Hygiene Hypothesis: Is the Evidence the Same All over the World?

Digestive Diseases

Volumn 34, Issue 1-2, 2016, Pages 35-42

  Leong, Rupert W ^a   Mitrev, Nikola ^a   Ko, Yanna ^a  

^a ANZAC Research Institute   (Australia)

Author keywords

Autoimmune; Colitis; Crohn; Hygiene; Hypothesis

Indexed keywords

CONFERENCE PAPER; DEVELOPING COUNTRY; ENVIRONMENTAL FACTOR; HUMAN; HYGIENE HYPOTHESIS; INDUSTRIALIZATION; INFLAMMATORY BOWEL DISEASE; INTESTINE FLORA; MIGRATION; NONHUMAN; PRIORITY JOURNAL; AUSTRALIA; CASE CONTROL STUDY; EVIDENCE BASED MEDICINE; GLOBAL HEALTH; HYGIENE; IMMUNOLOGY; INCIDENCE; INFLAMMATORY BOWEL DISEASES; PROCEDURES; RISK FACTOR; STANDARDS; TRENDS;

AUSTRALIA; CASE-CONTROL STUDIES; DEVELOPING COUNTRIES; EVIDENCE-BASED MEDICINE; GLOBAL HEALTH; HUMANS; HYGIENE; HYGIENE HYPOTHESIS; INCIDENCE; INFLAMMATORY BOWEL DISEASES; RISK FACTORS;

EID: 84962376505     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000442922     Document Type: Conference Paper

References (41)

1. Gearry RB, Leong RW: Inflammatory bowel disease in Asia: The start of the epidemic? J Gastroenterol Hepatol 2013; 28: 899-900.
2. Leong RW, Huang T, Ko Y, Jeon A, Chang J, Kohler F, Kariyawasam V: Prospective validation study of the international classification of functioning, disability and health score in Crohn's disease and ulcerative colitis. J Crohns Colitis 2014; 8: 1237-1245.
3. Selinger CP, Andrews J, Dent OF, Norton I, Jones B, McDonald C, Cowlishaw J, Barr G, Selby W, Leong RW; Sydney IBD Cohort Study Group: Cause-specific mortality and 30-year relative survival of Crohn's disease and ulcerative colitis. Inflamm Bowel Dis 2013; 19: 1880-1888.
4. Ooi CJ, Hilmi I, Makharia GK, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, Sollano J, Manatsathit S, de Silva HJ, Rerknimitr R, Pisespongsa P, Abu Hassan MR, Sung J, Hibi T, Boey CC, Moran N, Leong RW; Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease: The Asia Pacific consensus statements on Crohn's disease part 1: definition, diagnosis and epidemiology. J Gastroenterol Hepatol 2015, Epub ahead of print.
5. Ooi CJ, Fock KM, Makharia GK, Goh KL, Ling KL, Hilmi I, Lim WC, Kelvin T, Gibson PR, Gearry RB, Ouyang Q, Sollano J, Manatsathit S, Rerknimitr R, Wei SC, Leung WK, de Silva HJ, Leong RW; Asia Pacific Association of Gastroenterology Working Group on Inflammatory Bowel Disease: The Asia-Pacific consensus on ulcerative colitis. J Gastroenterol Hepatol 2010; 25: 453-468.
6. Leong RW, Armuzzi A, Ahmad T, Wong ML, Tse P, Jewell DP, Sung JJ: NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population. Aliment Pharmacol Ther 2003; 17: 1465-1470.
7. Lunney PC, Kariyawasam VC, Wang RR, Middleton KL, Huang T, Selinger CP, Andrews JM, Katelaris PH, Leong RW: Smoking prevalence and its influence on disease course and surgery in Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 2015; 42: 61-70.
8. Lunney PC, Leong RW: Review article: ulcerative colitis, smoking and nicotine therapy. Aliment Pharmacol Ther 2012; 36: 997-1008.
9. Leong RW, Lau JY, Sung JJ: The epidemiology and phenotype of Crohn's disease in the Chinese population. Inflamm Bowel Dis 2004; 10: 646-651.
10. Ko Y, Kariyawasam V, Karnib M, Butcher R, Samuel D, Alrubaie A, Rahme N, McDonald C, Cowlishaw J, Katelaris P, Barr G, Jones B, Connor S, Paven G, Chapman G, Park G, Gearry R, Leong RW; IBD Sydney Organisation: Inflammatory bowel disease environmental risk factors: A population-based case-control study of Middle Eastern migration to Australia. Clin Gastroenterol Hepatol 2015; 13: 1453-1463.e1.
11. Shivananda S, Lennard-Jones J, Logan R, Fear N, Price A, Carpenter L, van Blankenstein M: Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Gut 1996; 39: 690-697.
12. Strachan DP: Hay fever, hygiene, and household size. BMJ 1989; 299: 1259-1260.
13. Strachan DP, Aït-Khaled N, Foliaki S, Mallol J, Odhiambo J, Pearce N, Williams HC; ISAAC Phase Three Study Group: Siblings, asthma, rhinoconjunctivitis and eczema: A worldwide perspective from the international study of asthma and allergies in childhood. Clin Exp Allergy 2015; 45: 126-136.
14. Feillet H, Bach JF: Increased incidence of inflammatory bowel disease: The price of the decline of infectious burden? Curr Opin Gastroenterol 2004; 20: 560-564.
15. Yazdanbakhsh M, Kremsner PG, van Ree R: Allergy, parasites, and the hygiene hypothesis. Science 2002; 296: 490-494.
16. Saidel-Odes L, Odes S: Hygiene hypothesis in inflammatory bowel disease. Ann Gastroenterol 2014; 27: 189-190.
17. Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, Benchimol EI, Panaccione R, Ghosh S, Barkema HW, Kaplan GG: Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142: 46-54.
18. Ng SC, Tang W, Ching JY, Wong M, Chow CM, Hui AJ, Wong TC, Leung VK, Tsang SW, Yu HH, Li MF, Ng KK, Kamm MA, Studd C, Bell S, Leong R, de Silva HJ, Kasturiratne A, Mufeena MN, Ling KL, Ooi CJ, Tan PS, Ong D, Goh KL, Hilmi I, Pisespongsa P, Manatsathit S, Rerknimitr R, Aniwan S, Wang YF, Ouyang Q, Zeng Z, Zhu Z, Chen MH, Hu PJ, Wu K, Wang X, Simadibrata M, Abdullah M, Wu JC, Sung JJ, Chan FK; Asia-Pacific Crohn's and Colitis Epidemiologic Study (ACCESS) Study Group: Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study. Gastroenterology 2013; 145: 158-165.e2.
19. Burisch J, Jess T, Martinato M, Lakatos PL; ECCO-EpiCom: The burden of inflammatory bowel disease in Europe. J Crohns Colitis 2013; 7: 322-337.
20. Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D, Bortlik M, Shonová O, Vind I, Avnstrøm S, Thorsgaard N, Krabbe S, Andersen V, Dahlerup JF, Kjeldsen J, Salupere R, Olsen J, Nielsen KR, Manninen P, Collin P, Katsanos KH, Tsianos EV, Ladefoged K, Lakatos L, Ragnarsson G, Björnsson E, Bailey Y, O'Morain C, Schwartz D, Odes S, Giannotta M, Girardin G, Kiudelis G, Kupcinskas L, Turcan S, Barros L, Magro F, Lazar D, Goldis A, Nikulina I, Belousova E, Martinez-Ares D, Hernandez V, Almer S, Zhulina Y, Halfvarson J, Arebi N, Tsai HH, Sebastian S, Lakatos PL, Langholz E, Munkholm P; EpiCom-group: Environmental factors in a populationbased inception cohort of inflammatory bowel disease patients in Europe-an ECCO-EpiCom study. J Crohns Colitis 2014; 8: 607-616.
21. Khalili H, Huang ES, Ananthakrishnan AN, Higuchi L, Richter JM, Fuchs CS, Chan AT: Geographical variation and incidence of inflammatory bowel disease among US women. Gut 2012; 61: 1686-1692.
22. Bernstein CN, Rawsthorne P, Cheang M, Blanchard JF: A population-based case control study of potential risk factors for IBD. Am J Gastroenterol 2006; 101: 993-1002.
23. Amre DK, Lambrette P, Law L, Krupoves A, Chotard V, Costea F, Grimard G, Israel D, Mack D, Seidman EG: Investigating the hygiene hypothesis as a risk factor in pediatric onset Crohn's disease: A case-control study. Am J Gastroenterol 2006; 101: 1005-1011.
24. Gearry RB, Richardson AK, Frampton CM, Dodgshun AJ, Barclay ML: Population-based cases control study of inflammatory bowel disease risk factors. J Gastroenterol Hepatol 2010; 25: 325-333.
25. Gilat T, Hacohen D, Lilos P, Langman MJ: Childhood factors in ulcerative colitis and Crohn's disease. An international cooperative study. Scand J Gastroenterol 1987; 22: 1009-1024.
26. Ungaro R, Bernstein CN, Gearry R, Hviid A, Kolho KL, Kronman MP, Shaw S, Van Kruiningen H, Colombel JF, Atreja A: Antibiotics associated with increased risk of new-onset Crohn's disease but not ulcerative colitis: A meta-analysis. Am J Gastroenterol 2014; 109: 1728-1738.
27. Victoria CR, Sassak LY, Nunes HR: Incidence and prevalence rates of inflammatory bowel diseases, in midwestern of São Paulo State, Brazil. Arq Gastroenterol 2009; 46: 20-25.
28. Ministério da Saúde, Brazil. DATASUS. http://www2.datasus.gov.br/DATASUS/index.php (accessed 2014).
29. Das K, Ghoshal UC, Dhali GK, Benjamin J, Ahuja V, Makharia GK: Crohn's disease in India: A multicenter study from a country where tuberculosis is endemic. Dig Dis Sci 2009; 54: 1099-1107.
30. Thia KT, Loftus EV Jr, Sandborn WJ, Yang SK: An update on the epidemiology of inflammatory bowel disease in Asia. Am J Gastroenterol 2008; 103: 3167-3182.
31. Song MJ, Park DI, Hwang SJ, Kim ER, Kim YH, Jang BI, Lee SH, Ji JS, Shin SJ: [The prevalence of Helicobacter pylori infection in Korean patients with inflammatory bowel disease, a multicenter study]. Korean J Gastroenterol 2009; 53: 341-347.
32. Khalifa MM, Sharaf RR, Aziz RK: Helicobacter pylori: A poor man's gut pathogen? Gut Pathog 2010; 2: 2.
33. Sood A, Amre D, Midha V, Sharma S, Sood N, Thara A, Bansal M, Juyal G, Thelma BK, Seidman E: Low hygiene and exposure to infections may be associated with increased risk for ulcerative colitis in a North Indian population. Ann Gastroenterol 2014; 27: 219-223.
34. Ng SC, Tang W, Leong RW, et al: Environmental risk factors in inflammatory bowel disease: A population-based case-control study in Asia-Pacific. Gut 2015; 64: 1063-1071.
35. Ko Y, Butcher R, Leong RW: Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases. World J Gastroenterol 2014; 20: 1238-1247.
36. Barreiro-de Acosta M, Alvarez Castro A, Souto R, Iglesias M, Lorenzo A, Dominguez-Muñoz JE: Emigration to western industrialized countries: A risk factor for developing inflammatory bowel disease. J Crohns Colitis 2011; 5: 566-569.
37. Niv Y, Abuksis G, Fraser GM: Epidemiology of Crohn's disease in Israel: A survey of Israeli kibbutz settlements. Am J Gastroenterol 1999; 94: 2961-2965.
38. Odes HS, Fraser D, Krawiec J: Incidence of idiopathic ulcerative colitis in Jewish population subgroups in the Beer Sheva region of Israel. Am J Gastroenterol 1987; 82: 854-858.
39. Carr I, Mayberry JF: The effects of migration on ulcerative colitis: A three-year prospective study among Europeans and first-and secondgeneration South Asians in Leicester (1991-1994). Am J Gastroenterol 1999; 94: 2918-2922.
40. Li X, Sundquist J, Hemminki K, Sundquist K: Risk of inflammatory bowel disease in firstand second-generation immigrants in Sweden: A nationwide follow-up study. Inflamm Bowel Dis 2011; 17: 1784-1791.
41. Chen WX, Ren LH, Shi RH: Enteric microbiota leads to new therapeutic strategies for ulcerative colitis. World J Gastroenterol 2014; 20: 15657-15663.