Pharmacokinetics of metoprolol during pregnancy and lactation

Journal of Clinical Pharmacology

Volumn 56, Issue 5, 2016, Pages 581-589

  Ryu, Rachel J ^a   Eyal, Sara ^b   Easterling, Thomas R ^a,c   Caritis, Steve N ^d   Venkataraman, Raman ^d,e   Hankins, Gary ^f   Rytting, Erik ^f   Thummel, Kenneth ^a   Kelly, Edward J ^a   Risler, Linda ^a   Phillips, Brian ^a   Honaker, Matthew T ^a   Shen, Danny D ^a   Hebert, Mary F ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

^f University of Texas Medical Branch School of Medicine   (United States)

Author keywords

breast milk; CYP2D6; hypertension; metoprolol; pharmacokinetics; pregnancy

Indexed keywords

ALPHA HYDROXYMETOPROLOL; METOPROLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOCHROME P450 2D6; DELAYED RELEASE FORMULATION;

ADULT; AREA UNDER THE CURVE; ARTICLE; BREAST MILK; CLINICAL ARTICLE; CONCENTRATION AT STEADY-STATE; CYP2D6 GENE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EXPOSURE; DRUG URINE LEVEL; FEMALE; FIRST TRIMESTER PREGNANCY; GENE; GENETIC VARIATION; GENOTYPE; HUMAN; LACTATION; PHARMACOKINETIC PARAMETERS; PREGNANCY; PUERPERIUM; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; BLOOD; CLINICAL TRIAL; DELAYED RELEASE FORMULATION; GENETICS; METABOLISM; PHARMACOKINETICS; URINE; YOUNG ADULT;

ADRENERGIC BETA-ANTAGONISTS; ADULT; CYTOCHROME P-450 CYP2D6; DELAYED-ACTION PREPARATIONS; FEMALE; GENOTYPE; HUMANS; LACTATION; METOPROLOL; MILK, HUMAN; POSTPARTUM PERIOD; PREGNANCY; YOUNG ADULT;

EID: 84964199962     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.631     Document Type: Article

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