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Volumn 142, Issue 1, 2016, Pages 199-205

The biological significance and clinical applications of exosomes in ovarian cancer

Author keywords

Bio marker; Exosomes; Hypoxia; micro RNA; Ovarian cancer

Indexed keywords

ALDEHYDE REDUCTASE; ALIX PROTEIN; BETA CATENIN; BIOLOGICAL MARKER; CASEIN KINASE II; CAVEOLIN 1; CD37 ANTIGEN; CD53 ANTIGEN; CD63 ANTIGEN; CD81 ANTIGEN; CD82 ANTIGEN; CLAUDIN 4; EPITHELIAL CELL ADHESION MOLECULE; GELATINASE A; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 84; HEAT SHOCK PROTEIN 90; HEPATOMA DERIVED GROWTH FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; LIPOCORTIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; MICRORNA; PEROXIREDOXIN; RNA INDUCED SILENCING COMPLEX; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; TUMOR MARKER;

EID: 84962675054     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2016.03.036     Document Type: Review
Times cited : (73)

References (70)
  • 1
    • 21844468743 scopus 로고    scopus 로고
    • Unconventional secretory routes: Direct protein export across the plasma membrane of mammalian cells
    • W. Nickel Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells Traffic 6 2005 607 614
    • (2005) Traffic , vol.6 , pp. 607-614
    • Nickel, W.1
  • 2
    • 68549132400 scopus 로고    scopus 로고
    • Ovarian cancer-associated ascites demonstrates altered immune environment: Implications for antitumor immunity
    • R.L. Giuntoli II, T.J. Webb, A. Zoso, O. Rogers, T.P. Diaz-Montes, R.E. Bristow, and et al. Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity Anticancer Res. 29 2009 2875 2884
    • (2009) Anticancer Res. , vol.29 , pp. 2875-2884
    • Giuntoli, I.I.R.L.1    Webb, T.J.2    Zoso, A.3    Rogers, O.4    Diaz-Montes, T.P.5    Bristow, R.E.6
  • 3
    • 84892674862 scopus 로고    scopus 로고
    • Exosomes in plasma of patients with ovarian carcinoma: Potential biomarkers of tumor progression and response to therapy
    • M. Szajnik, M. Derbis, M. Lach, P. Patalas, M. Michalak, H. Drzewiecka, and et al. Exosomes in plasma of patients with ovarian carcinoma: potential biomarkers of tumor progression and response to therapy Gynecol. Obstet. Suppl. 4 2013 3
    • (2013) Gynecol. Obstet. , pp. 3
    • Szajnik, M.1    Derbis, M.2    Lach, M.3    Patalas, P.4    Michalak, M.5    Drzewiecka, H.6
  • 4
    • 36348935057 scopus 로고    scopus 로고
    • Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
    • S. Runz, S. Keller, C. Rupp, A. Stoeck, Y. Issa, D. Koensgen, and et al. Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM Gynecol. Oncol. 107 2007 563 571
    • (2007) Gynecol. Oncol. , vol.107 , pp. 563-571
    • Runz, S.1    Keller, S.2    Rupp, C.3    Stoeck, A.4    Issa, Y.5    Koensgen, D.6
  • 5
    • 84901366761 scopus 로고    scopus 로고
    • Interactions between exosomes from breast cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells
    • S. Dutta, C. Warshall, C. Bandyopadhyay, D. Dutta, and B. Chandran Interactions between exosomes from breast cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells PLoS One 9 2014 e97580
    • (2014) PLoS One , vol.9
    • Dutta, S.1    Warshall, C.2    Bandyopadhyay, C.3    Dutta, D.4    Chandran, B.5
  • 7
    • 84928588794 scopus 로고    scopus 로고
    • Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein
    • M.M. Lv, X.Y. Zhu, W.X. Chen, S.L. Zhong, Q. Hu, T.F. Ma, and et al. Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein Tumour Biol. 35 2014 10773 10779
    • (2014) Tumour Biol. , vol.35 , pp. 10773-10779
    • Lv, M.M.1    Zhu, X.Y.2    Chen, W.X.3    Zhong, S.L.4    Hu, Q.5    Ma, T.F.6
  • 8
    • 0020606494 scopus 로고
    • Membrane-associated" immunoglobulins in cyst and ascites fluids of ovarian cancer patients
    • D.D. Taylor, H.D. Homesley, and G.J. Doellgast "Membrane-associated" immunoglobulins in cyst and ascites fluids of ovarian cancer patients Am. J. Reprod. Immunol. 3 1983 7 11
    • (1983) Am. J. Reprod. Immunol. , vol.3 , pp. 7-11
    • Taylor, D.D.1    Homesley, H.D.2    Doellgast, G.J.3
  • 9
    • 79953081976 scopus 로고    scopus 로고
    • Interaction and uptake of exosomes by ovarian cancer cells
    • C. Escrevente, S. Keller, P. Altevogt, and J. Costa Interaction and uptake of exosomes by ovarian cancer cells BMC Cancer 11 2011 108
    • (2011) BMC Cancer , vol.11 , pp. 108
    • Escrevente, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 12
    • 14844336294 scopus 로고    scopus 로고
    • Tumour-derived exosomes or microvesicles: Another mechanism of tumour escape from the host immune system?
    • T.L. Whiteside Tumour-derived exosomes or microvesicles: another mechanism of tumour escape from the host immune system? Br. J. Cancer 92 2005 209 211
    • (2005) Br. J. Cancer , vol.92 , pp. 209-211
    • Whiteside, T.L.1
  • 13
    • 14844334129 scopus 로고    scopus 로고
    • Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
    • D.D. Taylor, and C. Gercel-Taylor Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects Br. J. Cancer 92 2005 305 311
    • (2005) Br. J. Cancer , vol.92 , pp. 305-311
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 17
    • 84928243525 scopus 로고    scopus 로고
    • Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication
    • V.O. Shender, M.S. Pavlyukov, R.H. Ziganshin, G.P. Arapidi, S.I. Kovalchuk, N.A. Anikanov, and et al. Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication Mol. Cell. Proteomics 13 2014 3558 3571
    • (2014) Mol. Cell. Proteomics , vol.13 , pp. 3558-3571
    • Shender, V.O.1    Pavlyukov, M.S.2    Ziganshin, R.H.3    Arapidi, G.P.4    Kovalchuk, S.I.5    Anikanov, N.A.6
  • 18
    • 84947561403 scopus 로고    scopus 로고
    • High LIN28A expressing ovarian cancer cells secrete exosomes that induce invasion and migration in HEK293 cells
    • V.A. Enriquez, E.R. Cleys, J.C. Da Silveira, M.A. Spillman, Q.A. Winger, and G.J. Bouma High LIN28A expressing ovarian cancer cells secrete exosomes that induce invasion and migration in HEK293 cells Biomed. Res. Int. 2015 2015 701390
    • (2015) Biomed. Res. Int. , vol.2015 , pp. 701390
    • Enriquez, V.A.1    Cleys, E.R.2    Da Silveira, J.C.3    Spillman, M.A.4    Winger, Q.A.5    Bouma, G.J.6
  • 19
    • 84863010943 scopus 로고    scopus 로고
    • Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients
    • J. Yin, X. Yan, X. Yao, Y. Zhang, Y. Shan, N. Mao, and et al. Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients J. Cell. Mol. Med. 16 2012 337 348
    • (2012) J. Cell. Mol. Med. , vol.16 , pp. 337-348
    • Yin, J.1    Yan, X.2    Yao, X.3    Zhang, Y.4    Shan, Y.5    Mao, N.6
  • 20
    • 67650531887 scopus 로고    scopus 로고
    • Microvesicles: Messengers and mediators of tumor progression
    • K. Al-Nedawi, B. Meehan, and J. Rak Microvesicles: messengers and mediators of tumor progression Cell Cycle 8 2009 2014 2018
    • (2009) Cell Cycle , vol.8 , pp. 2014-2018
    • Al-Nedawi, K.1    Meehan, B.2    Rak, J.3
  • 22
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • D.D. Taylor, and C. Gercel-Taylor MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer Gynecol. Oncol. 110 2008 13 21
    • (2008) Gynecol. Oncol. , vol.110 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 24
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 25
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • E. Maniataki, and Z. Mourelatos A human, ATP-independent, RISC assembly machine fueled by pre-miRNA Genes Dev. 19 2005 2979 2990
    • (2005) Genes Dev. , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 26
  • 27
    • 84858379476 scopus 로고    scopus 로고
    • MicroRNAs in stress signaling and human disease
    • J.T. Mendell, and E.N. Olson MicroRNAs in stress signaling and human disease Cell 148 2012 1172 1187
    • (2012) Cell , vol.148 , pp. 1172-1187
    • Mendell, J.T.1    Olson, E.N.2
  • 30
    • 84922527336 scopus 로고    scopus 로고
    • Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells
    • M.L. Squadrito, C. Baer, F. Burdet, C. Maderna, G.D. Gilfillan, R. Lyle, and et al. Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells Cell Rep. 8 2014 1432 1446
    • (2014) Cell Rep. , vol.8 , pp. 1432-1446
    • Squadrito, M.L.1    Baer, C.2    Burdet, F.3    Maderna, C.4    Gilfillan, G.D.5    Lyle, R.6
  • 31
    • 84874413414 scopus 로고    scopus 로고
    • Characterization and proteomic analysis of ovarian cancer-derived exosomes
    • B. Liang, P. Peng, S. Chen, L. Li, M. Zhang, D. Cao, and et al. Characterization and proteomic analysis of ovarian cancer-derived exosomes J. Proteome 80 2013 171 182
    • (2013) J. Proteome , vol.80 , pp. 171-182
    • Liang, B.1    Peng, P.2    Chen, S.3    Li, L.4    Zhang, M.5    Cao, D.6
  • 32
    • 84891514593 scopus 로고    scopus 로고
    • Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200
    • M. Kobayashi, C. Salomon, J. Tapia, S.E. Illanes, M.D. Mitchell, and G.E. Rice Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200 J. Transl. Med. 12 2014 4
    • (2014) J. Transl. Med. , vol.12 , pp. 4
    • Kobayashi, M.1    Salomon, C.2    Tapia, J.3    Illanes, S.E.4    Mitchell, M.D.5    Rice, G.E.6
  • 33
    • 78649366841 scopus 로고    scopus 로고
    • The role of microRNAs in ovarian cancer initiation and progression
    • S.D. Li, J.R. Zhang, Y.Q. Wang, and X.P. Wan The role of microRNAs in ovarian cancer initiation and progression J. Cell. Mol. Med. 14 2010 2240 2249
    • (2010) J. Cell. Mol. Med. , vol.14 , pp. 2240-2249
    • Li, S.D.1    Zhang, J.R.2    Wang, Y.Q.3    Wan, X.P.4
  • 35
    • 84908494725 scopus 로고    scopus 로고
    • Programmed cell death 4 and microRNA 21 inverse expression is maintained in cells and exosomes from ovarian serous carcinoma effusions
    • R. Cappellesso, A. Tinazzi, T. Giurici, F. Simonato, V. Guzzardo, L. Ventura, and et al. Programmed cell death 4 and microRNA 21 inverse expression is maintained in cells and exosomes from ovarian serous carcinoma effusions Cancer Cytopathol. 122 2014 685 693
    • (2014) Cancer Cytopathol. , vol.122 , pp. 685-693
    • Cappellesso, R.1    Tinazzi, A.2    Giurici, T.3    Simonato, F.4    Guzzardo, V.5    Ventura, L.6
  • 36
    • 84906834990 scopus 로고    scopus 로고
    • Exosome-derived miRNAs and ovarian carcinoma progression
    • O. Vaksman, C. Trope, B. Davidson, and R. Reich Exosome-derived miRNAs and ovarian carcinoma progression Carcinogenesis 35 2014 2113 2120
    • (2014) Carcinogenesis , vol.35 , pp. 2113-2120
    • Vaksman, O.1    Trope, C.2    Davidson, B.3    Reich, R.4
  • 37
    • 84866502787 scopus 로고    scopus 로고
    • Hypoxic enhancement of exosome release by breast cancer cells
    • H.W. King, M.Z. Michael, and J.M. Gleadle Hypoxic enhancement of exosome release by breast cancer cells BMC Cancer 12 2012 421
    • (2012) BMC Cancer , vol.12 , pp. 421
    • King, H.W.1    Michael, M.Z.2    Gleadle, J.M.3
  • 38
    • 84890313522 scopus 로고    scopus 로고
    • Exosomes in cancer development, metastasis, and drug resistance: A comprehensive review
    • A.S. Azmi, B. Bao, and F.H. Sarkar Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review Cancer Metastasis Rev. 32 2013 623 642
    • (2013) Cancer Metastasis Rev. , vol.32 , pp. 623-642
    • Azmi, A.S.1    Bao, B.2    Sarkar, F.H.3
  • 39
    • 63649092087 scopus 로고    scopus 로고
    • Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
    • S. Keller, A.K. Konig, F. Marme, S. Runz, S. Wolterink, D. Koensgen, and et al. Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Cancer Lett. 278 2009 73 81
    • (2009) Cancer Lett. , vol.278 , pp. 73-81
    • Keller, S.1    Konig, A.K.2    Marme, F.3    Runz, S.4    Wolterink, S.5    Koensgen, D.6
  • 40
    • 79952070774 scopus 로고    scopus 로고
    • The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
    • H. Peinado, S. Lavotshkin, and D. Lyden The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts Semin. Cancer Biol. 21 2011 139 146
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 139-146
    • Peinado, H.1    Lavotshkin, S.2    Lyden, D.3
  • 43
    • 84930763705 scopus 로고    scopus 로고
    • Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
    • A. Ramteke, H. Ting, C. Agarwal, S. Mateen, R. Somasagara, A. Hussain, and et al. Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules Mol. Carcinog. 54 2015 554 565
    • (2015) Mol. Carcinog. , vol.54 , pp. 554-565
    • Ramteke, A.1    Ting, H.2    Agarwal, C.3    Mateen, S.4    Somasagara, R.5    Hussain, A.6
  • 46
    • 84906212380 scopus 로고    scopus 로고
    • Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor
    • G.A. McCann, S. Naidu, K.S. Rath, H.K. Bid, B.J. Tierney, A. Suarez, and et al. Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor Oncoscience 1 2014 216 228
    • (2014) Oncoscience , vol.1 , pp. 216-228
    • McCann, G.A.1    Naidu, S.2    Rath, K.S.3    Bid, H.K.4    Tierney, B.J.5    Suarez, A.6
  • 47
    • 84975142906 scopus 로고    scopus 로고
    • Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment
    • L. Rauschenberger, D. Staar, K. Thom, C. Scharf, S. Venz, G. Homuth, and et al. Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment Prostate 2015
    • (2015) Prostate
    • Rauschenberger, L.1    Staar, D.2    Thom, K.3    Scharf, C.4    Venz, S.5    Homuth, G.6
  • 48
    • 84939269936 scopus 로고    scopus 로고
    • Exosomes: Emerging biomarkers and targets for ovarian cancer
    • M.K. Tang, and A.S. Wong Exosomes: emerging biomarkers and targets for ovarian cancer Cancer Lett. 367 2015 26 33
    • (2015) Cancer Lett. , vol.367 , pp. 26-33
    • Tang, M.K.1    Wong, A.S.2
  • 49
    • 85009992317 scopus 로고    scopus 로고
    • Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis
    • W. Zhang, P. Peng, Y. Kuang, J. Yang, D. Cao, Y. You, and et al. Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis Tumour Biol. 2015
    • (2015) Tumour Biol.
    • Zhang, W.1    Peng, P.2    Kuang, Y.3    Yang, J.4    Cao, D.5    You, Y.6
  • 50
    • 84944465382 scopus 로고    scopus 로고
    • An optimized procedure for exosome isolation and analysis using serum samples: Application to cancer biomarker discovery
    • M. Li, A.J. Rai, G. Joel DeCastro, E. Zeringer, T. Barta, S. Magdaleno, and et al. An optimized procedure for exosome isolation and analysis using serum samples: application to cancer biomarker discovery Methods 87 2015 26 30
    • (2015) Methods , vol.87 , pp. 26-30
    • Li, M.1    Rai, A.J.2    Joel Decastro, G.3    Zeringer, E.4    Barta, T.5    Magdaleno, S.6
  • 54
    • 27644524811 scopus 로고    scopus 로고
    • Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
    • R. Safaei, B.J. Larson, T.C. Cheng, M.A. Gibson, S. Otani, W. Naerdemann, and et al. Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells Mol. Cancer Ther. 4 2005 1595 1604
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1595-1604
    • Safaei, R.1    Larson, B.J.2    Cheng, T.C.3    Gibson, M.A.4    Otani, S.5    Naerdemann, W.6
  • 55
    • 84929939631 scopus 로고    scopus 로고
    • The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
    • R.C. Pink, P. Samuel, D. Massa, D.P. Caley, S.A. Brooks, and D.R. Carter The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells Gynecol. Oncol. 137 2015 143 151
    • (2015) Gynecol. Oncol. , vol.137 , pp. 143-151
    • Pink, R.C.1    Samuel, P.2    Massa, D.3    Caley, D.P.4    Brooks, S.A.5    Carter, D.R.6
  • 56
    • 84991349195 scopus 로고    scopus 로고
    • Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells
    • K. Weiner-Gorzel, E. Dempsey, M. Milewska, A. McGoldrick, V. Toh, A. Walsh, and et al. Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells Cancer med. 4 2015 745 758
    • (2015) Cancer Med. , vol.4 , pp. 745-758
    • Weiner-Gorzel, K.1    Dempsey, E.2    Milewska, M.3    McGoldrick, A.4    Toh, V.5    Walsh, A.6
  • 58
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • K. Trajkovic, C. Hsu, S. Chiantia, L. Rajendran, D. Wenzel, F. Wieland, and et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes Science 319 2008 1244 1247
    • (2008) Science , vol.319 , pp. 1244-1247
    • Trajkovic, K.1    Hsu, C.2    Chiantia, S.3    Rajendran, L.4    Wenzel, D.5    Wieland, F.6
  • 59
    • 84858342603 scopus 로고    scopus 로고
    • DeltaNp63 (p40) and thyroid transcription factor-1 immunoreactivity on small biopsies or cellblocks for typing non-small cell lung cancer: A novel two-hit, sparing-material approach
    • G. Pelosi, A. Fabbri, F. Bianchi, P. Maisonneuve, G. Rossi, M. Barbareschi, and et al. DeltaNp63 (p40) and thyroid transcription factor-1 immunoreactivity on small biopsies or cellblocks for typing non-small cell lung cancer: a novel two-hit, sparing-material approach J. Thorac. Oncol. 7 2012 281 290
    • (2012) J. Thorac. Oncol. , vol.7 , pp. 281-290
    • Pelosi, G.1    Fabbri, A.2    Bianchi, F.3    Maisonneuve, P.4    Rossi, G.5    Barbareschi, M.6
  • 60
    • 76649097628 scopus 로고    scopus 로고
    • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    • F. Chalmin, S. Ladoire, G. Mignot, J. Vincent, M. Bruchard, J.P. Remy-Martin, and et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells J. Clin. Invest. 120 2010 457 471
    • (2010) J. Clin. Invest. , vol.120 , pp. 457-471
    • Chalmin, F.1    Ladoire, S.2    Mignot, G.3    Vincent, J.4    Bruchard, M.5    Remy-Martin, J.P.6
  • 61
    • 79953136097 scopus 로고    scopus 로고
    • Rab27a and Rab27b control different steps of the exosome secretion pathway
    • M. Ostrowski, N.B. Carmo, S. Krumeich, I. Fanget, G. Raposo, A. Savina, and et al. Rab27a and Rab27b control different steps of the exosome secretion pathway Nat. Cell Biol. 12 19-30; sup 2010 1 13
    • (2010) Nat. Cell Biol. , vol.12 , Issue.19-30 , pp. 1-13
    • Ostrowski, M.1    Carmo, N.B.2    Krumeich, S.3    Fanget, I.4    Raposo, G.5    Savina, A.6
  • 63
    • 18144372419 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: Results of the first phase i clinical trial
    • B. Escudier, T. Dorval, N. Chaput, F. Andre, M.P. Caby, S. Novault, and et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial J. Transl. Med. 3 2005 10
    • (2005) J. Transl. Med. , vol.3 , pp. 10
    • Escudier, B.1    Dorval, T.2    Chaput, N.3    Andre, F.4    Caby, M.P.5    Novault, S.6
  • 64
    • 18144369346 scopus 로고    scopus 로고
    • A phase i study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    • M.A. Morse, J. Garst, T. Osada, S. Khan, A. Hobeika, T.M. Clay, and et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer J. Transl. Med. 3 2005 9
    • (2005) J. Transl. Med. , vol.3 , pp. 9
    • Morse, M.A.1    Garst, J.2    Osada, T.3    Khan, S.4    Hobeika, A.5    Clay, T.M.6
  • 65
    • 41149172340 scopus 로고    scopus 로고
    • Phase i clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    • S. Dai, D. Wei, Z. Wu, X. Zhou, X. Wei, H. Huang, and et al. Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer Mol. Ther. 16 2008 782 790
    • (2008) Mol. Ther. , vol.16 , pp. 782-790
    • Dai, S.1    Wei, D.2    Wu, Z.3    Zhou, X.4    Wei, X.5    Huang, H.6
  • 66
    • 80855144189 scopus 로고    scopus 로고
    • Increasing vaccine potency through exosome antigen targeting
    • Z.C. Hartman, J. Wei, O.K. Glass, H. Guo, G. Lei, X.Y. Yang, and et al. Increasing vaccine potency through exosome antigen targeting Vaccine 29 2011 9361 9367
    • (2011) Vaccine , vol.29 , pp. 9361-9367
    • Hartman, Z.C.1    Wei, J.2    Glass, O.K.3    Guo, H.4    Lei, G.5    Yang, X.Y.6
  • 67
    • 77956264919 scopus 로고    scopus 로고
    • A novel nanoparticle drug delivery system: The anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes
    • D. Sun, X. Zhuang, X. Xiang, Y. Liu, S. Zhang, C. Liu, and et al. A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes Mol. Ther. 18 2010 1606 1614
    • (2010) Mol. Ther. , vol.18 , pp. 1606-1614
    • Sun, D.1    Zhuang, X.2    Xiang, X.3    Liu, Y.4    Zhang, S.5    Liu, C.6
  • 68
    • 84922224260 scopus 로고    scopus 로고
    • Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer
    • Y. Tian, X. Jiang, X. Chen, Z. Shao, and W. Yang Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer Adv. Mater. 26 2014 7393 7398
    • (2014) Adv. Mater. , vol.26 , pp. 7393-7398
    • Tian, Y.1    Jiang, X.2    Chen, X.3    Shao, Z.4    Yang, W.5
  • 69
    • 84899825335 scopus 로고
    • A comprehensive overview of exosomes as drug delivery vehicles - Endogenous nanocarriers for targeted cancer therapy
    • K.B. Johnsen, J.M. Gudbergsson, M.N. Skov, L. Pilgaard, T. Moos, and M. Duroux A comprehensive overview of exosomes as drug delivery vehicles - endogenous nanocarriers for targeted cancer therapy Biochim. Biophys. Acta 2014 1846 75 87
    • (1846) Biochim. Biophys. Acta , vol.2014 , pp. 75-87
    • Johnsen, K.B.1    Gudbergsson, J.M.2    Skov, M.N.3    Pilgaard, L.4    Moos, T.5    Duroux, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.