메뉴 건너뛰기




Volumn 21, Issue 3, 2016, Pages

Silver nanoparticles exhibit the dose-dependent anti-proliferative effect against human squamous carcinoma cells attenuated in the presence of berberine

Author keywords

Bax bcl 2 gene expression; Berberine; MTT assay; Oral carcinoma; RT QPCR; SCC 25cell cycle arrest; Silver nanoparticles

Indexed keywords

BERBERINE; METAL NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SILVER;

EID: 84963647517     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules21030365     Document Type: Article
Times cited : (62)

References (44)
  • 1
    • 42149129398 scopus 로고    scopus 로고
    • Head and neck cancer: Changing epidemiology, diagnosis, and treatment
    • [CrossRef] [PubMed]
    • Marur, S.; Forastiere, A.A. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin. Proc. 2008, 83, 489-501. [CrossRef] [PubMed]
    • (2008) Mayo Clin. Proc. , vol.83 , pp. 489-501
    • Marur, S.1    Forastiere, A.A.2
  • 5
    • 0032426999 scopus 로고    scopus 로고
    • Variation in survival of patients with head and neck cancer in Europe by the site of origin of the tumours
    • [CrossRef]
    • Berrino, F.; Gatta, G. Variation in survival of patients with head and neck cancer in Europe by the site of origin of the tumours. Eur. J. Cancer 1998, 34, 2154-2161. [CrossRef]
    • (1998) Eur. J. Cancer , vol.34 , pp. 2154-2161
    • Berrino, F.1    Gatta, G.2
  • 7
    • 80051536318 scopus 로고    scopus 로고
    • Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma
    • [CrossRef] [PubMed]
    • Besic Gyenge, E.; Darphin, X.; Wirth, A.; Pieles, U.; Walt, H.; Bredell, M.; Maake, C. Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma. J. Nanobiotechnol. 2011, 11, 32. [CrossRef] [PubMed]
    • (2011) J. Nanobiotechnol. , vol.11 , pp. 32
    • Besic Gyenge, E.1    Darphin, X.2    Wirth, A.3    Pieles, U.4    Walt, H.5    Bredell, M.6    Maake, C.7
  • 9
    • 33845346100 scopus 로고    scopus 로고
    • Nanoparticles: Health effects-pros and cons
    • [CrossRef] [PubMed]
    • Gwinn, M.R.; Vallyathan, V. Nanoparticles: Health Effects-Pros and Cons. Environ. Health Perspect. 2006, 114, 1818-1825. [CrossRef] [PubMed]
    • (2006) Environ. Health Perspect. , vol.114 , pp. 1818-1825
    • Gwinn, M.R.1    Vallyathan, V.2
  • 10
    • 34250210524 scopus 로고    scopus 로고
    • Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli
    • [CrossRef] [PubMed]
    • Shahverdi, A.R.; Fakhimi, A.; Shahverdi, H.R.; Minaian, S. Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomedicine 2007, 3, 168-171. [CrossRef] [PubMed]
    • (2007) Nanomedicine , vol.3 , pp. 168-171
    • Shahverdi, A.R.1    Fakhimi, A.2    Shahverdi, H.R.3    Minaian, S.4
  • 12
    • 33750096683 scopus 로고    scopus 로고
    • Silver in health care: Antimicrobial effects and safety in use
    • Lansdown, A.B. Silver in health care: antimicrobial effects and safety in use. Dermatology 2006, 33, 17-34.
    • (2006) Dermatology , vol.33 , pp. 17-34
    • Lansdown, A.B.1
  • 13
    • 84963702809 scopus 로고    scopus 로고
    • Toxicological investigation of nanoparticles: Effects on human cells. 13th Scientific Symposium of the Austrian Pharmacological Society (APHAR). Joint Meeting with the Austrian Society of Toxicology (ASTOX) and the Hungarian Society for Experimental and Clinical Pharmacology (MFT) Vienna, Austria. 2224 November 2007
    • (accessed on 14 March 2016)
    • Farmer, L.; Graff, A.; Szameit, S.; Valic, E.; Tuschl, H. Toxicological investigation of nanoparticles: Effects on human cells. 13th Scientific Symposium of the Austrian Pharmacological Society (APHAR). Joint Meeting with the Austrian Society of Toxicology (ASTOX) and the Hungarian Society for Experimental and Clinical Pharmacology (MFT) Vienna, Austria. 2224 November 2007. BMC Pharmacol. 2007, 7, A55. Available online: http://www.vitrocell.com/portals/0/news/publications/poster-nanoparticles-farmer.pdf (accessed on 14 March 2016).
    • (2007) BMC Pharmacol. , vol.7 , pp. A55
    • Farmer, L.1    Graff, A.2    Szameit, S.3    Valic, E.4    Tuschl, H.5
  • 14
    • 24644463185 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for squamous cell carcinoma of the oral tongue in young adults: A case series
    • [CrossRef] [PubMed]
    • Sturgis, E.M.; Moore, B.A.; Glisson, B.S.; Kies, M.S.; Shin, D.M.; Byers, R.M. Neoadjuvant chemotherapy for squamous cell carcinoma of the oral tongue in young adults: A case series. Head Neck 2005, 27, 748-756. [CrossRef] [PubMed]
    • (2005) Head Neck , vol.27 , pp. 748-756
    • Sturgis, E.M.1    Moore, B.A.2    Glisson, B.S.3    Kies, M.S.4    Shin, D.M.5    Byers, R.M.6
  • 15
    • 33846959148 scopus 로고    scopus 로고
    • Effect of colloidal silver against the cytotoxicity of hydrogen peroxide and naphthazarin on primary cultured cortical astrocytes
    • [CrossRef] [PubMed]
    • Kim, D.W.; Hong, G.H.; Lee, H.H.; Choi, S.H.; Chun, B.G.; Won, C.K.; Hwang, I.K.; Won, M.H. Effect of colloidal silver against the cytotoxicity of hydrogen peroxide and naphthazarin on primary cultured cortical astrocytes. Neuroscience 2007, 117, 387-400. [CrossRef] [PubMed]
    • (2007) Neuroscience , vol.117 , pp. 387-400
    • Kim, D.W.1    Hong, G.H.2    Lee, H.H.3    Choi, S.H.4    Chun, B.G.5    Won, C.K.6    Hwang, I.K.7    Won, M.H.8
  • 16
    • 27944489615 scopus 로고    scopus 로고
    • In vitro cytotoxicity of nanoparticles in mammalian germline stem cells
    • [CrossRef] [PubMed]
    • Braydich-Stolle, L.; Hussain, S.; Schlager, J.J.; Hofmann, M.C. In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells. Toxicol. Sci. 2005, 88, 412-419. [CrossRef] [PubMed]
    • (2005) Toxicol. Sci. , vol.88 , pp. 412-419
    • Braydich-Stolle, L.1    Hussain, S.2    Schlager, J.J.3    Hofmann, M.C.4
  • 17
    • 56249083197 scopus 로고    scopus 로고
    • DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells
    • [CrossRef] [PubMed]
    • Ahamed, M.; Karns, M.; Goodson, M.; Rowe, J.; Hussain, S.M.; Schlager, J.J.; Hong, Y. DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells. Toxicol. Appl. Pharmacol. 2008, 233, 404-410. [CrossRef] [PubMed]
    • (2008) Toxicol. Appl. Pharmacol. , vol.233 , pp. 404-410
    • Ahamed, M.1    Karns, M.2    Goodson, M.3    Rowe, J.4    Hussain, S.M.5    Schlager, J.J.6    Hong, Y.7
  • 18
    • 69449084368 scopus 로고    scopus 로고
    • PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes
    • [CrossRef] [PubMed]
    • Foldbjerg, R.; Olesen, P.; Hougaard, M.; Dang, D.A.; Hoffmann, H.J.; Autrup, H. PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes. Toxicol. Lett. 2009, 190, 156-162. [CrossRef] [PubMed]
    • (2009) Toxicol. Lett. , vol.190 , pp. 156-162
    • Foldbjerg, R.1    Olesen, P.2    Hougaard, M.3    Dang, D.A.4    Hoffmann, H.J.5    Autrup, H.6
  • 20
    • 71949097349 scopus 로고    scopus 로고
    • Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells
    • [PubMed]
    • Ho, Y.T.; Lu, C.C.; Yang, J.S.; Chiang, J.H.; Li, T.C.; Ip, S.W.; Hsia, T.C.; Liao, C.L.; Lin, J.G.; Wood, W.G.; et al. Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells. Anticancer Res. 2009, 29, 4063-4070. [PubMed]
    • (2009) Anticancer Res. , vol.29 , pp. 4063-4070
    • Ho, Y.T.1    Lu, C.C.2    Yang, J.S.3    Chiang, J.H.4    Li, T.C.5    Ip, S.W.6    Hsia, T.C.7    Liao, C.L.8    Lin, J.G.9    Wood, W.G.10
  • 21
    • 67349103384 scopus 로고    scopus 로고
    • Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9
    • [CrossRef] [PubMed]
    • Ho, Y.T.; Yang, J.S.; Li, T.C.; Lin, J.J.; Lin, J.G.; Lai, K.C.; Ma, C.Y.; Wood, W.G.; Chung, J.G. Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9. Cancer Lett. 2009, 279, 155-162. [CrossRef] [PubMed]
    • (2009) Cancer Lett. , vol.279 , pp. 155-162
    • Ho, Y.T.1    Yang, J.S.2    Li, T.C.3    Lin, J.J.4    Lin, J.G.5    Lai, K.C.6    Ma, C.Y.7    Wood, W.G.8    Chung, J.G.9
  • 22
    • 84943777828 scopus 로고    scopus 로고
    • Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells
    • [CrossRef] [PubMed]
    • Seo, Y.S.; Yim, M.J.; Kim, B.H.; Kang, K.R.; Lee, S.Y.; Oh, J.S.; You, J.S.; Kim, S.G.; Yu, S.J.; Lee, G.J.; et al. Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells. Oncol. Rep. 2015, 25, 3025-3034. [CrossRef] [PubMed]
    • (2015) Oncol. Rep. , vol.25 , pp. 3025-3034
    • Seo, Y.S.1    Yim, M.J.2    Kim, B.H.3    Kang, K.R.4    Lee, S.Y.5    Oh, J.S.6    You, J.S.7    Kim, S.G.8    Yu, S.J.9    Lee, G.J.10
  • 23
    • 84880903718 scopus 로고    scopus 로고
    • Cytotoxicity of biologically synthesized silver nanoparticles in MDA-MB-231 human breast cancer cells
    • [CrossRef] [PubMed]
    • Gurunathan, S.; Han, J.W.; Eppakayala, V.; Jeyaraj, M.; Kim, J.H. Cytotoxicity of biologically synthesized silver nanoparticles in MDA-MB-231 human breast cancer cells. Biomed. Res. Int. 2013, 2013, 535796. [CrossRef] [PubMed]
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 535796
    • Gurunathan, S.1    Han, J.W.2    Eppakayala, V.3    Jeyaraj, M.4    Kim, J.H.5
  • 25
    • 70449413628 scopus 로고    scopus 로고
    • Anti-proliferative activity of silver nanoparticles
    • [CrossRef] [PubMed]
    • AshaRani, P.V.; Prakash Hande, M.; Valiyaveettil, S. Anti-proliferative activity of silver nanoparticles. BMC Cell Biol. 2009, 10, 65. [CrossRef] [PubMed]
    • (2009) BMC Cell Biol. , vol.10 , pp. 65
    • AshaRani, P.V.1    Prakash Hande, M.2    Valiyaveettil, S.3
  • 26
    • 84896756827 scopus 로고    scopus 로고
    • The cellular uptake and cytotoxic effect of silver nanoparticles on chronic myeloid leukemia cells
    • [CrossRef] [PubMed]
    • Guo, D.; Zhao, Y.; Zhang, Y.; Wang, Q.; Huang, Z.; Ding, Q.; Guo, Z.; Zhou, X.; Zhu, L.; Gu, N. The cellular uptake and cytotoxic effect of silver nanoparticles on chronic myeloid leukemia cells. J. Biomed. Nanotechnol. 2014, 10, 669-678. [CrossRef] [PubMed]
    • (2014) J. Biomed. Nanotechnol. , vol.10 , pp. 669-678
    • Guo, D.1    Zhao, Y.2    Zhang, Y.3    Wang, Q.4    Huang, Z.5    Ding, Q.6    Guo, Z.7    Zhou, X.8    Zhu, L.9    Gu, N.10
  • 27
    • 84923284277 scopus 로고    scopus 로고
    • Silver nanoparticles biosynthesized using achillea biebersteinii flower extract: Apoptosis induction in MCF-7 cells via caspase activation and regulation of Bax and Bcl-2 gene expression
    • [CrossRef] [PubMed]
    • Baharara, J.; Namvar, F.; Ramezani, T.; Mousavi, M.; Mohamad, R. Silver Nanoparticles Biosynthesized Using Achillea biebersteinii Flower Extract: Apoptosis Induction in MCF-7 Cells via Caspase Activation and Regulation of Bax and Bcl-2 Gene Expression. Molecules 2015, 20, 2693-2706. [CrossRef] [PubMed]
    • (2015) Molecules , vol.20 , pp. 2693-2706
    • Baharara, J.1    Namvar, F.2    Ramezani, T.3    Mousavi, M.4    Mohamad, R.5
  • 28
    • 78549241716 scopus 로고    scopus 로고
    • P38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells
    • [CrossRef] [PubMed]
    • Eom, H.J.; Choi, J. p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells. Environ. Sci. Technol. 2010, 44, 8337-8342. [CrossRef] [PubMed]
    • (2010) Environ. Sci. Technol. , vol.44 , pp. 8337-8342
    • Eom, H.J.1    Choi, J.2
  • 30
    • 84947125894 scopus 로고    scopus 로고
    • A polysaccharide from the alkaline extract of Glycyrrhiza inflata induces apoptosis of human oral cancer SCC-25 cells via mitochondrial pathway
    • [CrossRef] [PubMed]
    • Zeng, G.; Shen, H.; Tang, G.; Cai, X.; Bi, L.; Sun, B.; Yang, Y.; Xun, W. A polysaccharide from the alkaline extract of Glycyrrhiza inflata induces apoptosis of human oral cancer SCC-25 cells via mitochondrial pathway. Tumour. Biol. 2015, 36, 6781-6788. [CrossRef] [PubMed]
    • (2015) Tumour. Biol. , vol.36 , pp. 6781-6788
    • Zeng, G.1    Shen, H.2    Tang, G.3    Cai, X.4    Bi, L.5    Sun, B.6    Yang, Y.7    Xun, W.8
  • 31
    • 4644251550 scopus 로고    scopus 로고
    • Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis
    • [CrossRef] [PubMed]
    • Andrews, G.A.; Xi, S.; Pomerantz, R.G.; Lin, C.J.; Gooding, W.E.; Wentzel, A.L.; Wu, L.; Sidransky, D.; Grandis, J.R. Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis. Head Neck 2004, 26, 870-877. [CrossRef] [PubMed]
    • (2004) Head Neck , vol.26 , pp. 870-877
    • Andrews, G.A.1    Xi, S.2    Pomerantz, R.G.3    Lin, C.J.4    Gooding, W.E.5    Wentzel, A.L.6    Wu, L.7    Sidransky, D.8    Grandis, J.R.9
  • 32
    • 84916624203 scopus 로고    scopus 로고
    • Biogenic metal nanoformulations induce Bax/Bcl2 and caspase mediated mitochondrial dysfunction in human breast cancer cells (MCF-7)
    • [CrossRef]
    • Jeyaraj, M.; Renganathan, A.; Sathishkumar, G.; Ganapathi, A.; Premkumar, K. Biogenic metal nanoformulations induce Bax/Bcl2 and caspase mediated mitochondrial dysfunction in human breast cancer cells (MCF-7). RSC Adv. 2015, 5, 2159-2166. [CrossRef]
    • (2015) RSC Adv. , vol.5 , pp. 2159-2166
    • Jeyaraj, M.1    Renganathan, A.2    Sathishkumar, G.3    Ganapathi, A.4    Premkumar, K.5
  • 33
    • 44749083229 scopus 로고    scopus 로고
    • Visual colorimetric detection of berberine hydrochloride with silver nanoparticles
    • [CrossRef] [PubMed]
    • Ling, J.; Sang, Y.; Huang, C.Z. Visual colorimetric detection of berberine hydrochloride with silver nanoparticles. J. Pharm. Biomed. Anal. 2008, 47, 860-864. [CrossRef] [PubMed]
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 860-864
    • Ling, J.1    Sang, Y.2    Huang, C.Z.3
  • 34
    • 84910661734 scopus 로고    scopus 로고
    • Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer
    • [CrossRef] [PubMed]
    • Jabbarzadeh Kaboli, P.; Rahmat, A.; Ismail, P.; Ling, K.H. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur. J. Pharmacol. 2014, 740, 584-595. [CrossRef] [PubMed]
    • (2014) Eur. J. Pharmacol. , vol.740 , pp. 584-595
    • Jabbarzadeh Kaboli, P.1    Rahmat, A.2    Ismail, P.3    Ling, K.H.4
  • 35
    • 84904489183 scopus 로고    scopus 로고
    • Hormesis effects of silver nanoparticles at non-cytotoxic doses to Human hepatoma cells
    • [CrossRef] [PubMed]
    • Jiao, Z.H.; Li, M.; Feng, Y.X.; Shi, J.C.; Zhang, J.; Shao, B. Hormesis Effects of Silver Nanoparticles at Non-Cytotoxic Doses to Human Hepatoma Cells. PLoS ONE 2014, 9, e102564. [CrossRef] [PubMed]
    • (2014) PLoS ONE , vol.9 , pp. e102564
    • Jiao, Z.H.1    Li, M.2    Feng, Y.X.3    Shi, J.C.4    Zhang, J.5    Shao, B.6
  • 36
    • 84872446537 scopus 로고    scopus 로고
    • Antiproliferative effect of silver nanoparticles synthesized using amla on Hep2 cell line
    • [CrossRef]
    • Rosarin, F.S.; Arulmozhi, V.; Nagarajan, S.; Mirunalini, S. Antiproliferative effect of silver nanoparticles synthesized using amla on Hep2 cell line. Asian Pac. J. Trop. Med. 2013, 6, 1-10. [CrossRef]
    • (2013) Asian Pac. J. Trop. Med. , vol.6 , pp. 1-10
    • Rosarin, F.S.1    Arulmozhi, V.2    Nagarajan, S.3    Mirunalini, S.4
  • 38
    • 33947360667 scopus 로고    scopus 로고
    • In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line
    • [CrossRef] [PubMed]
    • Chang, J.S.; Chang, K.L.; Hwang, D.F.; Kong, Z.L. In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line. Environ. Sci. Technol. 2007, 41, 2064-2068. [CrossRef] [PubMed]
    • (2007) Environ. Sci. Technol. , vol.41 , pp. 2064-2068
    • Chang, J.S.1    Chang, K.L.2    Hwang, D.F.3    Kong, Z.L.4
  • 39
    • 84936936565 scopus 로고    scopus 로고
    • Silver Nanoparticles-induced cytotoxicity requires ERK activation in human bladder carcinoma cells
    • [CrossRef] [PubMed]
    • Castiglioni, S.; Cazzaniga, A.; Perotta, C.; Maier, J.A. Silver Nanoparticles-induced cytotoxicity requires ERK activation in human bladder carcinoma cells. Toxicol. Lett. 2015, 273, 237-243. [CrossRef] [PubMed]
    • (2015) Toxicol. Lett. , vol.273 , pp. 237-243
    • Castiglioni, S.1    Cazzaniga, A.2    Perotta, C.3    Maier, J.A.4
  • 40
    • 73949087550 scopus 로고    scopus 로고
    • Effect of surface properties on nanoparticle-cell interactions
    • [CrossRef] [PubMed]
    • Verma, A.; Stellacci, F. Effect of surface properties on nanoparticle-cell interactions. Small 2010, 6, 12-21. [CrossRef] [PubMed]
    • (2010) Small , vol.6 , pp. 12-21
    • Verma, A.1    Stellacci, F.2
  • 41
    • 84901391283 scopus 로고    scopus 로고
    • Nanosilver particles in medical applications: Synthesis, performance, and toxicity
    • Ge, L.; Li, Q.; Wang, M.; Ouyang, J.; Li, X.; Xing, M.M. Nanosilver particles in medical applications: synthesis, performance, and toxicity. Int. J. Nanomed. 2014, 16, 2399-2407.
    • (2014) Int. J. Nanomed. , vol.16 , pp. 2399-2407
    • Ge, L.1    Li, Q.2    Wang, M.3    Ouyang, J.4    Li, X.5    Xing, M.M.6
  • 42
    • 84928087648 scopus 로고    scopus 로고
    • Short- and long-term effects of silver nanoparticles on human microvascular endothelial cells
    • [CrossRef] [PubMed]
    • Castiglioni, S.; Caspani, C.; Cazzaniga, A.; Maier, J.A. Short- and long-term effects of silver nanoparticles on human microvascular endothelial cells. World J. Biol. Chem. 2014, 5, 457-464. [CrossRef] [PubMed]
    • (2014) World J. Biol. Chem. , vol.5 , pp. 457-464
    • Castiglioni, S.1    Caspani, C.2    Cazzaniga, A.3    Maier, J.A.4
  • 43
    • 84963690835 scopus 로고    scopus 로고
    • Sigma-Aldrich. Silver, Dispersion. EC Number: 231-791-2. (accessed on 14 March)
    • Specification Sheet. Sigma-Aldrich. Silver, Dispersion. EC Number: 231-791-2. Available online: http://www.sigmaaldrich.com/catalog/product/aldrich/730785?lang=pl®ion=PL (accessed on 14 March 2016).
    • (2016) Specification Sheet
  • 44
    • 84963690835 scopus 로고    scopus 로고
    • MDL number: MFCD00003397. (accessed on 14 March)
    • Specification Sheet. MDL number: MFCD00003397. Available online: http://www.sigmaaldrich.com/Graphics/COfAInfo/SigmaSAPQM/SPEC/73/730785/730785-BULK-ALDRICH-.pdf (accessed on 14 March 2016).
    • (2016) Specification Sheet


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.