Development of fast dissolving oral films containing lercanidipine HCl nanoparticles in semicrystalline polymeric matrix for enhanced dissolution and ex vivo permeation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 103, Issue , 2016, Pages 179-191

  Chonkar, Ankita D ^a   Rao, J Venkat ^a   Managuli, Renuka S ^a   Mutalik, Srinivas ^a   Dengale, Swapnil ^a   Jain, Prateek ^a   Udupa, N ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Crystallinity; Fast dissolving oral films; Lercanidipine; Nanosuspension; Orotransmucosal

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; LERCANIDIPINE; MACROGOL 400; NANOPARTICLE; TOCOFERSOLAN; CALCIUM CHANNEL BLOCKING AGENT; DIHYDROPYRIDINE DERIVATIVE;

ARTICLE; CHEEK MUCOSA; DISPERSION; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; EMBEDDING; EVAPORATIVE ANTISOLVENT PRECIPITATION; EX VIVO STUDY; FILM; INFRARED SPECTROSCOPY; NANOSUSPENSION; NONHUMAN; PHYSICAL CHEMISTRY; POLYMERIZATION; PRECIPITATION; PREFORMULATION; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; SUSPENSION; TENSILE STRENGTH; ANIMAL; CHEMISTRY; IN VITRO STUDY; METABOLISM; MOUTH MUCOSA; ORAL DRUG ADMINISTRATION; PERMEABILITY; PIG; SOLUBILITY; X RAY DIFFRACTION;

ADMINISTRATION, ORAL; ANIMALS; CALCIUM CHANNEL BLOCKERS; DIHYDROPYRIDINES; IN VITRO TECHNIQUES; MOUTH MUCOSA; NANOPARTICLES; PERMEABILITY; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE; X-RAY DIFFRACTION;

EID: 84962920194     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2016.04.001     Document Type: Article

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