Targeting of CCL2-CCR2-Glycosaminoglycan Axis Using a CCL2 Decoy Protein Attenuates Metastasis through Inhibition of Tumor Cell Seeding

Neoplasia (United States)

Volumn 18, Issue 1, 2016, Pages 49-59

  Roblek, Marko ^a   Strutzmann, Elisabeth ^b   Zankl, Christina ^b   Adage, Tiziana ^c   Heikenwalder, Mathias ^d,e   Atlic, Aid ^f   Weis, Roland ^f   Kungl, Andreas ^b,c,g   Borsig, Lubor ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF GRAZ   (Austria)

^c ProtAffin Biotechnologie AG   (Austria)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f VTU Engineering GmbH   (Austria)

^g Antagonis Biotherapeutics   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; GLYCOSAMINOGLYCAN; HUMAN SERUM ALBUMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MUTANT PROTEIN; PROTEOGLYCAN; SYNDECAN 4; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOACCUMULATION; BLOOD VESSEL PERMEABILITY; CANCER GROWTH; CHIMERA; CONTROLLED STUDY; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG BLOOD VESSEL; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TUMOR SEEDING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL MOTION; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HUMAN; LUNG NEOPLASMS; METABOLISM; METASTASIS; NEOPLASMS; PATHOLOGY; SECONDARY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION; GLYCOSAMINOGLYCANS; HUMANS; LUNG NEOPLASMS; MALE; MICE; NEOPLASM METASTASIS; NEOPLASMS; RECEPTORS, CCR2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SYNDECAN-4;

EID: 84963976727     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1016/j.neo.2015.11.013     Document Type: Article

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