메뉴 건너뛰기




Volumn 11, Issue 3, 2016, Pages

Human FGF-21 is a substrate of fibroblast activation protein

Author keywords

[No Author keywords available]

Indexed keywords

ARI 3099; FIBROBLAST ACTIVATION PROTEIN; FIBROBLAST GROWTH FACTOR 21; PROLYL ENDOPEPTIDASE; PROLYL ENDOPEPTIDASE INHIBITOR; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; GELATINASE; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; SEPRASE; SERINE PROTEINASE;

EID: 84962516266     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151269     Document Type: Article
Times cited : (55)

References (33)
  • 2
    • 79955590366 scopus 로고    scopus 로고
    • Hormone-like fibroblast growth factors and metabolic regulation
    • 21504790 Jul
    • Long YC, Kharitonenkov A. Hormone-like fibroblast growth factors and metabolic regulation. Biochim Biophys Acta. 2011 Jul; 1812(7):791-5. doi: 10.1016/j.bbadis.2011.04.002 PMID: 21504790
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.7 , pp. 791-795
    • Long, Y.C.1    Kharitonenkov, A.2
  • 3
    • 24644496774 scopus 로고    scopus 로고
    • An evolutionary history of the FGFsuperfamily
    • 16015590 Aug
    • Popovici C, Roubin R, Coulier F, Birnbaum D. An evolutionary history of the FGFsuperfamily. Bioessays. 2005 Aug; 27(8):849-57. PMID: 16015590
    • (2005) Bioessays , vol.27 , Issue.8 , pp. 849-857
    • Popovici, C.1    Roubin, R.2    Coulier, F.3    Birnbaum, D.4
  • 4
    • 70350322694 scopus 로고    scopus 로고
    • Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis
    • 19819944 Nov
    • Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology. 2009 Nov; 150(11):4931-40. doi: 10.1210/en. 2009-0532 PMID: 19819944
    • (2009) Endocrinology , vol.150 , Issue.11 , pp. 4931-4940
    • Badman, M.K.1    Koester, A.2    Flier, J.S.3    Kharitonenkov, A.4    Maratos-Flier, E.5
  • 5
    • 70349324370 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver
    • 19589869 Oct
    • Hotta Y, Nakamura H, Konishi M, Murata Y, Takagi H, Matsumura S, et al. Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver. Endocrinology. 2009 Oct; 150(10):4625-33. doi: 10.1210/en. 2009-0119 PMID: 19589869
    • (2009) Endocrinology , vol.150 , Issue.10 , pp. 4625-4633
    • Hotta, Y.1    Nakamura, H.2    Konishi, M.3    Murata, Y.4    Takagi, H.5    Matsumura, S.6
  • 6
    • 70350455732 scopus 로고    scopus 로고
    • Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models-association with liver and adipose tissue effects
    • 19706786 Nov
    • Xu J, Stanislaus S, Chinookoswong N, Lau YY, Hager T, Patel J, et al. Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models-association with liver and adipose tissue effects. Am J Physiol Endocrinol Metab. 2009 Nov; 297(5):E1105-14. doi: 10.1152/ajpendo.00348.2009 PMID: 19706786
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , Issue.5 , pp. E1105-E1114
    • Xu, J.1    Stanislaus, S.2    Chinookoswong, N.3    Lau, Y.Y.4    Hager, T.5    Patel, J.6
  • 7
    • 84883151328 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 improves insulin resistance and ameliorates renal injury in db/db mice
    • 23825123 Sep
    • Kim HW, Lee JE, Cha JJ, Hyun YY, Kim JE, Lee MH, et al. Fibroblast growth factor 21 improves insulin resistance and ameliorates renal injury in db/db mice. Endocrinology. 2013 Sep; 154(9):3366-76. doi: 10.1210/en. 2012-2276 PMID: 23825123
    • (2013) Endocrinology , vol.154 , Issue.9 , pp. 3366-3376
    • Kim, H.W.1    Lee, J.E.2    Cha, J.J.3    Hyun, Y.Y.4    Kim, J.E.5    Lee, M.H.6
  • 8
    • 84865442538 scopus 로고    scopus 로고
    • Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys
    • 22798348 Sep
    • Veniant MM, Komorowski R, Chen P, Stanislaus S, Winters K, Hager T, et al. Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys. Endocrinology. 2012 Sep; 153(9):4192-203. doi: 10.1210/en. 2012-1211 PMID: 22798348
    • (2012) Endocrinology , vol.153 , Issue.9 , pp. 4192-4203
    • Veniant, M.M.1    Komorowski, R.2    Chen, P.3    Stanislaus, S.4    Winters, K.5    Hager, T.6
  • 9
    • 33846418834 scopus 로고    scopus 로고
    • The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21
    • 17068132 Feb
    • Kharitonenkov A, Wroblewski VJ, Koester A, Chen YF, Clutinger CK, Tigno XT, et al. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21. Endocrinology. 2007 Feb; 148(2):774-81. PMID: 17068132
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 774-781
    • Kharitonenkov, A.1    Wroblewski, V.J.2    Koester, A.3    Chen, Y.F.4    Clutinger, C.K.5    Tigno, X.T.6
  • 10
    • 78049297991 scopus 로고    scopus 로고
    • Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
    • 20682689 Nov
    • Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, et al. Obesity is a fibroblast growth factor 21(FGF21)-resistant state. Diabetes. 2010 Nov; 59(11):2781-9. doi: 10.2337/db10-0193 PMID: 20682689
    • (2010) Diabetes , vol.59 , Issue.11 , pp. 2781-2789
    • Fisher, F.M.1    Chui, P.C.2    Antonellis, P.J.3    Bina, H.A.4    Kharitonenkov, A.5    Flier, J.S.6
  • 11
    • 84883481988 scopus 로고    scopus 로고
    • The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes
    • 24011069 Sep. 3
    • Gaich G, Chien JY, Fu H, Glass LC, Deeg MA, Holland WL, et al. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes. Cell Metab. 2013 Sep. 3;18(3):333-40. doi: 10. 1016/j.cmet.2013.08.005 PMID: 24011069
    • (2013) Cell Metab , vol.18 , Issue.3 , pp. 333-340
    • Gaich, G.1    Chien, J.Y.2    Fu, H.3    Glass, L.C.4    Deeg, M.A.5    Holland, W.L.6
  • 12
    • 84861657962 scopus 로고    scopus 로고
    • Fundamentals of FGF19&FGF21 action in vitro and in vivo
    • 22675463
    • Adams AC, Coskun T, Rovira AR, Schneider MA, Raches DW, Micanovic R, et al. Fundamentals of FGF19&FGF21 action in vitro and in vivo. PLoSOne. 2012;7(5):e38438. doi: 10.1371/journal.pone. 0038438 PMID: 22675463
    • (2012) PLoSOne , vol.7 , Issue.5 , pp. e38438
    • Adams, A.C.1    Coskun, T.2    Rovira, A.R.3    Schneider, M.A.4    Raches, D.W.5    Micanovic, R.6
  • 13
    • 48349146527 scopus 로고    scopus 로고
    • Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    • 18252893 May
    • Zhang X, Yeung DC, Karpisek M, Stejskal D, Zhou ZG, Liu F, et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes. 2008 May; 57(5):1246-53. doi: 10.2337/db07-1476 PMID: 18252893
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1246-1253
    • Zhang, X.1    Yeung, D.C.2    Karpisek, M.3    Stejskal, D.4    Zhou, Z.G.5    Liu, F.6
  • 14
    • 0034697846 scopus 로고    scopus 로고
    • Identification of a novel FGF, FGF-21, preferentially expressed in the liver
    • 10858549 Jun. 21
    • Nishimura T, Nakatake Y, Konishi M, Itoh N. Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim Biophys Acta. 2000 Jun. 21;1492(1):203-6. PMID: 10858549
    • (2000) Biochim Biophys Acta , vol.1492 , Issue.1 , pp. 203-206
    • Nishimura, T.1    Nakatake, Y.2    Konishi, M.3    Itoh, N.4
  • 15
    • 34247565954 scopus 로고    scopus 로고
    • Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
    • 17339340 May
    • Goetz R, Beenken A, Ibrahimi OA, Kalinina J, Olsen SK, Eliseenkova AV, et al. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol Cell Biol. 2007 May; 27(9):3417-28. PMID: 17339340
    • (2007) Mol Cell Biol , vol.27 , Issue.9 , pp. 3417-3428
    • Goetz, R.1    Beenken, A.2    Ibrahimi, O.A.3    Kalinina, J.4    Olsen, S.K.5    Eliseenkova, A.V.6
  • 16
    • 80053428117 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes
    • 21846717 Oct. 7
    • Ge X, Chen C, Hui X, Wang Y, Lam KS, Xu A. Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes. J Biol Chem. 2011 Oct. 7;286(40):34533-41. doi: 10.1074/jbc. M111.248591 PMID: 21846717
    • (2011) J Biol Chem , vol.286 , Issue.40 , pp. 34533-34541
    • Ge, X.1    Chen, C.2    Hui, X.3    Wang, Y.4    Lam, K.S.5    Xu, A.6
  • 17
    • 33750587755 scopus 로고    scopus 로고
    • Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways
    • 16936195 Sep
    • Wente W, Efanov AM, Brenner M, Kharitonenkov A, Koster A, Sandusky GE, et al. Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. Diabetes. 2006 Sep; 55(9):2470-8. PMID: 16936195
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2470-2478
    • Wente, W.1    Efanov, A.M.2    Brenner, M.3    Kharitonenkov, A.4    Koster, A.5    Sandusky, G.E.6
  • 18
    • 84881508008 scopus 로고    scopus 로고
    • The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
    • 23066506
    • Zhang Y, Xie Y, Berglund ED, Coate KC, He TT, Katafuchi T, et al. The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. Elife. 2012;1:e00065. doi: 10.7554/eLife.00065 PMID: 23066506
    • (2012) Elife , vol.1 , pp. e00065
    • Zhang, Y.1    Xie, Y.2    Berglund, E.D.3    Coate, K.C.4    He, T.T.5    Katafuchi, T.6
  • 19
    • 79960844094 scopus 로고    scopus 로고
    • The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes
    • 21664250 Aug. 6
    • Zhang Y, Lei T, Huang JF, Wang SB, Zhou LL, Yang ZQ, et al. The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes. Mol Cell Endocrinol. 2011 Aug. 6;342(1-2):41-7. doi: 10.1016/j.mce.2011.05.003 PMID: 21664250
    • (2011) Mol Cell Endocrinol , vol.342 , Issue.1-2 , pp. 41-47
    • Zhang, Y.1    Lei, T.2    Huang, J.F.3    Wang, S.B.4    Zhou, L.L.5    Yang, Z.Q.6
  • 20
    • 61649127208 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
    • 18840786 Jan
    • Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes. 2009 Jan; 58(1):250-9. doi: 10.2337/db08-0392 PMID: 18840786
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 250-259
    • Xu, J.1    Lloyd, D.J.2    Hale, C.3    Stanislaus, S.4    Chen, M.5    Sivits, G.6
  • 21
    • 84870278211 scopus 로고    scopus 로고
    • Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes
    • 23209571
    • Hecht R, Li YS, Sun J, Belouski E, Hall M, Hager T, et al. Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes. PLoSOne. 2012;7(11):e49345. doi: 10.1371/journal.pone.0049345 PMID: 23209571
    • (2012) PLoSOne , vol.7 , Issue.11 , pp. e49345
    • Hecht, R.1    Li, Y.S.2    Sun, J.3    Belouski, E.4    Hall, M.5    Hager, T.6
  • 22
    • 62149139387 scopus 로고    scopus 로고
    • Different roles of N- and C-termini in the functional activity of FGF21
    • 19117008 May
    • Micanovic R, Raches DW, Dunbar JD, Driver DA, Bina HA, Dickinson CD, et al. Different roles of N- and C-termini in the functional activity of FGF21. J Cell Physiol. 2009 May; 219(2):227-34. doi: 10. 1002/jcp. 21675 PMID: 19117008
    • (2009) J Cell Physiol , vol.219 , Issue.2 , pp. 227-234
    • Micanovic, R.1    Raches, D.W.2    Dunbar, J.D.3    Driver, D.A.4    Bina, H.A.5    Dickinson, C.D.6
  • 23
    • 79957846744 scopus 로고    scopus 로고
    • Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate
    • 21288888 Jun
    • Huang CH, Suen CS, Lin CT, Chien CH, Lee HY, Chung KM, et al. Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate. J Biochem. 2011 Jun; 149(6):685-92. doi: 10.1093/jb/mvr017 PMID: 21288888
    • (2011) J Biochem , vol.149 , Issue.6 , pp. 685-692
    • Huang, C.H.1    Suen, C.S.2    Lin, C.T.3    Chien, C.H.4    Lee, H.Y.5    Chung, K.M.6
  • 24
    • 84864285404 scopus 로고    scopus 로고
    • Comparative analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein alpha
    • 22750443 Jul. 30
    • Jambunathan K, Watson DS, Endsley AN, Kodukula K, Galande AK. Comparative analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein alpha. FEBS Lett. 2012 Jul. 30;586(16):2507-12. doi: 10.1016/j.febslet.2012.06.015 PMID: 22750443
    • (2012) FEBS Lett , vol.586 , Issue.16 , pp. 2507-2512
    • Jambunathan, K.1    Watson, D.S.2    Endsley, A.N.3    Kodukula, K.4    Galande, A.K.5
  • 25
    • 33646344722 scopus 로고    scopus 로고
    • Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity
    • 16410248 Mar. 17
    • Edosada CY, Quan C, Wiesmann C, Tran T, Sutherlin D, Reynolds M, et al. Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity. J Biol Chem. 2006 Mar. 17;281(11):7437-44. PMID: 16410248
    • (2006) J Biol Chem. , vol.281 , Issue.11 , pp. 7437-7444
    • Edosada, C.Y.1    Quan, C.2    Wiesmann, C.3    Tran, T.4    Sutherlin, D.5    Reynolds, M.6
  • 27
    • 84877690891 scopus 로고    scopus 로고
    • Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase
    • 23594271 May 9
    • Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, et al. Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a PMID: 23594271
    • (2013) J Med Chem. , vol.56 , Issue.9 , pp. 3467-3477
    • Poplawski, S.E.1    Lai, J.H.2    Li, Y.3    Jin, Z.4    Liu, Y.5    Wu, W.6
  • 28
    • 84890386346 scopus 로고    scopus 로고
    • Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs
    • 24371721
    • Keane FM, Yao TW, Seelk S, Gall MG, Chowdhury S, Poplawski SE, et al. Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs. FEBS Open Bio. 2013;4:43-54. doi: 10.1016/j.fob.2013.12.001 PMID: 24371721
    • (2013) FEBS Open Bio. , vol.4 , pp. 43-54
    • Keane, F.M.1    Yao, T.W.2    Seelk, S.3    Gall, M.G.4    Chowdhury, S.5    Poplawski, S.E.6
  • 29
    • 64549152937 scopus 로고    scopus 로고
    • Serum levels of the adipokine FGF21 depend on renal function
    • 18840768 Jan
    • Stein S, Bachmann A, Lossner U, Kratzsch J, Bluher M, Stumvoll M, et al. Serum levels of the adipokine FGF21 depend on renal function. Diabetes Care. 2009 Jan; 32(1):126-8. doi: 10.2337/dc08-1054 PMID: 18840768
    • (2009) Diabetes Care. , vol.32 , Issue.1 , pp. 126-128
    • Stein, S.1    Bachmann, A.2    Lossner, U.3    Kratzsch, J.4    Bluher, M.5    Stumvoll, M.6
  • 30
    • 84874903440 scopus 로고    scopus 로고
    • Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319
    • 23536797
    • Kharitonenkov A, Beals JM, Micanovic R, Strifler BA, Rathnachalam R, Wroblewski VJ, et al. Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. PLoSOne. 2013;8(3):e58575. doi: 10.1371/journal.pone.0058575 PMID: 23536797
    • (2013) PLoSOne. , vol.8 , Issue.3 , pp. e58575
    • Kharitonenkov, A.1    Beals, J.M.2    Micanovic, R.3    Strifler, B.A.4    Rathnachalam, R.5    Wroblewski, V.J.6
  • 31
    • 57849155278 scopus 로고    scopus 로고
    • FGF21 N- and C-termini play different roles in receptor interaction and activation
    • 19059246 Jan 5
    • Yie J, Hecht R, Patel J, Stevens J, Wang W, Hawkins N, et al. FGF21 N- and C-termini play different roles in receptor interaction and activation. FEBS Lett. 2009 Jan 5;583(1):19-24. doi: 10.1016/j. febslet.2008.11.023 PMID: 19059246
    • (2009) FEBS Lett. , vol.583 , Issue.1 , pp. 19-24
    • Yie, J.1    Hecht, R.2    Patel, J.3    Stevens, J.4    Wang, W.5    Hawkins, N.6
  • 32


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.