Describing the prevalence of neural tube defects worldwide: A systematic literature review

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Zaganjor, Ibrahim ^a   Sekkarie, Ahlia ^a   Tsang, Becky L ^a   Williams, Jennifer ^a   Razzaghi, Hilda ^a,b   Mulinare, Joseph ^a,b   Sniezek, Joseph E ^a   Cannon, Michael J ^a   Rosenthal, Jorge ^a  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b Carter Consulting Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICA; ARTICLE; DISEASE SURVEILLANCE; EUROPE; HUMAN; INCOME; MORTALITY; NEURAL TUBE DEFECT; PACIFIC ISLANDS; PREVALENCE; SOUTHEAST ASIA; SOUTHERN EUROPE; SYSTEMATIC REVIEW; WESTERN HEMISPHERE; GLOBAL HEALTH; NEURAL TUBE DEFECTS;

GLOBAL HEALTH; HUMANS; NEURAL TUBE DEFECTS; PREVALENCE;

EID: 84963721909     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151586     Document Type: Article

References (133)

1. Christianson AL, Howson CP, Modell B. Global report on birth defects: the hidden toll of dying and disabled children. White Plains (NY): March of Dimes Birth Defects Foundation; 2006.
2. World Health Organization. Global health estimates (GHE)-Cause-specific mortality. 2015. Available: http://www.who.int/healthinfo/global burden disease/estimates/en/index1.html. Accessed 2015 Apr. 14.
3. World Health Organization. Global health estimates (GHE)-Disease burden. 2015. Available: http://www.who.int/healthinfo/global burden disease/estimates/en/index2.html. Accessed 2015 Apr. 14.
4. Blencowe H, Cousens S, Modell B, Lawn J. Folic acid to reduce neonatal mortality from neural tube disorders. International Journal of Epidemiology. 2010;39(Suppl 1):i110-i121. doi:10.1093/ije/dyq028 PMID: 20348114
5. Rudan I, Chan KY, Zhang JS, Theodoratou E, Feng XL, Salomon JA, etal. Causes of deaths in children younger than 5 years in China in 2008. The Lancet. 2010;375:1083-1089.
6. U. S. Centers for Disease Control and Prevention. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. Morbidity and Mortality Weekly Report. 1992;41:1-7.
7. Berry RJ, Baily L, Mulinare J, Bower C, Dary O. Fortification of flour with folic acid. Food and Nutrition Bulletin. 2010;31:22S-35S.
8. Crider KS, Bailey LB, Berry RJ. Folic acid food fortification-its history, effect, concerns, and future directions. Nutrients. 2011;3:370-384. doi:10.3390/nu3030370 PMID: 22254102
9. Berry RJ, Li Z, Erickson JD, Li S, Moore CA, Wang H, et al. Prevention of neural-tube defects with folic acid in China. New England Journal of Medicine. 1999;341:1485-1490. PMID: 10559448
10. U. S. Centers for Disease Control and Prevention. CDC Grand Rounds: additional opportunities to prevent neural tube defects with folic acid fortification. Morbidity and Mortality Weekly Report. 2010;59:980-984. PMID: 20703205
11. Sixty-Third World Health Assembly. Agenda item 11.7-Birth defects. 21 May 2010. Available: http://apps.who.int/gb/ebwha/pdf files/WHA63/A63 R17-en.pdf. Accessed 2015 Apr. 14.
12. Youngblood ME, Williamson R, Bell KN, Johnson Q, Kancherla V, Oakley GP. 2012 Update on global prevention of folic acid-preventable spina bifida and anencephaly. Birth Defects Research Part A: Clinical and Molecular Teratology. 2013;97:658-663.
13. Bhide P, Sagoo GS, Moorthie S, Burton H, Kar A. Systematic review of birth prevalence of neural tube defects in India. Birth Defects Research Part A: Clinical and Molecular Teratology. 2013;97:437-443.
14. Rosenthal J, Casas J, Taren D, Alverson CJ, Flores A, Frias J. Neural tube defects in Latin America and the impact of fortification: a literature review. Public Health Nutrition. 2014;17:537-550. doi:10. 1017/S1368980013000256 PMID: 23464652
15. Lo A, Polsek D, Sidhu S. Estimating the burden of neural tube defects in low-and middle-income countries. Journal of Global Health. 2014;4.
16. Moher D, Liberati A, Tetzlaff J, Altman DG. The PRISMA Group Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. PLoS Medicine. 2009;6.
17. World Health Organization. WHO regional offices. 2015. Available: http://www.who.int/about/regions/en/. Accessed 2015 Jul. 7.
18. World Bank. Country and lending groups. 2015. Available: http://data.worldbank.org/about/countryand-lending-groups. Accessed 2015 Jul. 7.
19. Houcher B, Akar N, Begag S, Egin Y. Neural tube defects in Algeria. INTECH Open Access Publisher; 2012.
20. Njamnshi AK, Djientcheu VDP, Lekoubou A, Guemse M, Obama MT, Mbu R, et al. Neural tube defects are rare among black Americans but not in sub-Saharan black Africans: the case of Yaounde-Cameroon. Journal of the Neurological Sciences. 2008;270:13-17. PMID: 18295800
21. Ahuka OL, Toko RM, Omanga FU, Tshimpanga BJ. Congenital malformations in the North-Eastern Democratic Republic of Congo during civil war. East African Medical Journal. 2006;8:95-99.
22. Anyebuno M, Amofa G, Peprah S, Affram A. Neural tube defects at Korle Bu Teaching Hospital, Accra, Ghana. East African Medical Journal. 1993;70:572-574. PMID: 8181439
23. Msamati BC, Igbigbi PS, Chisi JE. The incidence of cleft lip, cleft palate, hydrocephalus and spina bifida at Queen Elizabeth Central Hospital, Blantyre, Malawi. The Central African Journal of Medicine. 2000;46:292-296. PMID: 12002118
24. Ekanem TB, Okon DE, Akpantah AO, Mesembe OE, Eluwa MA, Ekong MB. Prevalence of congenital malformations in Cross River and Akwa Ibom states of Nigeria from 1980-2003. Congenital Anomalies. 2008;48:167-170. doi:10.1111/j.1741-4520.2008.00204.x PMID: 18983583
25. Airede KI. Neural tube defects in the middle belt of Nigeria. Journal of Tropical Pediatrics. 1992;38:27-30. PMID: 1573689
26. Sayed AR, Bourne D, Pattinson R, Nixon J, Henderson B. Decline in the prevalence of neural tube defects following folic acid fortification and its cost-benefit in South Africa. Birth Defects Research Part A: Clinical and Molecular Teratology. 2008;82:211-216.
27. Venter PA, Christianson AL, Hutamo CM, Makhura MP, Gericke GS. Congenital anomalies in rural black South African neonates-a silent epidemic?. South African Medical Journal. 1995;85:15-20. PMID: 7784908
28. Viljoen DL, Buccimazza S, Dunne T, Molteno C. The prevalence and prevention of neural tube defects in Cape Town. South African Medical Journal. 1995;85:630-632. PMID: 7482075
29. Kinasha AD, Manji K. The incidence and pattern of neural tube defects in Dares Salaam, Tanzania. European Journal of Pediatric Surgery. Supplement:, 2002; S38-S39.
30. Mohammed YA, Shawky RM, Soliman AA, Ahmed MM. Chromosomal study in newborn infants with congenital anomalies in Assiut University hospital: Cross-sectional study. Egyptian Journal of Medical Human Genetics. 2011;12:79-90.
31. Ebrahimi S, Ashkani S, Bagheri F. Prevalence of neural tube defects in Yasuj, Southwest Iran. Shiraz E-Medical Journal. 2013;14:1-9.
32. Behrooz AG, Gorjizadeh MH. Prevalence and Correlates of Neural Tube Defect in South West Iran. Sultan Qaboos University Medical Journal. 2007;7:31-34. PMID: 21654942
33. Abdollahi Z, Elmadfa I, Djazayery A, Golalipour MJ, Sadighi J, Salehi F, etal. Efficacy of flour fortification with folic acid in women of childbearing age in Iran. Annals of Nutrition and Metabolism. 2011;58:188-196. doi:10.1159/000329726 PMID: 21757892
34. Delshad S, Tabar AK, Samae H, Mollaean M, Nasiri SJ, Jazayeri SM, etal. The incidence of selected congenital malformations during atwo-year period in Tehran, Iran. Tropical Doctor. 2009;39; 156-158. doi:10.1258/td.2008.070434 PMID: 19535752
35. Afshar M, Golalipour MJ, Farhud D. Epidemiologic aspects of neural tube defects in South East Iran. Neurosciences. 2006;11:289-292. PMID: 22266439
36. Rad IA, Farrokh-Islamlou HR, Khoshkalam M. Neural tube defects prevalence in a hospital-based study in Urmia. Iranian Journal of Child Neurology. 2008;2:19-23.
37. Farhud DD, Hadavi V, Sadighi H. Epidemiology of neural tube defects in the world and Iran. Iranian journal of Public Health. 2000;29:83-90.
38. International Clearinghouse for Birth Defects Surveillance and Research. Annual report 2011 with data for 2009. Rome, Italy: The Centre of the International Clearinghouse for Birth Defects Surveillance and Research. 2011.
39. Al-Ani ZR, Al-Haj S, Al-Ani MM, Al-Dulaimy KM, Al-Maraie AK, Al-Ubaida BK. Incidence, types, geographical distribution, and risk factors of congenital anomalies in Al-Ramadi Maternity and Children's Teaching Hospital, Western Iraq. Saudi Medical Journal. 2012;33:979-989. PMID: 22964810
40. Al-Sadoon I, Hassan GG, Yacoub A. Depleted Uranium and health of people in Basrah: Epidemiological evidence: Incidence and pattern of congenital anomalies among birth in Basrah during the period 1990-1998. Medical Journal of Basrah University: 1999;17:27-33.
41. Amarin ZO, Obeidat AZ. Effect of folic acid fortification on the incidence of neural tube defects. Paediatricand Perinatal Epidemiology. 2010;24; 349-351. doi:10.1111/j.1365-3016.2010.01123.x PMID: 20618724
42. Aqrabawi HE. Incidence of neural tube defects among neonates at King Hussein Medical Centre, Jordan. Eastern Mediterranean Health Journal. 2005;11:819-823. PMID: 16700398
43. Masri AT. Neural tube defects in Jordan: A hospital based study. Journal of Pediatric Neurology. 2006;4:245-249.
44. Daoud AS, Al-Kaysi F, El-Shanti H, Batieha A, Obeidat A, Al-Sheyyab M. Neural tube defects in northern Jordan. Saudi Medical Journal. 1996;17:78-81.
45. Madi SA, Al-Naggar RL, Al-Awadi SA, Bastaki LA. Profile of major congenital malformations in neonates in Al-Jahra region of Kuwait. Eastern Mediterranean Health Journal. 2005;11:700-706. PMID: 16700386
46. Singh R, Al-Sudani O. Major congenital anomalies at birth in Benghazi, Libyan Arab Jamahiriya, 1995. Eastern Mediterranean Health Journal. 2000;6:65-75. PMID: 11370343
47. Alasfoor D, El Sayed MK. Fortification of Flour and Outcomes: Oman's Perspective-Contextual Considerations and Outcome. In: Handbookof Food Fortification and Health 2013 (pp. 321-334). Springer New York.
48. Khattak ST, Khan M, Naheed T, Khattak I, Ismail M. Prevalence and management of anencephaly at Saidu Teaching Hospital, Swat. Journal of Ayub Medical College, Abbottabad. 2009;22:61-63.
49. Qazi G. Relationship of selected prenatal factors to pregnancy outcome and congenital anomalies. Journal of Ayub Medical College, Abbottabad. 2010;22:41-45. PMID: 22455258
50. Perveen F, Tyyab S. Frequency and pattern of distribution of congenital anomalies in the newborn and associated maternal riskfactors. Journal of the College of Physicians and Surgeons-Pakistan. 2007;17:340-343. PMID: 17623582
51. Najmi RS. Riskfactors, clinical presentation and perinatal outcome of congenital malformations in a hospital based study. Journal of the College of Physicians and Surgeons-Pakistan. 1998;8:265-269.
52. Jooma R. Preventing neural tube defects by folic acid fortification of flour. The Journal of the Pakistan Medical Association. 2004;54:540-541. PMID: 15623176
53. Bener A, Kurdi B, Hoffmann GF, Caksen H, Teebi A. The pattern of neural tube defects in a highly endogamous society: A 25-year incidence trends. Journal of Pediatric Neurology. 2012;10:193-198.
54. Al-Jama F. Congenital malformations in newborns in a teaching hospital in eastern Saudi Arabia. Journal of Obstetrics & Gynecology. 2001;21:595-598.
55. Asindi A, Al-Shehri A. Neural tube defects in the Asir region of Saudi Arabia. Annals of Saudi Medicine. 2001;21:26-29. PMID: 17264584
56. Safdar OY, Al-Dabbagh AA, Abu Elieneen WA, Kari JA. Decline in the incidence of neural tube defects after the national fortification of flour (1997-2005). Saudi Medical Journal. 2007;28:1227-1229. PMID: 17676207
57. Murshid WR. Spina bifida in Saudi Arabia: is consanguinity among the parents a risk factor?. Pediatric Neurosurgery. 2000;32:10-12. PMID: 10765132
58. Hakami WS, Majeed-Saidan MA. The incidence and spectrum of central nervous system malformations in newborns over a decade (2001-2010) in the Central Region of Saudi Arabia. Saudi Medical Journal. 2011;32:1137-1142. PMID: 22057601
59. Elsheikh GEA, Ibrahim SA. Neural tube defects in Omdurman Maternity Hospital, Sudan. Khatoum Medical Journal. 2009;2:185-190.
60. Al Hosani H, Salah M, Abu-Zeid H, Farag HM, Saade D. The national congenital anomalies register in the United Arab Emirates. East Mediterranean Health Journal. 2005;11:690-699.
61. European Surveillance of Congenital Anomalies (EUROCAT). Prevalence Tables; 2012. Available: http://www.eurocat-network.eu/accessprevalencedata/prevalencetables.
62. Kovacheva K, Simeonova M, Velkova A. Trends and causes of congenital anomalies in the Pleven region, Bulgaria. Balkan Journal of Medical Genetics. 2009;12:37-43.
63. Pasternak B, Svanström H, Mølgaard-Nielsen D, Melbye M, Hviid A. Metoclopramide in pregnancy and risk of major congenital malformations and fetal death. The Journal of the American Medical Association. 2013;310:1601-1611. doi:10.1001/jama.2013.278343 PMID: 24129464
64. Stoll C, Dott B, Alembik Y, Roth MP. Associated malformations among infants with neural tube defects. American Journal of Medical Genetics Part A. 2011;155:565-568.
65. Klusmann A. Heinrich B, StöplerH, Gärtner J, MayatepekE, Kries R. A decreasing rate of neural tube defects following the recommendations for periconceptional folic acid supplementation. Acta Paediatrica. 2005;94:1538-1542. PMID: 16303691
66. McDonnell R, Delany V, Mahony MT, Mullaney C, Lee B, Turner MJ. Neural tube defects in the Republic of Ireland in 2009-11. Journal of Public Health. 2014;1-7.
67. Zlotogora J, Amitai Y, Leventhal A. Surveillance of neural tube defects in Israel: the effect of the recommendation for periconceptional folic acid. Israel Medical Association Journal. 2006;8:601-604. PMID: 17058407
68. Petrova JG, Vaktskjold A. The incidence of neural tube defects in Norway and the Arkhangelskaja Oblast in Russia and the association with maternal age. Acta Obstet Gynecol Scand. 2009;88:667-672. doi:10.1080/00016340902898008 PMID: 19353336
69. Poretti A, Anheier T, Zimmermann R, Boltshausei E. Neural tube defects in Switzerland from 2001 to 2007: are periconceptual folic acid recommendations being followed?. Swiss Medical Weekly. 2008;138:608-613. PMID: 18941947
70. Onrat ST, Seyman H, Konuk M. Incidence of neural tube defects in Afyonkarahisar, Western Turkey. Genetics and Molecular Research. 2009;8:154-161. PMID: 19283682
71. Mandiracioǧlu A, Ulman I, Lüleci E, Ulman C. The incidence and risk factors of neural tube defects in izmir, Turkey: A nested case-control study. The Turkish Journal of Pediatrics. 2004;46:214-220. PMID: 15503473
72. Tuncbilek E, Boduroǧlu K, Alikasifoǧlu M. Neural tube defects in Turkey: prevalence, distribution and riskfactors. TheTurkish Journal of Pediatrics. 1998;41:299-305.
73. Himmetoglu O, Tiras MB, Gursoy R, Karabacak O, Sahin I, Onan A. The incidence of congenital malformations in a Turkish population. International Journal of Gynecology & Obstetrics. 1996;55:117-121.
74. Groisman B, Bidondo MP, Barbero P, Gili JA, Liascovich R. RENAC: Registro Nacional de Anomalías Congénitas de Argentina. ArchivosArgentinosde Pediatría. 2013;111:484-494. PMID: 24196761
75. López-Camelo JS, Castilla EE, Orioli IM. Folic acid flour fortification: impact on the frequencies of 52 congenital anomaly types in three South American countries. American Journal of Medical Genetics Part A. 2010;152:2444-2458.
76. Orioli IM, Lima do Nascimento R, López-Camelo JS, Castilla EE. Effects of folic acid fortification on spina bifida prevalence in Brazil. Birth Defects Research Part A: Clinical and Molecular Teratology. 2011;91:831-835.
77. Nazer J, Cifuentes L. Resultados del Programa de Prevención de Defectos de Tubo Neural en Chile mediante lafortificación de la harinacon ácido fólico: Período 2001-2010. Revista Médica de Chile. 2013;141:751-757. doi:10.4067/S0034-98872013000600009
78. Pachajoa H, Ariza Y, Isaza C, Méndez F. Defectos congénitos mayoresen un hospital detercernivel en Cali, Colombia. Revista de Salud Pública. 2011;13:152-162.
79. Zarante I, Franco L, López C, Fernández N. Frecuencia de malformaciones congénitas: evaluación y pronóstico de 52.744 nacimientos en tres ciudades colombianas. Biomédica. 2010;30:65-71.
80. Ostos H, Astaiza G, Garcia F, Bautista M, Rojas F, Bermúdez A. Disminución de laincidenciade defectos de cierre del tubo neural en el Hospital Universitario de Neiva: posible efecto de la promoción del consumo de ácido fólico. Biomédica. 2000;20:18-24.
81. de la Paz Barboza-Argüello M, Umaña-Solís LM, Azofeifa A, Valencia D, Flores AL, Rodríguez-Aguilar S, etal. Neural Tube Defects in Costa Rica, 1987-2012: origins and Development of Birth Defect Surveillance and Folic Acid Fortification. Maternal and child Health Journal. 2015;19:583-590. doi:10.1007/s10995-014-1542-8 PMID: 24952876
82. González-Andrade F, López-Pulles R. Congenital malformations in Ecuadorian children: urgent need to create a National Registry of Birth Defects. The Application of Clinical Genetics. 2010;3:29-39. PMID: 23776361
83. Acevedo CR, Anzueto ER, Mendez AG, Ramirez FM. Prevalencia de anomalías congénitas mayores externas, en recién nacidos atendidos en hospitales nacionalesy regionalesde Guatemala 2001-2003. Undergraduate. Thesis, School of Medicine, Universidad de San Carlos de Guatemala. 2004.
84. Hernández R, Alvarenga R. Frecuencia de malformaciones congenitas externas en recién nacidos de la Unidad Materno Inantil del Hospital Escuela. Factores de Riesgo. Rev Med Post INAH. 2001;6:148-153.
85. Hernandez-Herrera RJ, Alcala-Galvan LG, Flores-Santos R. Prevalencia de defectos del tubo neural en 248 352 nacimientos consecutivos. Revista Medica del Instituto Mexicano Seguro Social. 2008;46:201-204.
86. Alfaro N, de Jesús Pérez J, Figueroa I, González Y. Malformaciones congénitas externas en la zona metropolitana de Guadalajara. 10 años de estudio. Investigación en Salud, 2004;6:180-187.
87. Navarrete Hernández E, Canún Serrano S, Reyes Pablo AE, del Carmen Sierra Romero M, Valdés Hernández J. Prevalencia de malformaciones congénitas registradas en el certificado de nacimiento y de muerte fetal: México, 2009-2010. Boletín médico del Hospital Infantil de México. 2013;70:499-505.
88. Sanabria Rojas HA, Tarqui-Mamani CB, Arias Pachas J, Lam Figueroa NM. Impacto de la fortificación de laharinadetrigocon ácido fólico en los defectos del tubo neural, en Lima, Perú. In Analesde la Facultad de Medicina. 2013;74:175-180.
89. Castilla EE, Orioli IM, Lopez-Camelo JS, da Graça Dutra M, Nazer-Herrera J. Preliminary data on changes in neural tube defect prevalence rates after folic acid fortification in South America. American Journal of Medical Genetics Part A. 2003;123:123-128.
90. Canfield MA, Mai CT, Wang P, O'Halloran A, Marengo LK, Olney RS, etal. The association between race/ethnicity and major birth defects in the United States, 1999-2007. American Journal of Public Health. 2014; e1-e10.
91. Dey AC, Shahidullah M, Mannan MA, Noor MK, Saha L, Rahman SA. Maternal and neonatal serum zinc level and its relationship with neural tube defects. Journal of Health, Population, and Nutrition. 2010;28:343-350. PMID: 20824977
92. Sarkar S, Patra C, Dasgupta MK, Nayek K, Karmakar PR. Prevalence of congenital anomalies in neonates and associated risk factors in a tertiary care hospital in eastern India. Journal of Clinical Neonatology. 2013;2:131-134. doi:10.4103/2249-4847.119998 PMID: 24251257
93. Sood M, Agarwal N, Verma S, Bhargava SK. Neural tubal defects in an east Delhi hospital. The Indian Journal of Pediatrics. 1991;58:363-365. PMID: 1937649
94. Sharma AK, Upreti M, Kamboj M, Mehra P, Das K, Misra A, etal. Incidence of neural tube defects at Lucknow over a 10 year period from 1982-1991. Indian Journal of Medical Research. 1994;99:223-226. PMID: 7927580
95. Mahadevan B, Bhat BV. Neural tube defects in Pondicherry. The Indian Journal of Pediatrics. 2005;72:557-559. PMID: 16077237
96. Duttachoudhury A, Pal SK. Congenital abnormalities in Durgapur Steel Plant Hospital with special reference to neural tube defect. Journal of the Indian Medical Association. 1997;95:135-141. PMID: 9357258
97. Ponne S, Lakshmi UK. Incidence of neural tube defects in Erode town. The Indian Journal of Nutrition and Dietetics. 2006;43:272-281.
98. Grover N. Congenital malformations in Shimla. The Indian Journal of Pediatrics. 2000;6:249-251.
99. Taksande A, Vilhekar K, Chaturvedi P, Jain M. Congenital malformations at birth in Central India: A rural medical college hospital based data. Indian Journal of Human Genetics. 2010;16:159-163. doi:10.4103/0971-6866.73412 PMID: 21206705
100. Malla BK. One year review study of congenital anatomical malformation at birth in Maternity Hospital (Prasutigriha), Thapathali, Kathmandu. Kathmandu University Medical Journal. 2007;5:557-560.
101. Jaruratanasirikul S, Kor-anantakul O, Limpitikul W, Dissaneevate P, Khunnarakpong N, Sattapanyo A. Prevalence of neural tube defect in southern Thailand: a population-based survey during 2009-2012. Child's Nervous System. 2014;30:1269-1275. doi:10.1007/s00381-014-2410-y PMID: 24740441
102. Kitisomprayoonkul N, Tongsong T. Neural tube defects: a different pattern in northern Thai population. Journal of the Medical Association of Thailand. 2001;84:483-488. PMID: 11460957
103. Wasant P, Sathienkijkanchai A. Neural tube defects at Siriraj Hospital, Bangkok, Thailand-10 years review (1990-1999). Journal of the Medical Association of Thailand. 2005;88; S92-S99.
104. Flood L, Scheil W, Nguyen AM, Sage L, Scott J. An increase in neural tube defect notifications, South Australia, 2009-2010. Western Pacific Surveillance and Response Journal. 2013;4:30-39. doi:10. 5365/WPSAR.2012.3.3.006 PMID: 24015369
105. Macaldowie A, Hilder L. Neural tube defects in Australia: prevalence before mandatory folic acid fortification. 2011. Canberra, Australia: Australian Institute of Health and Welfare.
106. Fan L, Gong T, Cao X, Du Y. Epidemiologic characteristics of birth defects in the Hainan Province from 2000 to 2010, China. Birth Defects Research Part A: Clinical and Molecular Teratology. 2013;97:750-754.
107. Yang M, Zhang S, Du Y. Epidemiology characteristics of birth defects in Shenzhen city during 2003 to 2009, China. The Journal of Maternal-Fetal & Neonatal Medicine. 2015;28:799-803.
108. Li X, Zhu J, Wang Y, Mu D, Dai L, Zhou G, etal. Geographic and urban-rural disparities in the total prevalence of neural tube defects and their subtypes during 2006-2008 in China: a study using the hospital-based birth defects surveillance system. BMC Public Health. 2013;13:161. doi:10.1186/1471-2458-13-161 PMID: 23433029
109. Zhang X, Li S, Wu S, Hao X, Guo S, Suzuki K, etal. Prevalence of birth defects and risk-factor analysis from a population-based survey in Inner Mongolia, China. BMC Pediatrics. 2012;12:125. doi:10. 1186/1471-2431-12-125 PMID: 22900612
110. Dai L, Zhu J, Liang J, Wang YP, Wang H, Mao M. Birth defects surveillance in China. World Journal of Pediatrics. 2011;7:302-310. doi:10.1007/s12519-011-0326-0 PMID: 22015723
111. Zhang XH, Qiu LQ, Huang JP. Risk of birth defects increased in multiple births. Birth Defects Research Part A: Clinical and Molecular Teratology. 2011;91:34-38.
112. Chen G, Pei LJ, Huang J, Song XM, Lin LM, Gu X, etal. Unusual patterns of neural tube defects in a high risk region of northern China. Biomedical and Environmental Sciences. 2009;22:340-344. doi:10.1016/S0895-3988 (09) 60065-9 PMID: 19950530
113. Li Y, Liu XH, Wang FY, Zhao XL, Zhang X, Zhang YP. Analysis of the birth defects among 61 272 live born infants in Beijing. Journal of Peking University, Health Sciences. 2009;41:414-417.
114. Liu J, Yang GZ, Zhou JL, Cao SP, Chau DH, Kung HF, etal. Prevalence of neural tube defects in economically and socially deprived area of China. Child's Nervous System. 2007;23:1119-1124. PMID: 17450368
115. Cheng N, Bai Y, Hu X, Pei H, Li Y, Zhang W, etal. A base-line survey on birth defects in Gansu province, West China. Annals of Tropical Paediatrics: International Child Health. 2003;23:25-29.
116. Chen BY, Hwang BF, Guo YL. Epidemiology of congenital anomalies in a population-based birth registry in Taiwan, 2002. Journal of the Formosan Medical Association. 2009;108:460-468. doi:10. 1016/S0929-6646 (09) 60093-0 PMID: 19515626
117. Imaizumi Y, Yamamura H, Nishikawa M, Matsuoka M, Moriyama I. The prevalence at birth of congenital malformations at a maternity hospital in Osaka City, 1948-1990. Japanese Journal of Human Genetics, 1991;36:275-287. PMID: 1753441
118. Seto T, Nakagawa H, Morikawa Y, Nishijo M, Miura K, Kadoshima Y. Trend of congenital anomalies over 20 years ascertained by population-based monitoring in Ishikawa Prefecture, Japan. Congenital Anomalies. 2003;43:286-293. PMID: 15041780
119. Kim MA, Yee NH, Choi JS, Choi JY, Seo K. Prevalence of birth defects in Korean livebirths, 2005-2006. Journal of Korean Medical Science. 2012;27:1233-1240. doi:10.3346/jkms.2012.27.10.1233 PMID: 23091323
120. Boo NY, Cheah IG, Thong MK. Neural tube defects in Malaysia: data from the Malaysian National Neonatal Registry. Journal of Tropical Pediatrics. 2013;59:338-342. doi:10.1093/tropej/fmt026 PMID: 23583959
121. Dryden R. Birth defects recognized in 10, 000 babies born consecutively in Port Moresby General Hospital, Papua New Guinea. Papua New Guinea Medical Journal. 1997;40:4-13. PMID: 10365565
122. Shi LM, Chia SE, Chan OY, Chew SK, Foong BH. Prevalence of birth defects and parental work in Singapore live births from 1994 to 1998: a population-based study. Occupational Medicine. 2002;52:325-331. PMID: 12361994
123. Hoang T, Nguyen PVN, Tran DA, Gillerot Y, Reding R, Robert A. External birth defects in southern Vietnam: a population-based study at the grassroots level of health care in Binh Thuan province. BMC Pediatrics. 2013;13:67. doi:10.1186/1471-2431-13-67 PMID: 23631673
124. Dudin A. Neural tube defect among Palestinians: a hospital-based study. Annals of Tropical Paediatrics. 1997;17:217-222. PMID: 9425376
125. World Health Organization. Countries. 2015. Available: http://www.who.int/countries/en/. Accessed 2015 Jul. 8.
126. Luquetti DV, Koifman RJ. Validity and reliability of the Brazilian birth defects certificate for reporting birth defects. Journal of Registry Management. 2010;37:112-120. PMID: 21462883
127. Bower C, Stanley FJ. Dietary folate as a risk for neural-tube defects: evidence from a case-control study in Western Australia. The Medical Journal of Australia. 1989;150:613-619. PMID: 2725375
128. Yan L, Zhao L, Long Y, Zou P, Ji G, Gu A, etal. Association of the maternal MTHFRc677T polymorphism with susceptibility to neural tube defects in offsprings: evidence from 25 case-control studies. PloSOne. 2012;7; e41689. doi:10.1371/journal.pone.0041689 PMID: 23056169
129. De Wals P, Tairou F, Van Allen MI, Uh SH, Lowry RB, Sibbald B, etal. Reduction in neural-tube defects after folic acid fortification in Canada. New England Journal of Medicine. 2007;357:135-142. PMID: 17625125
130. Borman B, Cryer C. Fallacies of international and national comparisons of disease occurrence in the epidemiology of neural tube defects. Teratology. 1990;42:405-412. PMID: 2256003
131. WHO/CDC/ICBDSR. Birth defects surveillance: a manual for programme managers. Geneva: World Health Organization; 2014.
132. WHO/CDC/ICBDSR. Birth defects surveillance: atlas of selected congenital anomalies. Geneva: World Health Organization; 2014.
133. U. S. Centers for Disease Control and Prevention. Folic acid: Birth Defects COUNT. 2014 Oct. 14. Atlanta. Available: http://www.cdc.gov/ncbddd/birthdefectscount/cdc.html. Accessed 2015 Apr. 14.