-
1
-
-
84892805731
-
Cancer statistics, 2014
-
24399786
-
Siegel R, Ma J, Zou Z, Jemal A (2014) Cancer statistics, 2014. CA Cancer J Clin 64:9-29. doi: 10. 3322/caac.21208 PMID: 24399786
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
3
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
20299480
-
Bodmer M, Meier C, Krahenbuhl S, Jick SS, Meier CR (2010) Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 33:1304-1308. doi: 10.2337/dc09-1791 PMID: 20299480
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krahenbuhl, S.3
Jick, S.S.4
Meier, C.R.5
-
4
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
16443869
-
Bowker SL, Majumdar SR, Veugelers P, Johnson JA (2006) Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care 29:254-258. PMID: 16443869
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
5
-
-
67650169923
-
Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease
-
19469001
-
Donadon V, Balbi M, Ghersetti M, Grazioli S, Perciaccante A, Della Valentina G, et al. (2009) Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease. World J Gastroenterol 15:2506-2511. PMID: 19469001
-
(2009)
World J Gastroenterol
, vol.15
, pp. 2506-2511
-
-
Donadon, V.1
Balbi, M.2
Ghersetti, M.3
Grazioli, S.4
Perciaccante, A.5
Della Valentina, G.6
-
6
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
15849206
-
Evans JM, Donnelly LA, Emslie-Smith AM, Alessi DR, Morris AD (2005) Metformin and reduced risk of cancer in diabetic patients. BMJ 330:1304-1305. PMID: 15849206
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
7
-
-
84876991747
-
Type 2 diabetes mellitus and pancreatic cancer
-
23632148
-
McAuliffe JC, Christein JD (2013) Type 2 diabetes mellitus and pancreatic cancer. Surg Clin North Am 93:619-627. doi: 10.1016/j.suc.2013.02.003 PMID: 23632148
-
(2013)
Surg Clin North Am
, vol.93
, pp. 619-627
-
-
McAuliffe, J.C.1
Christein, J.D.2
-
8
-
-
70350583054
-
Metformin use and prostate cancer in Caucasian men: Results from a populationbased case-control study
-
19653109
-
Wright JL, Stanford JL (2009) Metformin use and prostate cancer in Caucasian men: results from a populationbased case-control study. Cancer Causes Control 20:1617-1622. doi: 10.1007/s10552-009-9407-y PMID: 19653109
-
(2009)
Cancer Causes Control
, vol.20
, pp. 1617-1622
-
-
Wright, J.L.1
Stanford, J.L.2
-
9
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
19572116
-
Currie CJ, Poole CD, Gale EA (2009) The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 52:1766-1777. doi: 10.1007/s00125-009-1440-6 PMID: 19572116
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
10
-
-
77951006620
-
Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
-
20166205
-
Hassan MM, Curley SA, Li D, Kaseb A, Davila M, Abdalla EK, et al. (2010) Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma. Cancer 116:1938-1946. doi: 10.1002/cncr.24982 PMID: 20166205
-
(2010)
Cancer
, vol.116
, pp. 1938-1946
-
-
Hassan, M.M.1
Curley, S.A.2
Li, D.3
Kaseb, A.4
Davila, M.5
Abdalla, E.K.6
-
11
-
-
75149179169
-
Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16
-
19918015
-
Landman GW, Kleefstra N, van Hateren KJ, Groenier KH, Gans RO, Bilo HJ (2010) Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16. Diabetes Care 33:322-326. doi: 10. 2337/dc09-1380 PMID: 19918015
-
(2010)
Diabetes Care
, vol.33
, pp. 322-326
-
-
Landman, G.W.1
Kleefstra, N.2
Van Hateren, K.J.3
Groenier, K.H.4
Gans, R.O.5
Bilo, H.J.6
-
12
-
-
67650945180
-
Antidiabetic therapies affect risk of pancreatic cancer
-
19375425
-
Li D, Yeung SC, Hassan MM, Konopleva M, Abbruzzese JL (2009) Antidiabetic therapies affect risk of pancreatic cancer. Gastroenterology 137:482-488. doi: 10.1053/j.gastro.2009.04.013 PMID: 19375425
-
(2009)
Gastroenterology
, vol.137
, pp. 482-488
-
-
Li, D.1
Yeung, S.C.2
Hassan, M.M.3
Konopleva, M.4
Abbruzzese, J.L.5
-
13
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
19564453
-
Libby G, Donnelly LA, Donnan PT, Alessi DR, Morris AD, Evans JM (2009) New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 32:1620-1625. doi: 10.2337/dc08-2175 PMID: 19564453
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
14
-
-
78651451726
-
Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: A representative population prospective cohort study of 800, 000 individuals
-
21241523
-
Lee MS, Hsu CC, Wahlqvist ML, Tsai HN, Chang YH, Huang YC (2011) Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800, 000 individuals. BMC Cancer 11:20. doi: 10.1186/1471-2407-11-20 PMID: 21241523
-
(2011)
BMC Cancer
, vol.11
, pp. 20
-
-
Lee, M.S.1
Hsu, C.C.2
Wahlqvist, M.L.3
Tsai, H.N.4
Chang, Y.H.5
Huang, Y.C.6
-
15
-
-
84861127026
-
Metformin use is associated with better survival of diabetic patients with pancreatic cancer
-
22465831
-
Sadeghi N, Abbruzzese JL, Yeung SC, Hassan M, Li D (2012) Metformin use is associated with better survival of diabetic patients with pancreatic cancer. Clin Cancer Res 18:2905-2912. doi: 10.1158/1078-0432. CCR-11-2994 PMID: 22465831
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2905-2912
-
-
Sadeghi, N.1
Abbruzzese, J.L.2
Yeung, S.C.3
Hassan, M.4
Li, D.5
-
16
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
15261145
-
Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, et al. (2004) The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 6:91-99. PMID: 15261145
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
DePinho, R.A.6
-
17
-
-
34347220473
-
Defining the role of mTOR in cancer
-
17613433
-
Guertin DA, Sabatini DM (2007) Defining the role of mTOR in cancer. Cancer Cell 12:9-22. PMID: 17613433
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
18
-
-
77955592753
-
Diabetes mellitus in pancreatic cancer and the need for diagnosis of asymptomatic disease
-
20720443
-
Bartosch-Harlid A, Andersson R (2010) Diabetes mellitus in pancreatic cancer and the need for diagnosis of asymptomatic disease. Pancreatology 10:423-428. doi: 10.1159/000264676 PMID: 20720443
-
(2010)
Pancreatology
, vol.10
, pp. 423-428
-
-
Bartosch-Harlid, A.1
Andersson, R.2
-
19
-
-
57749175173
-
New-onset diabetes: A potential clue to the early diagnosis of pancreatic cancer
-
19111249
-
Pannala R, Basu A, Petersen GM, Chari ST (2009) New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer. Lancet Oncol 10:88-95. doi: 10.1016/S1470-2045 (08) 70337-1 PMID: 19111249
-
(2009)
Lancet Oncol
, vol.10
, pp. 88-95
-
-
Pannala, R.1
Basu, A.2
Petersen, G.M.3
Chari, S.T.4
-
20
-
-
71449120059
-
Insulin resistance and hyperinsulinaemia in the development and progression of cancer
-
Godsland IF (2010) Insulin resistance and hyperinsulinaemia in the development and progression of cancer. Clin Sci (Lond) 118:315-332.
-
(2010)
Clin Sci (Lond)
, vol.118
, pp. 315-332
-
-
Godsland, I.F.1
-
21
-
-
0030669557
-
Insulin resistance and promotion of aberrant crypt foci in the colons of rats on a high-fat diet
-
9383787
-
Koohestani N, Tran TT, Lee W, Wolever TM, Bruce WR (1997) Insulin resistance and promotion of aberrant crypt foci in the colons of rats on a high-fat diet. Nutr Cancer 29:69-76. PMID: 9383787
-
(1997)
Nutr Cancer
, vol.29
, pp. 69-76
-
-
Koohestani, N.1
Tran, T.T.2
Lee, W.3
Wolever, T.M.4
Bruce, W.R.5
-
23
-
-
44849099894
-
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
-
18212742
-
Ben Sahra I, Laurent K, Loubat A, Giorgetti-Peraldi S, Colosetti P, Auberger P, et al. (2008) The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene 27:3576-3586. doi: 10.1038/sj.onc.1211024 PMID: 18212742
-
(2008)
Oncogene
, vol.27
, pp. 3576-3586
-
-
Ben Sahra, I.1
Laurent, K.2
Loubat, A.3
Giorgetti-Peraldi, S.4
Colosetti, P.5
Auberger, P.6
-
24
-
-
34547114031
-
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
-
17638885
-
Buzzai M, Jones RG, Amaravadi RK, Lum JJ, DeBerardinis RJ, Zhao F, et al. (2007) Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Res 67:6745-6752. PMID: 17638885
-
(2007)
Cancer Res
, vol.67
, pp. 6745-6752
-
-
Buzzai, M.1
Jones, R.G.2
Amaravadi, R.K.3
Lum, J.J.4
DeBerardinis, R.J.5
Zhao, F.6
-
25
-
-
79953685303
-
The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth
-
20455996
-
Feng YH, Velazquez-Torres G, Gully C, Chen J, Lee MH, Yeung SC (2011) The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth. J Cell Mol Med 15:825-836. doi: 10.1111/j.1582-4934.2010.01083.x PMID: 20455996
-
(2011)
J Cell Mol Med
, vol.15
, pp. 825-836
-
-
Feng, Y.H.1
Velazquez-Torres, G.2
Gully, C.3
Chen, J.4
Lee, M.H.5
Yeung, S.C.6
-
26
-
-
69249162223
-
Metformin disrupts crosstalk between G proteincoupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth
-
19679549
-
Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E (2009) Metformin disrupts crosstalk between G proteincoupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Res 69:6539-6545. doi: 10.1158/0008-5472. CAN-09-0418 PMID: 19679549
-
(2009)
Cancer Res
, vol.69
, pp. 6539-6545
-
-
Kisfalvi, K.1
Eibl, G.2
Sinnett-Smith, J.3
Rozengurt, E.4
-
27
-
-
33751284806
-
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
-
17062558
-
Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M (2006) Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res 66:10269-10273. PMID: 17062558
-
(2006)
Cancer Res
, vol.66
, pp. 10269-10273
-
-
Zakikhani, M.1
Dowling, R.2
Fantus, I.G.3
Sonenberg, N.4
Pollak, M.5
-
28
-
-
77951708711
-
Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: A novel target for the antidiabetic drug metformin in pancreatic cancer
-
20388847
-
Rozengurt E, Sinnett-Smith J, Kisfalvi K (2010) Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clin Cancer Res 16:2505-2511. doi: 10.1158/1078-0432. CCR-09-2229 PMID: 20388847
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2505-2511
-
-
Rozengurt, E.1
Sinnett-Smith, J.2
Kisfalvi, K.3
-
29
-
-
84962559485
-
Mechanism of Metformin-dependent Inhibition of mTOR and Ras Activity in Pancreatic Cancer: Role of Sp Transcription Factors
-
Nair V, Sreevalsan S, Basha R, Abdelrahim M, Abudayyeh A, Rodrigues Hoffman A, et al. (2014) Mechanism of Metformin-dependent Inhibition of mTOR and Ras Activity in Pancreatic Cancer: Role of Sp Transcription Factors. J Biol Chem.
-
(2014)
J Biol Chem.
-
-
Nair, V.1
Sreevalsan, S.2
Basha, R.3
Abdelrahim, M.4
Abudayyeh, A.5
Rodrigues Hoffman, A.6
-
30
-
-
84975152214
-
PlGF/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity
-
Incio J, Tam J, Rahbari NN, Suboj P, McManus DT, Chin SM, et al. (2016) PlGF/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity. Clin Cancer Res.
-
(2016)
Clin Cancer Res.
-
-
Incio, J.1
Tam, J.2
Rahbari, N.N.3
Suboj, P.4
McManus, D.T.5
Chin, S.M.6
-
31
-
-
84905194899
-
Chemotherapy and metformin in pancreatic adenocarcinoma and neuroendocrine tumors
-
25076330
-
Burney S, Khawaja KI, Saif MW, Masud F (2014) Chemotherapy and metformin in pancreatic adenocarcinoma and neuroendocrine tumors. JOP 15:313-316. doi: 10.6092/1590-8577/2677 PMID: 25076330
-
(2014)
JOP
, vol.15
, pp. 313-316
-
-
Burney, S.1
Khawaja, K.I.2
Saif, M.W.3
Masud, F.4
-
32
-
-
84962579181
-
(Ir) relevance of Metformin Treatment in Patients with Metastatic Pancreatic Cancer: An Open-Label, Randomized Phase II Trial
-
Reni M, Dugnani E, Cereda S, Belli C, Balzano G, Nicoletti R, et al. (2015) (Ir) relevance of Metformin Treatment in Patients with Metastatic Pancreatic Cancer: An Open-Label, Randomized Phase II Trial. Clin Cancer Res.
-
(2015)
Clin Cancer Res.
-
-
Reni, M.1
Dugnani, E.2
Cereda, S.3
Belli, C.4
Balzano, G.5
Nicoletti, R.6
|