A recombinant DNA vaccine protects mice deficient in the alpha/beta interferon receptor against lethal challenge with Usutu virus

Vaccine

Volumn 34, Issue 18, 2016, Pages 2066-2073

  Martín Acebes, Miguel A ^a,b   Blázquez, Ana Belén ^a   Cañas Arranz, Rodrigo ^b   Vázquez Calvo, Ángela ^a   Merino Ramos, Teresa ^a   Escribano Romero, Estela ^a   Sobrino, Francisco ^b   Saiz, Juan Carlos ^a  

^a INIA   (Spain)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

Antibodies; DNA vaccine; Flavivirus; IFNAR mice; Usutu virus

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; CALNEXIN; DNA VACCINE; M PROTEIN; NEUTRALIZING ANTIBODY; PLASMID DNA; PROTEIN C; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN E; JAPANESE ENCEPHALITIS VACCINE; VIRUS ANTIBODY; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL NUCLEUS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA IMMUNIZATION; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLAVIVIRUS; FLAVIVIRUS INFECTION; HUMORAL IMMUNITY; IMMUNOFLUORESCENCE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; USUTU VIRUS; USUTU VIRUS INFECTION; VERO CELL LINE; VIRUS CELL INTERACTION; VIRUS LIKE AGENT; WESTERN BLOTTING; ANIMAL; BLOOD; FLAVIVIRUS INFECTIONS; GENETICS; IMMUNOLOGY; JAPANESE ENCEPHALITIS VIRUS; KNOCKOUT MOUSE;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; ENCEPHALITIS VIRUSES, JAPANESE; FLAVIVIRUS INFECTIONS; JAPANESE ENCEPHALITIS VACCINES; MICE; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA; VACCINES, DNA; VIRAL ENVELOPE PROTEINS;

EID: 84962603226     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2016.03.015     Document Type: Article

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