Fully Automated Sample Preparation for Ultrafast N-Glycosylation Analysis of Antibody Therapeutics

Journal of Laboratory Automation

Volumn 21, Issue 2, 2016, Pages 281-286

  Szigeti, Marton ^a   Lew, Clarence ^b   Roby, Keith ^b   Guttman, Andras ^a,c  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b MDS SCIEX   (Canada)

^c UNIVERSITY OF PANNONIA   (Hungary)

Author keywords

antibody therapeutics; automation; capillary electrophoresis; magnetic beads; N glycosylation

Indexed keywords

AUTOMATION; BIOACTIVITY; CAPILLARY ELECTROPHORESIS; CENTRIFUGATION; FLUOROPHORES; GLYCOSYLATION; MAGNETISM; POLYSACCHARIDES; THROUGHPUT;

ANTIBODY THERAPEUTICS; BIOLOGICAL SIGNIFICANCE; BIOPHARMACEUTICAL INDUSTRY; CAPILLARY ELECTROPHORESIS ANALYSIS; MAGNETIC BEADS; N-GLYCOSYLATION; SAMPLE PREPARATION; THERAPEUTIC ANTIBODIES;

ANTIBODIES;

ACETIC ACID; ADALIMUMAB; ANTIBODY CONJUGATE; GLYCAN; GLYCOPROTEIN; IMMUNOGLOBULIN G; N ACETYL BETA GLUCOSAMINIDASE; TRASTUZUMAB; ANTIBODY; BIOLOGICAL PRODUCT; FLUORESCENT DYE; MICROSPHERE; POLYSACCHARIDE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CELL MEDIATED CYTOTOXICITY; CENTRIFUGATION; DEGLYCOSYLATION; GLYCOSYLATION; LASER FLUORESCENCE DEVICE; MEASUREMENT REPEATABILITY; N GLYCOSYLATION; CHEMISTRY; LABORATORY AUTOMATION; MAGNETISM; PHARMACEUTICS; PROCEDURES; SPECIMEN HANDLING; STAINING; TIME FACTOR;

ANTIBODIES; AUTOMATION, LABORATORY; BIOLOGICAL PRODUCTS; BIOPHARMACEUTICS; ELECTROPHORESIS, CAPILLARY; FLUORESCENT DYES; GLYCOPROTEINS; MAGNETICS; MICROSPHERES; POLYSACCHARIDES; SPECIMEN HANDLING; STAINING AND LABELING; TIME FACTORS;

EID: 84962541719     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068215608767     Document Type: Article

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