-
1
-
-
79953880772
-
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
-
COI: 1:CAS:528:DC%2BC3MXksFKjurg%3D, PID: 21422402
-
Gambacorti-Passerini C, Antolini L, Mahon FX, et al. Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst. 2011;103:553–61.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 553-561
-
-
Gambacorti-Passerini, C.1
Antolini, L.2
Mahon, F.X.3
-
3
-
-
84875515439
-
Structure, regulation, signaling, and targeting of Abl kinases in cancer
-
PID: 23226581
-
Hantschel O. Structure, regulation, signaling, and targeting of Abl kinases in cancer. Genes Cancer. 2012;3:436–46.
-
(2012)
Genes Cancer
, vol.3
, pp. 436-446
-
-
Hantschel, O.1
-
4
-
-
0020972981
-
Translocation of c-abl1 oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia
-
COI: 1:CAS:528:DyaL2cXhvVKrtw%3D%3D, PID: 6580527
-
Bartram CR, de Klein A, Hagemeijer A, et al. Translocation of c-abl1 oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia. Nature. 1983;306:277–80.
-
(1983)
Nature
, vol.306
, pp. 277-280
-
-
Bartram, C.R.1
de Klein, A.2
Hagemeijer, A.3
-
5
-
-
0021346853
-
Philadelphia chromosomal breakpoints are clustered within a limited region, BCR, on chromosome 22
-
COI: 1:CAS:528:DyaL2cXhtFGktrk%3D, PID: 6319012
-
Groffen J, Stephenson JR, Heisterkamp N, et al. Philadelphia chromosomal breakpoints are clustered within a limited region, BCR, on chromosome 22. Cell. 1984;36:93–9.
-
(1984)
Cell
, vol.36
, pp. 93-99
-
-
Groffen, J.1
Stephenson, J.R.2
Heisterkamp, N.3
-
6
-
-
84855913569
-
What do kinase inhibition profiles tell us about tyrosine kinase inhibitors used for the treatment of CML?
-
COI: 1:CAS:528:DC%2BC38Xht1WhtL0%3D, PID: 21996558
-
Deininger MW, Manley P. What do kinase inhibition profiles tell us about tyrosine kinase inhibitors used for the treatment of CML? Leuk Res. 2012;36:253–61.
-
(2012)
Leuk Res
, vol.36
, pp. 253-261
-
-
Deininger, M.W.1
Manley, P.2
-
7
-
-
84925947209
-
Management of adverse events associated with tyrosine kinase inhibitors in chronic myeloid leukemia
-
PID: 25814081, Most recent discussion of clinical management of TKI side effects
-
Rea D. Management of adverse events associated with tyrosine kinase inhibitors in chronic myeloid leukemia. Ann Hematol. 2015;94 Suppl 2:S149–58. Most recent discussion of clinical management of TKI side effects.
-
(2015)
Ann Hematol
, vol.94
, pp. 149-158
-
-
Rea, D.1
-
8
-
-
33845444046
-
Five-year follow-up for patients receiving imatinib for chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BD28Xht12ntrzM, PID: 17151364
-
Druker BJ, Guilhot F, O’Brien SG, et al. Five-year follow-up for patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006;355:2408–17.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O’Brien, S.G.3
-
9
-
-
84915745986
-
Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukaemia: results from the 24-month follow-up of the BELA trial
-
PID: 25196702, Randomized trial comparing the outcome and side effects of imatinib to bosutinib
-
Brummendorf TH, Cortes JE, de Souza AC, et al. Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukaemia: results from the 24-month follow-up of the BELA trial. Br J Haematol. 2014;168:69–81. Randomized trial comparing the outcome and side effects of imatinib to bosutinib.
-
(2014)
Br J Haematol
, vol.168
, pp. 69-81
-
-
Brummendorf, T.H.1
Cortes, J.E.2
de Souza, A.C.3
-
10
-
-
84893136765
-
Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)
-
COI: 1:CAS:528:DC%2BC2cXisFagsbc%3D, PID: 24311723, Randomized trial comparing the outcome and side effects of imatinib to dasatinib
-
Jabbour E, Kantarjian HM, Saglio G, et al. Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION). Blood. 2014;123:494–500. Randomized trial comparing the outcome and side effects of imatinib to dasatinib.
-
(2014)
Blood
, vol.123
, pp. 494-500
-
-
Jabbour, E.1
Kantarjian, H.M.2
Saglio, G.3
-
11
-
-
84867395848
-
Nilotinib vs. imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up
-
COI: 1:CAS:528:DC%2BC38XhsFSgu7zN, PID: 22699418, Randomized trial comparing the outcome of imatinib to nilotinib
-
Larson RA, Hochhaus A, Hughes TP, et al. Nilotinib vs. imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up. Leukemia. 2012;26:2197–203. Randomized trial comparing the outcome of imatinib to nilotinib.
-
(2012)
Leukemia
, vol.26
, pp. 2197-2203
-
-
Larson, R.A.1
Hochhaus, A.2
Hughes, T.P.3
-
12
-
-
84901281392
-
Comparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical use
-
Uitdehaag JC, de Roos JA, van Doornmalen AM, et al. Comparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical use. PLoS ONE. 2014;9:e921–46.
-
(2014)
PLoS ONE
, vol.9
, pp. 921-946
-
-
Uitdehaag, J.C.1
de Roos, J.A.2
van Doornmalen, A.M.3
-
13
-
-
74049125665
-
Molecular mechanisms of cardiovascular toxicity of targeted cancer therapeutics
-
COI: 1:CAS:528:DC%2BD1MXhs1aqt7nI, PID: 20056943
-
Cheng H, Force T. Molecular mechanisms of cardiovascular toxicity of targeted cancer therapeutics. Circ Res. 2010;106:21–34.
-
(2010)
Circ Res
, vol.106
, pp. 21-34
-
-
Cheng, H.1
Force, T.2
-
14
-
-
67349233062
-
Six-year follow-up of patients receiving imatinib for the first line treatment of chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BD1MXntFygt7w%3D, PID: 19282833
-
Hochhaus A, O’Brien SG, Guilhot F, et al. Six-year follow-up of patients receiving imatinib for the first line treatment of chronic myeloid leukemia. Leukemia. 2009;23:1054–61.
-
(2009)
Leukemia
, vol.23
, pp. 1054-1061
-
-
Hochhaus, A.1
O’Brien, S.G.2
Guilhot, F.3
-
15
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic phase chronic myeloid leukemia
-
PID: 12637609
-
O’Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic phase chronic myeloid leukemia. N Engl J Med. 2003;348:994–1004.
-
(2003)
N Engl J Med
, vol.348
, pp. 994-1004
-
-
O’Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
-
16
-
-
80055086681
-
Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population
-
COI: 1:CAS:528:DC%2BC3MXhsVGqu7vO, PID: 21750313
-
Efficace F, Baccarani M, Breccia M, et al. Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population. Blood. 2011;118:4554–60.
-
(2011)
Blood
, vol.118
, pp. 4554-4560
-
-
Efficace, F.1
Baccarani, M.2
Breccia, M.3
-
17
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BC3cXnvVaktbY%3D, PID: 20525995
-
Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362:2260–70.
-
(2010)
N Engl J Med
, vol.362
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
18
-
-
84905114999
-
Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib
-
COI: 1:CAS:528:DC%2BC2cXhtlKms7zI, PID: 24948656
-
Hughes TP, Lipton JH, Spector N, et al. Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib. Blood. 2014;124:729–36.
-
(2014)
Blood
, vol.124
, pp. 729-736
-
-
Hughes, T.P.1
Lipton, J.H.2
Spector, N.3
-
19
-
-
79251546724
-
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow up results
-
COI: 1:CAS:528:DC%2BC3MXhvFGksr8%3D, PID: 21098399
-
Kantarjian HM, Giles FJ, Bhalla KN, et al. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow up results. Blood. 2011;117:1141–5.
-
(2011)
Blood
, vol.117
, pp. 1141-1145
-
-
Kantarjian, H.M.1
Giles, F.J.2
Bhalla, K.N.3
-
20
-
-
84866175467
-
Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial
-
COI: 1:CAS:528:DC%2BC38XhslSksrfL, PID: 22949154
-
Cortes JE, Kim DW, Kantarjian HM, et al. Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial. J Clin Oncol. 2012;30:3486–92.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3486-3492
-
-
Cortes, J.E.1
Kim, D.W.2
Kantarjian, H.M.3
-
21
-
-
84923646835
-
EPIC: A phase 3 trial of ponatinib compared with imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CP-CML)
-
Lipton JH, Chuah C, Guerci-Bresler A, et al. EPIC: A phase 3 trial of ponatinib compared with imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CP-CML). Blood. Abstract 2014;124:519.
-
(2014)
Blood. Abstract
, vol.124
, pp. 519
-
-
Lipton, J.H.1
Chuah, C.2
Guerci-Bresler, A.3
-
22
-
-
84887127701
-
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias
-
COI: 1:CAS:528:DC%2BC3sXhslGhtLfK, PID: 24180494, First report on the efficacy and side effects of ponatinib
-
Cortes JE, Kim DW, Pinilla-Ibarz J, et al. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med. 2013;369:1783–96. First report on the efficacy and side effects of ponatinib.
-
(2013)
N Engl J Med
, vol.369
, pp. 1783-1796
-
-
Cortes, J.E.1
Kim, D.W.2
Pinilla-Ibarz, J.3
-
23
-
-
84899072118
-
Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study
-
COI: 1:CAS:528:DC%2BC2cXms1CjtLo%3D, PID: 24569263
-
Shah NP, Guilhot F, Cortes JE, et al. Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study. Blood. 2014;123:2317–24.
-
(2014)
Blood
, vol.123
, pp. 2317-2324
-
-
Shah, N.P.1
Guilhot, F.2
Cortes, J.E.3
-
24
-
-
84873568081
-
Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study
-
COI: 1:CAS:528:DC%2BC3sXntVCgtQ%3D%3D, PID: 22763385
-
Giles FJ, le Coutre PD, Pinilla-Ibarz J, et al. Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study. Leukemia. 2013;27:107–12.
-
(2013)
Leukemia
, vol.27
, pp. 107-112
-
-
Giles, F.J.1
le Coutre, P.D.2
Pinilla-Ibarz, J.3
-
25
-
-
84896622957
-
Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors
-
COI: 1:CAS:528:DC%2BC2cXkt1ajur0%3D, PID: 24345751
-
Kantarjian HM, Cortes JE, Kim DW, et al. Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors. Blood. 2014;123:1309–18.
-
(2014)
Blood
, vol.123
, pp. 1309-1318
-
-
Kantarjian, H.M.1
Cortes, J.E.2
Kim, D.W.3
-
26
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
COI: 1:CAS:528:DC%2BD3MXisVGktrc%3D, PID: 11248153
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001;344(11):783.
-
(2001)
N Engl J Med
, vol.344
, Issue.11
, pp. 783
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
27
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BD3MXivFGnu70%3D, PID: 11287972
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031–7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
28
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
Kerkela R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nature. 2006;12:908–16.
-
(2006)
Nature
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
-
29
-
-
34548030470
-
Congestive heart failure is a rare event in patients receiving imatinib therapy
-
Atallah E, Durand JB, Kantarjian H, et al. Congestive heart failure is a rare event in patients receiving imatinib therapy. Blood. 2007; 110.
-
(2007)
Blood
, pp. 110
-
-
Atallah, E.1
Durand, J.B.2
Kantarjian, H.3
-
30
-
-
70350072838
-
Cardiotoxicity induced by tyrosine kinase inhibitors
-
COI: 1:CAS:528:DC%2BD1MXhsVeku7fO, PID: 19734999
-
Orphanos GS, Ioannidis GN, Ardavanis AG. Cardiotoxicity induced by tyrosine kinase inhibitors. Acta Oncol. 2009;48:964–70.
-
(2009)
Acta Oncol
, vol.48
, pp. 964-970
-
-
Orphanos, G.S.1
Ioannidis, G.N.2
Ardavanis, A.G.3
-
31
-
-
84887076805
-
Cancer-drug discovery and cardiovascular surveillance
-
COI: 1:CAS:528:DC%2BC3sXhslGhtLfJ, PID: 24180496
-
Groarke JD, Cheng S, Moslehi J. Cancer-drug discovery and cardiovascular surveillance. N Engl J Med. 2013;369:1779–81.
-
(2013)
N Engl J Med
, vol.369
, pp. 1779-1781
-
-
Groarke, J.D.1
Cheng, S.2
Moslehi, J.3
-
32
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
COI: 1:CAS:528:DC%2BD2sXksFSiu7w%3D
-
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nature. 2007;7:332–44.
-
(2007)
Nature
, vol.7
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
33
-
-
84921405856
-
Conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting tyrosine kinase inhibitor-based therapy
-
COI: 1:CAS:528:DC%2BC2MXhsF2iu7w%3D, PID: 25494575
-
Bronte G, Bronte E, Novo G, et al. Conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting tyrosine kinase inhibitor-based therapy. Expert Opin Drug Saf. 2015;14:253–67.
-
(2015)
Expert Opin Drug Saf
, vol.14
, pp. 253-267
-
-
Bronte, G.1
Bronte, E.2
Novo, G.3
-
34
-
-
84929289846
-
Safety and efficacy of imatinib in CML over a period of 10 years: data from the randomized CML-study IV
-
COI: 1:CAS:528:DC%2BC2MXks1aitbw%3D, PID: 25676422, Long-term study showing the side effects of imatinib and nilotinib
-
Kalmanti L, Saussele S, Lauseker M, et al. Safety and efficacy of imatinib in CML over a period of 10 years: data from the randomized CML-study IV. Leukemia. 2015;29:1123–32. Long-term study showing the side effects of imatinib and nilotinib.
-
(2015)
Leukemia
, vol.29
, pp. 1123-1132
-
-
Kalmanti, L.1
Saussele, S.2
Lauseker, M.3
-
35
-
-
84940757131
-
Long-term outcome of chronic myeloid leukemia patients treated frontline with imatinib
-
COI: 1:CAS:528:DC%2BC2MXhtFOisrvP, PID: 26088952
-
Castagnetti F, Gugliotta G, Breccia M. Long-term outcome of chronic myeloid leukemia patients treated frontline with imatinib. Leukemia. 2015;29:1823–31.
-
(2015)
Leukemia
, vol.29
, pp. 1823-1831
-
-
Castagnetti, F.1
Gugliotta, G.2
Breccia, M.3
-
37
-
-
84979489901
-
-
Iclusig (ponatinib) [package insert]. Cambridge, MA: ARIAD Pharmaceuticals, Inc.;2012
-
Iclusig (ponatinib) [package insert]. Cambridge, MA: ARIAD Pharmaceuticals, Inc.;2012.
-
-
-
-
38
-
-
84979486890
-
-
Cortes JE, Saglio G, Baccarani M, et al. Final study results of the phase 3 dasatinib vs. imatinib in newly diagnosed chronic myeloid leukemia (CML-CP) trial (DASISION). Blood. Abstract. 2014;124(21):152. Long-term toxicities of imatinib and dasatinib show differences
-
Cortes JE, Saglio G, Baccarani M, et al. Final study results of the phase 3 dasatinib vs. imatinib in newly diagnosed chronic myeloid leukemia (CML-CP) trial (DASISION). Blood. Abstract. 2014;124(21):152. Long-term toxicities of imatinib and dasatinib show differences.
-
-
-
-
39
-
-
84979489048
-
-
Larson RA, Kim DW, Issaragrilsil S, et al. Efficacy and safety of nilotinib (NIL) vs imatinib (IM) in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): long-term follow-up of ENESTnd. Blood. Abstract. 2014;124:4541. Long-term side effects comparing imatinib and nilotinib show differences
-
Larson RA, Kim DW, Issaragrilsil S, et al. Efficacy and safety of nilotinib (NIL) vs imatinib (IM) in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): long-term follow-up of ENESTnd. Blood. Abstract. 2014;124:4541. Long-term side effects comparing imatinib and nilotinib show differences.
-
-
-
-
41
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
PID: 16775235
-
Kantarjian H, Giles F, Wunderle L, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med. 2006;354:2542–51.
-
(2006)
N Engl J Med
, vol.354
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
-
42
-
-
36348968931
-
Nilotinib, a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive CML-CP following imatinib resistance and intolerance
-
COI: 1:CAS:528:DC%2BD2sXhtlarur3P, PID: 17715389
-
Kantarjian HM, Giles F, Gattermann N, et al. Nilotinib, a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive CML-CP following imatinib resistance and intolerance. Blood. 2007;110(10):3540–6.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
-
43
-
-
84925632458
-
Increased risk of cardiovascular events associated with TKI treatment in chronic phase chronic myeloid leukemia: data from Swedish population-based registries
-
Dahlen T, Edgren G, Hoglund M, et al. Increased risk of cardiovascular events associated with TKI treatment in chronic phase chronic myeloid leukemia: data from Swedish population-based registries. Blood. Abstract 2014;124:3134
-
(2014)
Blood. Abstract
, vol.124
, pp. 3134
-
-
Dahlen, T.1
Edgren, G.2
Hoglund, M.3
-
44
-
-
84857234082
-
Nilotinib-mediated increase in fasting glucose level is reversible, does not convert to type 2 diabetes, and is likely correlated with increase body mass index
-
Breccia M, Loglisci G, Salaroli A, et al. Nilotinib-mediated increase in fasting glucose level is reversible, does not convert to type 2 diabetes, and is likely correlated with increase body mass index. Leuk Res. 2012; e66-e67.
-
(2012)
Leuk Res
, pp. 66-67
-
-
Breccia, M.1
Loglisci, G.2
Salaroli, A.3
-
45
-
-
84903581440
-
Early onset hypercholesterolemia induced by the 2nd-generation tyrosine kinase inhibitor nilotinib in patients with chronic phase-chronic myeloid leukemia
-
Rea D, Mirault T, Cluzeau T, et al. Early onset hypercholesterolemia induced by the 2nd-generation tyrosine kinase inhibitor nilotinib in patients with chronic phase-chronic myeloid leukemia. Haematolgica. 2014;99:1197–203.
-
(2014)
Haematolgica
, vol.99
, pp. 1197-1203
-
-
Rea, D.1
Mirault, T.2
Cluzeau, T.3
-
46
-
-
84878899268
-
Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis
-
COI: 1:CAS:528:DC%2BC3sXptFektrs%3D, PID: 23459450
-
Giles FJ, Mauro MJ, Hong F, et al. Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis. Leukemia. 2013;27:1310–15.
-
(2013)
Leukemia
, vol.27
, pp. 1310-1315
-
-
Giles, F.J.1
Mauro, M.J.2
Hong, F.3
-
47
-
-
79959361633
-
Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML
-
COI: 1:CAS:528:DC%2BC3MXns1Shtb0%3D, PID: 21538470
-
Aichberger KJ, Herndhofer S, Schernthaner GH, et al. Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML. Am J Hematol. 2011;86:533–9.
-
(2011)
Am J Hematol
, vol.86
, pp. 533-539
-
-
Aichberger, K.J.1
Herndhofer, S.2
Schernthaner, G.H.3
-
48
-
-
80052649493
-
Severe peripheral arterial disease during nilotinib therapy
-
PID: 21813414
-
Le Coutre P, Rea D, Abruzzese E, et al. Severe peripheral arterial disease during nilotinib therapy. J Natl Cancer Inst. 2011;103:1347–8.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1347-1348
-
-
Le Coutre, P.1
Rea, D.2
Abruzzese, E.3
-
50
-
-
84878133368
-
Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in chronic myeloid leukemia: a single institution study
-
COI: 1:CAS:528:DC%2BC3sXpvVOktbg%3D, PID: 23506097
-
Levato L, Cantaffa R, Kroop MD, et al. Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in chronic myeloid leukemia: a single institution study. Eur J Haematol. 2013;90:531–2.
-
(2013)
Eur J Haematol
, vol.90
, pp. 531-532
-
-
Levato, L.1
Cantaffa, R.2
Kroop, M.D.3
-
51
-
-
84940914196
-
Long-term outcome of a phase 2 trial with nilotinib 400 mg twice daily in first-line treatment of chronic myeloid leukemia
-
PID: 26113419
-
Gugliotta G, Castagnetti F, Breccia M, et al. Long-term outcome of a phase 2 trial with nilotinib 400 mg twice daily in first-line treatment of chronic myeloid leukemia. Haematologica. 2015;100:1146–50.
-
(2015)
Haematologica
, vol.100
, pp. 1146-1150
-
-
Gugliotta, G.1
Castagnetti, F.2
Breccia, M.3
-
52
-
-
84878910858
-
Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib
-
COI: 1:CAS:528:DC%2BC3sXptFeksbY%3D, PID: 23459449
-
Kim TD, Rea D, Schwarz M, et al. Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib. Leukemia. 2013;27:1316–21.
-
(2013)
Leukemia
, vol.27
, pp. 1316-1321
-
-
Kim, T.D.1
Rea, D.2
Schwarz, M.3
-
53
-
-
84922373381
-
Application of systematic coronary risk evaluation chart to identify chronic myeloid leukemia patients at risk of cardiovascular diseases during nilotinib treatment
-
COI: 1:CAS:528:DC%2BC2cXhslCisLfL, PID: 25304102
-
Breccia M, Molica M, Zacheo I, et al. Application of systematic coronary risk evaluation chart to identify chronic myeloid leukemia patients at risk of cardiovascular diseases during nilotinib treatment. Ann Hematol. 2015;94:393–7.
-
(2015)
Ann Hematol
, vol.94
, pp. 393-397
-
-
Breccia, M.1
Molica, M.2
Zacheo, I.3
-
54
-
-
84883741352
-
Nilotinib treatment-associated accelerated atherosclerosis: when is the risk justified?
-
COI: 1:CAS:528:DC%2BC3sXhsVWqtrvJ, PID: 23604230
-
Tefferi A. Nilotinib treatment-associated accelerated atherosclerosis: when is the risk justified? Leukemia. 2013;27:1939–40.
-
(2013)
Leukemia
, vol.27
, pp. 1939-1940
-
-
Tefferi, A.1
-
55
-
-
84954204455
-
Ponatinib as first-line treatment for patients with chronic myeloid leukemia in chronic phase: a phase 2 study
-
PID: 26436130
-
Jain P, Kantarjian H, Jabbour E, et al. Ponatinib as first-line treatment for patients with chronic myeloid leukemia in chronic phase: a phase 2 study. Lancet. 2015;2:e376–83.
-
(2015)
Lancet
, vol.2
, pp. 376-383
-
-
Jain, P.1
Kantarjian, H.2
Jabbour, E.3
-
56
-
-
84897895722
-
Optimizing tolerability of TKI therapy in CML
-
COI: 1:CAS:528:DC%2BC2cXkt1ajtb0%3D, PID: 24578491
-
Hochhaus A. Optimizing tolerability of TKI therapy in CML. Blood. 2014;123:1284.
-
(2014)
Blood
, vol.123
, pp. 1284
-
-
Hochhaus, A.1
-
57
-
-
84922342262
-
Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors
-
COI: 1:CAS:528:DC%2BC2MXislGgs7g%3D, PID: 25525119, Review of cardiovascular toxicities of TKIs with discussion of how these toxicities were initially overlooked
-
Valent P, Hadzijusufovic E, Schernthaner GH, et al. Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors. Blood. 2015;125:901–6. Review of cardiovascular toxicities of TKIs with discussion of how these toxicities were initially overlooked.
-
(2015)
Blood
, vol.125
, pp. 901-906
-
-
Valent, P.1
Hadzijusufovic, E.2
Schernthaner, G.H.3
-
58
-
-
84957552953
-
-
Moslehi JJ, Deininger M. Tyrosine Kinase Inhibitor-Associated Cardiovascular Toxicity in Chronic Myeloid Leukemia. J Clin Oncol. 2015;33. Important review of the published data on cardiovascular toxicities
-
Moslehi JJ, Deininger M. Tyrosine Kinase Inhibitor-Associated Cardiovascular Toxicity in Chronic Myeloid Leukemia. J Clin Oncol. 2015;33. Important review of the published data on cardiovascular toxicities.
-
-
-
-
59
-
-
84937879454
-
Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML Study IV
-
COI: 1:CAS:528:DC%2BC2MXhtleqt7jF, PID: 25918346, Co-morbidities in responsive patients appear to have major impact upon survival in CML
-
Saussele S, Krauss MP, Hehlmann R, et al. Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML Study IV. Blood. 2015;126:42–9. Co-morbidities in responsive patients appear to have major impact upon survival in CML.
-
(2015)
Blood
, vol.126
, pp. 42-49
-
-
Saussele, S.1
Krauss, M.P.2
Hehlmann, R.3
-
60
-
-
33744467685
-
Twenty-seven cases of drug-induced interstitial lung disease associated with imatinib mesylate
-
COI: 1:CAS:528:DC%2BD28XkvVymur8%3D, PID: 16598305
-
Ohnishi K, Sakai F, Kudoh S, et al. Twenty-seven cases of drug-induced interstitial lung disease associated with imatinib mesylate. Leukemia. 2006;20:1162–4.
-
(2006)
Leukemia
, vol.20
, pp. 1162-1164
-
-
Ohnishi, K.1
Sakai, F.2
Kudoh, S.3
-
62
-
-
84884676225
-
Nilotinib-induced interstitial lung disease
-
PID: 23877149
-
Go SI, Lee WS, Kang JH, et al. Nilotinib-induced interstitial lung disease. Int J Hematol. 2013;98:361–5.
-
(2013)
Int J Hematol
, vol.98
, pp. 361-365
-
-
Go, S.I.1
Lee, W.S.2
Kang, J.H.3
-
63
-
-
84944522481
-
Clinical features of pulmonary arterial hypertension in patients receiving dasatinib
-
COI: 1:CAS:528:DC%2BC2MXhslegurzK, PID: 26284693
-
Shah NP, Wallis N, Farber HW, et al. Clinical features of pulmonary arterial hypertension in patients receiving dasatinib. Am J Hematol. 2015;90:1060–4.
-
(2015)
Am J Hematol
, vol.90
, pp. 1060-1064
-
-
Shah, N.P.1
Wallis, N.2
Farber, H.W.3
-
65
-
-
66649092089
-
Bleeding diathesis in patients with chronic myelogenous leukemia receiving dasatinib therapy
-
COI: 1:CAS:528:DC%2BD1MXmvVyhs7Y%3D, PID: 19280591
-
Quintas-Cardama A, Kantarjian H, Ravendi F, et al. Bleeding diathesis in patients with chronic myelogenous leukemia receiving dasatinib therapy. Cancer. 2009;115:2482–90.
-
(2009)
Cancer
, vol.115
, pp. 2482-2490
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Ravendi, F.3
-
66
-
-
67651089848
-
Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BD1MXovVKmu7w%3D, PID: 19414863
-
Quintas-Cardama A, Han X, Kantarjian H, et al. Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia. Blood. 2009;114:261–3.
-
(2009)
Blood
, vol.114
, pp. 261-263
-
-
Quintas-Cardama, A.1
Han, X.2
Kantarjian, H.3
-
67
-
-
84891862685
-
Haematologic colitis caused By dasatinib
-
Patodi N, Sagar N, Rudzki Z, et al. Haematologic colitis caused By dasatinib. Case Rep Hematol. 2012;2012:ID 417106.
-
(2012)
Case Rep Hematol
, vol.2012
, pp. 417106
-
-
Patodi, N.1
Sagar, N.2
Rudzki, Z.3
-
68
-
-
84933677603
-
Chronic myeloid leukaemia
-
PID: 25484026
-
Apperley JF. Chronic myeloid leukaemia. Lancet. 2015;385:1447–59.
-
(2015)
Lancet
, vol.385
, pp. 1447-1459
-
-
Apperley, J.F.1
-
69
-
-
84879896214
-
Hepatotoxicity of tyrosine kinase inhibitors: clinical and regulatory perspectives
-
COI: 1:CAS:528:DC%2BC3sXhsl2nsLzO, PID: 23620168
-
Shah RR, Morganroth J, Shah DR. Hepatotoxicity of tyrosine kinase inhibitors: clinical and regulatory perspectives. Drug Saf. 2013;36:491–503.
-
(2013)
Drug Saf
, vol.36
, pp. 491-503
-
-
Shah, R.R.1
Morganroth, J.2
Shah, D.R.3
-
70
-
-
84979489733
-
Pfizer Laboratories Div
-
Bosulif (bosutinib) [package insert]. New York, NY: Pfizer Laboratories Div. Pfizer Inc.; 2012.
-
(2012)
Pfizer Inc.
-
-
-
72
-
-
79960955609
-
Imatinib treatment duration is related to decreased estimated glomerular filtration rate in chronic myeloid leukemia patients
-
COI: 1:STN:280:DC%2BC3MjpvVWjsg%3D%3D, PID: 21310760
-
Marcolino MS, Boersma E, Clementino NCD, et al. Imatinib treatment duration is related to decreased estimated glomerular filtration rate in chronic myeloid leukemia patients. Ann Oncol. 2011;22:2073–9.
-
(2011)
Ann Oncol
, vol.22
, pp. 2073-2079
-
-
Marcolino, M.S.1
Boersma, E.2
Clementino, N.C.D.3
-
73
-
-
84945490814
-
Estimated glomerular filtration rate changes in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
-
COI: 1:CAS:528:DC%2BC2MXhslegtb7N, PID: 26217876
-
Yilmaz M, Lahoti A, O’Brien S, et al. Estimated glomerular filtration rate changes in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. Cancer. 2015;121:3894–904.
-
(2015)
Cancer
, vol.121
, pp. 3894-3904
-
-
Yilmaz, M.1
Lahoti, A.2
O’Brien, S.3
-
74
-
-
79952279792
-
Uncommon or delayed adverse events associated with imatinib treatment for chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BC3cXhsFyhu7vF, PID: 21030345
-
Salie R, Silver RT. Uncommon or delayed adverse events associated with imatinib treatment for chronic myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2010;10:331–5.
-
(2010)
Clin Lymphoma Myeloma Leuk
, vol.10
, pp. 331-335
-
-
Salie, R.1
Silver, R.T.2
-
75
-
-
33646482407
-
Altered bone and mineral metabolism in patients receiving imatinib mesylate
-
COI: 1:CAS:528:DC%2BD28XksFGhs7s%3D, PID: 16687713
-
Berman E, Nicolaides M, Maki RG, et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med. 2006;354:2006–13.
-
(2006)
N Engl J Med
, vol.354
, pp. 2006-2013
-
-
Berman, E.1
Nicolaides, M.2
Maki, R.G.3
-
76
-
-
84903600991
-
Girotra M Effects of tyrosine kinase inhibition on bone metabolism: untargeted consequences of targeted therapies
-
COI: 1:CAS:528:DC%2BC2cXhtlOmsbrJ, PID: 24478055
-
Aleman JO, Farooki A. Girotra M Effects of tyrosine kinase inhibition on bone metabolism: untargeted consequences of targeted therapies. Endocr Relat Cancer. 2014;21:R247–59.
-
(2014)
Endocr Relat Cancer
, vol.21
, pp. 247-259
-
-
Aleman, J.O.1
Farooki, A.2
-
77
-
-
84887615220
-
Chronic myeloproliferative neoplasms and risk of osteoporotic fractures; a nationwide population-based cohort study
-
Farmer S, Horvath-Puho E, Vestergaard H, et al. Chronic myeloproliferative neoplasms and risk of osteoporotic fractures; a nationwide population-based cohort study. Brit J Haematol. 2013;163:603–10.
-
(2013)
Brit J Haematol
, vol.163
, pp. 603-610
-
-
Farmer, S.1
Horvath-Puho, E.2
Vestergaard, H.3
-
78
-
-
84925225766
-
Growth deceleration in children treated with imatinib for chronic myeloid leukemia
-
COI: 1:CAS:528:DC%2BC2cXhsl2ksLfE, PID: 25459396
-
Millot F, Guilhot J, Baruchel A, et al. Growth deceleration in children treated with imatinib for chronic myeloid leukemia. Eur J Cancer. 2014;50:3206–11.
-
(2014)
Eur J Cancer
, vol.50
, pp. 3206-3211
-
-
Millot, F.1
Guilhot, J.2
Baruchel, A.3
-
79
-
-
84878255303
-
Growth failure in children with chronic myeloid leukemia receiving imatinib is due to disruption of GH/IGF-1 axis
-
COI: 1:CAS:528:DC%2BC2cXhslWhu7fN, PID: 23322583
-
Narayanan KR, Bansal D, Walia R, et al. Growth failure in children with chronic myeloid leukemia receiving imatinib is due to disruption of GH/IGF-1 axis. Pediatr Blood Cancer. 2013;60:1148–53.
-
(2013)
Pediatr Blood Cancer
, vol.60
, pp. 1148-1153
-
-
Narayanan, K.R.1
Bansal, D.2
Walia, R.3
-
80
-
-
84874539068
-
Bone mineral metabolism, growth rate and pubertal development in children with chronic myeloid leukemia treated with imatinib during puberty
-
Giona F, Mariani S, Gnessi L, et al. Bone mineral metabolism, growth rate and pubertal development in children with chronic myeloid leukemia treated with imatinib during puberty. Haematolgica. 2013;98:e25–7.
-
(2013)
Haematolgica
, vol.98
, pp. 25-27
-
-
Giona, F.1
Mariani, S.2
Gnessi, L.3
-
81
-
-
10744230733
-
Gynaecomastia in men with chronic myeloid leukemia after imatinib
-
PID: 12801741
-
Gambacorti-Passerini C, Tornaghi L, Cavagnini F, et al. Gynaecomastia in men with chronic myeloid leukemia after imatinib. Lancet. 2003;361:1954–6.
-
(2003)
Lancet
, vol.361
, pp. 1954-1956
-
-
Gambacorti-Passerini, C.1
Tornaghi, L.2
Cavagnini, F.3
-
82
-
-
33644984905
-
Epidemiologic analysis of second primary malignancies in more than 9,500 patients treated with imatinib
-
COI: 1:STN:280:DC%2BD283hvFWmtg%3D%3D, PID: 16292349
-
Pilot PR, Sablinska K, Owen S, et al. Epidemiologic analysis of second primary malignancies in more than 9,500 patients treated with imatinib. Leukemia. 2006;20:148.
-
(2006)
Leukemia
, vol.20
, pp. 148
-
-
Pilot, P.R.1
Sablinska, K.2
Owen, S.3
-
83
-
-
80054833185
-
Malignancies occurring during therapy with tyrosine kinase inhibitors for chronic myeloid leukemia and other hematologic malignancies
-
COI: 1:CAS:528:DC%2BC3MXhsVKjsrjE, PID: 21846902
-
Verma D, Kantarjian H, Strom S, et al. Malignancies occurring during therapy with tyrosine kinase inhibitors for chronic myeloid leukemia and other hematologic malignancies. Blood. 2011;118:4353–8.
-
(2011)
Blood
, vol.118
, pp. 4353-4358
-
-
Verma, D.1
Kantarjian, H.2
Strom, S.3
-
84
-
-
84904302949
-
The occurrence of second neoplasms after treatment with tyrosine kinase inhibitors for chronic myeloid leukemia
-
PID: 23697842
-
Togasaki-Yoshimoto E, Shono K, Onoda M, et al. The occurrence of second neoplasms after treatment with tyrosine kinase inhibitors for chronic myeloid leukemia. Leuk Lymphoma. 2014;55:453–6.
-
(2014)
Leuk Lymphoma
, vol.55
, pp. 453-456
-
-
Togasaki-Yoshimoto, E.1
Shono, K.2
Onoda, M.3
-
85
-
-
84929234796
-
Second malignancies following treatment of chronic myeloid leukaemia in the tyrosine kinase inhibitor era
-
COI: 1:CAS:528:DC%2BC2MXosVajtrg%3D, PID: 25817799, Long-term concern is reopened regarding second malignancies from this retrospective population-based study
-
Gunnarsson N, Stenke L, Hoglund M, et al. Second malignancies following treatment of chronic myeloid leukaemia in the tyrosine kinase inhibitor era. Br J Haematol. 2015;169:683–8. Long-term concern is reopened regarding second malignancies from this retrospective population-based study.
-
(2015)
Br J Haematol
, vol.169
, pp. 683-688
-
-
Gunnarsson, N.1
Stenke, L.2
Hoglund, M.3
-
86
-
-
84943334087
-
Occurrence of secondary malignancies in chronic myeloid leukemia during therapy with imatinib mesylate-single institution experience
-
PID: 25574362
-
Helbig G, Bober G, Seweryn M, et al. Occurrence of secondary malignancies in chronic myeloid leukemia during therapy with imatinib mesylate-single institution experience. Mediterr J Hematol Infect Dis. 2015;7:e2015003.
-
(2015)
Mediterr J Hematol Infect Dis
, vol.7
, pp. 2015003
-
-
Helbig, G.1
Bober, G.2
Seweryn, M.3
-
87
-
-
84865006789
-
Secondary malignancy after imatinib therapy: eight cases and review of the literature
-
COI: 1:CAS:528:DC%2BC38XhtFOkur7L, PID: 22329351
-
Duman BB, Paydas S, Disel U, et al. Secondary malignancy after imatinib therapy: eight cases and review of the literature. Leuk Lymphoma. 2012;53:1706–8.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 1706-1708
-
-
Duman, B.B.1
Paydas, S.2
Disel, U.3
|