Epidemiology of Mycoplasma genitalium in British men and women aged 16-44 years: Evidence from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)

International Journal of Epidemiology

Volumn 44, Issue 6, 2015, Pages 1982-1994

  Sonnenberg, Pam ^a   Ison, Catherine A ^b   Clifton, Soazig ^a,c   Field, Nigel ^a   Tanton, Clare ^a   Soldan, Kate ^b   Beddows, Simon ^b   Alexander, Sarah ^b   Khanom, Rumena ^b   Saunders, Pamela ^b   Copas, Andrew J ^a   Wellings, Kaye ^d   Mercer, Catherine H ^a   Johnson, Anne M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c NATIONAL CENTRE FOR SOCIAL RESEARCH   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Epidemiology; Mycoplasma genitalium; Population; Sexual behaviour; STI

Indexed keywords

BACTERIUM; CONFIDENCE INTERVAL; DISEASE PREVALENCE; EPIDEMIOLOGY; ETHNICITY; HEALTH SURVEY; INFECTIVITY; LIFESTYLE; MALE BEHAVIOR; PATHOGEN; POPULATION DYNAMICS; RISK FACTOR; SEXUAL BEHAVIOR; SYMPTOM; SYPHILIS; URINE; WOMENS HEALTH;

ADOLESCENT; ADULT; ARTICLE; ASSOCIATION; BLACK PERSON; BLEEDING; CHLAMYDIA; CONDYLOMA ACUMINATUM; ETHNICITY; FEMALE; GONORRHEA; HIGH RISK BEHAVIOR; HUMAN; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MYCOPLASMA GENITALIUM; ORAL SEX; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SEXUAL BEHAVIOR; SEXUAL HEALTH; SEXUALLY TRANSMITTED DISEASE; SYMPTOM; SYPHILIS; TRICHOMONIASIS; UNITED KINGDOM; UNSAFE SEX; URINALYSIS; AGE DISTRIBUTION; CAUCASIAN; ETHNOLOGY; MICROBIOLOGY; MYCOPLASMA INFECTIONS; ODDS RATIO; SEXUALITY; STATISTICS AND NUMERICAL DATA; TRICHOMONAS VAGINITIS; URETHRITIS; YOUNG ADULT;

UNITED KINGDOM;

MYCOPLASMA GENITALIUM;

ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE DISTRIBUTION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GONORRHEA; HUMANS; MALE; MYCOPLASMA GENITALIUM; MYCOPLASMA INFECTIONS; ODDS RATIO; PREVALENCE; RISK FACTORS; SEXUAL BEHAVIOR; SEXUAL PARTNERS; SYPHILIS; TRICHOMONAS VAGINITIS; UNITED KINGDOM; UNSAFE SEX; URETHRITIS; YOUNG ADULT;

EID: 84962737609     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyv194     Document Type: Article

References (31)

1. McGowin CL, Anderson-Smits C. Mycoplasma genitalium: an emerging cause of sexually transmitted disease in women. PLoS Pathog 2011;7:e1001324.
2. Taylor-Robinson D, Jensen JS. Mycoplasma genitalium: from chrysalis to multicolored butterfly. Clin Microbiol Rev 2011;24:498-514.
3. Weinstein SA, Stiles BG. Recent perspectives in the diagnosis and evidence-based treatment of Mycoplasma genitalium. Expert Rev Anti Infect Ther 2012;10:487-99.
4. Manhart LE, Broad JM, Golden MR. Mycoplasma genitalium: Should we treat and how? Clin Infect Dis 2011;53:S129-42.
5. Horner P, Blee K, O'Mahony C, Muir P, Evans K, Radcliffe K. 2014 UK National Guideline on the Management of Non-gonococcal Urethritis. Macclesfield, UK: British Association for Sexual Health and HIV Clinical Effectiveness Group, 2014.
6. Andersen B, Sokolowski I, Ostergaard L, Moller JK, Olesen F, Jensen JS. Mycoplasma genitalium: prevalence and behavioural risk factors in the general population. Sex Transm Infect 2007;83:237-41.
7. Manhart LE, Holmes KK, Hughes JP, Houston LS, Totten PA. Mycoplasma genitalium among young adults in the United States: an emerging sexually transmitted infection. Am J Public Health 2007;97:1118-25.
8. Oakeshott P, Aghaizu A, Hay P et al. Is Mycoplasma genitalium in women the 'New Chlamydia?' A community-based prospective cohort study. Clin Infect Dis 2010;51:1160-66.
9. Svenstrup HF, Dave SS, Carder C et al. A cross-sectional study of Mycoplasma genitalium infection and correlates in women undergoing population-based screening or clinic-based testing for Chlamydia infection in London. BMJOpen 2014;4:e003947.
10. Walker J, Fairley CK, Bradshaw CS et al. The difference in determinants of Chlamydia trachomatis and Mycoplasma genitalium in a sample of young Australian women. BMC Infect Dis 2011;11:35.
11. Napierala Mavedzenge S, Weiss HA. Association of Mycoplasma genitalium and HIV infection: a systematic review and meta-analysis. AIDS 2009;23:611-20.
12. Sonnenberg P, Clifton S, Beddows S et al. Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain: findings from the National Surveys of Sexual Attitudes and Lifestyles (Natsal). Lancet 2013;382:1795-806.
13. Erens B, Phelps A, Clifton S. Methodology of the third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3). Sex Transm Infect 2014;90:84-89.
14. Erens B, Phelps A, Clifton S. The Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). Technical report. 2013. http://www.natsal.ac.uk (28 September 2015, date last accessed).
15. Wisniewski CA, White JA, Michel C-EC et al. Optimal method of collection of first-void urine for diagnosis of Chlamydia trachomatis infection in men. J Clin Microbiol 2008;46:1466-69.
16. Jensen JS, Björnelius E, Dohn B, Lidbrink P. Use of TaqMan 5' nuclease real-time PCR for quantitative detection of Mycoplasma genitalium DNA in males with and without urethritis who were attendees at a sexually transmitted disease clinic. J Clin Microbiol 2004;42:683-92.
17. Hardick J, Giles J, Hardick A, Hsieh Y-H, Quinn T, Gaydos C. Performance of the gen-probe transcription-mediated [corrected] amplification research assay compared to that of a multitarget real-time PCR for Mycoplasma genitalium detection. J Clin Microbiol 2006;44:1236-40.
18. Payne RA, Abel GA. UK indices of multiple deprivation-a way to make comparisons across constituent countries easier. Health StatQOff Natl Stat 2012;53:22-37.
19. Field N, Tanton C, Mercer CH et al. Testing for sexually transmitted infections in a population-based sexual health survey: development of an acceptable ethical approach. J Med Ethics 2012;38:380-82.
20. Hjorth SV, Björnelius E, Lidbrink P et al. Sequence-based typing of Mycoplasma genitalium reveals sexual transmission. J Clin Microbiol 2006;44:2078-83.
21. Ma L, Taylor S, Jensen JS, Myers L, Lillis R, Martin DH. Short tandem repeat sequences in the Mycoplasma genitalium genome and their use in a multilocus genotyping system. BMC Microbiol 2008;8:130.
22. Fenton KA, Johnson AM, McManus S, Erens B. Measuring sexual behaviour: methodological challenges in survey research. Sex Transm Infect 2001;77:84-92.
23. Redmond SM, Alexander-Kisslig K, Woodhall SC et al. Genital Chlamydia prevalence in Europe and Non-European high income countries: systematic review and meta-analysis. PLoS One 2015;10:e0115753.
24. Wroblewski JKH, Manhart LE, Dickey KA, HudspethMK, Totten PA. Comparison of transcription-mediated amplification and PCR assay results for various genital specimen types for detection of Mycoplasma genitalium. J Clin Microbiol 2006;44:3306-12.
25. Hancock EB, Manhart LE, Nelson SJ, Kerani R, Wroblewski JKH, Totten PA. Comprehensive assessment of sociodemographic and behavioral risk factors for Mycoplasma genitalium infection in women. Sex Transm Dis 2010;37:777-83.
26. Mercer CH, Copas AJ, Sonnenberg P et al. Who has sex with whom? Characteristics of heterosexual partnerships reported in a national probability survey and implications for STI risk. Int J Epidemiol 2009;38:206-14.
27. Lazarus R, Vercelli D, Palmer LJ et al. Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease. Immunol Rev 2002;190:9-25.
28. Ravel J, Gajer P, Abdo Z et al. Vaginal microbiome of reproductive-age women. Proc Natl Acad Sci U S A 2011;108(Suppl 1): 4680-87.
29. Public Health England. Sexually transmitted infections and chlamydia screening in England, 2013. Health Prot Rep 2014;8:24.
30. Tarney CM, Han J. Postcoital bleeding: a review on etiology, diagnosis, and management. Obstet Gynecol Int 2014;2014:e192087.
31. Field N, Kennedy I, Folkard K et al. Screening for gonorrhoea using samples collected through the English National Chlamydia Screening Programme and risk of false positives: a national survey of local authorities. BMJ Open 2014;4:e006067