DC%2BD3sXms12kt7c%3D
    • Sinclair CJ, Boxall ABA (2003) Assessing the ecotoxicity of pesticide transformation products. Environ Sci Technol 37:4617–4625
    • (2003) Environ Sci Technol , vol.37 , pp. 4617-4625
    • Sinclair, C.J.1    Boxall, A.B.A.2
  • 45
    • 84907860570 scopus 로고    scopus 로고
    • Assessed 20 Dec 2013 (in German)
    • Statistisches Bundesamt (2012) www.destatis.de. Assessed 20 Dec 2013 (in German)
    • (2012)
  • 46
    • 33750624076 scopus 로고    scopus 로고
    • Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent
    • Yu JT, Bouwer EJ, Coelhan M (2006) Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent. Agric Water Manag 86:72–80
    • (2006) Agric Water Manag , vol.86 , pp. 72-80
    • Yu, J.T.1    Bouwer, E.J.2    Coelhan, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.