Polygenic phenotypic plasticity moderates the effects of severe childhood abuse on depressive symptom severity in adulthood: A 5-year prospective cohort study

World Journal of Biological Psychiatry

Volumn 18, Issue 1, 2017, Pages 75-81

  Bousman, Chad A ^a,b   Gunn, Jane M ^a   Potiriadis, Maria ^a   Everall, Ian P ^a,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

^c NorthWestern Mental Health   (Australia)

Author keywords

child abuse; depression; differential susceptibility; Gene environment interaction; longitudinal

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CANNABINOID 1 RECEPTOR; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 5; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 18; NEUROLEPTIC AGENT; NORADRENALIN TRANSPORTER; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 3A RECEPTOR; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ADULT; ADULT DISEASE; ADULTHOOD; AGED; ANXIETY DISORDER; ARTICLE; CHILD SEXUAL ABUSE; COHORT ANALYSIS; COMORBIDITY; DISEASE SEVERITY; DNA POLYMORPHISM; DRUG USE; FEMALE; FOLLOW UP; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MEDICAL HISTORY; PANIC; PATIENT HEALTH QUESTIONNAIRE 9; PHENOTYPIC PLASTICITY; PHENOTYPIC PLASTICITY ALLELIC LOAD; PHYSICAL ABUSE; PRIMARY MEDICAL CARE; PROSPECTIVE STUDY; ANXIETY; CHILD ABUSE SURVIVOR; DEPRESSION; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; QUESTIONNAIRE; SEVERITY OF ILLNESS INDEX; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL; SUBSTANCE-RELATED DISORDERS;

ADULT; ADULT SURVIVORS OF CHILD ABUSE; ANXIETY; COMORBIDITY; DEPRESSION; FEMALE; GENE-ENVIRONMENT INTERACTION; GENOTYPE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; SUBSTANCE-RELATED DISORDERS; SURVEYS AND QUESTIONNAIRES;

EID: 84962338974     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2016.1153710     Document Type: Article

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