Differential association of generalized and abdominal obesity with diabetic retinopathy in Asian patients with type 2 diabetes

JAMA Ophthalmology

Volumn 134, Issue 3, 2016, Pages 251-257

  Man, Ryan Eyn Kidd ^a   Sabanayagam, Charumathi ^a,b   Chiang, Peggy Pei Chia ^c   Li, Ling Jun ^a,b   Noonan, Jonathan Edward ^d   Wang, Jie Jin ^e   Wong, Tien Yin ^a,b,f   Cheung, Gemmy Chui Ming ^f   Tan, Gavin Siew Wei ^f   Lamoureux, Ecosse L ^a,b,d  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

^f SINGAPORE NATIONAL EYE CENTRE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL OBESITY; ADULT; ARTICLE; ASIAN; BODY HEIGHT; BODY MASS; BODY WEIGHT; CROSS-SECTIONAL STUDY; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; DISEASE SEVERITY; ETHNICITY; FEMALE; HIP CIRCUMFERENCE; HUMAN; MACULAR THICKNESS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR; SINGAPORE; WAIST CIRCUMFERENCE; WAIST HIP RATIO; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; EPIDEMIOLOGY; ETHNOLOGY; MACULAR EDEMA; MIDDLE AGED; OBESITY; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PATHOPHYSIOLOGY; RETINA;

GLYCOSYLATED HEMOGLOBIN;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MACULAR EDEMA; MALE; MIDDLE AGED; OBESITY; OBESITY, ABDOMINAL; RETINA; RISK FACTORS; SINGAPORE; TOMOGRAPHY, OPTICAL COHERENCE; WAIST-HIP RATIO;

EID: 84962423425     PISSN: 21686165     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2015.5103     Document Type: Article

References (36)

1. Saaddine JB, Honeycutt AA, Narayan KM, Zhang X, Klein R, Boyle JP. Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005-2050. Arch Ophthalmol. 2008; 126(12): 1740-1747.
2. Yau JW, Rogers SL, Kawasaki R, et al.; Meta-Analysis for Eye Disease (META-EYE) Study Group. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012; 35(3): 556-564.
3. Younis N, Broadbent DM, Vora JP, Harding SP; Liverpool Diabetic Eye Study. Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study. Lancet. 2003; 361(9353): 195-200.
4. Ministry of Health. National Health Survey 2010. http://www.moh.gov.sg/content/moh-web/home/Publications/Reports/2011/national-health-survey2010.html. January 16, 2014.
5. Vazquez G, Duval S, Jacobs DR Jr, Silventoinen K. Comparison of body mass index, waist circumference, and waist/hip ratio in predicting incident diabetes: a meta-analysis. Epidemiol Rev. 2007; 29: 115-128.
6. Nguyen NT, Nguyen XM, Lane J, Wang P. Relationship between obesity and diabetes in a US adult population: findings from the National Health and Nutrition Examination Survey, 1999-2006. Obes Surg. 2011; 21(3): 351-355.
7. Cheung N, Mitchell P, Wong TY. Diabetic retinopathy. Lancet. 2010; 376(9735): 124-136.
8. World Health Organization. Obesity and overweight. http://www.who.int/mediacentre/factsheets/fs311/en/. Accessed February 20, 2015.
9. van Leiden HA, Dekker JM, Moll AC, et al. Blood pressure, lipids, and obesity are associated with retinopathy: the Hoorn Study. Diabetes Care. 2002; 25(8): 1320-1325.
10. Rooney D, Lye WK, Tan G, et al. Body mass index and retinopathy in Asian populations with diabetes mellitus. Acta Diabetol. 2015; 52(1): 73-80.
11. Wong TY, Klein R, Islam FM, et al. Diabetic retinopathy in a multi-ethnic cohort in the United States. Am J Ophthalmol. 2006; 141(3): 446-455.
12. Dowse GK, Humphrey AR, Collins VR, et al. Prevalence and risk factors for diabetic retinopathy in the multiethnic population of Mauritius. Am J Epidemiol. 1998; 147(5): 448-457.
13. Jabbar A, Irfanullah A, Akhter J, Mirza YK. Dyslipidemia and its relation with body mass index versus waist hip ratio. J Pak Med Assoc. 1997; 47(12): 308-310.
14. Brown CD, Higgins M, Donato KA, et al. Body mass index and the prevalence of hypertension and dyslipidemia. Obes Res. 2000; 8(9): 605-619.
15. Egbe EO, Asuquo OA, Ekwere EO, Olufemi F, Ohwovoriole AE. Assessment of anthropometric indices among residents of Calabar, South-East Nigeria. Indian J Endocrinol Metab. 2014; 18(3): 386-393.
16. Brooke P, Bullock R. Validation of a 6 item cognitive impairment test with a view to primary care usage. Int J Geriatr Psychiatry. 1999; 14(11): 936-940.
17. Consultation WHOE; WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004; 363(9403): 157-163.
18. Yeo CP, Tan CH, Jacob E. Haemoglobin A1c: evaluation of a new HbA1c point-of-care analyser Bio-Rad in2it in comparison with the DCA 2000 and central laboratory analysers. Ann Clin Biochem. 2009; 46(pt 5): 373-376.
19. Millán J, Pintó X, Muñoz A, et al. Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention. Vasc Health Risk Manag. 2009; 5: 757-765.
20. Pang C, Jia L, Jiang S, et al. Determination of diabetic retinopathy prevalence and associated risk factors in Chinese diabetic and pre-diabetic subjects: Shanghai Diabetic Complications Study. Diabetes Metab Res Rev. 2012; 28(3): 276-283.
21. Lim LS, Tai ES, Mitchell P, et al. C-reactive protein, body mass index, and diabetic retinopathy. Invest Ophthalmol Vis Sci. 2010; 51(9): 4458-4463.
22. Fujimoto WY, Abbate SL, Kahn SE, Hokanson JE, Brunzell JD. The visceral adiposity syndrome in Japanese-American men. Obes Res. 1994; 2(4): 364-371.
23. Panagiotakos DB, Pitsavos C, Yannakoulia M, Chrysohoou C, Stefanadis C. The implication of obesity and central fat on markers of chronic inflammation: the ATTICA Study. Atherosclerosis. 2005; 183(2): 308-315.
24. Anan F, Takayuki M, Takahashi N, et al. Diabetic retinopathy is associated with insulin resistance and cardiovascular autonomic dysfunction in type 2 diabetic patients. Hypertens Res. 2009; 32(4): 299-305.
25. El-Asrar AM. Role of inflammation in the pathogenesis of diabetic retinopathy. Middle East Afr J Ophthalmol. 2012; 19(1): 70-74.
26. Chaturvedi N, Sjoelie AK, Porta M, et al.; EURODIAB Prospective Complications Study. Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes. Diabetes Care. 2001; 24(2): 284-289.
27. Maneschi F, Mashiter K, Kohner EM. Insulin resistance and insulin deficiency in diabetic retinopathy of non-insulin-dependent diabetes. Diabetes. 1983; 32(1): 82-87.
28. Ruderman N, Chisholm D, Pi-Sunyer X, Schneider S. The metabolically obese, normal-weight individual revisited. Diabetes. 1998; 47(5): 699-713.
29. Deepa M, Farooq S, Deepa R, Manjula D, Mohan V. Prevalence and significance of generalized and central body obesity in an urban Asian Indian population in Chennai, India (CURES: 47). Eur J Clin Nutr. 2009; 63(2): 259-267.
30. Pan WH, Cedres LB, Liu K, et al. Relationship of clinical diabetes and asymptomatic hyperglycemia to risk of coronary heart disease mortality in men and women. Am J Epidemiol. 1986; 123(3): 504-516.
31. Lundberg V, Stegmayr B, Asplund K, Eliasson M, Huhtasaari F. Diabetes as a risk factor for myocardial infarction: population and gender perspectives. J Intern Med. 1997; 241(6): 485-492.
32. Després JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature. 2006; 444(7121): 881-887.
33. Benarous R, Sasongko MB, Qureshi S, et al. Differential association of serum lipids with diabetic retinopathy and diabetic macular edema. Invest Ophthalmol Vis Sci. 2011; 52(10): 7464-7469.
34. Man RE, Sasongko MB, Wang JJ, et al. The association of estimated glomerular filtration rate with diabetic retinopathy and macular edema. Invest Ophthalmol Vis Sci. 2015; 56(8): 4810-4816.
35. DeFronzo RA, Bonadonna RC, Ferrannini E. Pathogenesis of NIDDM: a balanced overview. Diabetes Care. 1992; 15(3): 318-368.
36. Atkinson MA, Eisenbarth GS. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet. 2001; 358(9277): 221-229.