Amniotic fluid rapid biomarkers are associated with intra-amniotic infection in preterm pregnancies regardless of the membrane status

Journal of Perinatology

Volumn 36, Issue 8, 2016, Pages 606-611

  Myntti, T ^a   Rahkonen, L ^a   Tikkanen, M ^a   Patari Sampo A ^a   Paavonen, J ^a   Stefanovic, V ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GLUCOSE; LACTATE DEHYDROGENASE;

ADULT; AMNIOCENTESIS; AMNION; AMNIONITIS; ARTICLE; CHORIOAMNIONITIS; CULTURE MEDIUM; DISEASE ASSOCIATION; FEMALE; GESTATIONAL AGE; HISTOPATHOLOGY; HUMAN; MEMBRANE RUPTURE; PLACENTA; PREMATURITY; PRETERM PRELABOR RUPTURE OF THE MEMBRANE; AMNION FLUID; CHEMISTRY; FINLAND; MICROBIOLOGY; PATHOLOGY; PREGNANCY; PREMATURE FETUS MEMBRANE RUPTURE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC;

ADULT; AMNIOCENTESIS; AMNIOTIC FLUID; BIOMARKERS; CHORIOAMNIONITIS; FEMALE; FETAL MEMBRANES, PREMATURE RUPTURE; FINLAND; GESTATIONAL AGE; GLUCOSE; HUMANS; L-LACTATE DEHYDROGENASE; PLACENTA; PREGNANCY; PROSPECTIVE STUDIES; ROC CURVE;

EID: 84964001438     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/jp.2016.59     Document Type: Article

References (36)

1. Wu HC, Shen CM, Wu YY, Yuh YS, Kua KE. Subclinical histologic chorioamnionitis and related clinical and laboratory parameters in preterm deliveries. Pediatr Neonatol 2009; 50: 217-221
2. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet 2008; 371: 75-84
3. Roescher AM, Timmer A, Erwich JJ, Bos AF. Placental pathology, perinatal death, neonatal outcome, and neurological development: a systematic review. PLoS One 2014; 9: e89419
4. Garcia-Munoz Rodrigo F, Galan Henriquez GM, Ospina CG. Morbidity and mortality among very-low-birth-weight infants born to mothers with clinical chorioamnionitis. Pediatr Neonatol 2014; 55: 381-386
5. Edwards RK. Chorioamnionitis and Labor. Obstet Gynecol Clin North Am 2005; 32: 287-296
6. Xie A, Zhang W, Chen M, Wang Y, Wang Y, Zhou Q et al. Related factors and adverse neonatal outcomes in women with preterm premature rupture of membranes complicated by histologic chorioamnionitis. Med Sci Monit 2015; 21: 390-395
7. Menon R, Taylor RN, Fortunato SJ. Chorioamnionitis-A complex pathophysiologic syndrome. Placenta 2010; 31: 113-120
8. Lahra MM, Jeffery HE. A fetal response to chorioamnionitis is associated with early survival after preterm birth. Am J Obstet Gynecol 2004; 190: 147-151
9. Vajrychova M, Kacerovsky M, Tambor V, Hornychova H, Lenco J. Microbial invasion and histological chorioamnionitis upregulate neutrophil-gelatinase associated lipocalin in preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med 2016; 29: 12-21
10. Dulay AT, Buhimschi IA, Zhao G, Bahtiyar MO, Thung SF, Cackovic M et al. Compartmentalization of acute phase reactants interleukin-6, C-reactive protein and procalcitonin as biomarkers of intra-Amniotic infection and chorioamnionitis. Cytokine 2015; 76: 236-243
11. Romero R, Jimenez C, Lohda AK, Nores J, Hanaoka S, Avila C et al. Amniotic fluid glucose concentration: a rapid and simple method for the detection of intraamniotic infection in preterm labor. Am J Obstet Gynecol 1990; 163: 968-974
12. Ford C, Genc MR. Optimized amniotic fluid analysis in patients suspected of intrauterine infection/inflammation. J Perinat Med 2011; 40: 33-37
13. Buhimschi CS, Bhandari V, Hamar BD, Bahtiyar MO, Zhao G, Sfakianaki AK et al. Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsis. PLoS Med 2007; 4: e18
14. Romero R, Miranda J, Chaiworapongsa T, Chaemsaithong P, Gotsch F, Dong Z et al. A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra-Amniotic infection in preterm labor with intact membranes. Am J Reprod Immunol 2014; 71: 330-358
15. Pettker CM, Buhimschi IA, Magloire LK, Sfakianaki AK, Hamar BD, Buhimschi CS. Value of placental microbial evaluation in diagnosing intra-Amniotic infection. Obstet Gynecol 2007; 109: 739-749
16. DiGiulio DB, Romero R, Kusanovic JP, Gomez R, Kim CJ, Seok KS et al. Prevalence and diversity of microbes in the amniotic fluid, the fetal inflammatory response, and pregnancy outcome in women with preterm pre-labor rupture of membranes. Am J Reprod Immunol 2010; 64: 38-57
17. Payne MS, Bayatibojakhi S. Exploring preterm birth as a polymicrobial disease: an overview of the uterine microbiome. Front Immunol 2014; 5: 595
18. Gervasi MT, Romero R, Bracalente G, Chaiworapongsa T, Erez O, Dong Z et al. Viral invasion of the amniotic cavity (VIAC) in the midtrimester of pregnancy. J Matern Fetal Neonatal Med 2012; 25: 2002-2013
19. Romero R, Miranda J, Chaiworapongsa T, Korzeniewski SJ, Chaemsaithong P, Gotsch F et al. Prevalence and clinical significance of sterile intra-Amniotic inflammation in patients with preterm labor and intact membranes. Am J Reprod Immunol 2014; 72: 458-474
20. Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol 2015; 213(4 Suppl): S29-S52
21. Hitti J, Tarczy-Hornoch P, Murphy J, Hillier SL, Aura J, Eschenbach DA. Amniotic fluid infection, cytokines, and adverse outcome among infants at 34 weeks gestation or less. Obstet Gynecol 2001; 98: 1080-1088
22. Porreco RP, Heyborne KD, Shapiro H. Amniocentesis in the management of preterm premature rupture of the membranes: a retrospective cohort analysis. J Matern Fetal Neonatal Med 2008; 21: 573-579
23. Maki Y, Furukawa S, Kodama Y, Sameshima H, Ikenoue T. Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation. Early Hum Dev 2015; 91: 333-337
24. Shinjo A, Otsuki K, Sawada M, Ota H, Tokunaka M, Oba T et al. Retrospective cohort study: a comparison of two different management strategies in patients with preterm premature rupture of membranes. Arch Gynecol Obstet 2012; 286: 337-345
25. Akolekar R, Beta J, Picciarelli G, Ogilvie C, D'Antonio F. Procedure-related risk of miscarriage following amniocentesis and chorionic villus sampling: a systematic review and meta-Analysis. Ultrasound Obstet Gynecol 2015; 45: 16-26
26. Yeast JD, Garite TJ, Dorchester W. The risks of amniocentesis in the management of premature rupture of the membranes. Am J Obstet Gynecol 1984; 149: 505-508
27. Lee SY, Park KH, Jeong EH, Oh KJ, Ryu A, Kim A. Intra-Amniotic infection/inflammation as a risk factor for subsequent ruptured membranes after clinically indicated amniocentesis in preterm labor. J Korean Med Sci 2013; 28: 1226-1232
28. Garry D, Figueroa R, Aguero-Rosenfeld M, Martinez E, Visintainer P, Tejani N. A comparison of rapid amniotic fluid markers in the prediction of microbial invasion of the uterine cavity and preterm delivery. Obstet Gynecol 1996; 175: 1336-1341
29. Buhimschi CS, Buhimschi IA, Abdel-Razeq S, Rosenberg VA, Thung SF, Zhao G et al. Proteomic biomarkers of intra-Amniotic inflammation: relationship with funisitis and early-onset sepsis in the premature neonate. Pediatr Res 2007; 61: 318-324
30. Dulay AT, Buhimschi CS, Zhao G, Oliver EA, Mbele A, Jing S et al. Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection. J Immunol 2009; 182: 7244-7253
31. Kidokoro K, Furuhashi M, Kuno N, Ishikawa K. Amniotic fluid neutrophil elastase and lactate dehydrogenase: association with histologic chorioamnionitis. Acta Obstet Gynecol Scand 2006; 85: 669-674
32. Gauthier DW, Meyer WJ, Bieniarz A. Correlation of amniotic fluid glucose concentration and intraamniotic infection in patients with preterm labor or premature rupture of membranes. Am J Obstet Gynecol 1991; 165: 1105-1110
33. Odibo AO, Rodis JF, Sanders MM, Borgida AF, Wilson M, Egan JF et al. Relationship of amniotic fluid markers of intra-Amniotic infection with histopathology in cases of preterm labor with intact membranes. J Perinatol 1999; 19: 407-412
34. Greig PC, Ernest JM, Teot L. Low amniotic fluid glucose levels are a specific but not a sensitive marker for subclinical intrauterine infections in patients in preterm labor with intact membranes. Am J Obstet Gynecol 1994; 171: 365-370 discussion 370-1
35. Romero R, Miranda J, Chaemsaithong P, Chaiworapongsa T, Kusanovic JP, Dong Z et al. Sterile and microbial-Associated intra-Amniotic inflammation in preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med 2015; 28: 1394-1409
36. Combs CA, Gravett M, Garite TJ, Hickok DE, Lapidus J, Porreco R et al. Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes. Am J Obstet Gynecol 2014; 210: 125.e1-125.e15