메뉴 건너뛰기




Volumn 19, Issue 3, 2016, Pages 253-265

In Vitro and in Vivo Immunomodulatory Activity of Okra (Abelmoschus esculentus L.) Polysaccharides

Author keywords

cytokine; nitric oxide; okra (Abelmoschus esculentus L.); polysaccharide; RAW264.7

Indexed keywords

CYCLOPHOSPHAMIDE; DIETHYLAMINOETHYL CELLULOSE; GALACTOSE; GALACTURONIC ACID; GAMMA INTERFERON; GLUCOSE; GLUCURONIC ACID; IMMUNOMODULATING AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; NITRIC OXIDE; OKRA EXTRACT; PLANT EXTRACT; POLYSACCHARIDE; RHAMNOGALACTURONAN 1; RHAMNOSE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOLOGIC FACTOR;

EID: 84962567752     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2015.3513     Document Type: Article
Times cited : (66)

References (48)
  • 1
    • 1642344593 scopus 로고    scopus 로고
    • Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa
    • Lengsfeld C, Titgemeyer F, Faller G, Hensel A: Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Agric Food Chem 2004;52:1495-1503.
    • (2004) J Agric Food Chem , vol.52 , pp. 1495-1503
    • Lengsfeld, C.1    Titgemeyer, F.2    Faller, G.3    Hensel, A.4
  • 2
    • 0036889613 scopus 로고    scopus 로고
    • In vivo gastroprotective effects of five Turkish folk remedies against ethanol-induced lesions
    • Gürbüz I, Ustün O, Yesxilada E, Sezik E, Akyürek N: In vivo gastroprotective effects of five Turkish folk remedies against ethanol-induced lesions. J Ethnopharmacol 2002;83:241-244.
    • (2002) J Ethnopharmacol , vol.83 , pp. 241-244
    • Gürbüz, I.1    Ustün, O.2    Yesxilada, E.3    Sezik, E.4    Akyürek, N.5
  • 5
    • 25444527021 scopus 로고    scopus 로고
    • Antioxidant activity of five vegetables traditionally consumed by South-Asian migrants in Bradford, Yorkshire, UK
    • Ansari NM, Houlihan L, Hussain B, Pieroni A: Antioxidant activity of five vegetables traditionally consumed by South-Asian migrants in Bradford, Yorkshire, UK. Phytother Res 2005;19: 907-911.
    • (2005) Phytother Res , vol.19 , pp. 907-911
    • Ansari, N.M.1    Houlihan, L.2    Hussain, B.3    Pieroni, A.4
  • 7
    • 80255129700 scopus 로고    scopus 로고
    • Anticonvulsant, antidepressant-like activity of Abelmoschus manihot ethanol extract and its potential active components in vivo
    • Guo J, Xue C, Duan JA, Qian D, Tang Y, You Y: Anticonvulsant, antidepressant-like activity of Abelmoschus manihot ethanol extract and its potential active components in vivo. Phytomedicine 2011;18:1250-1254.
    • (2011) Phytomedicine , vol.18 , pp. 1250-1254
    • Guo, J.1    Xue, C.2    Duan, J.A.3    Qian, D.4    Tang, Y.5    You, Y.6
  • 9
    • 77954503846 scopus 로고    scopus 로고
    • Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells
    • Vayssade M, Sengkhamparn N, Verhoef R, et al.: Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells. Phytother Res 2010;24:982-989.
    • (2010) Phytother Res , vol.24 , pp. 982-989
    • Vayssade, M.1    Sengkhamparn, N.2    Verhoef, R.3
  • 10
    • 67349241254 scopus 로고    scopus 로고
    • Chemical composition and the antioxidative properties of Nigerian okra seed (Abelmoschus esculentus Moench) flour
    • Adelakun OE, Oyelade OJ, Ade-Omowaye BI, Adeyemi IA, Van de Venter M: Chemical composition and the antioxidative properties of Nigerian okra seed (Abelmoschus esculentus Moench) flour. Food Chem Toxicol 2009;47: 1123-1126.
    • (2009) Food Chem Toxicol , vol.47 , pp. 1123-1126
    • Adelakun, O.E.1    Oyelade, O.J.2    Ade-Omowaye, B.I.3    Adeyemi, I.A.4    Van De Venter, M.5
  • 12
    • 84871913236 scopus 로고    scopus 로고
    • Investigation of in vivo antioxidant property of Abelmoschus esculentus (L) moench. Fruit seed and peel powders in streptozotocin-induced diabetic rats
    • Sabitha V, Ramachandran S, Naveen KR, Panneerselvam K: Investigation of in vivo antioxidant property of Abelmoschus esculentus (L) moench. fruit seed and peel powders in streptozotocin-induced diabetic rats. J Ayurveda Integr Med 2012;34:188-193.
    • (2012) J Ayurveda Integr Med , vol.34 , pp. 188-193
    • Sabitha, V.1    Ramachandran, S.2    Naveen, K.R.3    Panneerselvam, K.4
  • 13
    • 80051622037 scopus 로고    scopus 로고
    • Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays
    • Gul MZ, Bhakshu LM, Ahmad F, Kondapi AK, Qureshi IA, Ghazi IA: Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays. BMC Complement Altern Med 2011;11:64-78.
    • (2011) BMC Complement Altern Med , vol.11 , pp. 64-78
    • Gul, M.Z.1    Bhakshu, L.M.2    Ahmad, F.3    Kondapi, A.K.4    Qureshi, I.A.5    Ghazi, I.A.6
  • 15
    • 84860329117 scopus 로고    scopus 로고
    • 'Okra' Hibiscus esculentus L: A study of its hepatoprotective activity
    • Alqasoumi SI: 'Okra' Hibiscus esculentus L: A study of its hepatoprotective activity. Saudi Pharm J 2012;20:135-141.
    • (2012) Saudi Pharm J , vol.20 , pp. 135-141
    • Alqasoumi, S.I.1
  • 16
    • 84861580579 scopus 로고    scopus 로고
    • Composition analysis and immunomodulatory effect of okra (Abelmoschus esculentus L.) extract
    • Sheu SC, Lai MH: Composition analysis and immunomodulatory effect of okra (Abelmoschus esculentus L.) extract. Food Chem 2012;134:1906-1911.
    • (2012) Food Chem , vol.134 , pp. 1906-1911
    • Sheu, S.C.1    Lai, M.H.2
  • 17
    • 33947108524 scopus 로고    scopus 로고
    • Use of plant residues for improving soil fertility, pod nutrients, root growth and pod weight of okra (Abelmoschus esculentus L.)
    • Moyin-Jesu EI: Use of plant residues for improving soil fertility, pod nutrients, root growth and pod weight of okra (Abelmoschus esculentus L.). Bioresour Technol 2007;98:2057-2064.
    • (2007) Bioresour Technol , vol.98 , pp. 2057-2064
    • Moyin-Jesu, E.I.1
  • 18
    • 43449113522 scopus 로고    scopus 로고
    • Identification and quantification of polyphenolic compounds from okra seeds and skins
    • Arapitsas P: Identification and quantification of polyphenolic compounds from okra seeds and skins. Food Chem 2008;110: 1041-1045.
    • (2008) Food Chem , vol.110 , pp. 1041-1045
    • Arapitsas, P.1
  • 19
    • 7044250957 scopus 로고
    • The isolation of the components of streptococcal nucleoproteins in serologically active form
    • Sevag MG, Lackman DB, Smolens J: The isolation of the components of streptococcal nucleoproteins in serologically active form. J Biol Chem 1938;124:425-436.
    • (1938) J Biol Chem , vol.124 , pp. 425-436
    • Sevag, M.G.1    Lackman, D.B.2    Smolens, J.3
  • 20
    • 33749946901 scopus 로고
    • Colorimetric method for determination of sugars and related substances
    • DuBois M, Gilles KA, Hamilton JK, Robers PA, Smith F: Colorimetric method for determination of sugars and related substances. Anal Chem 1956;28:350-356.
    • (1956) Anal Chem , vol.28 , pp. 350-356
    • DuBois, M.1    Gilles, K.A.2    Hamilton, J.K.3    Robers, P.A.4    Smith, F.5
  • 21
    • 0025848138 scopus 로고
    • Measurement of uronic acids without interference from neutral sugars
    • Filisetti-Cozzi TM, Carpita NC: Measurement of uronic acids without interference from neutral sugars. Anal Biochem 1991; 197:157-162.
    • (1991) Anal Biochem , vol.197 , pp. 157-162
    • Filisetti-Cozzi, T.M.1    Carpita, N.C.2
  • 22
    • 67349202467 scopus 로고    scopus 로고
    • Total fractionation and characterization of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer
    • Zhang X, Yu L, Bi HT, et al.: Total fractionation and characterization of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer. Carbohydr Polym 2009;77:544-552.
    • (2009) Carbohydr Polym , vol.77 , pp. 544-552
    • Zhang, X.1    Yu, L.2    Bi, H.T.3
  • 23
    • 73649123150 scopus 로고    scopus 로고
    • Rhamnogalacturonan i domains from ginseng pectin
    • Yu L, Zhang X, Li SS: Rhamnogalacturonan I domains from ginseng pectin. Carbohydr Polym 2010;79:811-817.
    • (2010) Carbohydr Polym , vol.79 , pp. 811-817
    • Yu, L.1    Zhang, X.2    Li, S.S.3
  • 24
    • 0024355993 scopus 로고
    • High-performance liquid chromatography of reducing carbohydrates as strongly ultraviolet-absorbing and electrochemically sensitive 1-phenyl-3-methyl-5-pyrazolone derivatives
    • Honda S, Akao E, Suzuki S, Okuda M, Kakehi K, Nakamura J: High-performance liquid chromatography of reducing carbohydrates as strongly ultraviolet-absorbing and electrochemically sensitive 1-phenyl-3-methyl-5-pyrazolone derivatives. Anal Biochem 1989;180:351-357.
    • (1989) Anal Biochem , vol.180 , pp. 351-357
    • Honda, S.1    Akao, E.2    Suzuki, S.3    Okuda, M.4    Kakehi, K.5    Nakamura, J.6
  • 25
    • 82255180880 scopus 로고    scopus 로고
    • SiRNA targeting mCD14 inhibits TNF-A, MIP-2, and IL-6 secretion and NO production from LPSinduced RAW264.7 cells
    • Lei M, Jiao H, Liu T, et al.: siRNA targeting mCD14 inhibits TNF-a, MIP-2, and IL-6 secretion and NO production from LPSinduced RAW264.7 cells. Appl Microbiol Biotechnol 2011;92: 115-124.
    • (2011) Appl Microbiol Biotechnol , vol.92 , pp. 115-124
    • Lei, M.1    Jiao, H.2    Liu, T.3
  • 26
    • 0030220818 scopus 로고    scopus 로고
    • Facilitation of apoptosis by autologous serum and related immunosuppression in the splenocyte culture
    • Kim HM, Oh GT, Hong DH, et al.: Facilitation of apoptosis by autologous serum and related immunosuppression in the splenocyte culture. Immunopharmacology 1996;34:39-50.
    • (1996) Immunopharmacology , vol.34 , pp. 39-50
    • Kim, H.M.1    Oh, G.T.2    Hong, D.H.3
  • 27
    • 0035107113 scopus 로고    scopus 로고
    • Alternative activation of antigen-presenting cells: Concepts and clinical relevance
    • Birk RW, Gratchev A, Hakiy N, et al.: Alternative activation of antigen-presenting cells: Concepts and clinical relevance. Hautarzt 2001;52:193-200.
    • (2001) Hautarzt , vol.52 , pp. 193-200
    • Birk, R.W.1    Gratchev, A.2    Hakiy, N.3
  • 28
    • 0035133989 scopus 로고    scopus 로고
    • Role of leukocytes and endothelial cells in the development of angiogenesis in inflammation and wound healing
    • Lingen MW: Role of leukocytes and endothelial cells in the development of angiogenesis in inflammation and wound healing. Arch Pathol Lab Med 2001;125:67-71.
    • (2001) Arch Pathol Lab Med , vol.125 , pp. 67-71
    • Lingen, M.W.1
  • 30
    • 0032112892 scopus 로고    scopus 로고
    • Polysaccharides of flower plants: Structure and physiological activity
    • Ovodov I: Polysaccharides of flower plants: Structure and physiological activity. Bioorg Khim 1998;24:483-501.
    • (1998) Bioorg Khim , vol.24 , pp. 483-501
    • Ovodov, I.1
  • 31
    • 0032061963 scopus 로고    scopus 로고
    • Anticarcinogenic effect of palustran on development of tumors induced by 3-(1-A-L-arabinopyranosyl)-1-methyl-1-nitrosourea (AMNU) in rats
    • Sherenesheva NI, Fin'ko VE, Blanko FF, et al.: Anticarcinogenic effect of palustran on development of tumors induced by 3-(1-A-L-arabinopyranosyl)-1-methyl-1-nitrosourea (AMNU) in rats. Biull Eksp Biol Med 1998;125:566-568.
    • (1998) Biull Eksp Biol Med , vol.125 , pp. 566-568
    • Sherenesheva, N.I.1    Fin'Ko, V.E.2    Blanko, F.F.3
  • 33
    • 31044440131 scopus 로고    scopus 로고
    • Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential
    • Schepetkin IA, Quinn MT: Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential. Int Immunopharmacol 2006;6:317-333.
    • (2006) Int Immunopharmacol , vol.6 , pp. 317-333
    • Schepetkin, I.A.1    Quinn, M.T.2
  • 34
    • 33646534388 scopus 로고    scopus 로고
    • Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264
    • Rhule A, Navarro S, Smith JR, Shepherd DM: Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells. J Ethnopharmacol 2006;106:121-128.
    • (2006) 7 Cells. J Ethnopharmacol , vol.106 , pp. 121-128
    • Rhule, A.1    Navarro, S.2    Smith, J.R.3    Shepherd, D.M.4
  • 35
    • 84917742004 scopus 로고    scopus 로고
    • Abelmoschus esculentus
    • (Lim TK, ed.) Springer Science+Business Media B.V., Dordrecht, Netherlands
    • Lim TK: Abelmoschus esculentus. In: Edible Medicinal and Non-Medicinal Plants, Vol. 3. (Lim TK, ed.) Springer Science+Business Media B.V., Dordrecht, Netherlands, 2013, pp. 160-167.
    • (2013) Edible Medicinal and Non-Medicinal Plants , vol.3 , pp. 160-167
    • Lim, T.K.1
  • 36
    • 0030694038 scopus 로고    scopus 로고
    • Biosynthesis and action of nitric oxide in mammalian cells
    • Mayer B, Hemmens B: Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 1997;22:477-481.
    • (1997) Trends Biochem Sci , vol.22 , pp. 477-481
    • Mayer, B.1    Hemmens, B.2
  • 37
    • 19444385661 scopus 로고    scopus 로고
    • Macrophage activation by polysaccharide isolated from Astragalus membranaceus
    • Lee KY, Jeon YJ: Macrophage activation by polysaccharide isolated from Astragalus membranaceus. Int Immunopharmacol 2005;5:1225-1233.
    • (2005) Int Immunopharmacol , vol.5 , pp. 1225-1233
    • Lee, K.Y.1    Jeon, Y.J.2
  • 38
    • 77955663860 scopus 로고    scopus 로고
    • Effects of astragalus polysaccharide on the immune response to foot-and-mouth disease vaccine in mice
    • Zhang NW, Li JF, Hu YX: Effects of astragalus polysaccharide on the immune response to foot-and-mouth disease vaccine in mice. Carbohydr Polym 2010;82:680-686.
    • (2010) Carbohydr Polym , vol.82 , pp. 680-686
    • Zhang, N.W.1    Li, J.F.2    Hu, Y.X.3
  • 41
    • 84898813390 scopus 로고    scopus 로고
    • Purification, characterization and immunomodulating activity of a polysaccharide from flowers of Abelmoschus esculentus
    • Zheng W, Zhao T, Feng W, et al.: Purification, characterization and immunomodulating activity of a polysaccharide from flowers of Abelmoschus esculentus. Carbohydr Polym 2014;106:335-342.
    • (2014) Carbohydr Polym , vol.106 , pp. 335-342
    • Zheng, W.1    Zhao, T.2    Feng, W.3
  • 42
    • 80054038374 scopus 로고    scopus 로고
    • Characterization of polysaccharide from Astragalus radix as the macrophage stimulator
    • Zhao LH, Ma ZX, Zhu J, Yu XH, Weng DP: Characterization of polysaccharide from Astragalus radix as the macrophage stimulator. Cell Immunol 2011;271:329-334.
    • (2011) Cell Immunol , vol.271 , pp. 329-334
    • Zhao, L.H.1    Ma, Z.X.2    Zhu, J.3    Yu, X.H.4    Weng, D.P.5
  • 43
    • 0034662482 scopus 로고    scopus 로고
    • Development of semisynthetic triterpenoid saponin derivatives with immune stimulating activity
    • Marciani DJ, Press JB, Reynolds RC, et al.: Development of semisynthetic triterpenoid saponin derivatives with immune stimulating activity. Vaccine 2000;18:3141-3151.
    • (2000) Vaccine , vol.18 , pp. 3141-3151
    • Marciani, D.J.1    Press, J.B.2    Reynolds, R.C.3
  • 44
    • 84869229456 scopus 로고    scopus 로고
    • Preparation, preliminary characterization and immunostimulatory activity of polysaccharide fractions from the peduncles of Hovenia dulcis
    • Wang M, Jiang C, Ma L, et al.: Preparation, preliminary characterization and immunostimulatory activity of polysaccharide fractions from the peduncles of Hovenia dulcis. Food Chem 2013;138:41-47.
    • (2013) Food Chem , vol.138 , pp. 41-47
    • Wang, M.1    Jiang, C.2    Ma, L.3
  • 45
    • 0031686828 scopus 로고    scopus 로고
    • Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai
    • Han SB, Kim YH, Lee CW, et al.: Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai. Immunopharmacology 1998;40:39-48.
    • (1998) Immunopharmacology , vol.40 , pp. 39-48
    • Han, S.B.1    Kim, Y.H.2    Lee, C.W.3
  • 46
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL: TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 47
    • 19944399370 scopus 로고    scopus 로고
    • Structural and immunological studies of a pectin and a pectic arabinogalactan from Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae)
    • Nergard CS, Matsumoto T, Inngjerdingen M, et al.: Structural and immunological studies of a pectin and a pectic arabinogalactan from Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae). Carbohydr Res 2005;340:115-130.
    • (2005) Carbohydr Res , vol.340 , pp. 115-130
    • Nergard, C.S.1    Matsumoto, T.2    Inngjerdingen, M.3
  • 48
    • 84872819964 scopus 로고    scopus 로고
    • Structure elucidation and immunological activity of a novel pectic polysaccharide from the stems of Avicennia marina
    • Fang X, Chen X: Structure elucidation and immunological activity of a novel pectic polysaccharide from the stems of Avicennia marina. Eur Food Res Technol 2013;236:243-248.
    • (2013) Eur Food Res Technol , vol.236 , pp. 243-248
    • Fang, X.1    Chen, X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.