A comprehensive assessment of the association between anemia, clinical covariates and outcomes in a population-wide heart failure registry

International Journal of Cardiology

Volumn 211, Issue , 2016, Pages 124-131

  Jonsson, Asa ^a   Hallberg, Ann Charlotte ^b   Edner, Magnus ^c   Lund, Lars H ^c,d   Dahlstrom, Ulf ^b,e  

^a RYHOV COUNTY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anemia; Heart failure; Observational study; Outcomes; Reduced ejection fraction

Indexed keywords

AGE; AGED; ANEMIA; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE REGISTRY; FEMALE; GENDER; HEART EJECTION FRACTION; HEART FAILURE; HEMOGLOBIN BLOOD LEVEL; HOSPITALIZATION; HUMAN; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; NEW YORK HEART ASSOCIATION CLASS; OUTCOME ASSESSMENT; PREDICTION; PREVALENCE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; SURVIVAL RATE; SURVIVAL TIME; EPIDEMIOLOGY; FOLLOW UP; HEALTH SURVEY; MIDDLE AGED; PROSPECTIVE STUDY; REGISTER; SEX DIFFERENCE; SWEDEN; TREATMENT OUTCOME; TRENDS; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANEMIA; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; POPULATION SURVEILLANCE; PROSPECTIVE STUDIES; REGISTRIES; SEX FACTORS; SURVIVAL RATE; SWEDEN; TREATMENT OUTCOME;

EID: 84962822289     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2016.02.144     Document Type: Article

References (29)

1. T. Stewart, J. Freeman, J. Stewart, A. Sullivan, C. Ward, and G.H. Tofler Anaemia in heart failure: a prospective evaluation of clinical outcome in a community population Heart Lung Circ 19 2010 730 735
2. M. Charlot, C. Torp-Pedersen, N. Valeur, M. Seibaek, P. Weeke, and L. Kober Anaemia and long term mortality in heart failure patients: a retrospective study Open Cardiovasc. Med. J. 4 2010 173 177
3. A.P. Maggioni, C. Opasich, I. Anand, S. Barlera, E. Carbonieri, L. Gonzini, and et al. Anemia in patients with heart failure: prevalence and prognostic role in a controlled trial and in clinical practice J. Card. Fail. 11 2005 91 98
4. K.F. Adams Jr., J.H. Patterson, R.M. Oren, M.R. Mehra, C.M. O'Connor, I.L. Pina, and et al. Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry Am. Heart J. 157 2009 926 932
5. I.S. Anand, M.A. Kuskowski, T.S. Rector, V.G. Florea, R.D. Glazer, A. Hester, and et al. Anemia and change in hemoglobin over time related to mortality and morbidity in patients with chronic heart failure: results from Val-HeFT Circulation 112 2005 1121 1127
6. I. Anand, J.J. McMurray, J. Whitmore, M. Warren, A. Pham, M.A. McCamish, and et al. Anemia and its relationship to clinical outcome in heart failure Circulation 110 2004 149 154
7. M. Komajda, S.D. Anker, A. Charlesworth, D. Okonko, M. Metra, A. Di Lenarda, and et al. The impact of new onset anaemia on morbidity and mortality in chronic heart failure: results from COMET Eur. Heart J. 27 2006 1440 1446
8. E. O'Meara, T. Clayton, M.B. McEntegart, J.J. McMurray, C.C. Lang, S.D. Roger, and et al. Clinical correlates and consequences of anemia in a broad spectrum of patients with heart failure: results of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) Program Circulation 113 2006 986 994
9. M. Komajda Prevalence of anemia in patients with chronic heart failure and their clinical characteristics J. Card. Fail. 10 2004 S1 S4
10. I.S. Anand Pathogenesis of anemia in cardiorenal disease Rev. Cardiovasc. Med. 6 Suppl. 3 2005 S13 S21
11. Y.D. Tang, and S.D. Katz The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes Heart Fail. Rev. 13 2008 387 392
12. S. Hamaguchi, M. Tsuchihashi-Makaya, S. Kinugawa, T. Yokota, A. Takeshita, H. Yokoshiki, and et al. Anemia is an independent predictor of long-term adverse outcomes in patients hospitalized with heart failure in Japan. A report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) Circ. J. 73 2009 1901 1908
13. C.J. Beavers, K.A. Alburikan, J.E. Rodgers, S.P. Dunn, and B.N. Reed Distinguishing anemia and iron deficiency of heart failure: signal for severity of disease or unmet therapeutic need? Pharmacotherapy 34 2014 719 732
14. S. von Haehling, M.S. Anker, E.A. Jankowska, P. Ponikowski, and S.D. Anker Anemia in chronic heart failure: can we treat? What to treat? Heart Fail. Rev. 17 2012 203 210
15. T. McDonagh, and I.C. Macdougall Iron therapy for the treatment of iron deficiency in chronic heart failure: intravenous or oral? Eur. J. Heart Fail. 17 2015 248 262
16. P. Ponikowski, D.J. van Veldhuisen, J. Comin-Colet, G. Ertl, M. Komajda, V. Mareev, and et al. Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiencydagger Eur. Heart J. 36 2015 657 668
17. P. Ponikowski, G. Filippatos, J.C. Colet, R. Willenheimer, K. Dickstein, T. Luscher, and et al. The impact of intravenous ferric carboxymaltose on renal function: an analysis of the FAIR-HF study Eur. J. Heart Fail. 17 2015 329 339
18. A. Jonsson, M. Edner, U. Alehagen, and U. Dahlstrom Heart failure registry: a valuable tool for improving the management of patients with heart failure Eur. J. Heart Fail. 12 2010 25 31
19. D.J. Stekhoven, and P. Buhlmann MissForest - non-parametric missing value imputation for mixed-type data Bioinformatics 28 2012 112 118
20. K. Patel, G.C. Fonarow, D.W. Kitzman, I.B. Aban, T.E. Love, R.M. Allman, and et al. Angiotensin receptor blockers and outcomes in real-world older patients with heart failure and preserved ejection fraction: a propensity-matched inception cohort clinical effectiveness study Eur. J. Heart Fail. 14 2012 1179 1188
21. H.F. Groenveld, J.L. Januzzi, K. Damman, J. van Wijngaarden, H.L. Hillege, D.J. van Veldhuisen, and et al. Anemia and mortality in heart failure patients a systematic review and meta-analysis J. Am. Coll. Cardiol. 52 2008 818 827
22. K. Kajimoto, N. Sato, T. Takano, and on behalf of the investigators of the Acute Decompensated Heart Failure Syndromes r Association between anemia, clinical features and outcome in patients hospitalized for acute heart failure syndromes Eur. Heart J. Acute Cardiovasc. Care. 2014
23. A.C. Salisbury, and M. Kosiborod Outcomes associated with anemia in patients with heart failure Heart Fail Clin 6 2010 359 372
24. B. Waldum, A.S. Westheim, L. Sandvik, B. Flonaes, M. Grundtvig, L. Gullestad, and et al. Baseline anemia is not a predictor of all-cause mortality in outpatients with advanced heart failure or severe renal dysfunction. Results from the Norwegian Heart Failure Registry J. Am. Coll. Cardiol. 59 2012 371 378
25. T.H. Teng, J. Finn, and J. Hung Mild anaemia is associated with increased all-cause mortality in heart failure Heart Lung Circ 19 2010 31 37
26. R.J. Mentz, S.J. Greene, A.P. Ambrosy, M. Vaduganathan, H.P. Subacius, K. Swedberg, and et al. Clinical profile and prognostic value of anemia at the time of admission and discharge among patients hospitalized for heart failure with reduced ejection fraction: findings from the EVEREST trial Circ. Heart Fail. 7 2014 401 408
27. R. Kerzner, B.F. Gage, and M.W. Rich Anemia does not predict mortality in elderly patients with heart failure Am. J. Geriatr. Cardiol. 16 2007 92 96
28. J.A. Duncan, and A. Levin Sex, haemoglobin and kidney disease: new perspectives Eur. J. Clin. Investig. 35 Suppl. 3 2005 52 57
29. P. Redfors Long-term Post-stroke Outcome - the Sahlgrenska Academy Study on Ischemic Stroke 2014 Universtity of Gothenburg. Sahlgrenska Academy, Sweden Gothenburg